LOCUS       NM_001013434            2282 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus RAS related 2 (Rras2), mRNA.
ACCESSION   NM_001013434 XM_344953
VERSION     NM_001013434.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2282)
  AUTHORS   Kuo JC, Han X, Hsiao CT, Yates JR 3rd and Waterman CM.
  TITLE     Analysis of the myosin-II-responsive focal adhesion proteome
            reveals a role for beta-Pix in negative regulation of focal
            adhesion maturation
  JOURNAL   Nat Cell Biol 13 (4), 383-393 (2011)
   PUBMED   21423176
REFERENCE   2  (bases 1 to 2282)
  AUTHORS   Kim JM, Park SK, Yang JJ, Shin ES, Lee JY, Yun JY, Kim JS, Park SS
            and Jeon BS.
  TITLE     SNPs in axon guidance pathway genes and susceptibility for
            Parkinson's disease in the Korean population
  JOURNAL   J Hum Genet 56 (2), 125-129 (2011)
   PUBMED   21085126
REFERENCE   3  (bases 1 to 2282)
  AUTHORS   Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta
            R, Wang NS and Knepper MA.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   4  (bases 1 to 2282)
  AUTHORS   Foster LJ, Zeemann PA, Li C, Mann M, Jensen ON and Kassem M.
  TITLE     Differential expression profiling of membrane proteins by
            quantitative proteomics in a human mesenchymal stem cell line
            undergoing osteoblast differentiation
  JOURNAL   Stem Cells 23 (9), 1367-1377 (2005)
   PUBMED   16210410
REFERENCE   5  (bases 1 to 2282)
  AUTHORS   Huang Y, Rangwala F, Fulkerson PC, Ling B, Reed E, Cox AD, Kamholz
            J and Ratner N.
  TITLE     Role of TC21/R-Ras2 in enhanced migration of
            neurofibromin-deficient Schwann cells
  JOURNAL   Oncogene 23 (2), 368-378 (2004)
   PUBMED   14724565
REFERENCE   6  (bases 1 to 2282)
  AUTHORS   Murphy GA, Graham SM, Morita S, Reks SE, Rogers-Graham K, Vojtek A,
            Kelley GG and Der CJ.
  TITLE     Involvement of phosphatidylinositol 3-kinase, but not RalGDS, in
            TC21/R-Ras2-mediated transformation
  JOURNAL   J Biol Chem 277 (12), 9966-9975 (2002)
   PUBMED   11788587
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC091333.1.
            
            On Apr 20, 2005 this sequence version replaced XM_344953.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC091333.1, CK476402.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760396
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2282
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q33"
     gene            1..2282
                     /gene="Rras2"
                     /note="RAS related 2"
                     /db_xref="GeneID:365355"
                     /db_xref="RGD:1310793"
     exon            1..371
                     /gene="Rras2"
                     /inference="alignment:Splign:2.1.0"
     CDS             264..878
                     /gene="Rras2"
                     /EC_number="3.6.5.2"
                     /note="related RAS viral (r-ras) oncogene homolog 2"
                     /codon_start=1
                     /product="ras-related protein R-Ras2"
                     /protein_id="NP_001013452.1"
                     /db_xref="GeneID:365355"
                     /db_xref="RGD:1310793"
                     /translation="MAAAGWRDGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYD
                     PTIEDSYTKQCVIDDRAARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFE
                     EIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKI
