LOCUS       NM_053982                449 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ribosomal protein S15a (Rps15a), mRNA.
ACCESSION   NM_053982 XM_212877
VERSION     NM_053982.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Chen,R., He,J., Wang,C., Xu,M., An,N. and Bai,Y.
  TITLE     RPS15A Mediates PI3K/AKT Signaling-Induced Parathyroid Cell
            Proliferation in Rats with Secondary Hyperparathyroidism
  JOURNAL   Ann Clin Lab Sci 53 (2), 313-321 (2023)
   PUBMED   37094854
  REMARK    GeneRIF: RPS15A Mediates PI3K/AKT Signaling-Induced Parathyroid
            Cell Proliferation in Rats with Secondary Hyperparathyroidism.
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Zanivan,S., Maione,F., Hein,M.Y., Hernandez-Fernaud,J.R.,
            Ostasiewicz,P., Giraudo,E. and Mann,M.
  TITLE     SILAC-based proteomics of human primary endothelial cell
            morphogenesis unveils tumor angiogenic markers
  JOURNAL   Mol Cell Proteomics 12 (12), 3599-3611 (2013)
   PUBMED   23979707
REFERENCE   3  (bases 1 to 449)
  AUTHORS   Anger,A.M., Armache,J.P., Berninghausen,O., Habeck,M., Subklewe,M.,
            Wilson,D.N. and Beckmann,R.
  TITLE     Structures of the human and Drosophila 80S ribosome
  JOURNAL   Nature 497 (7447), 80-85 (2013)
   PUBMED   23636399
REFERENCE   4  (bases 1 to 449)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   5  (bases 1 to 449)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   6  (bases 1 to 449)
  AUTHORS   Yu,Y., Ji,H., Doudna,J.A. and Leary,J.A.
  TITLE     Mass spectrometric analysis of the human 40S ribosomal subunit:
            native and HCV IRES-bound complexes
  JOURNAL   Protein Sci 14 (6), 1438-1446 (2005)
   PUBMED   15883184
REFERENCE   7  (bases 1 to 449)
  AUTHORS   Lian,Z., Liu,J., Li,L., Li,X., Tufan,N.L., Wu,M.C., Wang,H.Y.,
            Arbuthnot,P., Kew,M. and Feitelson,M.A.
  TITLE     Human S15a expression is upregulated by hepatitis B virus X protein
  JOURNAL   Mol Carcinog 40 (1), 34-46 (2004)
   PUBMED   15108328
REFERENCE   8  (bases 1 to 449)
  AUTHORS   Vladimirov,S.N., Ivanov,A.V., Karpova,G.G., Musolyamov,A.K.,
            Egorov,T.A., Thiede,B., Wittmann-Liebold,B. and Otto,A.
  TITLE     Characterization of the human small-ribosomal-subunit proteins by
            N-terminal and internal sequencing, and mass spectrometry
  JOURNAL   Eur J Biochem 239 (1), 144-149 (1996)
   PUBMED   8706699
REFERENCE   9  (bases 1 to 449)
  AUTHORS   Chan,Y.L., Olvera,J., Paz,V. and Wool,I.G.
  TITLE     The primary structure of rat ribosomal protein S15a
  JOURNAL   Biochem Biophys Res Commun 200 (3), 1498-1504 (1994)
   PUBMED   8185605
REFERENCE   10 (bases 1 to 449)
  AUTHORS   Collatz,E., Ulbrich,N., Tsurugi,K., Lightfoot,H.N., MacKinlay,W.,
            Lin,A. and Wool,I.G.
  TITLE     Isolation of eukaryotic ribosomal proteins. Purification and
            characterization of the 40 S ribosomal subunit proteins Sa, Sc,
            S3a, S3b, S5', S9, S10, S11, S12, S14, S15, S15', S16, S17, S18,
            S19, S20, S21, S26, S27', and S29
  JOURNAL   J Biol Chem 252 (24), 9071-9080 (1977)
   PUBMED   925037
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from X77953.1.
            
            On Dec 17, 2003 this sequence version replaced XM_212877.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X77953.1, FQ223930.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q35"
     gene            1..449
                     /gene="Rps15a"
                     /note="ribosomal protein S15a"
                     /db_xref="GeneID:117053"
                     /db_xref="RGD:619939"
     exon            1..142
                     /gene="Rps15a"
                     /inference="alignment:Splign:2.1.0"
     CDS             10..402
                     /gene="Rps15a"
                     /EC_number="3.6.5.3"
                     /note="40S ribosomal protein S15a"
                     /codon_start=1
                     /product="small ribosomal subunit protein uS8"
                     /protein_id="NP_446434.1"
                     /db_xref="GeneID:117053"
                     /db_xref="RGD:619939"
                     /translation="MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKH
                     GYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFI
                     VLTTSAGIMDHEEARRKHTGGKILGFFF"
     exon            143..222
                     /gene="Rps15a"
                     /inference="alignment:Splign:2.1.0"
     exon            223..308
                     /gene="Rps15a"
                     /inference="alignment:Splign:2.1.0"
     exon            309..438
                     /gene="Rps15a"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      439
                     /gene="Rps15a"
ORIGIN      
        1 accgtcacca tggtgcgaat gaatgttctg gcagatgctc tcaagagcat caacaacgcg
       61 gagaagaggg gcaaacgcca ggtcctcatc aggccgtgtt ccaaagtcat cgttcggttc
      121 ctaactgtga tgatgaagca tggctacatt ggtgaattcg agatcattga tgatcacaga
      181 gctgggaaga ttgttgtgaa cctcacagga aggttgaaca agtgtggagt tataagccct
      241 agatttgatg ttcaactcaa agacctagag aagtggcaga acaatctgct cccatcacgg
      301 cagtttggtt tcattgtgct gacgacctcg gctggcatca tggaccatga agaggcaaga
      361 cgaaaacata caggagggaa aatcctggga ttcttttttt aaatgtaaag cataaataaa
      421 aagcctctgt ggactgtgaa aaaaaaaaa
//
