LOCUS       NM_001305179            4343 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus regulation of nuclear pre-mRNA domain containing
            1A (Rprd1a), mRNA.
ACCESSION   NM_001305179 XM_008772003 XM_008774105
VERSION     NM_001305179.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4343)
  AUTHORS   Ni,Z., Xu,C., Guo,X., Hunter,G.O., Kuznetsova,O.V., Tempel,W.,
            Marcon,E., Zhong,G., Guo,H., Kuo,W.W., Li,J., Young,P., Olsen,J.B.,
            Wan,C., Loppnau,P., El Bakkouri,M., Senisterra,G.A., He,H.,
            Huang,H., Sidhu,S.S., Emili,A., Murphy,S., Mosley,A.L.,
            Arrowsmith,C.H., Min,J. and Greenblatt,J.F.
  TITLE     RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain
            scaffolds for Ser5 dephosphorylation
  JOURNAL   Nat Struct Mol Biol 21 (8), 686-695 (2014)
   PUBMED   24997600
REFERENCE   2  (bases 1 to 4343)
  AUTHORS   Ni,Z., Olsen,J.B., Guo,X., Zhong,G., Ruan,E.D., Marcon,E.,
            Young,P., Guo,H., Li,J., Moffat,J., Emili,A. and Greenblatt,J.F.
  TITLE     Control of the RNA polymerase II phosphorylation state in promoter
            regions by CTD interaction domain-containing proteins RPRD1A and
            RPRD1B
  JOURNAL   Transcription 2 (5), 237-242 (2011)
   PUBMED   22231121
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000018.1.
            
            On or before Feb 27, 2015 this sequence version replaced
            XM_008772003.1, XM_008774105.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments and orthologous data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643294.56877.1,
                                           SRR26643298.72855.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN12840105,
                                           SAMN12840106 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-301               JAXUCZ010000018.1  16113787-16114087   c
            302-431             JAXUCZ010000018.1  16091513-16091642   c
            432-538             JAXUCZ010000018.1  16090322-16090428   c
            539-636             JAXUCZ010000018.1  16090076-16090173   c
            637-763             JAXUCZ010000018.1  16089172-16089298   c
            764-939             JAXUCZ010000018.1  16088893-16089068   c
            940-4343            JAXUCZ010000018.1  16066169-16069572   c
FEATURES             Location/Qualifiers
     source          1..4343
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18p12"
     gene            1..4343
                     /gene="Rprd1a"
                     /gene_synonym="P15rs; RGD1307374"
                     /note="regulation of nuclear pre-mRNA domain containing
                     1A"
                     /db_xref="GeneID:291736"
                     /db_xref="RGD:1307374"
     exon            1..301
                     /gene="Rprd1a"
                     /gene_synonym="P15rs; RGD1307374"
                     /inference="alignment:Splign:2.1.0"
     CDS             151..1089
                     /gene="Rprd1a"
                     /gene_synonym="P15rs; RGD1307374"
                     /note="cyclin-dependent kinase 2B-inhibitor-related
                     protein"
                     /codon_start=1
                     /product="regulation of nuclear pre-mRNA domain-containing
                     protein 1A"
                     /protein_id="NP_001292108.1"
                     /db_xref="GeneID:291736"
                     /db_xref="RGD:1307374"
