LOCUS       NM_001371379            2483 bp    mRNA    linear   ROD 06-NOV-2024
DEFINITION  Rattus norvegicus ribosomal protein S6 kinase-like 1 (Rps6kl1),
            transcript variant 2, mRNA.
ACCESSION   NM_001371379 XM_006225854 XM_006240317
VERSION     NM_001371379.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2483)
  AUTHORS   Bonaldo,M.F., Lennon,G. and Soares,M.B.
  TITLE     Normalization and subtraction: two approaches to facilitate gene
            discovery
  JOURNAL   Genome Res 6 (9), 791-806 (1996)
   PUBMED   8889548
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1 and BE106822.1.
            
            On or before Jul 10, 2019 this sequence version replaced
            XM_006240317.3, XM_006225854.3.
            
            Transcript Variant: This variant (2) uses an alternate in-frame
            splice site close to the 3' region, compared to variant 1. This
            results in a protein (isoform 2), one aa shorter compared to
            isoform 1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.36488.1,
                                           SRR26643290.23603.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760386,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-107               JAXUCZ010000006.1  110530823-110530929 c
            108-389             JAXUCZ010000006.1  110529258-110529539 c
            390-514             JAXUCZ010000006.1  110527302-110527426 c
            515-607             JAXUCZ010000006.1  110526074-110526166 c
            608-655             JAXUCZ010000006.1  110519543-110519590 c
            656-788             JAXUCZ010000006.1  110519066-110519198 c
            789-1379            JAXUCZ010000006.1  110517792-110518382 c
            1380-1469           JAXUCZ010000006.1  110517370-110517459 c
            1470-1552           JAXUCZ010000006.1  110517143-110517225 c
            1553-1648           JAXUCZ010000006.1  110515479-110515574 c
            1649-2465           JAXUCZ010000006.1  110514323-110515139 c
            2466-2483           BE106822.1         1-18                c
FEATURES             Location/Qualifiers
     source          1..2483
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q31"
     gene            1..2483
                     /gene="Rps6kl1"
                     /note="ribosomal protein S6 kinase-like 1"
                     /db_xref="GeneID:299202"
                     /db_xref="RGD:1309493"
     exon            1..107
                     /gene="Rps6kl1"
                     /inference="alignment:Splign:2.1.0"
     exon            108..389
                     /gene="Rps6kl1"
                     /inference="alignment:Splign:2.1.0"
     CDS             125..1759
                     /gene="Rps6kl1"
                     /EC_number="2.7.11.1"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /codon_start=1
                     /product="ribosomal protein S6 kinase-like 1 isoform 2"
                     /protein_id="NP_001358308.1"
                     /db_xref="GeneID:299202"
                     /db_xref="RGD:1309493"
                     /translation="MSLVACECPPGPGLEPEPCSRARSQACMYLEQIRHWVAAGTADM
                     TKRDYLVDAATQIHLALERDVSEDYEAAFNYYQNGVDVLLRGVHVDPNKERCEAVKLK
                     ITKYLRRAEEIFNCHLQRTLGSGTSPNTGFSSLRLRPIRTLSSALEQLKGCRVVGIIK
                     KVQVVQDPATGGTFVVKSLPRCHMVSRERLTIIPHGVPFMTKLLRYFVSEDSIFLHLE
                     HVQGGTLWSHLLSQDHFQHSGLKSGSAQEKCKVQLSTGHNLTTPAKLPPGHTLRQDRT
                     PVEPPWTSQSLPPALQLQKEADGEPAPRTSIVYSSDLTEAPCGHLHSQVRRAGQSSNP
                     APSQRLHWVREGADRVLGAYGRGRAQNPPSANRASLGSGRAAWSLWEGQVKQWAAEML
                     LALEALHEQGVLCRDLNPQNLLLDQAGHIQLTYFGQWSEVEPQCSQEAVDCLYSAPEV
                     GGISELTEACDWWSYGSLLYELLTGMALSQSHPSGFQAHTQLQLPEWLSRPAASLLTE
                     LLQFDPQRRLGAGGGGTSKLKSHPFFSSIQWSRLTG"
     exon            390..514
                     /gene="Rps6kl1"
                     /inference="alignment:Splign:2.1.0"
     exon            515..607
