LOCUS       XM_039096618            6796 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus rotatin (Rttn), transcript variant X4,
            mRNA.
ACCESSION   XM_039096618
VERSION     XM_039096618.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051353.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039096618.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6796
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6796
                     /gene="Rttn"
                     /note="rotatin; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 1 mRNA, 6 ESTs, 1
                     Protein, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 5 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:291377"
                     /db_xref="RGD:1306706"
     CDS             151..6441
                     /gene="Rttn"
                     /codon_start=1
                     /product="rotatin isoform X4"
                     /protein_id="XP_038952546.1"
                     /db_xref="GeneID:291377"
                     /db_xref="RGD:1306706"
                     /translation="MLEMYQASNVDSSKDSMSTYQATVGFGIIQWGNPTVKWLRFSVF
                     PWLPLTTTDRHVLSSNESSLRSSNHTLIWNTCELLKDVIMQDFPAEIFLQRPKIVQGL
                     LCLVKLAFGGDGKHRLALQSVSCLQQLCTSLRNRLNFYRDPNLFSNKQDTISQNSSLS
                     YCHEARGPYHSPNPSPGSSSSRPSVVGRTGQRPRGDGQDWDAVSSSGSSSHAHVNSRL
                     SVRSPLDVAHADLPELETEDALELHFQQLSLPQFCISTLDAAVPLLRTGSREMVIRVL
                     ELLGEDLLLIGQAISSEIWDDNSLFAIDVKEKLLQVLGSLGETMCYRKTSFSLEQAEA
                     ILVHHRMAFVSISLFTVRLLQILLPVEKASEFLPESMSAALFFVSLDMPISLEYPEIH
                     DTVVAYLEQLDSENYSIYKRTAEAVYSIECTCNFLSDVGKEGEKNLLELVELADQALR
                     SFSYHQHSPLIKEVICLCSKIWKSAQASPLLQGESQKVFLHMLSHPLPQVKVETYQCC
                     LEIVKECLGVHNVTKPVSSLCSGIHFLLHPKVLYEISAFGIQESKNEVNAAAKAVLLY
                     LLQGRFMMTALTWNKFIESLCPVIPVLQGYADTEDPLGNCILLLSKVSSETGEGILPC
                     TTRLKSVLRLLLVKKPSVRSLALKLLAFHLTGEEGADTKRPFVDARVLSRVTNLFIVK
                     KPIDLKLDDRRELVIKLETVKKVYEIFTSDDVDLVLRKSAAEQLAVIMQDIKMHTVVK
                     KLCLIEKIIGYLNEFVGQDGKVIECLIRPCLTLLRKVVCADLVIRASLSQQASLLTLL
                     LRVSLIFHEDCAVVAEVGALFCLLLFDEVSRMDMWSDNSSNKPSLSSVFSLPVSVFRR
                     YHLPVYVNGHHAVSPYSIVLPLSTECLALKPVSDMLRIAWNLAWYHGSDNLLKQTTSE
                     TKIQEFSDTLQLSTEDILTLKITYTDSGLKDCLQSIVQAGGHRDVRAAITRMSFYLLN
                     DKLSLKDDIGPCGFTLKSLAWHTVLNRFLQVLPACTEDEKLLIDIIHFLNKLIKEQRK
                     NPSVELLNWILELLLRHNPNPLLDLLVLTESHTREVTDEIRTAVRQQLQKELITLLNS
                     LLLVCMTVSDRKCLELFYVFQTQLSLKLLQCLRVTDAPHFYGLPSLERTLAGMAHLTA
                     SPGWSAHSPLSKPLEICGKYLSGLLEVITSFYVERGGNAMSFMGKGVTKSTVLCLLHL
                     SHEMIVQAPNSEWMPLWFLPLGSHSEENVPSQQGLAWLIPLWVDRDPEVRFTSLGLGS
                     ALTTMEAGCVALANSCQNISGGLWGTVVNILLDQSECSMVRREAAFILQNLLVIPMPS
                     KVIKDYTWQGPCVHDEDSGLSLSGKPALQALLYHCRFYEHLTHMVKHCYVGRYMFDFN
                     ISAFTETSEYNDLNGLDDSFKFWRAPSGTSTQDHEPSSLSTSETMVAASVVSAEIQPL
                     LPSTLLPEPAALDQFVTQGQPEVRPVRPRDSSPSASLHRQCVFVTPSLLSAVCSLLDN
