LOCUS       XM_039096616            7289 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus rotatin (Rttn), transcript variant X2,
            mRNA.
ACCESSION   XM_039096616
VERSION     XM_039096616.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051353.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039096616.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7289
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..7289
                     /gene="Rttn"
                     /note="rotatin; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 1 mRNA, 6 ESTs, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 13 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:291377"
                     /db_xref="RGD:1306706"
     CDS             290..6934
                     /gene="Rttn"
                     /codon_start=1
                     /product="rotatin isoform X2"
                     /protein_id="XP_038952544.1"
                     /db_xref="GeneID:291377"
                     /db_xref="RGD:1306706"
                     /translation="MVLAGLIRKLGHQLTEIRERALKSILCKIEHNLICCADLIQERL
                     LFLHLLEWFNFPSVPMKEEVLNLLSRLVKYPPAVQHLIDLGAVEFLSKLRPNVEPAIQ
                     AEIDGILDGLFILPSEVPALRSATYQPDQNELSQQPEVLTGYFPQDKSNLQQMEVPPG
                     PVGNPTVKWLRFSVFPWLPLTTTDRHVLSSNESSLRSSNHTLIWNTCELLKDVIMQDF
                     PAEIFLQRPKIVQGLLCLVKLAFGGDGKHRLALQSVSCLQQLCTSLRNRLNFYRDPNL
                     FSNKQDTISQNSSLSYCHEARGPYHSPNPSPGSSSSRPSVVGRTGQRPRGDGQDWDAV
                     SSSGSSSHAHVNSRLSVRSPLDVAHADLPELETEDALELHFQQLSLPQFCISTLDAAV
                     PLLRTGSREMVIRVLELLGEDLLLIGQAISSEIWDDNSLFAIDVKEKLLQVLGSLGET
                     MCYRKTSFSLEQAEAILVHHRMAFVSISLFTVRLLQILLPVEKASEFLPESMSAALFF
                     VSLDMPISLEYPEIHDTVVAYLEQLDSENYSIYKRTAEAVYSIECTCNFLSDVGKEGE
                     KNLLELVELADQALRSFSYHQHSPLIKEVICLCSKIWKSAQASPLLQGESQKVFLHML
                     SHPLPQVKVETYQCCLEIVKECLGVHNVTKPVSSLCSGIHFLLHPKVLYEISAFGIQE
                     SKNEVNAAAKAVLLYLLQGRFMMTALTWNKFIESLCPVIPVLQGYADTEDPLGNCILL
                     LSKVSSETGEGILPCTTRLKSVLRLLLVKKPSVRSLALKLLAFHLTGEEGADTKRPFV
                     DARVLSRVTNLFIVKKPIDLKLDDRRELVIKLETVKKVYEIFTSDDVDLVLRKSAAEQ
                     LAVIMQDIKMHTVVKKLCLIEKIIGYLNEFVGQDGKVIECLIRPCLTLLRKVVCADLV
                     IRASLSQQASLLTLLLRVSLIFHEDCAVVAEVGALFCLLLFDEVSRMDMWSDNSSNKP
                     SLSSVFSLPVSVFRRYHLPVYVNGHHAVSPYSIVLPLSTECLALKPVSDMLRIAWNLA
                     WYHGSDNLLKQTTSETKIQEFSDTLQLSTEDILTLKITYTDSGLKDCLQSIVQAGGHR
                     DVRAAITRMSFYLLNDKLSLKDDIGPCGFTLKSLAWHTVLNRFLQVLPACTEDEKLLI
