LOCUS       NM_001191083            1444 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus ribonuclease P/MRP subunit p30 (Rpp30), mRNA.
ACCESSION   NM_001191083 XM_001063377
VERSION     NM_001191083.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1444)
  AUTHORS   Wu,J., Niu,S., Tan,M., Huang,C., Li,M., Song,Y., Wang,Q., Chen,J.,
            Shi,S., Lan,P. and Lei,M.
  TITLE     Cryo-EM Structure of the Human Ribonuclease P Holoenzyme
  JOURNAL   Cell 175 (5), 1393-1404 (2018)
   PUBMED   30454648
REFERENCE   2  (bases 1 to 1444)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 1444)
  AUTHORS   Lai,L.B., Vioque,A., Kirsebom,L.A. and Gopalan,V.
  TITLE     Unexpected diversity of RNase P, an ancient tRNA processing enzyme:
            challenges and prospects
  JOURNAL   FEBS Lett 584 (2), 287-296 (2010)
   PUBMED   19931535
  REMARK    Review article
REFERENCE   4  (bases 1 to 1444)
  AUTHORS   Welting,T.J., Kikkert,B.J., van Venrooij,W.J. and Pruijn,G.J.
  TITLE     Differential association of protein subunits with the human RNase
            MRP and RNase P complexes
  JOURNAL   RNA 12 (7), 1373-1382 (2006)
   PUBMED   16723659
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Jul 17, 2010 this sequence version replaced XM_001063377.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FN805737.1, SRR26643429.5476.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-90                JAXUCZ010000001.1  243198713-243198802
            91-146              JAXUCZ010000001.1  243200088-243200143
            147-203             JAXUCZ010000001.1  243201736-243201792
            204-278             JAXUCZ010000001.1  243202158-243202232
            279-350             JAXUCZ010000001.1  243204162-243204233
            351-440             JAXUCZ010000001.1  243209665-243209754
            441-557             JAXUCZ010000001.1  243216808-243216924
            558-587             JAXUCZ010000001.1  243217445-243217474
            588-625             JAXUCZ010000001.1  243217853-243217890
            626-705             JAXUCZ010000001.1  243218529-243218608
            706-1444            JAXUCZ010000001.1  243220821-243221559
FEATURES             Location/Qualifiers
     source          1..1444
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q53"
     gene            1..1444
                     /gene="Rpp30"
                     /note="ribonuclease P/MRP subunit p30"
                     /db_xref="GeneID:685332"
                     /db_xref="RGD:1595116"
     exon            1..90
                     /gene="Rpp30"
                     /inference="alignment:Splign:2.1.0"
     CDS             9..815
                     /gene="Rpp30"
                     /EC_number="3.1.26.5"
                     /note="ribonuclease P/MRP 30 subunit"
                     /codon_start=1
                     /product="ribonuclease P protein subunit p30"
                     /protein_id="NP_001178012.1"
                     /db_xref="GeneID:685332"
                     /db_xref="RGD:1595116"
                     /translation="MAAFADLDLRAGSDLKALRGLVETAAHLGYSVVAINHIVDFKEK
                     KREIEKPVAVSELFTTLPIVQGKSRPIKILTRLTIIVTDPSHCNVLRATSSRVRLYDI
                     VAVFPKTEKLFHVACTHLDVDLVCITVTEKLPFYFKRPPINVAIERGLGFELVYGPAI
                     RDATMRRYTISNALNLMQICKGKNVILSSAAERPLEIRGPYDVANLGLLFGLSENEGK
                     AAVSTNCRAAFLHGETRKTAFGIISTVKKPRSSEAEDESLPACKKAKHEG"
     exon            91..146
                     /gene="Rpp30"
                     /inference="alignment:Splign:2.1.0"
     exon            147..203
                     /gene="Rpp30"
                     /inference="alignment:Splign:2.1.0"
     exon            204..278
                     /gene="Rpp30"
                     /inference="alignment:Splign:2.1.0"
     exon            279..350
                     /gene="Rpp30"
                     /inference="alignment:Splign:2.1.0"
     exon            351..440
                     /gene="Rpp30"
                     /inference="alignment:Splign:2.1.0"
     exon            441..557
                     /gene="Rpp30"
                     /inference="alignment:Splign:2.1.0"
     exon            558..587
                     /gene="Rpp30"
                     /inference="alignment:Splign:2.1.0"
     exon            588..625
                     /gene="Rpp30"
                     /inference="alignment:Splign:2.1.0"
     exon            626..705
                     /gene="Rpp30"
                     /inference="alignment:Splign:2.1.0"
     exon            706..1444
                     /gene="Rpp30"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgtcagcat ggcggcgttc gcagatttgg atctaagagc gggctcagac ctgaaggctc
       61 tgcgcggact cgtggagacc gctgctcacc tgggatactc agttgttgcc atcaatcaca
      121 ttgttgactt taaggaaaag aaacgggaaa ttgaaaagcc agtagcagtt tctgagctct
      181 tcacaacttt accaattgta cagggaaaat caagaccaat taaaatttta actagattga
      241 caattatagt tacagatccg tctcactgta atgttttgag agcaacttct tcaagggtcc
      301 ggctgtatga tattgttgca gtgtttccaa agacagaaaa actttttcat gttgcttgta
      361 cacacttaga tgtggattta gtctgtatca ccgtaacaga gaaattacca ttttacttca
      421 aaagacctcc tattaatgtg gcgatcgagc gaggcctggg ctttgagctg gtctatggtc
      481 ctgctatcag agacgcaacc atgagaaggt acacaatctc caatgccctc aatctgatgc
      541 agatctgcaa aggaaagaac gtaattctgt ccagtgctgc agaaaggcct ttggaaataa
      601 gaggaccata tgacgtggcc aacttagggc tgctgttcgg gctgtccgaa aatgaaggca
      661 aggctgccgt gtccacaaac tgccgagctg catttctcca tggagaaact aggaaaactg
      721 cttttggaat tatttctaca gtgaagaagc cccggtcatc agaagcagag gatgaatctc
      781 ttccagcgtg caagaaagct aaacatgagg gctgaggaga cagcctgagt ctccatcacg
      841 ctgctcctcc cctcacagct catcagtcac tgcaaataca ctccgctcgg ctgacgtttt
      901 cactaaacta gaaaccaagt ctataaaaac agcttcatat tcagacatta aaacagcaaa
      961 taaaacccag tgaagcattt ttaaagacta acgattaatt tagatatact tttaaaagaa
     1021 aaactattac ccttcatgtg agtaatgaat agcagtaggt gcactgaaac aagatgtctc
     1081 gatattgtaa aatattgaaa aataataaat taatgttttt tgttcttggt acatatggat
     1141 ttgtaacttt tactatccca aaaagtggtt attttgaaga cttaagctct gttgtgcagg
     1201 tgactttaac caactgatta tgttttaagc tctttgatgt cctgctcggg ttaaagcctt
     1261 tctgaaggcc tcctggacct gtgaaaggag aagggcactc acaagagttg cttatcccct
     1321 ctatgtgctc cctcctgcct tcaagttgtc ctgaagacat attcctccct ttagttagac
     1381 atcattcagt agctaatact gattttccta gttgctatag gtttaaagca tttggctcaa
     1441 aaaa
//