                     RMNVDQAFHELVRVIRKFQEQECPPSPEPTRKEKDKKGCHCVIF"
     exon            372..459
                     /gene="Rras2"
                     /inference="alignment:Splign:2.1.0"
     exon            460..562
                     /gene="Rras2"
                     /inference="alignment:Splign:2.1.0"
     exon            563..671
                     /gene="Rras2"
                     /inference="alignment:Splign:2.1.0"
     exon            672..790
                     /gene="Rras2"
                     /inference="alignment:Splign:2.1.0"
     exon            791..2257
                     /gene="Rras2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggtgctag aggctgcgtt cggctgcgct gcagagccgc gaagaggatc gcgctccctg
       61 gccgctgcgt cctctgccct ggagccttct cggctctcct gcgtctcggg caactcccaa
      121 ccagtcccgg ggatagcgct ccgcggccct ccaggccact cgcgggcccc gcgcgctcta
      181 ccgcctgtaa cccagccggc cgcactcgtc cccggagccg ggcctagggc gcgcggcggc
      241 cgggctgggc tcggggcgtc ccgatggccg cggccggctg gcgcgacggc tccggccagg
      301 agaagtaccg gctcgtggtg gtcggcggtg gcggcgtggg caagtcggcg ctcaccatcc
      361 agttcatcca gtcctacttt gtgacggact atgatccaac catcgaagac tcatacacaa
      421 aacagtgtgt gatcgatgat cgagcggccc ggctggacat tttggataca gccggacaag
      481 aggagtttgg agccatgaga gagcagtaca tgaggacagg cgagggcttc ctgttggtct
      541 tctcagttac agatagaggc agttttgaag aaatctataa gtttcaaaga cagattctca
      601 gagtaaagga tcgtgatgag tttcccatga ttttaattgg caataaagca gacctggacc
      661 atcagagaca ggtaacgcag gaagaagggc agcagttagc gcggcagctc aaggtcacgt
      721 atatggaggc gtcggcaaag atcaggatga atgtagatca agctttccac gaacttgtcc
      781 gagttatcag gaagtttcaa gaacaagaat gtcctccttc accagaacca acccggaaag
      841 aaaaagacaa gaaaggctgc cattgtgtca ttttctaaag agtcccttaa ggtttagcta
      901 acaactgcca gggaagccct catctctgct accgtttaca tcatccggta cctttgtagc
      961 cttagaccga tgatcaccgt gttagcctta caccaagaag ctggctaatc ctttatgtga
     1021 agctaatgta acggtctttc ccagacttgt gtacaggaaa cactaaggct gcttcagact
     1081 cctttagaac acacgtctac acacacgatg cagtctgtaa gggcttttag tagaggtgaa
     1141 caggtttgga gcccgagctg tttgctaagc tgaagtcata ggttgtgaag taatttttaa
     1201 cttctggaat catgttgcct actgttactc taaatagaaa tataggaagg tttttttttt
     1261 ttaaatgtga atttttgcct atctttaaaa ctttggatgt caactttcat taaccttaaa
     1321 tacactgaat ggaatctaca gaagtgagac atctcagaac tttcctgatg ctacggcttt
     1381 tgtttttcca gtggccagaa taccaaaatg cctgttgtat ttatggatta aaaactgctg
     1441 attgagctat tgttattctg cctccttcaa gatgacagta ttctctgtgg ccaagtgttt
     1501 ggactggttc tgcacttaga tgtttcagtg aacttgattt cttttcacag ccgtggtaag
     1561 ggtaagagtg aatggttctt gtctgtcttc ctgttcaaat attcctgggt aagggattaa
     1621 aaaagaaaac ccacacaagc taaagctgtt ttcgtttgat gtaatataaa atatggaatc
     1681 gatcttccca aagtcagaga tgattaatgt ttttgctata tacttttata cgttattttc
     1741 ttatcaaact agttaacaag tatttttata tgtttgtaag cgaatatgct ttcacagcgc
     1801 accttgtgta tatgtaaaga tgagtattta agtctcactg ttcaccgtta gctgacaaag
     1861 agaacgtgga agccacggcg accatggctt ttgcttgctg gcttggtcct tgttctatcc
     1921 actggtggcc agtaatcaga aacccttccc aacagaacgc aacaggatga gactgtgaag
     1981 tcacgttcaa tgtccccgct agatattgac tgttatagca agtattacat gtaaaacctc
     2041 tacttgacaa ttagtgtaac tgtggatggc ttctggtttt gtttttaact ctgtggattg
     2101 tgtttaagca attcaaagtg ttttcctggt cttgagactc tcagtggtat tgcacagtgc
     2161 tcactttact gaatgtgtac aacagcccca tgacgtttat aaagtggacc cttgtatagc
     2221 ttcaggtgct agaattaaag ttgatctgtt atcaccaaaa aaaaaaaaaa aaaaaaaaaa
     2281 aa
//
