LOCUS       NM_001108463            2026 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus radial spoke head 3 (Rsph3), mRNA.
ACCESSION   NM_001108463 XM_001061808 XM_003748694 XM_003753171 XM_341754
VERSION     NM_001108463.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2026)
  AUTHORS   Jeanson,L., Thomas,L., Copin,B., Coste,A., Sermet-Gaudelus,I.,
            Dastot-Le Moal,F., Duquesnoy,P., Montantin,G., Collot,N.,
            Tissier,S., Papon,J.F., Clement,A., Louis,B., Escudier,E.,
            Amselem,S. and Legendre,M.
  TITLE     Mutations in GAS8, a Gene Encoding a Nexin-Dynein Regulatory
            Complex Subunit, Cause Primary Ciliary Dyskinesia with Axonemal
            Disorganization
  JOURNAL   Hum Mutat 37 (8), 776-785 (2016)
   PUBMED   27120127
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Feb 10, 2021 this sequence version replaced NM_001108463.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments. This transcript is based on
            transcript alignments from orthologous data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.537.1, SRR26643287.419.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-751               JAXUCZ010000001.1  49558507-49559257   c
            752-839             JAXUCZ010000001.1  49551810-49551897   c
            840-981             JAXUCZ010000001.1  49529858-49529999   c
            982-1127            JAXUCZ010000001.1  49527155-49527300   c
            1128-1331           JAXUCZ010000001.1  49526033-49526236   c
            1332-1494           JAXUCZ010000001.1  49523953-49524115   c
            1495-1581           JAXUCZ010000001.1  49521960-49522046   c
            1582-2026           JAXUCZ010000001.1  49521195-49521639   c
FEATURES             Location/Qualifiers
     source          1..2026
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q11"
     gene            1..2026
                     /gene="Rsph3"
                     /gene_synonym="Rshl2"
                     /note="radial spoke head 3"
                     /db_xref="GeneID:361476"
                     /db_xref="RGD:1311306"
     exon            1..751
                     /gene="Rsph3"
                     /gene_synonym="Rshl2"
                     /inference="alignment:Splign:2.1.0"
     CDS             207..1922
                     /gene="Rsph3"
                     /gene_synonym="Rshl2"
                     /note="radial spokehead-like 2; radial spoke 3 homolog;
                     radial spoke head 3 homolog"
                     /codon_start=1
                     /product="radial spoke head protein 3 homolog"
                     /protein_id="NP_001101933.2"
                     /db_xref="GeneID:361476"
                     /db_xref="RGD:1311306"
                     /translation="MAASNIWAALPGKPPLRRCARGPAGGRDHKTEEPFSTDQSGNPA
                     GRNCLAFLPPGGTSGCSATGAGATDSLQVPGRNPRVPVTYCWGTLASRPLPREPRLLR
                     SHHPCPWHYLHVSSYEDSLAPTCFRAHLHRRGRGSTPNMASAMTDRNPRAAEASGTYT
                     YTSRPRAVACQRRRYRDSILQPVEESMNYGNIMYDRRVIRGNTYALPTGQVPGQPDPL
                     ELQQQQQARRRALARKRAQQQLRPRTPEPVEGRKHVDVQTELYLEEIADRIVEIDMEC
                     QTDAFLDRPPTPLFIPAKTGKDVATQILEGELFDFDLEVKPMLEVLVGKTIEQALLEV
                     MEEEELANLRASQYAYEEIRNVELAEVQRLEEQERRHREEKERRKRQQWEIVHKQNET
                     SQKISARAFAQRYLADLLPSVFDSLRNSGYFYDPIERDIEVGFLPWLLNEVEKTMEHS
                     MVGRTVLDMLIREVVERRINDYESKEAAQPAQRSDDVPNDPNTVPDPSVSLESQQSTT
                     LHTQKPVLDTYSSQTAPVQEKKPVEEGSSLWQNDQTELREPVGEELSQPEGSLEPESS
                     STSGQ"
