LOCUS       NM_001106641            1473 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus Ras-related GTP binding D (Rragd), mRNA.
ACCESSION   NM_001106641 XM_001063809 XM_216363
VERSION     NM_001106641.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1473)
  AUTHORS   Bar-Peled L and Sabatini DM.
  TITLE     Regulation of mTORC1 by amino acids
  JOURNAL   Trends Cell Biol 24 (7), 400-406 (2014)
   PUBMED   24698685
  REMARK    Review article
REFERENCE   2  (bases 1 to 1473)
  AUTHORS   Han JM, Jeong SJ, Park MC, Kim G, Kwon NH, Kim HK, Ha SH, Ryu SH
            and Kim S.
  TITLE     Leucyl-tRNA synthetase is an intracellular leucine sensor for the
            mTORC1-signaling pathway
  JOURNAL   Cell 149 (2), 410-424 (2012)
   PUBMED   22424946
REFERENCE   3  (bases 1 to 1473)
  AUTHORS   Sancak Y, Bar-Peled L, Zoncu R, Markhard AL, Nada S and Sabatini
            DM.
  TITLE     Ragulator-Rag complex targets mTORC1 to the lysosomal surface and
            is necessary for its activation by amino acids
  JOURNAL   Cell 141 (2), 290-303 (2010)
   PUBMED   20381137
REFERENCE   4  (bases 1 to 1473)
  AUTHORS   Ma XM and Blenis J.
  TITLE     Molecular mechanisms of mTOR-mediated translational control
  JOURNAL   Nat Rev Mol Cell Biol 10 (5), 307-318 (2009)
   PUBMED   19339977
  REMARK    Review article
REFERENCE   5  (bases 1 to 1473)
  AUTHORS   Sekiguchi T, Hirose E, Nakashima N, Ii M and Nishimoto T.
  TITLE     Novel G proteins, Rag C and Rag D, interact with GTP-binding
            proteins, Rag A and Rag B
  JOURNAL   J Biol Chem 276 (10), 7246-7257 (2001)
   PUBMED   11073942
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC167014.1.
            
            On May 11, 2008 this sequence version replaced NM_001106641.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC167014.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1473
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q21"
     gene            1..1473
                     /gene="Rragd"
                     /note="Ras-related GTP binding D"
                     /db_xref="GeneID:297960"
                     /db_xref="RGD:1310007"
     exon            1..244
                     /gene="Rragd"
                     /inference="alignment:Splign:2.1.0"
     CDS             100..1299
                     /gene="Rragd"
                     /codon_start=1
                     /product="ras-related GTP-binding protein D"
                     /protein_id="NP_001100111.1"
                     /db_xref="GeneID:297960"
                     /db_xref="RGD:1310007"
                     /translation="MSQVLGKPQPQGEDGGDDEEEDELVGLAGYEDGPESSDAELDSG
                     PEEGVLDFSDPFSTEVKPRILLMGLRRSGKSSIQKVVFHKMSPSETLFLESTNRICRE
                     DVSNSSFVNFQIWDFPGQIDFFDPTFDYEMIFRGTGALIFVIDSQDDYMEALARLHLT
                     VTRAYKVNTDINFEVFIHKVDGLSDDHKIETQRDIHQRANDDLADAGLEKIHLSFYLT
                     SIYDHSIFEAFSKVVQKLIPQLPTLENLLNIFISNSGIEKAFLFDVVSKIYIATDSTP
                     VDMQTYELCCDMIDVVIDISCIYGLKEDGAGAPYDKDSTAIIKLNNTTVLYLKEVTKF
                     LALVCFVREESFERKGLIDYNFHCFRKAIHEVFEVRMKMVKSRKAQSRLPKKTGATPN
                     GTPRVLL"
     exon            245..540
                     /gene="Rragd"
                     /inference="alignment:Splign:2.1.0"
     exon            541..740
                     /gene="Rragd"
                     /inference="alignment:Splign:2.1.0"
     exon            741..855
                     /gene="Rragd"
                     /inference="alignment:Splign:2.1.0"
     exon            856..998
                     /gene="Rragd"
                     /inference="alignment:Splign:2.1.0"
     exon            999..1147
                     /gene="Rragd"
                     /inference="alignment:Splign:2.1.0"
     exon            1148..1449
                     /gene="Rragd"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggctgggct ccgtgccacc ccctcgctca ccaggagcgg ccccggggcg ctgcgggcca
       61 ctcggcccac gcgggacctc ggaggcaagc gtgggcgtga tgagccaggt gctgggcaag
      121 ccgcagccgc agggtgagga cggcggcgac gacgaggagg aggatgagct ggtggggctg
      181 gcaggctacg aggatggacc ggagtcctcc gacgccgagc tggacagcgg accggaggag
      241 ggagttctgg acttcagcga ccccttcagc actgaggtga agcccagaat tctgctcatg
      301 ggtctcagga ggagtggcaa gtcgtccata cagaaagttg tctttcacaa aatgtccccg
      361 agtgagacgc tgttcctgga gagtaccaac aggatctgcc gggaagacgt ctccaacagc
      421 agctttgtca acttccagat ttgggacttc ccagggcaga ttgacttttt tgaccctaca
      481 tttgactatg agatgatctt ccgagggaca ggagcactga tctttgtcat agactcccag
      541 gatgactata tggaggcgct ggccaggctc catctcactg tgaccagggc ctacaaggtg
      601 aacactgata tcaacttcga ggtgtttatt cataaagtgg acggtctgtc ggatgatcac
      661 aaaatcgaaa cccaaagaga cattcaccag agggcaaacg atgaccttgc cgatgctggg
      721 ttagagaaaa ttcacctgag cttttatctg acaagcatat acgatcattc aatattcgaa
      781 gcctttagca aagtggttca gaaactgatc ccgcagctcc cgacgctgga gaatctgctg
      841 aacatcttta tctcaaattc tggaattgaa aaagcatttc tatttgacgt ggtcagtaag
      901 atttatattg caaccgacag cacgccggtg gatatgcaga cgtatgagct gtgctgcgac
      961 atgattgatg tggtgattga catctcttgt atttatggcc tcaaagaaga tggagcgggc
     1021 gccccgtatg acaaggactc gacagccatt ataaaactga ataatacaac ggttctttat
     1081 ctaaaagagg tcacgaagtt cttggcgctc gtttgctttg tcagagagga aagctttgaa
     1141 agaaaaggcc ttattgatta taatttccac tgcttccgga aggccatcca tgaagtcttc
     1201 gaggtgagga tgaagatggt gaaatctcgg aaggcccaga gtcggttacc caagaagact
     1261 ggagctactc ccaatgggac tcctcgggtg ctgctgtaag gggagccgtc aggagccaga
     1321 gcccagacct cagtgaggag gctgttaaac taaactggac tgcaggaagg ctgagccctg
     1381 actcagacat attaaggaaa aagaaaactt acccttttta aaataaaata agcactttga
     1441 agcaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//