                     LLAVTPRDAANAFQQAHLIELLCSTMDASLLEMCVQELKTPLSLSSAVEHTQAQTSFF
                     LEYLSSLFQLLKSCLLVDPKLVTQDELLKPLITNVIRVLIVCTKDVLDVQLVLAFHRT
                     WTHLFDLLATLLRKAGAVSLVPLTSALAKHWEAVTDTLCRCVGLSVKCPALSIASLQF
                     LSVLLAEEEKRRVQDKDKTNACQTPTVAFLLDGTQGSLRSSERLNETILQCYEGISSK
                     DVLKRVAANALMSLLAVSRRAQRHALKSDLIENCVEQMKHINAQLNLDVLRPGKAALK
                     KKEDGIIKELSITLQLLRNCLYQNEECKVAAFEAHLVPVLHSLWPWLLMEDSLMQIAL
                     QLLCVYTANFPTGCSSLCWSNYGQYIQTAHRGTPSSSLILCALKLASQVPAENTPIQQ
                     AVFMFLSNLALSHDCKGVIQKSNFLQHFLSLTLPKGGNQHLSNVTILWLKLLLNMSFG
                     EDGQQMILRLDGCLDLLIEMSKYTHKSSPHVPLLIFHNICCSPANKPKILANEKVVTL
                     LATCLESENQNAQRIGAASLWALTYNYQKAKATLKNPSIKRKIDEAYSIAKRTFSNSE
                     EDPLNSYYLKCLENLVQLLNCS"
ORIGIN      
        1 ccaacctgat caaaatgaat tgtcacaaca acctgaagtt ttaacaggct attttcccca
       61 agacaaaagt aatctccagc agatggaagt cccaccaggg ccagtggtgt aataagctgt
      121 gacagcccct ctttctcagt atttgaacca atgctagaaa tgtatcaggc atccaatgtg
      181 gactcttcaa aggattcaat gagtacttac caagccacag tgggatttgg tattatccaa
      241 tggggaaacc caactgtgaa gtggctgagg ttctctgtgt ttccttggct acccctgacc
      301 acaacagaca gacatgttct ctcctccaat gaaagctcct tgagaagtag taaccacact
      361 ctgatctgga acacctgtga gcttctgaag gacgtgatca tgcaagactt tcctgcggag
      421 atttttcttc agaggcctaa gattgttcag ggccttttgt gtctggtgaa gctggccttt
      481 ggaggagatg ggaagcatcg tctcgcctta cagtcagtgt cctgtttgca gcagctgtgc
      541 acaagcttaa gaaacagact caacttttac agagatccca accttttctc gaataaacaa
      601 gacacaatct cccagaattc ttctttgtct tactgtcatg aagcaagagg tccttaccat
      661 tccccaaacc cgtccccagg aagcagtagc tctcggcctt ccgtggttgg gcgtacaggc
      721 cagcgacccc gaggagatgg ccaggactgg gatgcagtgt cttccagcgg gagcagcagt
      781 cacgcacatg tgaactctag gctgtctgtg cgttctccct tggatgtggc gcatgcagat
      841 ctgccggagc tggaaacaga ggacgcattg gagctgcact tccagcagct tagtcttcct
      901 cagttctgca tctccaccct ggacgcagca gtccctctgc tgaggacagg tagcagagaa
      961 atggtaataa gagttttgga actgcttgga gaggacctgt tgctcattgg acaagcaatt
     1021 tcatctgaaa tctgggatga taacagcctt tttgctatag atgtgaaaga gaaactgctc
     1081 caagtgttgg ggtcccttgg agaaactatg tgctaccgaa agaccagttt tagcttggag
     1141 caagcagagg ctatactagt gcaccacagg atggcctttg tcagcatctc actgttcacc
     1201 gttcgactgt tacaaattct tctccctgtt gaaaaggcta gtgagttttt gccagagtcc
     1261 atgtcagcag cattattttt tgtctcgttg gacatgccta tttctttgga atatccagag
     1321 attcatgaca ctgttgtggc ttatttggaa cagctggatt ctgaaaatta cagcatttat
     1381 aagcgaactg cagaggctgt ttattcaatt gaatgtacct gtaacttcct atctgatgtg
     1441 gggaaagagg gagaaaagaa tctcctagaa ttagtggagc tggcagacca agccttgcgt
     1501 agcttttcct atcatcagca ttcccccctc ataaaggaag tcatctgcct ttgttcaaag
     1561 atctggaaat ctgcacaggc tagtccacta ctccagggag agagccagaa ggtgtttctc
     1621 catatgctgt ctcacccatt gccacaggtg aaggtggaga cttaccagtg ctgcctggag
     1681 attgtgaagg agtgtttagg tgtccataat gtcactaaac ctgtgtcttc actgtgtagt
     1741 ggaattcatt ttctgcttca tccaaaagtt ctctatgaaa tctctgcatt tggtattcaa
