LOCUS       NM_001098727            3573 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus regulation of nuclear pre-mRNA domain containing
            1B (Rprd1b), mRNA.
ACCESSION   NM_001098727 XM_001067861 XM_230798
VERSION     NM_001098727.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3573)
  AUTHORS   Ni,Z., Xu,C., Guo,X., Hunter,G.O., Kuznetsova,O.V., Tempel,W.,
            Marcon,E., Zhong,G., Guo,H., Kuo,W.W., Li,J., Young,P., Olsen,J.B.,
            Wan,C., Loppnau,P., El Bakkouri,M., Senisterra,G.A., He,H.,
            Huang,H., Sidhu,S.S., Emili,A., Murphy,S., Mosley,A.L.,
            Arrowsmith,C.H., Min,J. and Greenblatt,J.F.
  TITLE     RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain
            scaffolds for Ser5 dephosphorylation
  JOURNAL   Nat Struct Mol Biol 21 (8), 686-695 (2014)
   PUBMED   24997600
REFERENCE   2  (bases 1 to 3573)
  AUTHORS   Lu,D., Wu,Y., Wang,Y., Ren,F., Wang,D., Su,F., Zhang,Y., Yang,X.,
            Jin,G., Hao,X., He,D., Zhai,Y., Irwin,D.M., Hu,J., Sung,J.J.,
            Yu,J., Jia,B. and Chang,Z.
  TITLE     CREPT accelerates tumorigenesis by regulating the transcription of
            cell-cycle-related genes
  JOURNAL   Cancer Cell 21 (1), 92-104 (2012)
   PUBMED   22264791
REFERENCE   3  (bases 1 to 3573)
  AUTHORS   Ni,Z., Olsen,J.B., Guo,X., Zhong,G., Ruan,E.D., Marcon,E.,
            Young,P., Guo,H., Li,J., Moffat,J., Emili,A. and Greenblatt,J.F.
  TITLE     Control of the RNA polymerase II phosphorylation state in promoter
            regions by CTD interaction domain-containing proteins RPRD1A and
            RPRD1B
  JOURNAL   Transcription 2 (5), 237-242 (2011)
   PUBMED   22231121
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DY310142.1, DY565371.1, CK365545.1 and JAXUCZ010000003.1.
            
            On or before Jun 21, 2007 this sequence version replaced
            XM_230798.4, XM_001067861.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168699.1, SRR26360186.2289407.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-718               DY310142.1         1-718
            719-872             DY565371.1         495-648
            873-1416            CK365545.1         121-664
            1417-3573           JAXUCZ010000003.1  167147028-167149184
FEATURES             Location/Qualifiers
     source          1..3573
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q42"
     gene            1..3573
                     /gene="Rprd1b"
                     /gene_synonym="Crept; RGD1304782"
                     /note="regulation of nuclear pre-mRNA domain containing
                     1B"
                     /db_xref="GeneID:311591"
                     /db_xref="RGD:1304782"
     exon            1..515
                     /gene="Rprd1b"
                     /gene_synonym="Crept; RGD1304782"
                     /inference="alignment:Splign:2.1.0"
     CDS             365..1345
                     /gene="Rprd1b"
                     /gene_synonym="Crept; RGD1304782"
                     /note="cell-cycle related and expression-elevated protein
                     in tumor"
                     /codon_start=1
