LOCUS       NM_001079699            1643 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus ribosome biogenesis regulator 1 homolog (Rrs1),
            mRNA.
ACCESSION   NM_001079699 XM_001066738 XM_232622
VERSION     NM_001079699.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1643)
  AUTHORS   Sloan,K.E., Bohnsack,M.T. and Watkins,N.J.
  TITLE     The 5S RNP couples p53 homeostasis to ribosome biogenesis and
            nucleolar stress
  JOURNAL   Cell Rep 5 (1), 237-247 (2013)
   PUBMED   24120868
REFERENCE   2  (bases 1 to 1643)
  AUTHORS   Nagamachi,A., Matsui,H., Asou,H., Ozaki,Y., Aki,D., Kanai,A.,
            Takubo,K., Suda,T., Nakamura,T., Wolff,L., Honda,H. and Inaba,T.
  TITLE     Haploinsufficiency of SAMD9L, an endosome fusion facilitator,
            causes myeloid malignancies in mice mimicking human diseases with
            monosomy 7
  JOURNAL   Cancer Cell 24 (3), 305-317 (2013)
   PUBMED   24029230
REFERENCE   3  (bases 1 to 1643)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (bases 1 to 1643)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (bases 1 to 1643)
  AUTHORS   Carnemolla,A., Fossale,E., Agostoni,E., Michelazzi,S.,
            Calligaris,R., De Maso,L., Del Sal,G., MacDonald,M.E. and
            Persichetti,F.
  TITLE     Rrs1 is involved in endoplasmic reticulum stress response in
            Huntington disease
  JOURNAL   J Biol Chem 284 (27), 18167-18173 (2009)
   PUBMED   19433866
REFERENCE   6  (bases 1 to 1643)
  AUTHORS   Gambe,A.E., Matsunaga,S., Takata,H., Ono-Maniwa,R., Baba,A.,
            Uchiyama,S. and Fukui,K.
  TITLE     A nucleolar protein RRS1 contributes to chromosome congression
  JOURNAL   FEBS Lett 583 (12), 1951-1956 (2009)
   PUBMED   19465021
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC128746.1.
            
            On or before Dec 10, 2006 this sequence version replaced
            XM_232622.3, XM_001066738.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC128746.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1643
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q11"
     gene            1..1643
                     /gene="Rrs1"
                     /note="ribosome biogenesis regulator 1 homolog"
                     /db_xref="GeneID:297784"
                     /db_xref="RGD:1311403"
     exon            1..1634
                     /gene="Rrs1"
                     /inference="alignment:Splign:2.1.0"
     CDS             90..1187
                     /gene="Rrs1"
                     /note="RRS1 ribosome biogenesis regulator homolog"
                     /codon_start=1
                     /product="ribosome biogenesis regulatory protein homolog"
                     /protein_id="NP_001073167.1"
                     /db_xref="GeneID:297784"
                     /db_xref="RGD:1311403"
                     /translation="MEGQSVEELLAKAKQEEAEKLQRITVHKELELEFDLGNLLASDR
                     NPPTVLRQAGPSPEAELRALARDNTQLLVNQLWQLPTERVEEAVVARLPEPATRLPRE
                     KPLPRPRPLTRWQQFARLKGIRPKKKTNLVWDEVSGQWRRRWGYKRARDDTKEWLIEV
                     PGSADPMEDQFAKRIRAKKERVAKNELNRLRNLARAHKMQMPSSAGLHPTGHQSKEEL
                     GRAMQVAKVSTASVGRFQERLPKEKAPRGSGKKRKFQPLFGDFAAEKKNQLELLRVMN
                     SKKPQLDVTRATNKQMREEDQEEAAKRRKMSQKGKKKGGRQGPSGRRKGGPPSQGEKR
                     KGVLGGKKHSRPPALGGKKKGVPHHGGKRRK"
ORIGIN      
        1 cgcacgtggt ggctggtttt tgggctctgc catagtagca aagcattccg ctgcagcccc
       61 aaagtgaggg aacggagccg gcgagagcca tggaggggca gagtgtggag gagctgctgg
      121 ccaaagcgaa gcaggaggag gcggagaagc tgcagcgcat cacggtgcac aaggagctgg
      181 agctggagtt cgacctgggc aacctgctgg cttcggaccg caaccccccg acggtgctgc
      241 gccaggccgg accctcgccg gaggccgagc tgcgggccct ggcgcgggac aacacgcagc
      301 ttcttgtcaa ccaactatgg cagctgccaa ccgagcgcgt ggaggaggcg gtggtagcgc
      361 gcttgcctga gcccgccaca cgcctgcccc gcgagaagcc gctgccccgg ccacgaccgc
      421 tcacccgctg gcagcagttc gcgcgcctta agggcatccg tcccaagaag aagaccaacc
      481 tcgtgtggga cgaggtgagt ggccagtggc gacgccgttg gggctacaaa cgtgcccgag
      541 atgacactaa ggagtggctg atcgaggtgc ctgggagcgc agaccccatg gaagaccagt
      601 tcgccaagag gattcgggct aagaaagaac gcgtggccaa gaacgagctg aaccgactgc
      661 ggaacctggc ccgcgcgcac aagatgcaga tgcccagctc agccggcctg caccctacgg
      721 gacaccagag taaggaggag ctgggccgcg ccatgcaagt ggccaaggtc tccaccgctt
      781 ctgtgggacg cttccaggag cgcctcccca aggagaaagc gccccggggc tccggcaaga
      841 agaggaagtt tcagcccctc tttggggact ttgcagccga gaaaaaaaac caactggagc
      901 tacttcgagt catgaacagc aagaaacctc agctggacgt gacgagggcc accaacaagc
      961 agatgaggga agaggaccaa gaggaggctg ccaagaggag gaaaatgagc cagaaaggca
     1021 agaaaaaagg gggccggcaa ggaccttcgg gcaggagaaa gggcggtcca ccgagtcagg
     1081 gagagaaaag gaaaggagtc ttgggaggca agaagcattc caggccacct gccttaggtg
     1141 gcaagaagaa aggagtgccg caccatggag ggaagaggag aaagtagtgc tctcccctct
     1201 ggacctcttc tgaaaagcta gaaccgtact tgctgtaggc tggttcagga ggtggccgct
     1261 gtcctcaatg agcttgacat tgaacgggca ggtttgcctc ccctcgagtc agtgctggac
     1321 tacgaattaa tggagacact gactggttgg tgtgttttga gattatgaga attacagaaa
     1381 tactgtggtc agaaccagga ataagttaat gcctgccttt ttatcttgac tttggatgct
     1441 gggtaaaggt tgatcaaatt tctaggttat agtagactgg tttcagcatt tttgcattat
     1501 tttggtaata aagcttgtat atttatcaaa gcaggaagaa gggggaaatt tacaagtttg
     1561 ccggtagaag ttatatgtga agccagtgac atgggtacca atacgtgtgt gcttgcaaaa
     1621 aaaaaaaaaa aaaaaaaaaa aaa
//
