LOCUS       NM_001170436            7078 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus rotatin (Rttn), mRNA.
ACCESSION   NM_001170436 XM_001063569 XM_214524
VERSION     NM_001170436.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 7078)
  AUTHORS   Kheradmand Kia,S., Verbeek,E., Engelen,E., Schot,R., Poot,R.A., de
            Coo,I.F., Lequin,M.H., Poulton,C.J., Pourfarzad,F., Grosveld,F.G.,
            Brehm,A., de Wit,M.C., Oegema,R., Dobyns,W.B., Verheijen,F.W. and
            Mancini,G.M.
  TITLE     RTTN mutations link primary cilia function to organization of the
            human cerebral cortex
  JOURNAL   Am J Hum Genet 91 (3), 533-540 (2012)
   PUBMED   22939636
REFERENCE   2  (bases 1 to 7078)
  AUTHORS   Faisst,A.M., Alvarez-Bolado,G., Treichel,D. and Gruss,P.
  TITLE     Rotatin is a novel gene required for axial rotation and left-right
            specification in mouse embryos
  JOURNAL   Mech Dev 113 (1), 15-28 (2002)
   PUBMED   11900971
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000018.1 and FN802245.1.
            
            On Sep 27, 2014 this sequence version replaced NM_001170436.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760383, SAMEA5760389
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-68                JAXUCZ010000018.1  84495964-84496031
            69-256              JAXUCZ010000018.1  84496327-84496514
            257-434             JAXUCZ010000018.1  84497459-84497636
            435-524             JAXUCZ010000018.1  84498393-84498482
            525-615             JAXUCZ010000018.1  84499660-84499750
            616-730             JAXUCZ010000018.1  84501672-84501786
            731-881             JAXUCZ010000018.1  84503595-84503745
            882-1047            JAXUCZ010000018.1  84507669-84507834
            1048-1229           JAXUCZ010000018.1  84509689-84509870
            1230-1345           JAXUCZ010000018.1  84512511-84512626
            1346-1516           JAXUCZ010000018.1  84526730-84526900
            1517-1576           JAXUCZ010000018.1  84536670-84536729
            1577-2212           FN802245.1         1-636
            2213-2352           JAXUCZ010000018.1  84544372-84544511
            2353-2524           JAXUCZ010000018.1  84547110-84547281
            2525-2624           JAXUCZ010000018.1  84548695-84548794
            2625-2713           JAXUCZ010000018.1  84553211-84553299
            2714-2831           JAXUCZ010000018.1  84554258-84554375
            2832-2928           JAXUCZ010000018.1  84558839-84558935
            2929-2997           JAXUCZ010000018.1  84559505-84559573
            2998-3186           JAXUCZ010000018.1  84563611-84563799
            3187-3426           JAXUCZ010000018.1  84564303-84564542
            3427-3571           JAXUCZ010000018.1  84570640-84570784
            3572-3726           JAXUCZ010000018.1  84580114-84580268
            3727-3946           JAXUCZ010000018.1  84582441-84582660
            3947-4075           JAXUCZ010000018.1  84588731-84588859
            4076-4186           JAXUCZ010000018.1  84589516-84589626
            4187-4345           JAXUCZ010000018.1  84592936-84593094
            4346-4417           JAXUCZ010000018.1  84594673-84594744
            4418-4607           JAXUCZ010000018.1  84613218-84613407
            4608-4699           JAXUCZ010000018.1  84614947-84615038
            4700-4793           JAXUCZ010000018.1  84621559-84621652
            4794-4808           JAXUCZ010000018.1  84623061-84623075