                     /translation="MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVW
                     ERELRKAKPNRKLTFLYLANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSSETDESCKK
                     HLGRVLSIWEERSVYENDVLEQLKHALYGDKKTRKRTYEQIKVDENENCSSLGSPSEP
                     PQTLDLVRALQDLENAASGDAAVHQRIASLPVEVQEVSLLEKITDKESGERLSKMVED
                     ACMLLADYNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVR
                     KELRARIQSLPDLSRLPNVTGSHMHLPFAGDIYSED"
     exon            302..431
                     /gene="Rprd1a"
                     /gene_synonym="P15rs; RGD1307374"
                     /inference="alignment:Splign:2.1.0"
     exon            432..538
                     /gene="Rprd1a"
                     /gene_synonym="P15rs; RGD1307374"
                     /inference="alignment:Splign:2.1.0"
     exon            539..636
                     /gene="Rprd1a"
                     /gene_synonym="P15rs; RGD1307374"
                     /inference="alignment:Splign:2.1.0"
     exon            637..763
                     /gene="Rprd1a"
                     /gene_synonym="P15rs; RGD1307374"
                     /inference="alignment:Splign:2.1.0"
     exon            764..939
                     /gene="Rprd1a"
                     /gene_synonym="P15rs; RGD1307374"
                     /inference="alignment:Splign:2.1.0"
     exon            940..4343
                     /gene="Rprd1a"
                     /gene_synonym="P15rs; RGD1307374"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctagattgc gaccagcctc ggactcgggg gtggtagtgg tgagggcgtg gggaagggtg
       61 gggtgtgggg gcgaggcggc gacgagggcg gcgacactct cctcccctca gctccacggc
      121 gtgggacggc gcgaacgtgg ttttggaggg atgtccgcct tctctgaggc ggcgctggag
      181 aagaagctgt ccgagttgag caactcgcag cagagcgtgc agaccctgtc cctgtggctc
      241 atccaccatc gcaaacactc gcggcccatc gtcacggtgt gggagcggga gctacgcaaa
      301 gccaaaccca acaggaagct tacttttctc tacttggcca atgatgtcat tcaaaacagc
      361 aaaaggaagg ggccagagtt cacaaaagat tttgcaccag taatagtgga ggcattcaag
      421 catgtttcaa gtgaaactga tgaaagctgt aagaagcacc ttgggagagt attatccatt
      481 tgggaagagc ggtctgttta tgaaaacgat gtattagaac aacttaagca cgctctgtat
      541 ggagataaga agacgaggaa gaggacttat gagcaaataa aggtggatga gaatgaaaat
      601 tgttcctctc tagggtcccc aagtgaacca ccacagactc tcgaccttgt tagagcatta
      661 caagatttag aaaatgcagc ctcaggtgat gcagcagtcc atcaaaggat agcttctttg
      721 cctgttgaag ttcaagaagt atccctgctc gagaaaataa cagataaaga atctggagaa
      781 aggctttcta agatggtgga agacgcttgt atgctgctgg cagactataa tggcagactg
      841 gcagcagaaa tagacgacag aaagcaactc actcggatgt tagcggactt tcttcgttgt
      901 caaaaggaag cccttgcaga gaaagaacat aaattggaag aatacaagcg caagttagcc
      961 cgagtttcct tggtacgaaa agaactcaga gcccggatcc agagcctgcc agatttatct
     1021 cgtttgccca atgtcactgg cagtcacatg cacctgccct ttgctgggga catctacagt
     1081 gaagactgat ggccagtctc ctccagggcc aggactttgc cagacatgga gacaggttag
     1141 gtgaatagtc ctgtagagtt atttttgtac attgttgaga gaatggtact aacacaagaa
     1201 atgacaaggc agtataaaat gtctaaaatg ttggtttgtt ttactatttt attggtgagt
     1261 taacacgact tagttaaaac caagtgattt ctgtgtatta atgaacttaa tgattatttt
     1321 caaaatatct tttgtaaatt tttttttgat ccaaggcctt gtgaaaaatt ccatgtttct
     1381 atttcttcat gtattttcaa ttatttttct ttattttttt tcagtatcta atcactgtac
     1441 actctctaat tcctaatgag aagaactgat caggagctga tgtgagactg tttttgggat
     1501 cgttaggact tgattataga agagacttaa gtgtttgaac ttcaccttta ctcttgccac
