LOCUS       NM_001009239             843 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus ribosomal protein S3 (Rps3), mRNA.
ACCESSION   NM_001009239 XM_341888
VERSION     NM_001009239.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 843)
  AUTHORS   Zhou,D., Chen,L., Wang,Y., Gan,L., Yuan,M., Zhang,L. and Chen,F.
  TITLE     RNA binding protein RPS3 mediates microglial polarization by
            activating NLRP3 inflammasome via SIRT1 in ischemic stroke
  JOURNAL   J Stroke Cerebrovasc Dis 32 (6), 107132 (2023)
   PUBMED   37087770
  REMARK    GeneRIF: RNA binding protein RPS3 mediates microglial polarization
            by activating NLRP3 inflammasome via SIRT1 in ischemic stroke.
REFERENCE   2  (bases 1 to 843)
  AUTHORS   Milochau,A., Lagree,V., Benassy,M.N., Chaignepain,S., Papin,J.,
            Garcia-Arcos,I., Lajoix,A., Monterrat,C., Coudert,L.,
            Schmitter,J.M., Ochoa,B. and Lang,J.
  TITLE     Synaptotagmin 11 interacts with components of the RNA-induced
            silencing complex RISC in clonal pancreatic beta-cells
  JOURNAL   FEBS Lett 588 (14), 2217-2222 (2014)
   PUBMED   24882364
REFERENCE   3  (bases 1 to 843)
  AUTHORS   Voorhees,R.M., Fernandez,I.S., Scheres,S.H. and Hegde,R.S.
  TITLE     Structure of the mammalian ribosome-Sec61 complex to 3.4 A
            resolution
  JOURNAL   Cell 157 (7), 1632-1643 (2014)
   PUBMED   24930395
REFERENCE   4  (bases 1 to 843)
  AUTHORS   Zanivan,S., Maione,F., Hein,M.Y., Hernandez-Fernaud,J.R.,
            Ostasiewicz,P., Giraudo,E. and Mann,M.
  TITLE     SILAC-based proteomics of human primary endothelial cell
            morphogenesis unveils tumor angiogenic markers
  JOURNAL   Mol Cell Proteomics 12 (12), 3599-3611 (2013)
   PUBMED   23979707
REFERENCE   5  (bases 1 to 843)
  AUTHORS   Kim,Y., Kim,H.D. and Kim,J.
  TITLE     Cytoplasmic ribosomal protein S3 (rpS3) plays a pivotal role in
            mitochondrial DNA damage surveillance
  JOURNAL   Biochim Biophys Acta 1833 (12), 2943-2952 (2013)
   PUBMED   23911537
REFERENCE   6  (bases 1 to 843)
  AUTHORS   Vladimirov,S.N., Ivanov,A.V., Karpova,G.G., Musolyamov,A.K.,
            Egorov,T.A., Thiede,B., Wittmann-Liebold,B. and Otto,A.
  TITLE     Characterization of the human small-ribosomal-subunit proteins by
            N-terminal and internal sequencing, and mass spectrometry
  JOURNAL   Eur J Biochem 239 (1), 144-149 (1996)
   PUBMED   8706699
REFERENCE   7  (bases 1 to 843)
  AUTHORS   Kim,J., Chubatsu,L.S., Admon,A., Stahl,J., Fellous,R. and Linn,S.
  TITLE     Implication of mammalian ribosomal protein S3 in the processing of
            DNA damage
  JOURNAL   J Biol Chem 270 (23), 13620-13629 (1995)
   PUBMED   7775413
REFERENCE   8  (bases 1 to 843)
  AUTHORS   Chan,Y.L., Devi,K.R., Olvera,J. and Wool,I.G.
  TITLE     The primary structure of rat ribosomal protein S3
  JOURNAL   Arch Biochem Biophys 283 (2), 546-550 (1990)
   PUBMED   2275563
REFERENCE   9  (bases 1 to 843)
  AUTHORS   Lutsch,G., Stahl,J., Kargel,H.J., Noll,F. and Bielka,H.