            4809-4986           JAXUCZ010000018.1  84628343-84628520
            4987-5077           JAXUCZ010000018.1  84630014-84630104
            5078-5231           JAXUCZ010000018.1  84632041-84632194
            5232-5369           JAXUCZ010000018.1  84636648-84636785
            5370-5587           JAXUCZ010000018.1  84637832-84638049
            5588-5693           JAXUCZ010000018.1  84643482-84643587
            5694-5791           JAXUCZ010000018.1  84644618-84644715
            5792-5869           JAXUCZ010000018.1  84646592-84646669
            5870-5996           JAXUCZ010000018.1  84656122-84656248
            5997-6196           JAXUCZ010000018.1  84658168-84658367
            6197-6464           JAXUCZ010000018.1  84663148-84663415
            6465-6568           JAXUCZ010000018.1  84670635-84670738
            6569-6638           JAXUCZ010000018.1  84671549-84671618
            6639-7078           JAXUCZ010000018.1  84672640-84673079
FEATURES             Location/Qualifiers
     source          1..7078
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18q13"
     gene            1..7078
                     /gene="Rttn"
                     /note="rotatin"
                     /db_xref="GeneID:291377"
                     /db_xref="RGD:1306706"
     exon            1..68
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     CDS             38..6724
                     /gene="Rttn"
                     /codon_start=1
                     /product="rotatin"
                     /protein_id="NP_001163907.2"
                     /db_xref="GeneID:291377"
                     /db_xref="RGD:1306706"
                     /translation="MVLAGLIRKLGHQLTEIRERALKSILCKIEHNLICCADLIQERL
                     LFLHLLEWFNFPSVPMKEEVLNLLSRLVKYPPAVQHLIDLGAVEFLSKLRPNVEPAIQ
                     AEIDGILDGLFILPSEVPALRSATYQPDQNELSQQPEVLTGYFPQDKSNLQQMEVPPG
                     PVGNPTVKWLRFSVFPWLPLTTTDRHVLSSNESSLRSSNHTLIWNTCELLKDVIMQDF
                     PAEIFLQRPKIVQGLLCLVKLAFGGDGKHRLALQSVSCLQQLCTSLRNRLNFYRDPNL
                     FSNKQDTISQNSSLSYCHEARGPYHSPNPSPGSSSSRPSVVGRTGQRPRGDGQDWDAV
                     SSSGSSSHAHVNSRLSVRSPLDVAHADLPELETEDALELHFQQLSLPQFCISTLDAAV
                     PLLRTGSREMVIRVLELLGEDLLLIGQAISSEIWDDNSLFAIDVKEKLLQVLGSLGET
                     MCYRKTSFSLEQAEAILVHHRMAFVSISLFTVRLLQILLPVEKASEFLPESMSAALFF
                     VSLDMPISLEYPEIHDTVVAYLEQLDSENYSIYKRTAEAVYSIECTCNFLSDVGKEGE
                     KNLLELVELADQALRSFSYHQHSPLIKEVICLCSKIWKSAQASPLLQGESQKVFLHML
                     SHPLPQVKVETYQCCLEIVKECLGVHNVTKPVSSLCSGIHFLLHPKVLYEISAFGIQE
                     SKNEVNAAAKAVLLYLLQGRFMMTALTWNKFIESLCPVIPVLQGYADTEDPLGNCILL
                     LSKVSSETGEGILPCTTRLKSVLRLLLVKKPSVRSLALKLLAFHLTGEEGADTKRPFV
                     DARVLSRVTNLFIVKKPIDLKLDDRRELVIKLETVKKVYEIFTSDDVDLVLRKSAAEQ
                     LAVIMQDIKMHTVVKKLCLIEKIIGYLNEFVGQDGKVIECLIRPCLTLLRKVVCADLV
                     IRASLSQQASLLTLLLRVSLIFHEDCAVVAEVGALFCLLLFDEVSRMDMWSDNSSNKP
                     SLSSVFSLPVSVFRRYHLPVYVNGHHAVSPYSIVLPLSTECLALKPVSDMLRIAWNLA
                     WYHGSDNLLKQTTSETKIQEFSDTLQLSTEDILTLKITYTDSGLKDCLQSIVQAGGHR
                     DVRAAITRMSFYLLNDKLSLKDDIGPCGFTLKSLAWHTVLNRFLQVLPACTEDEKLLI
                     DIIHFLNKLIKEQRKNPSVELLNWILELLLRHNPNPLLDLLVLTESHTREVTDEIRTA
                     VRQQLQKELITLLNSLLLVCMTVSDRKCLELFYVFQTQLSLKLLQCLRVTDAPHFYGL
                     PSLERTLAGMAHLTASPGWSAHSPLSKPLEICGKYLSGLLEVITSFYVERGGNAMSFM
