LOCUS       NM_181377               3309 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus reticulon 4 receptor-like 1 (Rtn4rl1), mRNA.
ACCESSION   NM_181377
VERSION     NM_181377.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3309)
  AUTHORS   Yoo,S.W., Motari,M.G. and Schnaar,R.L.
  TITLE     Agenesis of the corpus callosum in Nogo receptor deficient mice
  JOURNAL   J Comp Neurol 525 (2), 291-301 (2017)
   PUBMED   27339102
REFERENCE   2  (bases 1 to 3309)
  AUTHORS   Dickendesher,T.L., Baldwin,K.T., Mironova,Y.A., Koriyama,Y.,
            Raiker,S.J., Askew,K.L., Wood,A., Geoffroy,C.G., Zheng,B.,
            Liepmann,C.D., Katagiri,Y., Benowitz,L.I., Geller,H.M. and
            Giger,R.J.
  TITLE     NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans
  JOURNAL   Nat Neurosci 15 (5), 703-712 (2012)
   PUBMED   22406547
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3309)
  AUTHORS   Thomas,R., Favell,K., Morante-Redolat,J., Pool,M., Kent,C.,
            Wright,M., Daignault,K., Ferraro,G.B., Montcalm,S., Durocher,Y.,
            Fournier,A., Perez-Tur,J. and Barker,P.A.
  TITLE     LGI1 is a Nogo receptor 1 ligand that antagonizes myelin-based
            growth inhibition
  JOURNAL   J Neurosci 30 (19), 6607-6612 (2010)
   PUBMED   20463223
REFERENCE   4  (bases 1 to 3309)
  AUTHORS   Richard,M., Sacquet,J., Jourdan,F. and Pellier-Monnin,V.
  TITLE     Spatio-temporal expression pattern of receptors for
            myelin-associated inhibitors in the developing rat olfactory system
  JOURNAL   Brain Res 1252, 52-65 (2009)
   PUBMED   19063867
  REMARK    GeneRIF: spatio-temporal expression pattern of NgR1, NgR2 & NgR3
            mRNAs & corresponding proteins in developing olfactory system; data
            suggest, in non-pathological conditions, NgR1 & homologs may play a
            role in axon outgrowth in the olfactory system.
REFERENCE   5  (bases 1 to 3309)
  AUTHORS   Venkatesh,K., Chivatakarn,O., Lee,H., Joshi,P.S., Kantor,D.B.,
            Newman,B.A., Mage,R., Rader,C. and Giger,R.J.
  TITLE     The Nogo-66 receptor homolog NgR2 is a sialic acid-dependent
            receptor selective for myelin-associated glycoprotein
  JOURNAL   J Neurosci 25 (4), 808-822 (2005)
   PUBMED   15673660
REFERENCE   6  (bases 1 to 3309)
  AUTHORS   Pignot,V., Hein,A.E., Barske,C., Wiessner,C., Walmsley,A.R.,
            Kaupmann,K., Mayeur,H., Sommer,B., Mir,A.K. and Frentzel,S.
  TITLE     Characterization of two novel proteins, NgRH1 and NgRH2,
            structurally and biochemically homologous to the Nogo-66 receptor
  JOURNAL   J Neurochem 85 (3), 717-728 (2003)
   PUBMED   12694398
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC129084.1.
