LOCUS       NP_001101099             711 aa            linear   ROD 28-MAR-2024
DEFINITION  radial spoke head protein 4 homolog A [Rattus norvegicus].
ACCESSION   NP_001101099 XP_001057335 XP_003752009 XP_017443557 XP_228162
VERSION     NP_001101099.2
DBSOURCE    REFSEQ: accession NM_001107629.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 711)
  AUTHORS   Shinohara,K., Chen,D., Nishida,T., Misaki,K., Yonemura,S. and
            Hamada,H.
  TITLE     Absence of Radial Spokes in Mouse Node Cilia Is Required for
            Rotational Movement but Confers Ultrastructural Instability as a
            Trade-Off
  JOURNAL   Dev Cell 35 (2), 236-246 (2015)
   PUBMED   26506310
REFERENCE   2  (residues 1 to 711)
  AUTHORS   Antony,D., Becker-Heck,A., Zariwala,M.A., Schmidts,M.,
            Onoufriadis,A., Forouhan,M., Wilson,R., Taylor-Cox,T., Dewar,A.,
            Jackson,C., Goggin,P., Loges,N.T., Olbrich,H., Jaspers,M.,
            Jorissen,M., Leigh,M.W., Wolf,W.E., Daniels,M.L., Noone,P.G.,
            Ferkol,T.W., Sagel,S.D., Rosenfeld,M., Rutman,A., Dixit,A.,
            O'Callaghan,C., Lucas,J.S., Hogg,C., Scambler,P.J., Emes,R.D.,
            Chung,E.M., Shoemark,A., Knowles,M.R., Omran,H. and Mitchison,H.M.
  CONSRTM   Uk10k
  TITLE     Mutations in CCDC39 and CCDC40 are the major cause of primary
            ciliary dyskinesia with axonemal disorganization and absent inner
            dynein arms
  JOURNAL   Hum Mutat 34 (3), 462-472 (2013)
   PUBMED   23255504
REFERENCE   3  (residues 1 to 711)
  AUTHORS   Castleman,V.H., Romio,L., Chodhari,R., Hirst,R.A., de Castro,S.C.,
            Parker,K.A., Ybot-Gonzalez,P., Emes,R.D., Wilson,S.W., Wallis,C.,
            Johnson,C.A., Herrera,R.J., Rutman,A., Dixon,M., Shoemark,A.,
            Bush,A., Hogg,C., Gardiner,R.M., Reish,O., Greene,N.D.,
            O'Callaghan,C., Purton,S., Chung,E.M. and Mitchison,H.M.
  TITLE     Mutations in radial spoke head protein genes RSPH9 and RSPH4A cause
            primary ciliary dyskinesia with central-microtubular-pair
            abnormalities
  JOURNAL   Am J Hum Genet 84 (2), 197-209 (2009)
   PUBMED   19200523
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000020.1.
            
            On or before Aug 10, 2019 this sequence version replaced
            XP_003752009.1, XP_017443557.1, NP_001101099.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.78779.1,
                                           SRR26643429.57946.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760433
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..711
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20q11"
     Protein         1..711
                     /product="radial spoke head protein 4 homolog A"
                     /note="radial spokehead-like 3; radial spoke head 4
                     homolog A"
                     /calculated_mol_wt=79112
     Region          213..650
                     /region_name="Radial_spoke"
                     /note="Radial spokehead-like protein; pfam04712"
                     /db_xref="CDD:461405"
     CDS             1..711
                     /gene="Rsph4a"
                     /gene_synonym="Rshl3"
                     /coded_by="NM_001107629.2:140..2275"
                     /db_xref="GeneID:309767"
                     /db_xref="RGD:1307229"
ORIGIN      
        1 menstslkqe kenqepegae rswqgesevs ppdpalaspe yreeeqrsdt epspkrspsw
       61 gsqpraslsl ghltaglgvs ssppppplef hstplqtttt qdpvtashae rapsgitdtg
      121 tpysdpweps saarkstshy tshteesafp lsqpphpdlg grrdaawnkp kykglrfdll
      181 qeedsnsncd pdqpevgase aapsmlevav qnakayllst ssksglnlyd hlskvltkil
      241 derpvdavdv venisqdvkm shfdkkldtl hnenemlpay elaetqkalf lqghlegads
      301 eleeeiaess lpnvmesayy feqagvglgt detyriflal kqltdthpiq rcrfwgkilg
      361 lemnyivaev efrdgedeee veeegiaeer dnggseagds eedelpkply kapqaipkee
      421 srtgankyvy fvcsepgrpw vrlpsvtpaq ivtarkikkf ftgrldaaiv syppfpgnes
      481 nylraqiari sagthvsplg fyqfgeeege eeeveggrds yeensdfegi qvidlvesls
      541 nwvhhaqyil pqgrcnwfnp tqkdeeeeee deekgeepdy veqevgppll tpisedleiq
      601 nipswttrls snlvpqyaia vlrsnlwpga yafsngkkfe nlyigwghky svenytppgp
      661 ppvyqeypsg peiaemddps veeeqafrit qeaaalsaee neetedednd d
//