                     GKGVTKSTVLCLLHLSHEMIVQAPNSEWMPLWFLPLGSHSEENVPSQQGLAWLIPLWV
                     DRDPEVRFTSLGLGSALTTMEAGCVALANSCQNISGGLWGTVVNILLDQSECSMVRRE
                     AAFILQNLLVIPMPSKVIKDYTWQGPCVHDEDSGLSLSGKPALQALLYHCRFYEHLTH
                     MVKHCYVGRYMFDFNISAFTETSEYNDLNGLDDSFKFWRAPSGTSTQDHEPSSLSTSE
                     TMVAASVVSAEIQPLLPSTLLPEPAALDQFVTQGHLHSVRPVRPRDSSPSASLHRQCV
                     FVTPSLLSAVCSLLDNLLAVTPRDAANAFQQAHLIELLCSTMDASLLEMCVQELKTPL
                     SLSSAVEHTQAQTSFFLEYLSSLFQLLKSCLLVDPKLVTQDELLKPLITNVIRVLIVC
                     TKDVLDVQLVLAFHRTWTHLFDLLATLLRKAGAVSLVPLTSALAKHWEAVTDTLCRCV
                     GLSVKCPALSIASLQFLSVLLAEEEKRRVQDKDKTNACQTPTVAFLLDGTQGSLRSSE
                     RLNETILQCYEGISSKDVLKRVAANALMSLLAVSRRAQRHALKSDLIENCVEQMKHIN
                     AQLNLDVLRPGKAALKKKEDGIIKELSITLQLLRNCLYQNEECKVAAFEAHLVPVLHS
                     LWPWLLMEDSLMQIALQLLCVYTANFPTGCSSLCWSNYGQYIQTAHRGTPSSSLILCA
                     LKLASQVPAENTPIQQAVFMFLSNLALSHDCKGVIQKSNFLQHFLSLTLPKGGNQHLS
                     NVTILWLKLLLNMSFGEDGQQMILRLDGCLDLLIEMSKYTHKSSPHVPLLIFHNICCS
                     PANKPKILANEKVVTLLATCLESENQNAQRIGAASLWALTYNYQKAKATLKNPSIKRK
                     IDEAYSIAKRTFSNSEEDPLNSYYLKCLENLVQLLNCS"
     exon            69..256
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            257..434
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            435..524
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            525..615
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            616..730
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            731..881
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            882..1047
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            1048..1229
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            1230..1345
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            1346..1516
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            1517..1729
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            1730..1842
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            1843..1969
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            1970..2095
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            2096..2212
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            2213..2352
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            2353..2524
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            2525..2624
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            2625..2713
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            2714..2831
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            2832..2928
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            2929..2997
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            2998..3186
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            3187..3426
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            3427..3571
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            3572..3726
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            3727..3946
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            3947..4075
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            4076..4186
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            4187..4345