            
            On Jan 10, 2007 this sequence version replaced NM_181377.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC129084.1, AF532861.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3309
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q24"
     gene            1..3309
                     /gene="Rtn4rl1"
                     /gene_synonym="Ngrh2"
                     /note="reticulon 4 receptor-like 1"
                     /db_xref="GeneID:303311"
                     /db_xref="RGD:727812"
     exon            1..321
                     /gene="Rtn4rl1"
                     /gene_synonym="Ngrh2"
                     /inference="alignment:Splign:2.1.0"
     CDS             309..1646
                     /gene="Rtn4rl1"
                     /gene_synonym="Ngrh2"
                     /note="ngR3; nogo receptor-like 2; nogo-66
                     receptor-related protein 3; Nogo-66 receptor homolog 2"
                     /codon_start=1
                     /product="reticulon-4 receptor-like 1 precursor"
                     /protein_id="NP_852042.1"
                     /db_xref="GeneID:303311"
                     /db_xref="RGD:727812"
                     /translation="MLRKGCCVELLLLLLAGELPLSGGCPRDCVCYPSPMTVSCQAHN
                     FAAIPEGIPEDSERIFLQNNHITFLQQGHFSPAMVTLWIYSNNITFIAPNTFEGFVHL
                     EELDLGDNRQLRTLAPETFQGLVKLHALYLYKCGLSSLPAGIFGGLHSLQYLYLQDNH
                     IEYLQDDIFVDLVNLSHLFLHGNKLWSLGQGIFRGLVNLDRLLLHENQLQWVHHKAFH
                     DLHRLTTLFLFNNSLTELQGDCLAPLVALEFLRLNGNAWDCGCRARSLWEWLRRFRGS
                     SSVVPCATPELRQGQDLKSLRVEDFRNCTGPASPHQIKSHTLSTSDRAARKEHHPSHG
                     ASRDKGHPHGHLPGSRSGSKKPGKNCTSHRNRNQISKGSAGKELPELQDYAPDYQHKF
                     SFDIMPTARPKRKGKCARRTPIRAPSGVQQASSGTALGVSLLAWILGLVVSLR"
     exon            322..3286
                     /gene="Rtn4rl1"
                     /gene_synonym="Ngrh2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgcaaagtg tttggggcgg cagaatcagg ccgccggctc ggtggagcaa gccactcgcc
       61 ccggggctga gagagcgcac ggcgttggtt ggcagcgccg cggttgctag caggcgccgg
      121 tgccctgggc gccgtgcttg ggctcaccat gcccctgcgg gaccgggccg ccgggcacaa
      181 gcggattccc ggcttgcccc cgcctcgacg cgctcggatt agctgtagct ggcgcccagg
      241 gatttgaatc tggaccccag gagggagcgc gcctaggccg acctcggaac ggcggccccg
      301 cggccaacat gcttcgcaaa gggtgctgtg tggaattgct gctgttgctg ctggctggag
      361 agctacctct gagtggtggt tgtcctcgag actgtgtgtg ctacccctcg cccatgactg
      421 tcagttgcca ggcacacaac tttgccgcca tccccgaggg catcccagag gacagcgagc
      481 gcatcttcct gcagaacaat cacatcacct tcctccagca gggccacttc agccccgcca
      541 tggtcaccct ctggatctac tccaacaaca tcactttcat tgctcccaac acctttgagg
      601 gctttgtgca tctggaggag ctagaccttg gagacaaccg gcagcttcga acgctggcac
      661 ccgagacctt ccaaggcctg gtgaagcttc acgccctcta cctctacaag tgcggactga
      721 gctccctgcc tgcgggcatc tttggtggcc tgcacagcct gcagtacctc tacttgcagg
      781 acaaccatat tgagtacctc caagatgaca tctttgtgga cctggtcaac ctcagtcact
      841 tgtttctcca tggcaacaag ctatggagcc tgggccaggg catcttccgg ggcctggtga