  TITLE     Immunoelectron microscopic studies on the location of ribosomal
            proteins on the surface of the 40S ribosomal subunit from rat liver
  JOURNAL   Eur J Cell Biol 51 (1), 140-150 (1990)
   PUBMED   2328735
REFERENCE   10 (bases 1 to 843)
  AUTHORS   Collatz,E., Wool,I.G., Lin,A. and Stoffler,G.
  TITLE     The isolation of eukaryotic ribosomal proteins. The purification
            and characterization of the 40 S ribosomal subunit proteins S2, S3,
            S4, S5, S6, S7, S8, S9, S13, S23/S24, S27, and S28
  JOURNAL   J Biol Chem 251 (15), 4666-4672 (1976)
   PUBMED   947902
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC088450.1.
            
            On Jan 7, 2005 this sequence version replaced XM_341888.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088450.1, FN800823.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760393
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..843
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q32"
     gene            1..843
                     /gene="Rps3"
                     /note="ribosomal protein S3"
                     /db_xref="GeneID:140654"
                     /db_xref="RGD:619888"
     exon            1..42
                     /gene="Rps3"
                     /inference="alignment:Splign:2.1.0"
     CDS             13..744
                     /gene="Rps3"
                     /EC_number="4.2.99.18"
                     /note="40S ribosomal protein S3"
                     /codon_start=1
                     /product="small ribosomal subunit protein uS3"
                     /protein_id="NP_001009239.1"
                     /db_xref="GeneID:140654"
                     /db_xref="RGD:619888"
                     /translation="MAVQISKKRKFVADGIFKAELNEFLTRELAEDGYSGVEVRVTPT
                     RTEIIILATRTQNVLGEKGRRIRELTAVVQKRFGFPEGSVELYAEKVATRGLCAIAQA
                     ESLRYKLLGGLAVRRACYGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHS
                     GDPVNYYVDTAVRHVLLRQGVLGIKVKIMLPWDPSGKIGPKKPLPDHVSIVEPKDEIL
                     PTTPISEQKGGKPEPPAMPQPVPTA"
     exon            43..173
                     /gene="Rps3"
                     /inference="alignment:Splign:2.1.0"
     exon            174..267
                     /gene="Rps3"
                     /inference="alignment:Splign:2.1.0"
     exon            268..362
                     /gene="Rps3"
                     /inference="alignment:Splign:2.1.0"
     exon            363..550
                     /gene="Rps3"
                     /inference="alignment:Splign:2.1.0"
     exon            551..747
                     /gene="Rps3"
                     /inference="alignment:Splign:2.1.0"
     exon            748..819
                     /gene="Rps3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcggcagca agatggcggt gcagatttcc aagaagagga agtttgtagc tgatggcatc
       61 ttcaaagctg aactgaatga gtttctcact cgggagctgg ctgaagatgg ctactctgga
      121 gttgaagtcc gagttacgcc gaccagaaca gaaatcatta ttttagccac cagaacacag
      181 aatgttcttg gggagaaggg tcgtcggatc agagagctga ctgcagttgt ccagaagcgg
      241 tttggcttcc ctgaaggcag cgtagagctg tatgcagaaa aagtggccac aagaggtctg
      301 tgtgccattg cccaggcaga gtctctacgc tacaaactct taggagggct tgcagttcga
      361 agggcctgct atggtgtgct tcggttcatt atggaaagtg gggccaaggg ctgtgaggtt
      421 gtggtctctg ggaagctccg aggacagagg gccaagtcca tgaagtttgt ggatggtctg
      481 atgattcaca gcggagaccc tgttaactac tatgttgaca ctgctgtgcg ccatgtgctc
      541 ctcagacagg gcgtgctggg catcaaagtg aagatcatgc tgccctggga cccaagtggt
      601 aagattggtc ccaagaagcc tctgcctgat catgtgagca ttgtggaacc taaagatgaa
      661 atcttgccca ccacccccat ctcagaacag aagggtggga agccagagcc acccgccatg
      721 cctcagccag tgcctacagc ataacagggt cttggcagct gcatctggag gctggatgtt
      781 gtcttgtaaa gacgtttaat aaaatcttga acaaagacaa aaaaaaaaaa aaaaaaaaaa
      841 aaa
//