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            4346..4417
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            4418..4607
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            4608..4699
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            4700..4793
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            4794..4808
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            4809..4986
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            4987..5077
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            5078..5231
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            5232..5369
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            5370..5587
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            5588..5693
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            5694..5791
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            5792..5869
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            5870..5996
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            5997..6196
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            6197..6464
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            6465..6568
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            6569..6638
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
     exon            6639..7078
                     /gene="Rttn"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtttaattct ccggcggcga cagattgtgg tggagagatg gttctggcgg ggctcatcag
       61 gaagctcggc catcagctga cagagatcag ggaacgcgcc ctcaaaagta tcctgtgcaa
      121 gatcgagcac aacttgatct gctgtgctga cttgattcag gaaaggttgc tttttctcca
      181 tttgcttgaa tggttcaatt tcccgtccgt cccaatgaaa gaggaggttc tgaacttgtt
      241 aagcagattg gttaagtatc ctccagctgt ccaacacttg attgaccttg gtgcagtaga
      301 gttcttatct aagctccgtc caaatgtgga gccagcaatt caggctgaga ttgatggcat
      361 tctcgatgga cttttcattc ttccttcaga agttcctgca ctgcgttctg ccacttacca
      421 acctgatcaa aatgaattgt cacaacaacc tgaagtttta acaggctatt ttccccaaga
      481 caaaagtaat ctccagcaga tggaagtccc accagggcca gtgggaaacc caactgtgaa
      541 gtggctgagg ttctctgtgt ttccttggct acccctgacc acaacagaca gacatgttct
      601 ctcctccaat gaaagctcct tgagaagtag taaccacact ctgatctgga acacctgtga
      661 gcttctgaag gacgtgatca tgcaagactt tcctgcggag atttttcttc agaggcctaa
      721 gattgttcag ggccttttgt gtctggtgaa gctggccttt ggaggagatg ggaagcatcg
      781 tctcgcctta cagtcagtgt cctgtttgca gcagctgtgc acaagcttaa gaaacagact
      841 caacttttac agagatccca accttttctc gaataaacaa gacacaatct cccagaattc
      901 ttctttgtct tactgtcatg aagcaagagg tccttaccat tccccaaacc cgtccccagg
      961 aagcagtagc tctcggcctt ccgtggttgg gcgtacaggc cagcgacccc gaggagatgg
     1021 ccaggactgg gatgcagtgt cttccagcgg gagcagcagt cacgcacatg tgaactctag
     1081 gctgtctgtg cgttctccct tggatgtggc gcatgcagat ctgccggagc tggaaacaga
     1141 ggacgcattg gagctgcact tccagcagct tagtcttcct cagttctgca tctccaccct
     1201 ggacgcagca gtccctctgc tgaggacagg tagcagagaa atggtaataa gagttttgga
     1261 actgcttgga gaggacctgt tgctcattgg acaagcaatt tcatctgaaa tctgggatga
     1321 taacagcctt tttgctatag atgtgaaaga gaaactgctc caagtgttgg ggtcccttgg
     1381 agaaactatg tgctaccgaa agaccagttt tagcttggag caagcagagg ctatactagt
     1441 gcaccacagg atggcctttg tcagcatctc actgttcacc gttcgactgt tacaaattct
     1501 tctccctgtt gaaaaggcta gtgagttttt gccagagtcc atgtcagcag cattattttt
