LOCUS       NM_001012176            1130 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus radial spoke head component 1 (Rsph1), mRNA.
ACCESSION   NM_001012176 XM_342111
VERSION     NM_001012176.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1130)
  AUTHORS   Kang,B.W., Jeon,H.S., Chae,Y.S., Lee,S.J., Park,J.S., Choi,G.S. and
            Kim,J.G.
  TITLE     Impact of Genetic Variation in MicroRNA-binding Site on
            Susceptibility to Colorectal Cancer
  JOURNAL   Anticancer Res 36 (7), 3353-3361 (2016)
   PUBMED   27354594
REFERENCE   2  (bases 1 to 1130)
  AUTHORS   Kott,E., Legendre,M., Copin,B., Papon,J.F., Dastot-Le Moal,F.,
            Montantin,G., Duquesnoy,P., Piterboth,W., Amram,D., Bassinet,L.,
            Beucher,J., Beydon,N., Deneuville,E., Houdouin,V., Journel,H.,
            Just,J., Nathan,N., Tamalet,A., Collot,N., Jeanson,L., Le Gouez,M.,
            Vallette,B., Vojtek,A.M., Epaud,R., Coste,A., Clement,A.,
            Housset,B., Louis,B., Escudier,E. and Amselem,S.
  TITLE     Loss-of-function mutations in RSPH1 cause primary ciliary
            dyskinesia with central-complex and radial-spoke defects
  JOURNAL   Am J Hum Genet 93 (3), 561-570 (2013)
   PUBMED   23993197
REFERENCE   3  (bases 1 to 1130)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   4  (bases 1 to 1130)
  AUTHORS   Tokuhiro,K., Hirose,M., Miyagawa,Y., Tsujimura,A., Irie,S.,
            Isotani,A., Okabe,M., Toyama,Y., Ito,C., Toshimori,K., Takeda,K.,
            Oshio,S., Tainaka,H., Tsuchida,J., Okuyama,A., Nishimune,Y. and
            Tanaka,H.
  TITLE     Meichroacidin containing the membrane occupation and recognition
            nexus motif is essential for spermatozoa morphogenesis
  JOURNAL   J Biol Chem 283 (27), 19039-19048 (2008)
   PUBMED   18453535
REFERENCE   5  (bases 1 to 1130)
  AUTHORS   Hu,Y.H., Warnatz,H.J., Vanhecke,D., Wagner,F., Fiebitz,A.,
            Thamm,S., Kahlem,P., Lehrach,H., Yaspo,M.L. and Janitz,M.
  TITLE     Cell array-based intracellular localization screening reveals novel
            functional features of human chromosome 21 proteins
  JOURNAL   BMC Genomics 7, 155 (2006)
   PUBMED   16780588
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1130)
  AUTHORS   Tsuchida,J., Nishina,Y., Wakabayashi,N., Nozaki,M., Sakai,Y. and
            Nishimune,Y.
  TITLE     Molecular cloning and characterization of meichroacidin (male
            meiotic metaphase chromosome-associated acidic protein)
  JOURNAL   Dev Biol 197 (1), 67-76 (1998)
   PUBMED   9578619
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC084704.1.