     1561 caaatactgg ttctgtgtgt cctcatgcct tttgagtttt aacgctagac atggatgcca
     1621 tgtgcagggt caaattaaag cctagagaat gtttccccga tagcactata gtagttccat
     1681 cccaaatgcc atcccagaat aagaggcctg ttaaatagag tcccttgatc acactattta
     1741 gaactaagtg cagttaatgc tttgagaatg ttgcaagttc tgacatccta ccaagaggac
     1801 aactccaggc ctacagctga ctgcttctgt caggtcagtt ttctttacat cagatccctt
     1861 taacaaaaca ccagccgtgg ggaggaaaga aaggacgcat cagatggcga catgcttaat
     1921 ccctgtgatg taatgtaaac aatagctctt agcttgatta gctcaacaac tcagtatcca
     1981 taatgtccaa ttaagttgcc cggaacactt tatttccgta aggttttgaa tgactgtata
     2041 ttttggaatt acgcaatgct gtactacagg gtagatgtag tgagttttat atttgtatgt
     2101 ttacagatgt aaatacacag caaatgtacc tgtaccttta cttgaacctg gtgtgggaga
     2161 gcagttgcat gctcctctcc agctttcttc taagttacat tgtgagcctg caggtttgtg
     2221 tttcataacg acagaagggg gatatttttc tcctttattg ctttgcattt ctcatgtaat
     2281 cggagtcaaa gtaaatagtt aatagaacac tttttaaatt tcacaggcca attatactca
     2341 ctattctgaa cggcttcact ctttctttct cagtattcga ggttatagtt gaagtgaatt
     2401 tacatgtgaa gaaatgacag tagatttggg aacagtgctt taaacactga cctctcttca
     2461 aacagagtta catgtataac atcacccatc ccctgcatgt cctgtcttcc aaggatttag
     2521 acaacatttg ggagttagga cacatttcct cacagaactt agagctgttc tctgtgcaca
     2581 ctgctgaagc tcaacgggga gccaaaacca cctgaccacg gatacactca taacgtgggc
     2641 aacgagtggc tcaagcacgt cctgagcagc atttgtctgt cacagtaagg ggtctgtgtg
     2701 cagcagcaag gtcctcctca tgctggggtg tctgccagtg ctgctgtcct ttcctagggg
     2761 gtaggggtgg aagaaaggac tcagcaggag ggtgcacgga tgctgcacat gacgcaccct
     2821 gactatgcct gttttgaaag tatgccaagt aagttagttt ttgttgttga tgtctttgaa
     2881 agcaaaagct ttgtgtgtta acttattttc agtatcttga acttatttat gatttgctga
     2941 cacagtgatt tatccatcta aaaatagata cttttccatt taaaactaat ttataaatgg
     3001 tatactcttg ggaagatata aaatctttta gaagtttcct gaatattttc accatgaaga
     3061 cagacttaga tactcttttg atgccactat ctgatctaaa tatttatgat aaatgtatta
     3121 tttttttaaa gagcgtgatg agatctgtga ttaaatgcta gtactcaaaa cccgaatccc
     3181 ccaaacttca agttgttggt tagctcgcta cctgaataca aactgtacag tctgttctag
     3241 aagtcaggtt ctcagcctca ggagattgcc ttcctttcta aaaggaagat gaacttaatg
     3301 ggcttaaact gggcgtggtg gtgcatgcct ttaatctctg tacttggggg gcagaggtag
     3361 gaagatccct gtgagtttaa ggccagtctg ttctgtagag tgagacccat gccattaatt
     3421 acatggtgag accctgcatt aagaaaaaga aataagaatg ggcttaggtg aggggtataa
     3481 aataccaaac tctaaatcat gcacagtttc tctaccgtgt acctgaggta aattacaagt
     3541 atgagagcaa cctggcctgg ccctcaaggg aaagcgtgtc tcattgtagc aaggtcctgt
     3601 gctgtgattg gacaccattc ctcttttctc cacaaacagt gcagagagct gtcggagtgg
     3661 caatgtgagc agattccccg gtgctccctc tgctcctaca acactacagt aagtaaatga
     3721 actatatggg gagctgggag cctggaaatg agctgtgctc tatagccagc cttccctgag
     3781 gaaagccacc ccacctagct gttgtgacag ctgctcacag cattctgaat cagggttttc
     3841 tctaagaaat cctttagcat caacaaagtc taggatgatc cagccatcat gattgtcagt
     3901 tcagagaatg ttgtctgctg ccactgtcat gagtagcttc atggtgtgtg gctcatgtac
     3961 ggtctgagaa gtctggagag gacagtgact gggaaggtag gagggccttc ctgaattccc
     4021 actctgaaat ggacaggatg tgaagtaacg taaagtccca cattgcttta ctagctgtta
     4081 ggagttactc ctaaagatga gccctgcttc tcagttgtgc cagaaaaggc ttttaacagt
     4141 gtgaattcag ttcttctctg tacagaaagg gaacactggg ttactcaatg gagttgttta
     4201 tacacagcat tcgttgccat cgagtctcag atggcaggag cacatgagaa ggggattctc
     4261 cgtcttttat aaaccctttt ctttggctgt atctgatgac agtgtaagat cttaataaag
     4321 ttttgtgttc tttttgaaga gtt
//