                     DIIHFLNKLIKEQRKNPSVELLNWILELLLRHNPNPLLDLLVLTESHTREVTDEIRTA
                     VRQQLQKELITLLNSLLLVCMTVSDRKCLELFYVFQTQLSLKLLQCLRVTDAPHFYGL
                     PSLERTLAGMAHLTASPGWSAHSPLSKPLEICGKYLSGLLEVITSFYVERGGNAMSFM
                     GKGVTKSTVLCLLHLSHEMIVQAPNSEWMPLWFLPLGSHSEENVPSQQGLAWLIPLWV
                     DRDPEVRFTSLGLGSALTTMEAGCVALANSCQNISGGLWGTVVNILLDQSECSMVRRE
                     AAFILQNLLVIPMPSKVIKDYTWQGPCVHDEDSGLSLSGKPALQALLYHCRFYEHLTH
                     MVKHCYVGRYMFDFNISAFTETSEYNDLNGLDDSFKFWRAPSGTSTQDHEPSSLSTSE
                     TMVAASVVSAEIQPLLPSTLLPEPAALDQFVTQGQPEVRPVRPRDSSPSASLHRQCVF
                     VTPSLLSAVCSLLDNLLAVTPRDAANAFQQAHLIELLCSTMDASLLEMCVQELKTPLS
                     LSSAVEHTQAQLLKSCLLVDPKLVTQDELLKPLITNVIRVLIVCTKDVLDVQLVLAFH
                     RTWTHLFDLLATLLRKAGAVSLVPLTSALAKHWEAVTDTLCRCVGLSVKCPALSIASL
                     QFLSVLLAEEEKRRVQDKDKTNACQTPTVAFLLDGTQGSLRSSERLNETILQCYEGIS
                     SKDVLKRVAANALMSLLAVSRRAQRHALKSDLIENCVEQMKHINAQLNLDVLRPGKAA
                     LKKKEDGIIKELSITLQLLRNCLYQNEECKVAAFEAHLVPVLHSLWPWLLMEDSLMQI
                     ALQLLCVYTANFPTGCSSLCWSNYGQYIQTAHRGTPSSSLILCALKLASQVPAENTPI
                     QQAVFMFLSNLALSHDCKGVIQKSNFLQHFLSLTLPKGGNQHLSNVTILWLKLLLNMS
                     FGEDGQQMILRLDGCLDLLIEMSKYTHKSSPHVPLLIFHNICCSPANKPKILANEKVV
                     TLLATCLESENQNAQRIGAASLWALTYNYQKAKATLKNPSIKRKIDEAYSIAKRTFSN
                     SEEDPLNSYYLKCLENLVQLLNCS"
ORIGIN      
        1 tggacggaag agggtgctac ctcttcttga ctcccttata ccttaggctt cttaggaccg
       61 aggcagaggt atacgtaatc agtcgtaata acaaagagat atcgtaaact tgtgtggtga
      121 cagaagcatt gggaactttt catttactgc tctctactca aggggtggct agcgtagaca
      181 tcgtggaacc tctgttcctt tcagacgagt ttccggagga tattaattat gaacgaactc
      241 tgtggcgcga ccgtttaatt ctccggcggc gacagattgt ggtggagaga tggttctggc
      301 ggggctcatc aggaagctcg gccatcagct gacagagatc agggaacgcg ccctcaaaag
      361 tatcctgtgc aagatcgagc acaacttgat ctgctgtgct gacttgattc aggaaaggtt
      421 gctttttctc catttgcttg aatggttcaa tttcccgtcc gtcccaatga aagaggaggt
      481 tctgaacttg ttaagcagat tggttaagta tcctccagct gtccaacact tgattgacct
      541 tggtgcagta gagttcttat ctaagctccg tccaaatgtg gagccagcaa ttcaggctga
      601 gattgatggc attctcgatg gacttttcat tcttccttca gaagttcctg cactgcgttc
      661 tgccacttac caacctgatc aaaatgaatt gtcacaacaa cctgaagttt taacaggcta
      721 ttttccccaa gacaaaagta atctccagca gatggaagtc ccaccagggc cagtgggaaa
      781 cccaactgtg aagtggctga ggttctctgt gtttccttgg ctacccctga ccacaacaga
      841 cagacatgtt ctctcctcca atgaaagctc cttgagaagt agtaaccaca ctctgatctg
      901 gaacacctgt gagcttctga aggacgtgat catgcaagac tttcctgcgg agatttttct