                     /product="regulation of nuclear pre-mRNA domain-containing
                     protein 1B"
                     /protein_id="NP_001092197.1"
                     /db_xref="GeneID:311591"
                     /db_xref="RGD:1304782"
                     /translation="MSSFSESALEKKLSELSNSQQSVQTLSLWLIHHRKHAGPIVSVW
                     HRELRKAKSNRKLTFLYLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKK
                     PLERLLNIWQERSVYGGEFIQQLKLSMEDSKSPPPKAAEEKKSLKRTFQQIQEEEDDD
                     YPGSYSPQDPSAGPLLTEELIKALQDLENAASGDATVRQKIASLPQEVQDVSLLEKIT
                     DKEAAERLSKTVDEACLLLAEYNGRLAAELEDRRQLARMLVEYTQNQKEVLSEKEKKL
                     EEYKQKLARVTQVRKELKSHIQSLPDLSLLPNVTGGLAPLPSAGDLFSTD"
     exon            516..645
                     /gene="Rprd1b"
                     /gene_synonym="Crept; RGD1304782"
                     /inference="alignment:Splign:2.1.0"
     exon            646..779
                     /gene="Rprd1b"
                     /gene_synonym="Crept; RGD1304782"
                     /inference="alignment:Splign:2.1.0"
     exon            780..892
                     /gene="Rprd1b"
                     /gene_synonym="Crept; RGD1304782"
                     /inference="alignment:Splign:2.1.0"
     exon            893..1019
                     /gene="Rprd1b"
                     /gene_synonym="Crept; RGD1304782"
                     /inference="alignment:Splign:2.1.0"
     exon            1020..1195
                     /gene="Rprd1b"
                     /gene_synonym="Crept; RGD1304782"
                     /inference="alignment:Splign:2.1.0"
     exon            1196..3573
                     /gene="Rprd1b"
                     /gene_synonym="Crept; RGD1304782"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttttcggtgt tcgaggacct ggatttgttc tctcggcctg ttcggttcga agtcctctca
       61 acaaggccca aggagagtgc tgcctcctaa gggtcgtttt cctccggctg cgaacctctc
      121 ggcgcccggc ggtggccctt gccctttgac cccgtggcgg cggggtgaga ggtcgggtgg
      181 ccatcttgtg gcggcggcgc gggcggctgt tactgcggag acctgtcccc tccccccacc
      241 tggtacccct agctgtctgt cagtcggcgg agagccgtgc agcctgtcag cggaggcctg
      301 ggctgagtgc ggtcgctttc cccgactcat cgggcggccc aggccgttcc ttaccaccgc
      361 caccatgtcc tccttctcag agtcggcgtt ggaaaagaag ctctcagagc tgagcaactc
      421 tcagcagagt gtgcagaccc tatccctgtg gctcatccac caccgcaagc acgcaggacc
      481 catcgtctcc gtgtggcacc gcgagctccg caaagccaaa tcaaatagaa agcttacttt
      541 tctctactta gcaaatgatg tcatccaaaa cagtaaaagg aaaggacctg agttcacgag
      601 agaatttgaa tctgtccttg tggatgcttt ttctcatgtt gccagagagg cagatgaagg
      661 ctgtaaaaaa cctttagaaa gattgctgaa catctggcaa gaacgaagtg tgtatggcgg
      721 cgagttcata cagcagctga agctgtctat ggaggactcc aagagccctc cccccaaagc
      781 agcggaagag aagaagtctc taaaacgaac ttttcagcag atacaggagg aggaagatga
      841 tgactaccct ggaagctact ctccccaaga tccttctgca gggcccctct tgactgagga
      901 gttaatcaaa gctttgcagg atctggaaaa tgcagcatca ggggatgcta ctgttcgaca
      961 gaagattgct tccctgcccc aggaagtgca ggatgtgtcc ctgctggaaa aaattacaga
     1021 caaagaggca gctgaacgtc tttcaaaaac agtagatgaa gcatgtctgt tactagcgga