     1801 gaatccaaaa atgaggtgaa tgctgctgcc aaggctgttc tcctgtatct gcttcaagga
     1861 cgatttatga tgacagctct gacctggaac aagtttatcg agtctctctg tcctgtcatt
     1921 ccagtgctac agggctatgc tgatacagaa gaccctttag gcaactgcat tctccttcta
     1981 agcaaagtga gttctgagac aggagaaggc attctcccct gcactacccg gctgaagtct
     2041 gtgctacgac ttttgctagt gaaaaaacct tcggttcgct cactagcatt aaaactttta
     2101 gcatttcatc ttaccggtga agaaggagct gatacaaagc gcccattcgt agatgctaga
     2161 gttctttcca gagttactaa tctgtttatt gtgaaaaaac ctattgatct taagttggat
     2221 gacagaagag aactagttat taagttggag actgttaaaa aggtgtatga aatcttcacc
     2281 tcagatgatg ttgatcttgt tttaagaaag tcagcagcag aacaactagc tgtgataatg
     2341 caagatatta aaatgcatac tgtggtgaaa aagttgtgct taattgagaa gattattgga
     2401 tacctaaatg aattcgtggg tcaagatggc aaggttatag aatgcttgat tcggccatgt
     2461 ctcacactcc tgaggaaggt tgtgtgtgct gacctggtta tccgtgcctc tttgtcacag
     2521 caggcctctc tcttgaccct cttactcaga gtttccttga tatttcatga agactgtgct
     2581 gtggtggctg aagtcggggc attgttttgt cttctgttgt tcgatgaagt atcaagaatg
     2641 gatatgtggt ctgataattc ttctaataaa ccttctttgt catcagtctt cagtttgcct
     2701 gtttcagtct ttagaaggta tcacctacca gtttatgtga atggccacca cgctgtgagt
     2761 ccttactcaa tagttttgcc attatctact gaatgtttgg ccctcaagcc tgtgtcagat
     2821 atgctgagaa tagcttggaa cctggcatgg tatcatggga gtgataatct attgaaacaa
     2881 acgacctctg aaactaaaat tcaggaattt tcagatacac tgcagctgtc cacagaagat
     2941 atccttacac tgaagatcac atacacggat agtgggctga aggactgcct tcagtccatt
     3001 gttcaggctg gaggccacag ggatgtgagg gctgctatta ccaggatgag tttttatctt
     3061 ttgaacgaca aactgtcttt gaaggatgat attggtccat gtgggtttac tttaaagtcc
     3121 ttggcctggc acactgtgct gaacaggttt ttacaagtac ttcctgcttg cactgaagat
     3181 gaaaaactgc taatagatat catacatttt ttgaataagt taataaagga acaaagaaaa
     3241 aatccatcag tagaactttt aaactggatt ctagaattac ttcttagaca taatccaaac
     3301 ccactattag acctgctggt tctgacagag tcacatacac gagaagtaac agatgaaatc
     3361 cggactgctg tcagacagca actccagaaa gaattgatca ctcttcttaa ttccttattg
     3421 ctggtttgca tgacagtttc tgacaggaaa tgcctggaac tattttatgt tttccaaaca
     3481 cagctgtctc tgaagctact ccagtgcctc agagtcacag atgctcccca tttctatggc
     3541 ttgccttcct tggagaggac cttagcaggg atggctcacc tcactgcctc ccctgggtgg
     3601 agtgcacatt ctcctctctc aaagccactt gagatttgtg ggaagtactt gtcaggtctc
     3661 ctggaggtaa ttacttcttt ttatgtggaa aggggaggaa acgctatgtc cttcatgggg
     3721 aaaggtgtga cgaagagcac agttctttgc ttacttcatt tatcccacga gatgatagtc
     3781 caggcaccaa actcggagtg gatgccactt tggttcttgc ctttgggtag tcacagtgaa
     3841 gaaaacgtcc cttctcagca aggattggcc tggctgattc ccttatgggt tgatcgagac
     3901 ccagaggtga gattcacttc actggggttg ggatcagcac tgactactat ggaagctggc
     3961 tgtgtggccc tggcaaacag ttgtcagaat atttctggtg ggctctgggg aactgtggtg
     4021 aacattcttc tggatcagtc agaatgcagt atggtgcggc gggaggctgc atttatactt
     4081 cagaatctcc ttgtaattcc aatgccttca aaggttataa aggattatac ttggcagggc
     4141 ccctgtgtcc atgatgaaga ttctggcctg tcactttcag gaaaacctgc actacaggcc
     4201 cttttgtatc actgccgttt ctatgaacat ttgactcaca tggtgaaaca ttgttacgtt
     4261 ggaagatata tgtttgattt taatatttct gcttttactg aaacttcaga atataatgat