      961 tcagaggcct aagattgttc agggcctttt gtgtctggtg aagctggcct ttggaggaga
     1021 tgggaagcat cgtctcgcct tacagtcagt gtcctgtttg cagcagctgt gcacaagctt
     1081 aagaaacaga ctcaactttt acagagatcc caaccttttc tcgaataaac aagacacaat
     1141 ctcccagaat tcttctttgt cttactgtca tgaagcaaga ggtccttacc attccccaaa
     1201 cccgtcccca ggaagcagta gctctcggcc ttccgtggtt gggcgtacag gccagcgacc
     1261 ccgaggagat ggccaggact gggatgcagt gtcttccagc gggagcagca gtcacgcaca
     1321 tgtgaactct aggctgtctg tgcgttctcc cttggatgtg gcgcatgcag atctgccgga
     1381 gctggaaaca gaggacgcat tggagctgca cttccagcag cttagtcttc ctcagttctg
     1441 catctccacc ctggacgcag cagtccctct gctgaggaca ggtagcagag aaatggtaat
     1501 aagagttttg gaactgcttg gagaggacct gttgctcatt ggacaagcaa tttcatctga
     1561 aatctgggat gataacagcc tttttgctat agatgtgaaa gagaaactgc tccaagtgtt
     1621 ggggtccctt ggagaaacta tgtgctaccg aaagaccagt tttagcttgg agcaagcaga
     1681 ggctatacta gtgcaccaca ggatggcctt tgtcagcatc tcactgttca ccgttcgact
     1741 gttacaaatt cttctccctg ttgaaaaggc tagtgagttt ttgccagagt ccatgtcagc
     1801 agcattattt tttgtctcgt tggacatgcc tatttctttg gaatatccag agattcatga
     1861 cactgttgtg gcttatttgg aacagctgga ttctgaaaat tacagcattt ataagcgaac
     1921 tgcagaggct gtttattcaa ttgaatgtac ctgtaacttc ctatctgatg tggggaaaga
     1981 gggagaaaag aatctcctag aattagtgga gctggcagac caagccttgc gtagcttttc
     2041 ctatcatcag cattcccccc tcataaagga agtcatctgc ctttgttcaa agatctggaa
     2101 atctgcacag gctagtccac tactccaggg agagagccag aaggtgtttc tccatatgct
     2161 gtctcaccca ttgccacagg tgaaggtgga gacttaccag tgctgcctgg agattgtgaa
     2221 ggagtgttta ggtgtccata atgtcactaa acctgtgtct tcactgtgta gtggaattca
     2281 ttttctgctt catccaaaag ttctctatga aatctctgca tttggtattc aagaatccaa
     2341 aaatgaggtg aatgctgctg ccaaggctgt tctcctgtat ctgcttcaag gacgatttat
     2401 gatgacagct ctgacctgga acaagtttat cgagtctctc tgtcctgtca ttccagtgct
     2461 acagggctat gctgatacag aagacccttt aggcaactgc attctccttc taagcaaagt
     2521 gagttctgag acaggagaag gcattctccc ctgcactacc cggctgaagt ctgtgctacg
     2581 acttttgcta gtgaaaaaac cttcggttcg ctcactagca ttaaaacttt tagcatttca
     2641 tcttaccggt gaagaaggag ctgatacaaa gcgcccattc gtagatgcta gagttctttc
     2701 cagagttact aatctgttta ttgtgaaaaa acctattgat cttaagttgg atgacagaag
     2761 agaactagtt attaagttgg agactgttaa aaaggtgtat gaaatcttca cctcagatga
     2821 tgttgatctt gttttaagaa agtcagcagc agaacaacta gctgtgataa tgcaagatat
     2881 taaaatgcat actgtggtga aaaagttgtg cttaattgag aagattattg gatacctaaa
     2941 tgaattcgtg ggtcaagatg gcaaggttat agaatgcttg attcggccat gtctcacact
     3001 cctgaggaag gttgtgtgtg ctgacctggt tatccgtgcc tctttgtcac agcaggcctc