            
            On Feb 11, 2005 this sequence version replaced XM_342111.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC084704.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1130
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..1130
                     /gene="Rsph1"
                     /gene_synonym="Tsga2"
                     /note="radial spoke head component 1"
                     /db_xref="GeneID:361818"
                     /db_xref="RGD:1307712"
     exon            1..108
                     /gene="Rsph1"
                     /gene_synonym="Tsga2"
                     /inference="alignment:Splign:2.1.0"
     CDS             55..957
                     /gene="Rsph1"
                     /gene_synonym="Tsga2"
                     /note="testis specific gene A2"
                     /codon_start=1
                     /product="radial spoke head 1 homolog"
                     /protein_id="NP_001012176.1"
                     /db_xref="GeneID:361818"
                     /db_xref="RGD:1307712"
                     /translation="MSDLGSEELEEEGENDLGEYEGERNELGERHGHGKARLPNGDTY
                     EGNYESGKRHGQGTYKFKNGARYVGDYVKNKKHGQGTFVYPDGSRYEGEWADDQRHGH
                     GVYYYVNNDTYTGEWFNHQRHGQGTYFYAETGSKYVGTWVHGQQEGAAELIHLNHRYQ
                     GKFINKNPVGPGKYVFDVGCEQHGEYRLTDVERGEEEEEEETLVSIVPKWKALKITEL
                     ALWTPTLSEEHPPAEGQGQEEVQGATGAGEPSDDIQAEGFEVDAEPRTGEEDIDFRQE
                     SQENSYDLDQGNPNFDEEQLDLQE"
     exon            109..222
                     /gene="Rsph1"
                     /gene_synonym="Tsga2"
                     /inference="alignment:Splign:2.1.0"
     exon            223..328
                     /gene="Rsph1"
                     /gene_synonym="Tsga2"
                     /inference="alignment:Splign:2.1.0"
     exon            329..419
                     /gene="Rsph1"
                     /gene_synonym="Tsga2"
                     /inference="alignment:Splign:2.1.0"
     exon            420..555
                     /gene="Rsph1"
                     /gene_synonym="Tsga2"
                     /inference="alignment:Splign:2.1.0"
     exon            556..627
                     /gene="Rsph1"
                     /gene_synonym="Tsga2"
                     /inference="alignment:Splign:2.1.0"
     exon            628..787
                     /gene="Rsph1"
                     /gene_synonym="Tsga2"
                     /inference="alignment:Splign:2.1.0"
     exon            788..913
                     /gene="Rsph1"
                     /gene_synonym="Tsga2"
                     /inference="alignment:Splign:2.1.0"
     exon            914..1108
                     /gene="Rsph1"
                     /gene_synonym="Tsga2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctggtacctg cttgatagag acgctgctcc ggagatcctg tctgagacca gatcatgtcg
       61 gacctgggct ctgaggagtt agaggaggag ggagagaacg atcttgggga atacgaagga
      121 gagcgcaatg aactgggaga gcggcacgga catgggaagg cacggttgcc caacggggac
      181 acatatgaag gaaactatga gtctggaaaa agacatggcc agggcaccta caaatttaag
      241 aatggggccc ggtacgttgg cgactatgtt aaaaataaga agcatggaca aggtaccttt
      301 gtctatccag atggttccag atatgaaggg gagtgggctg acgaccagag gcatggccat
      361 ggcgtttact actacgtcaa taatgacacc tacacagggg agtggttcaa tcatcaaagg
      421 cacgggcaag gcacctactt ctacgcggag accggcagta agtacgtcgg tacctgggtg
      481 cacgggcagc aggagggtgc cgccgagctc atccacctga atcacaggta ccagggcaag
      541 ttcataaaca aaaaccctgt gggcccggga aagtacgtat ttgacgtggg atgcgaacag
      601 cacggtgaat accgcctcac agatgtggaa agaggtgaag aggaggagga ggaagagaca
      661 ttagtgagta tcgttccaaa atggaaagct ctcaaaatca cagaattggc cttgtggact
      721 ccaaccctct ccgaggagca tcctcctgct gagggacaag ggcaggaaga agtccaggga
      781 gctactggtg ctggtgagcc ctcagatgac atccaggcag aaggttttga ggtcgacgca
      841 gagccgagga cgggcgaaga agacatagac ttcaggcagg agagccagga gaacagttac
      901 gacttagacc agggaaaccc gaactttgat gaagaacagt tagacctcca ggagtaagag
      961 ggagaagata gaagactaca gacacaccag gcgtgcctta attaaaacca gtcagctggg
     1021 gctggtaccc accacctggc aatctccctc cctctctcag ttgttttgca gttggaaata
     1081 aatatcccca tgttgagtgt ttgtgaaaaa aaaaaaaaaa aaaaaaaaaa
//