     4321 ttaaatggtt tagatgactc attcaagttc tggagggccc cctctgggac atctactcag
     4381 gatcatgagc caagttctct ttctacctca gaaacaatgg tggcggcttc ggtggtcagt
     4441 gctgagattc agcccctgct gccatcaaca cttcttcctg aaccagcagc ccttgaccag
     4501 tttgtgacac aaggtcaacc tgaagtcaga cctgtgcgac cgcgtgactc atcgccgtct
     4561 gcttccctgc acaggcagtg tgtgtttgtt actccgtctc tgctgtcagc agtgtgtagc
     4621 ctcttagaca acctcttggc agttactcca agagatgctg caaatgcttt tcaacaagct
     4681 catctcatag aactcctctg tagcactatg gatgcctccc tcctagaaat gtgcgtccag
     4741 gaactcaaga ccccactgtc tttatcatct gctgttgaac atactcaggc tcagacttcc
     4801 ttttttttgg agtacctatc ctctttgttc cagcttttga agtcctgtct gttggtagat
     4861 cctaaacttg tgacacaaga tgagctcttg aaacctctta tcactaatgt catccgagtt
     4921 ctcattgtgt gtaccaaaga tgtattggat gtacagttag tgttggcttt tcaccgcaca
     4981 tggacacatt tatttgacct tctggccaca ctactgagga aggctggtgc tgtctccctt
     5041 gttcctctta cctcagctct tgccaagcac tgggaggcag tgactgatac actgtgcaga
     5101 tgtgtgggcc tctcagtcaa gtgtcctgcc cttagtattg ccagcctcca gttcctgtct
     5161 gttctcttgg ctgaggaaga aaagagacgt gtccaggaca aggataaaac aaatgcatgt
     5221 cagaccccaa cagtggcctt ccttcttgat ggaactcagg gaagccttag atcttcagag
     5281 cgacttaatg aaacaattct tcagtgctat gaaggaatct cctccaaaga cgtcctgaaa
     5341 agagttgctg caaatgctct gatgtcactt ctggctgtca gcagaagagc gcagaggcat
     5401 gcgttgaaat ctgatctcat agaaaactgt gtggagcaga tgaagcacat caatgcacaa
     5461 ctgaacctag atgtgctgag gcctgggaaa gcagcactaa aaaaaaagga ggatggcatc
     5521 attaaagagt taagcattac cctgcagctc ctaagaaact gcctttatca aaatgaagaa
     5581 tgtaaagtgg cagcttttga agcacatctt gtgcctgtcc tgcactctct ctggccttgg
     5641 cttttgatgg aagattcatt gatgcaaatt gccttgcagt tgctttgtgt ctatactgca
     5701 aattttccaa ctggctgtag ttccctttgt tggtcaaatt atggacagta tattcaaacc
     5761 gcacacagag gcacccccag cagctccctg atactgtgtg ccctgaaact ggcttctcag
     5821 gtgcctgcag agaacacccc cattcagcag gcggttttta tgtttctttc aaacctggct
     5881 ttatctcatg actgcaaggg agtaattcag aagagcaact ttctacagca cttcctgtcc
     5941 ctaacattgc ctaaaggagg aaatcaacat ctcagcaatg tgaccattct atggttgaag
     6001 ttgctcctga atatgtcgtt tggagaagat ggacagcaaa tgatcctgag actggacggc
     6061 tgcttagact tactcatcga gatgagcaag tacacacaca agagcagccc tcacgtgcct
     6121 ctgctgatct ttcataacat ttgctgcagt cctgctaata agcctaaaat tctggctaat
     6181 gaaaaggttg ttactcttct ggctacctgc ttagaaagtg agaatcaaaa tgcccagagg
     6241 attggagcgg cttcactttg ggctctaaca tacaattacc agaaggcaaa agcaactttg
     6301 aaaaatccat caattaaaag aaaaatagat gaagcatatt ccatagcaaa gagaactttc
     6361 tcaaactcag aagaagaccc tctaaattcc tactatttga aatgccttga gaatcttgta
     6421 caactgctta actgttcctg acccatgaga taccctactc caaacctgac cgccatccac
     6481 aggagatctg gatcaggggc cactttgtat agcagctgca gctttgtata gcagctgccc
     6541 ctgaatgatg ctaactctgc agtatgagtg cctgcctccc tgtgaggcag cagccgccac
     6601 actgaaagga gtagctctgg tgacttctca ggctgttcgt tcctggcagt cttccagaag
     6661 tgaagacttg ctggcctaag atgctgcaaa gacagaattc tggcaatata aacatttttt
     6721 acacttttct atgcaatatg ttttgtaaaa tgtctattta atagttattt aataaataat
     6781 atttttagaa actata
//