     3061 tctcttgacc ctcttactca gagtttcctt gatatttcat gaagactgtg ctgtggtggc
     3121 tgaagtcggg gcattgtttt gtcttctgtt gttcgatgaa gtatcaagaa tggatatgtg
     3181 gtctgataat tcttctaata aaccttcttt gtcatcagtc ttcagtttgc ctgtttcagt
     3241 ctttagaagg tatcacctac cagtttatgt gaatggccac cacgctgtga gtccttactc
     3301 aatagttttg ccattatcta ctgaatgttt ggccctcaag cctgtgtcag atatgctgag
     3361 aatagcttgg aacctggcat ggtatcatgg gagtgataat ctattgaaac aaacgacctc
     3421 tgaaactaaa attcaggaat tttcagatac actgcagctg tccacagaag atatccttac
     3481 actgaagatc acatacacgg atagtgggct gaaggactgc cttcagtcca ttgttcaggc
     3541 tggaggccac agggatgtga gggctgctat taccaggatg agtttttatc ttttgaacga
     3601 caaactgtct ttgaaggatg atattggtcc atgtgggttt actttaaagt ccttggcctg
     3661 gcacactgtg ctgaacaggt ttttacaagt acttcctgct tgcactgaag atgaaaaact
     3721 gctaatagat atcatacatt ttttgaataa gttaataaag gaacaaagaa aaaatccatc
     3781 agtagaactt ttaaactgga ttctagaatt acttcttaga cataatccaa acccactatt
     3841 agacctgctg gttctgacag agtcacatac acgagaagta acagatgaaa tccggactgc
     3901 tgtcagacag caactccaga aagaattgat cactcttctt aattccttat tgctggtttg
     3961 catgacagtt tctgacagga aatgcctgga actattttat gttttccaaa cacagctgtc
     4021 tctgaagcta ctccagtgcc tcagagtcac agatgctccc catttctatg gcttgccttc
     4081 cttggagagg accttagcag ggatggctca cctcactgcc tcccctgggt ggagtgcaca
     4141 ttctcctctc tcaaagccac ttgagatttg tgggaagtac ttgtcaggtc tcctggaggt
     4201 aattacttct ttttatgtgg aaaggggagg aaacgctatg tccttcatgg ggaaaggtgt
     4261 gacgaagagc acagttcttt gcttacttca tttatcccac gagatgatag tccaggcacc
     4321 aaactcggag tggatgccac tttggttctt gcctttgggt agtcacagtg aagaaaacgt
     4381 cccttctcag caaggattgg cctggctgat tcccttatgg gttgatcgag acccagaggt
     4441 gagattcact tcactggggt tgggatcagc actgactact atggaagctg gctgtgtggc
     4501 cctggcaaac agttgtcaga atatttctgg tgggctctgg ggaactgtgg tgaacattct
     4561 tctggatcag tcagaatgca gtatggtgcg gcgggaggct gcatttatac ttcagaatct
     4621 ccttgtaatt ccaatgcctt caaaggttat aaaggattat acttggcagg gcccctgtgt
     4681 ccatgatgaa gattctggcc tgtcactttc aggaaaacct gcactacagg cccttttgta
     4741 tcactgccgt ttctatgaac atttgactca catggtgaaa cattgttacg ttggaagata
     4801 tatgtttgat tttaatattt ctgcttttac tgaaacttca gaatataatg atttaaatgg
     4861 tttagatgac tcattcaagt tctggagggc cccctctggg acatctactc aggatcatga
     4921 gccaagttct ctttctacct cagaaacaat ggtggcggct tcggtggtca gtgctgagat
     4981 tcagcccctg ctgccatcaa cacttcttcc tgaaccagca gcccttgacc agtttgtgac
     5041 acaaggtcaa cctgaagtca gacctgtgcg accgcgtgac tcatcgccgt ctgcttccct
     5101 gcacaggcag tgtgtgtttg ttactccgtc tctgctgtca gcagtgtgta gcctcttaga