     1561 tgtctcgttg gacatgccta tttctttgga atatccagag attcatgaca ctgttgtggc
     1621 ttatttggaa cagctggatt ctgaaaatta cagcatttat aagcgaactg cagaggctgt
     1681 ttattcaatt gaatgtacct gtaacttcct atctgatgtg gggaaagagg gagaaaagaa
     1741 tctcctagaa ttagtggagc tggcagacca agccttgcgt agcttttcct atcatcagca
     1801 ttcccccctc ataaaggaag tcatctgcct ttgttcaaag atctggaaat ctgcacaggc
     1861 tagtccacta ctccagggag agagccagaa ggtgtttctc catatgctgt ctcacccatt
     1921 gccacaggtg aaggtggaga cttaccagtg ctgcctggag attgtgaagg agtgtttagg
     1981 tgtccataat gtcactaaac ctgtgtcttc actgtgtagt ggaattcatt ttctgcttca
     2041 tccaaaagtt ctctatgaaa tctctgcatt tggtattcaa gaatccaaaa atgaggtgaa
     2101 tgctgctgcc aaggctgttc tcctgtatct gcttcaagga cgatttatga tgacagctct
     2161 gacctggaac aagtttatcg agtctctctg tcctgtcatt ccagtgctac agggctatgc
     2221 tgatacagaa gaccctttag gcaactgcat tctccttcta agcaaagtga gttctgagac
     2281 aggagaaggc attctcccct gcactacccg gctgaagtct gtgctacgac ttttgctagt
     2341 gaaaaaacct tcggttcgct cactagcatt aaaactttta gcatttcatc ttaccggtga
     2401 agaaggagct gatacaaagc gcccattcgt agatgctaga gttctttcca gagttactaa
     2461 tctgtttatt gtgaaaaaac ctattgatct taagttggat gacagaagag aactagttat
     2521 taagttggag actgttaaaa aggtgtatga aatcttcacc tcagatgatg ttgatcttgt
     2581 tttaagaaag tcagcagcag aacaactagc tgtgataatg caagatatta aaatgcatac
     2641 tgtggtgaaa aagttgtgct taattgagaa gattattgga tacctaaatg aattcgtggg
     2701 tcaagatggc aaggttatag aatgcttgat tcggccatgt ctcacactcc tgaggaaggt
     2761 tgtgtgtgct gacctggtta tccgtgcctc tttgtcacag caggcctctc tcttgaccct
     2821 cttactcaga gtttccttga tatttcatga agactgtgct gtggtggctg aagtcggggc
     2881 attgttttgt cttctgttgt tcgatgaagt atcaagaatg gatatgtggt ctgataattc
     2941 ttctaataaa ccttctttgt catcagtctt cagtttgcct gtttcagtct ttagaaggta
     3001 tcacctacca gtttatgtga atggccacca cgctgtgagt ccttactcaa tagttttgcc
     3061 attatctact gaatgtttgg ccctcaagcc tgtgtcagat atgctgagaa tagcttggaa
     3121 cctggcatgg tatcatggga gtgataatct attgaaacaa acgacctctg aaactaaaat
     3181 tcaggaattt tcagatacac tgcagctgtc cacagaagat atccttacac tgaagatcac
     3241 atacacggat agtgggctga aggactgcct tcagtccatt gttcaggctg gaggccacag
     3301 ggatgtgagg gctgctatta ccaggatgag tttttatctt ttgaacgaca aactgtcttt
     3361 gaaggatgat attggtccat gtgggtttac tttaaagtcc ttggcctggc acactgtgct
     3421 gaacaggttt ttacaagtac ttcctgcttg cactgaagat gaaaaactgc taatagatat
     3481 catacatttt ttgaataagt taataaagga acaaagaaaa aatccatcag tagaactttt
     3541 aaactggatt ctagaattac ttcttagaca taatccaaac ccactattag acctgctggt
     3601 tctgacagag tcacatacac gagaagtaac agatgaaatc cggactgctg tcagacagca
     3661 actccagaaa gaattgatca ctcttcttaa ttccttattg ctggtttgca tgacagtttc
     3721 tgacaggaaa tgcctggaac tattttatgt tttccaaaca cagctgtctc tgaagctact
     3781 ccagtgcctc agagtcacag atgctcccca tttctatggc ttgccttcct tggagaggac
     3841 cttagcaggg atggctcacc tcactgcctc ccctgggtgg agtgcacatt ctcctctctc
     3901 aaagccactt gagatttgtg ggaagtactt gtcaggtctc ctggaggtaa ttacttcttt
     3961 ttatgtggaa aggggaggaa acgctatgtc cttcatgggg aaaggtgtga cgaagagcac
     4021 agttctttgc ttacttcatt tatcccacga gatgatagtc caggcaccaa actcggagtg
     4081 gatgccactt tggttcttgc ctttgggtag tcacagtgaa gaaaacgtcc cttctcagca
     4141 aggattggcc tggctgattc ccttatgggt tgatcgagac ccagaggtga gattcacttc
     4201 actggggttg ggatcagcac tgactactat ggaagctggc tgtgtggccc tggcaaacag
     4261 ttgtcagaat atttctggtg ggctctgggg aactgtggtg aacattcttc tggatcagtc