     1081 atataacggg cgcctggcag cggaactgga agaccggcgc cagctggctc ggatgctggt
     1141 ggagtacacc cagaaccaaa aagaggtttt gtcagaaaag gagaaaaagc tagaagaata
     1201 taaacagaag cttgctcgag taacccaggt ccgcaaggaa ctcaagtccc acattcagag
     1261 cttgccggac ctctcactgc tgcctaatgt cacagggggc ctggcacctc tgccctctgc
     1321 tggtgacctc ttttcaactg actaagacag gtatcatgct ccaggttccc gtgtgtgcca
     1381 gaaaaaagaa gcgagtcact gttggagaca gtcccctgcc ccggctcctt ctcttcagcc
     1441 agcatctgcc tcagtaatga agcggggaac tctgacttct cactctcctc cggctccctc
     1501 ctgagcatgg ttcagaaccg tgcagatgga ctcagttttg attcgtattt gctaagaata
     1561 cagactcttc ctcccactca cgttctcttc caccgctgcg tttccattct tagctctctt
     1621 acacccacaa gccatgaaaa tcatgtgtac ttctggaagc ttttgagata agcttgcctc
     1681 ggtgacagca catgtcatgg aagtctgagc tggccttgac caggttcaga acaggcttcc
     1741 agtgagggct gggctgcagg aattggcttt cctggccacc ctctgctcac aaggtcggca
     1801 gcacagcttg ccacaaagag attgccaaat tgctgacatc tcccgacctg agcacgtcta
     1861 gtagagaggg taggtgtgtg tgtctgtgaa cgttctagag aatctgcaat aaggttcaaa
     1921 gctgatctga gacctagagt acaggtacag agtggcaggg gtcacgagtc gttgcctggc
     1981 ttctctccac agccttccct gccacacttc tcaaggttcc cggtttcaga gcaccttcct
     2041 aaagcagggc ccctgcccct ggtgctggga agggagctgt tgggacagtg cgccccgaat
     2101 agcgcacccc aggctgatgc acctccacag cccacagctg gagtccgggc cttccccctc
     2161 ccactggggc tggagcttac agttagagca ccatgtggac atacatcccc agcatggcgg
     2221 ctaaccttga acatctacag ctaggacact gagcctgcca gcatcacgct gctctctgca
     2281 tccatgctcc cacgcagaga ggagaactca tacaaagacc tctcctccag caggggaagg
     2341 aacagaggga gactgattgg ggttttaatt ccattatcat gccagctgac cttgtgaccg
     2401 aatgatgtgg ttgagatttt tacgtctcgt aaagattggg cctgcacctg gaagtgattg
     2461 taatctggca ggcttgtttg acattggaaa gggcagaaac ccttttgtcc tcctagtgta
     2521 ataggaattg ttgcctggag ctgaagtcca aaagctgtaa gaaggaattc agtgaaggga
     2581 ccttgagaag cttcattact ttaagttgct gttttcagga tcaccaaaaa agcacacatc
     2641 gttttttaca tgttaaagca aacctgtgtc attgtaggca ggcttcagtc tgagaagcca
     2701 ccctgcctgc tatgaggtga gactcagttc cactgtgtcc agcctggtca ctgtggaaac
     2761 tgttatcaca tcgaatgcag gctgctgttt gcttgttcac tctgcctctt ctgtcagcat
     2821 ccttttctcc agaggctaca ggacagcact gacttgggtg aaatcccgtc tctgctgcgg
     2881 aacacctccc cacacacagc gccactatac tgtcacgtgc acaccatcct caactcctcc
     2941 cccagacact gctttcccac gagacagaca aaagattgta gcggctctgc tctgatgaca
     3001 acttgatgga gtcggctcag tgctgtgttt tattctttgg agtctgacag caatcagtgt
     3061 gtaactctta gagcaggatc aagacacgaa ccagtagcga ttatgtaaat gaatgtgttg
     3121 gtctcttaac accagttgct agcagacttc tgtaaggaag ttagttttgt tttaatgaaa
     3181 tgcttcagtt ttttaatctt tcttgttgtc tgcctctcct tcctcccctc cctcagtctc
     3241 ccaactgtgt gcttacttcc cttgtttaac ttaagtgaaa cttttgtccc tgagagttga
     3301 tctggtgggt ggggtgggtg acttctggtt ttgtgtttct ttaggggatc cataggcctc
     3361 aaggatcttt cctttagggt catattcctc agaaagtctt cagtctttct ttgtttttgt
     3421 tttgtttttc ctaaaggata tttttaaagc ttaaatttgt atattaattt aggactttat
     3481 ttagaagtat aggctgccat tggtgacagc agtatattct gaaatgtctc atagatatat
     3541 atttttgaat aaagatggtg ttgttgaaca aca
//