      901 acctggaccg gttgctgctg catgagaacc agctacagtg ggtccaccac aaggctttcc
      961 atgacctcca caggctaacc accctctttc tcttcaacaa tagcctcacc gagctgcagg
     1021 gtgactgcct ggcccccctg gtggccctgg agtttcttcg cctcaatggg aatgcttggg
     1081 actgtggctg ccgggcacgg tccctgtggg aatggctgcg aaggttccgt ggctccagct
     1141 ctgttgtccc ctgcgcgact ccagagctgc ggcaaggcca ggacctgaag tcgctgaggg
     1201 ttgaggactt ccggaactgc actggaccag cgtctcctca ccagatcaag tctcacacgc
     1261 ttagcacctc tgacagggct gcccgcaagg agcaccatcc ctcccacggt gcctccaggg
     1321 acaaaggcca cccacatggc catctgcctg gctccaggtc aggttccaag aagccaggca
     1381 agaactgcac cagccacagg aaccgaaacc agatctctaa ggggagcgct gggaaagagc
     1441 ttcctgaact gcaggactat gcccccgact atcagcacaa gttcagcttt gacatcatgc
     1501 ccactgcacg acccaagagg aagggcaagt gtgcccgcag gacccccatc cgtgccccca
     1561 gtggggtgca gcaggcctcc tcaggcacgg ccctcggggt ctcactcctg gcctggatac
     1621 tggggctggt ggtatctctc cgctgaggac ccagggcacc gtcacccagc actgccacct
     1681 gtccagcaag gaacagaatc tttttttttt tttttttttt tttctaagtg gaagatctgc
     1741 tgggtttcag gaaaaggctg ctaaaacctt cagtcacagt ctggaccctt cctggtggat
     1801 tataagccca acgtgtacag ctgtagacag gaagggtagc acatcttacc tggctgtcct
     1861 gaccgagcac ctccggacag tatccactcc agcacagtgg tcaaaggcac accaagtgag
     1921 tcgttagtgg tgtcaggaca tgtgcccctt gaagaaactg ggctctgcgg aatcctggtc
     1981 acttggaaag aagggctgaa ggaccctgct ggtttcggaa ggagcaggac tcagaacaag
     2041 gctcacccag agtcagctgg ggcaaacagc aatctcagag cactcttggc tcttgcctga
     2101 gatcacttag ttaactggcc ctgtccaatc ctatgcctcc ctcagtccct acccatgagg
     2161 gtaatgcctc tcattcctga agtctcaggc agtcctggca gacttgctgg ggttcaagaa
     2221 ccaatcacca aaggagagat cgccagagga tgacatatag aactttactc gtaatgagag
     2281 tcacacagaa ggtgcagttt tatacctatg tccacttata tatatattct cactctgacc
     2341 acacatccac ataatatata tatatatatt ataaatatat aaatgcacag gtcccccaac
     2401 ccactcctta ccaaactgta tgtcttatca tgtttataaa ctatacggga acctatatct
     2461 gtatcggtaa tttctagcaa gaaaaaagct gtggcatttt tgttatctca gctggcaaca
     2521 atagttcctg ggcttgctgg ggcaaaggtg tctgtgagaa gagtcaggaa ggaagagaag
     2581 cagggagaat cacttcaggg gaccaacatt cttagatact tagaacatca cctcgttttt
     2641 atatgcaaca catgcctgtc tggcaccccg gagcacccct actgtagaag ctgcagacgt
     2701 tagcgagaga aatggatgtc agagtgctgg aggcaagcta ggtggagctg gggaagatgt
     2761 ttctggggtt ttcaagccag ccaacaaggc agcatctaca gtgttagtcc agtgggttgg
     2821 atggacaatg tcctcctagc gttttgccag taatggactg tgcaggccag ggaggctctg
     2881 agctctggcc tcaggagagg tttagctgca gttttaacat ttaggctctt tggcccgtga
     2941 cctgctgagg gccgtgagta gtctggcagt ggggaaaact ctagtggcct tagcagatga
     3001 gggggtttca gcagccttct caggcaccct gcatcactgc ggttctgttc ctcttgatca
     3061 tcctggatca cttagacagg cagaggtcag agggccagac tcaggagtca gcctggatag
     3121 gcagcatgca ggcaagccca gtcagggaat aggggctgtt ggcccaaggg tctctggcaa
     3181 acagtctctt gagacctgaa ttccctacca gagaggatac gtgaggagta agaaatgctg
     3241 aatccaatta agagagaaaa ataataataa aaattctctt ggacaaaaaa aaaaaaaaaa
     3301 aaaaaaaaa
//