     4321 agaatgcagt atggtgcggc gggaggctgc atttatactt cagaatctcc ttgtaattcc
     4381 aatgccttca aaggttataa aggattatac ttggcagggc ccctgtgtcc atgatgaaga
     4441 ttctggcctg tcactttcag gaaaacctgc actacaggcc cttttgtatc actgccgttt
     4501 ctatgaacat ttgactcaca tggtgaaaca ttgttacgtt ggaagatata tgtttgattt
     4561 taatatttct gcttttactg aaacttcaga atataatgat ttaaatggtt tagatgactc
     4621 attcaagttc tggagggccc cctctgggac atctactcag gatcatgagc caagttctct
     4681 ttctacctca gaaacaatgg tggcggcttc ggtggtcagt gctgagattc agcccctgct
     4741 gccatcaaca cttcttcctg aaccagcagc ccttgaccag tttgtgacac aagggcacct
     4801 gcactcagtc agacctgtgc gaccgcgtga ctcatcgccg tctgcttccc tgcacaggca
     4861 gtgtgtgttt gttactccgt ctctgctgtc agcagtgtgt agcctcttag acaacctctt
     4921 ggcagttact ccaagagatg ctgcaaatgc ttttcaacaa gctcatctca tagaactcct
     4981 ctgtagcact atggatgcct ccctcctaga aatgtgcgtc caggaactca agaccccact
     5041 gtctttatca tctgctgttg aacatactca ggctcagact tccttttttt tggagtacct
     5101 atcctctttg ttccagcttt tgaagtcctg tctgttggta gatcctaaac ttgtgacaca
     5161 agatgagctc ttgaaacctc ttatcactaa tgtcatccga gttctcattg tgtgtaccaa
     5221 agatgtattg gatgtacagt tagtgttggc ttttcaccgc acatggacac atttatttga
     5281 ccttctggcc acactactga ggaaggctgg tgctgtctcc cttgttcctc ttacctcagc
     5341 tcttgccaag cactgggagg cagtgactga tacactgtgc agatgtgtgg gcctctcagt
     5401 caagtgtcct gcccttagta ttgccagcct ccagttcctg tctgttctct tggctgagga
     5461 agaaaagaga cgtgtccagg acaaggataa aacaaatgca tgtcagaccc caacagtggc
     5521 cttccttctt gatggaactc agggaagcct tagatcttca gagcgactta atgaaacaat
     5581 tcttcagtgc tatgaaggaa tctcctccaa agacgtcctg aaaagagttg ctgcaaatgc
     5641 tctgatgtca cttctggctg tcagcagaag agcgcagagg catgcgttga aatctgatct
     5701 catagaaaac tgtgtggagc agatgaagca catcaatgca caactgaacc tagatgtgct
     5761 gaggcctggg aaagcagcac taaaaaaaaa ggaggatggc atcattaaag agttaagcat
     5821 taccctgcag ctcctaagaa actgccttta tcaaaatgaa gaatgtaaag tggcagcttt
     5881 tgaagcacat cttgtgcctg tcctgcactc tctctggcct tggcttttga tggaagattc
     5941 attgatgcaa attgccttgc agttgctttg tgtctatact gcaaattttc caactggctg
     6001 tagttccctt tgttggtcaa attatggaca gtatattcaa accgcacaca gaggcacccc
     6061 cagcagctcc ctgatactgt gtgccctgaa actggcttct caggtgcctg cagagaacac
     6121 ccccattcag caggcggttt ttatgtttct ttcaaacctg gctttatctc atgactgcaa
     6181 gggagtaatt cagaagagca actttctaca gcacttcctg tccctaacat tgcctaaagg
     6241 aggaaatcaa catctcagca atgtgaccat tctatggttg aagttgctcc tgaatatgtc
     6301 gtttggagaa gatggacagc aaatgatcct gagactggac ggctgcttag acttactcat
     6361 cgagatgagc aagtacacac acaagagcag ccctcacgtg cctctgctga tctttcataa
     6421 catttgctgc agtcctgcta ataagcctaa aattctggct aatgaaaagg ttgttactct
     6481 tctggctacc tgcttagaaa gtgagaatca aaatgcccag aggattggag cggcttcact
     6541 ttgggctcta acatacaatt accagaaggc aaaagcaact ttgaaaaatc catcaattaa
     6601 aagaaaaata gatgaagcat attccatagc aaagagaact ttctcaaact cagaagaaga
     6661 ccctctaaat tcctactatt tgaaatgcct tgagaatctt gtacaactgc ttaactgttc
     6721 ctgacccatg agatacccta ctccaaacct gaccgccatc cacaggagat ctggatcagg
     6781 ggccactttg tatagcagct gcagctttgt atagcagctg cccctgaatg atgctaactc
     6841 tgcagtatga gtgcctgcct ccctgtgagg cagcagccgc cacactgaaa ggagtagctc
     6901 tggtgacttc tcaggctgtt cgttcctggc agtcttccag aagtgaagac ttgctggcct
     6961 aagatgctgc aaagacagaa ttctggcaat ataaacattt tttacacttt tctatgcaat
     7021 atgttttgta aaatgtctat ttaatagtta tttaataaat aatattttta gaaactat
//