                     /gene="Rps6kl1"
                     /inference="alignment:Splign:2.1.0"
     exon            608..655
                     /gene="Rps6kl1"
                     /inference="alignment:Splign:2.1.0"
     exon            656..788
                     /gene="Rps6kl1"
                     /inference="alignment:Splign:2.1.0"
     exon            789..1379
                     /gene="Rps6kl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1380..1469
                     /gene="Rps6kl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1470..1552
                     /gene="Rps6kl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1553..1648
                     /gene="Rps6kl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1649..2466
                     /gene="Rps6kl1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgccccaccc ccacccccag gcacctgcgg aagggtggga ggcacagaca gagagccttg
       61 cagaggtgaa gggacagcct tggcctggag ctctggcacg cggacaggtc gcagcagggc
      121 cactatgagc ctagtagcct gtgagtgtcc accaggccca ggcctggagc cagagccttg
      181 ttcacgggca cggtcccagg cctgcatgta cctggagcag attcgtcact gggtagctgc
      241 agggacggct gacatgacca agcgtgacta cctggtagac gcggcgacac agatccacct
      301 ggcgctggag cgagacgtca gcgaggatta cgaggctgcc ttcaactact accagaatgg
      361 tgtggacgtg ctgctccgcg gtgtgcatgt tgaccccaac aaggagaggt gtgaagccgt
      421 aaaactgaaa attaccaagt acctacggag ggcagaggag atcttcaact gccacctgca
      481 gcggacactg ggcagtggaa ccagtcccaa cacgggtttc agcagcttga ggctgcggcc
      541 catccgcacc ctgagctctg ctctggagca gctgaaggga tgcagggttg ttgggatcat
      601 caagaaggtg caggtggtcc aggacccagc aaccggagga acctttgtcg tgaagagcct
      661 tcccaggtgt cacatggtga gccgggagcg gctgaccatc atcccacacg gcgtcccctt
      721 catgacaaaa ttgttgcgat acttcgtgag cgaggactcc atcttcctgc acctggagca
      781 cgtgcaagga ggcacccttt ggtcacatct actctcccag gaccactttc aacactcggg
      841 gctcaagtct ggctctgccc aggagaagtg caaagtccaa ctcagcactg gccacaacct
      901 tacgacccca gcaaagctcc caccaggcca caccttgagg caggacagaa ccccagtgga
      961 gcctccgtgg acttcccaga gccttccccc agccctccag cttcagaaag aggctgacgg
     1021 tgaacctgca cccaggacca gtattgtcta ctcttcagac ctcacagagg ccccgtgtgg
     1081 ccacttgcac agtcaagtca ggcgagctgg ccagagttcg aacccagcac ccagtcaaag
     1141 gctccactgg gtacgagaag gggctgaccg ggtgctaggg gcctatggcc gaggcagggc
     1201 tcagaacccc ccatcagcaa acagggccag cctggggagc ggaagagctg cctggagcct
     1261 gtgggaggga caggtgaagc agtgggcggc tgagatgctg ctggcactgg aggcactgca
     1321 tgagcagggg gtgctgtgca gggacctcaa cccacagaac ctgctcctgg accaggcagg
     1381 tcacatccaa ctcacgtatt ttggccagtg gtcagaagtg gagccccagt gcagccagga
     1441 agctgtggac tgtctgtaca gcgctccaga ggttgggggc atttctgagc tgaccgaagc
     1501 ctgtgactgg tggagctacg ggtcacttct gtatgaattg ctcacaggaa tggcgctgtc
     1561 ccagagccac ccctcaggat tccaagccca cacccaactt cagctgcctg agtggctcag
     1621 tcgcccagca gcctctctgc tgactgagct gctgcagttc gatccccagc ggcgcttagg
     1681 tgccggaggt ggtggcacca gcaaactcaa gtcccacccc tttttcagtt ctatccagtg
     1741 gagcaggcta acggggtaag aggttggtaa gtggacaaag cagccggccc agttctcttg
     1801 tctaccagct gggccagccc ctctcatcag tggacttcag gggaagatcg tggagcagca
     1861 gccacttttt ctgcttatga cctgcttggg cctcagactg agcactgcta caggcctgga
     1921 gaagctgctg gaagggcagt gaggtgcacc ctgctgaaca acctacactc atcagtcaac
     1981 agatacctgt tgaacgcaca gcttgtacca tgagccggga ccgtcgtgtt taaagggcgc
     2041 cctctgttgc tctagttccg aaccgctcaa cacttgcaga gccaactgag gaatctgggg
     2101 acactgccat ttgtctaaca cgcagggcaa atctggagac atctcaggac actggacctc
     2161 tggttcagta gccccaaacc aggactgtcc tgggtccact ttagtcatgc aactactggg
     2221 ctgctacaac cagaggctgt tcctataggc gtctgggtgc tagggaggtg cttagtctgt
     2281 agggtgaagt ggggaggggg gcatagtatg atccactccc cagtcctgac cttaacttct
     2341 gatttctgac tttggagaat agaattaagg ggaggaagcc agtggggtta agagagggat
     2401 tagaatgcag ttgtaccact tagacagttt ggaaacagaa taaagtgctt tattctctgg
     2461 ctggctaaaa aaaaaaaaaa aaa
//