     exon            752..839
                     /gene="Rsph3"
                     /gene_synonym="Rshl2"
                     /inference="alignment:Splign:2.1.0"
     exon            840..981
                     /gene="Rsph3"
                     /gene_synonym="Rshl2"
                     /inference="alignment:Splign:2.1.0"
     exon            982..1127
                     /gene="Rsph3"
                     /gene_synonym="Rshl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1128..1331
                     /gene="Rsph3"
                     /gene_synonym="Rshl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1332..1494
                     /gene="Rsph3"
                     /gene_synonym="Rshl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1495..1581
                     /gene="Rsph3"
                     /gene_synonym="Rshl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1582..2026
                     /gene="Rsph3"
                     /gene_synonym="Rshl2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccagcccgc ccctgcccca cgcgtaacag agccaggagc ccgactgcca agggcgtgtc
       61 accgccgagg gagcggggag cgcggcggcg tggcagaaga agaaacaaca ggggacggcc
      121 tttgaaagat caggaacaca tgggcaggcg ggaatggcgc tgacagcagc ctccgcactg
      181 aggcacacgg cgttaccttc gccccaatgg ccgcctctaa catctgggcg gccctgccag
      241 gcaagccgcc actgcgcagg tgcgcccgag gaccagcagg tgggcgggac cacaagacgg
      301 aagagccctt ttctaccgac cagtccggaa atccagctgg ccggaactgc ctggcgttct
      361 tacctccagg cggaacctca ggttgctcgg caaccggtgc gggcgcgact gactcgctcc
      421 aggttcccgg gagaaaccct agggtaccag tgacctactg ctggggcacc ctcgcgtccc
      481 gcccgcttcc ccgagagccg cgtcttctca ggtctcatca tccctgccct tggcactact
      541 tacacgtctc cagctacgag gactccttag cccccacctg cttcagagcc caccttcacc
      601 gaagggggcg cggttcgacc cccaacatgg cgtcggcgat gacagaccgt aaccctcggg
      661 cggcagaggc ctcaggcacc tacacctaca ccagcaggcc ccgtgccgtg gcttgccagc
      721 gccgccgcta ccgggacagc attttgcagc cagttgaaga atctatgaat tatgggaaca
      781 tcatgtatga cagaagggtg atccgaggca acacctatgc attgcccaca ggacaggtgc
      841 ctggacagcc ggaccctcta gagcttcagc agcagcagca ggccagaaga agggctcttg
      901 ccagaaaacg agcccaacag caactcagac cacgaacacc tgagcccgtg gagggcagaa
      961 agcatgtgga tgtgcagaca gaattatacc ttgaagaaat tgctgaccgc atagttgaaa
     1021 tcgacatgga atgccagaca gatgcatttc tggacagacc accaacaccc ctcttcattc
     1081 ctgccaaaac tggcaaagat gtggccactc agatactaga aggagagctc tttgactttg
     1141 accttgaagt caagccaatg ttagaggttc tggtggggaa gacgattgag caggcccttt
     1201 tagaggtgat ggaagaggag gagctggcca acctgcgggc cagtcagtac gcatatgaag
     1261 agatccggaa cgtggagctg gccgaagtgc agcgactgga agagcaagag agaaggcacc
     1321 gagaagaaaa ggaacgccgt aagagacagc agtgggagat cgtacacaag cagaatgaga
     1381 cgtcacagaa gatctcagct cgtgcatttg ctcagcggta cctggctgac cttctcccgt
     1441 ctgtctttga cagtctcagg aatagtggct atttttatga tccaattgaa agagatattg
     1501 aggtcggatt cctgccatgg ctgctgaatg aagttgagaa gaccatggag cacagcatgg
     1561 tgggaagaac tgtgcttgac atgttgatcc gtgaagtggt tgaaagaagg ataaacgatt
     1621 atgagagtaa ggaagctgca cagcccgctc agaggtcgga tgatgtgcct aacgacccta
     1681 acacagtgcc agacccctcg gtgagtctag aatcacagca gtcaaccaca ctccataccc
     1741 agaagccagt tttagataca tactcctcac agacagcacc agtccaagag aagaagcctg
     1801 tggaagaggg gtcttcctta tggcagaatg accaaacaga actgagggag cctgtaggag
     1861 aggagttgtc acaaccagaa ggatcactgg agccagagag cagctcaaca tctggtcagt
     1921 agtaatggtg cgtatgaccc aggctttaga aattatatga cactcagccg ccaagtcttt
     1981 ttgtctagtt ggctgaacaa atcaattatg attaaaaaaa taaaac
//