     5161 caacctcttg gcagttactc caagagatgc tgcaaatgct tttcaacaag ctcatctcat
     5221 agaactcctc tgtagcacta tggatgcctc cctcctagaa atgtgcgtcc aggaactcaa
     5281 gaccccactg tctttatcat ctgctgttga acatactcag gctcagcttt tgaagtcctg
     5341 tctgttggta gatcctaaac ttgtgacaca agatgagctc ttgaaacctc ttatcactaa
     5401 tgtcatccga gttctcattg tgtgtaccaa agatgtattg gatgtacagt tagtgttggc
     5461 ttttcaccgc acatggacac atttatttga ccttctggcc acactactga ggaaggctgg
     5521 tgctgtctcc cttgttcctc ttacctcagc tcttgccaag cactgggagg cagtgactga
     5581 tacactgtgc agatgtgtgg gcctctcagt caagtgtcct gcccttagta ttgccagcct
     5641 ccagttcctg tctgttctct tggctgagga agaaaagaga cgtgtccagg acaaggataa
     5701 aacaaatgca tgtcagaccc caacagtggc cttccttctt gatggaactc agggaagcct
     5761 tagatcttca gagcgactta atgaaacaat tcttcagtgc tatgaaggaa tctcctccaa
     5821 agacgtcctg aaaagagttg ctgcaaatgc tctgatgtca cttctggctg tcagcagaag
     5881 agcgcagagg catgcgttga aatctgatct catagaaaac tgtgtggagc agatgaagca
     5941 catcaatgca caactgaacc tagatgtgct gaggcctggg aaagcagcac taaaaaaaaa
     6001 ggaggatggc atcattaaag agttaagcat taccctgcag ctcctaagaa actgccttta
     6061 tcaaaatgaa gaatgtaaag tggcagcttt tgaagcacat cttgtgcctg tcctgcactc
     6121 tctctggcct tggcttttga tggaagattc attgatgcaa attgccttgc agttgctttg
     6181 tgtctatact gcaaattttc caactggctg tagttccctt tgttggtcaa attatggaca
     6241 gtatattcaa accgcacaca gaggcacccc cagcagctcc ctgatactgt gtgccctgaa
     6301 actggcttct caggtgcctg cagagaacac ccccattcag caggcggttt ttatgtttct
     6361 ttcaaacctg gctttatctc atgactgcaa gggagtaatt cagaagagca actttctaca
     6421 gcacttcctg tccctaacat tgcctaaagg aggaaatcaa catctcagca atgtgaccat
     6481 tctatggttg aagttgctcc tgaatatgtc gtttggagaa gatggacagc aaatgatcct
     6541 gagactggac ggctgcttag acttactcat cgagatgagc aagtacacac acaagagcag
     6601 ccctcacgtg cctctgctga tctttcataa catttgctgc agtcctgcta ataagcctaa
     6661 aattctggct aatgaaaagg ttgttactct tctggctacc tgcttagaaa gtgagaatca
     6721 aaatgcccag aggattggag cggcttcact ttgggctcta acatacaatt accagaaggc
     6781 aaaagcaact ttgaaaaatc catcaattaa aagaaaaata gatgaagcat attccatagc
     6841 aaagagaact ttctcaaact cagaagaaga ccctctaaat tcctactatt tgaaatgcct
     6901 tgagaatctt gtacaactgc ttaactgttc ctgacccatg agatacccta ctccaaacct
     6961 gaccgccatc cacaggagat ctggatcagg ggccactttg tatagcagct gcagctttgt
     7021 atagcagctg cccctgaatg atgctaactc tgcagtatga gtgcctgcct ccctgtgagg
     7081 cagcagccgc cacactgaaa ggagtagctc tggtgacttc tcaggctgtt cgttcctggc
     7141 agtcttccag aagtgaagac ttgctggcct aagatgctgc aaagacagaa ttctggcaat
     7201 ataaacattt tttacacttt tctatgcaat atgttttgta aaatgtctat ttaatagtta
     7261 tttaataaat aatattttta gaaactata
//
