LOCUS       NM_001012124            1405 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus ribonuclease P and MRP subunit p25 (Rpp25), mRNA.
ACCESSION   NM_001012124 XM_236286
VERSION     NM_001012124.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1405)
  AUTHORS   Wu,J., Niu,S., Tan,M., Huang,C., Li,M., Song,Y., Wang,Q., Chen,J.,
            Shi,S., Lan,P. and Lei,M.
  TITLE     Cryo-EM Structure of the Human Ribonuclease P Holoenzyme
  JOURNAL   Cell 175 (5), 1393-1404 (2018)
   PUBMED   30454648
REFERENCE   2  (bases 1 to 1405)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 1405)
  AUTHORS   Huang,H.S., Cheung,I. and Akbarian,S.
  TITLE     RPP25 is developmentally regulated in prefrontal cortex and
            expressed at decreased levels in autism spectrum disorder
  JOURNAL   Autism Res 3 (4), 153-161 (2010)
   PUBMED   20632321
REFERENCE   4  (bases 1 to 1405)
  AUTHORS   Lai,L.B., Vioque,A., Kirsebom,L.A. and Gopalan,V.
  TITLE     Unexpected diversity of RNase P, an ancient tRNA processing enzyme:
            challenges and prospects
  JOURNAL   FEBS Lett 584 (2), 287-296 (2010)
   PUBMED   19931535
  REMARK    Review article
REFERENCE   5  (bases 1 to 1405)
  AUTHORS   Welting,T.J., Kikkert,B.J., van Venrooij,W.J. and Pruijn,G.J.
  TITLE     Differential association of protein subunits with the human RNase
            MRP and RNase P complexes
  JOURNAL   RNA 12 (7), 1373-1382 (2006)
   PUBMED   16723659
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC087592.1.
            
            On Feb 11, 2005 this sequence version replaced XM_236286.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC087592.1, CO385472.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1405
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..1405
                     /gene="Rpp25"
                     /note="ribonuclease P and MRP subunit p25"
                     /db_xref="GeneID:315705"
                     /db_xref="RGD:1305290"
     exon            1..1381
                     /gene="Rpp25"
                     /inference="alignment:Splign:2.1.0"
     CDS             186..785
                     /gene="Rpp25"
                     /EC_number="3.1.26.5"
                     /note="ribonuclease P/MRP 25 subunit; RNase P protein
                     subunit p25; ribonuclease P 25 subunit"
                     /codon_start=1
                     /product="ribonuclease P protein subunit p25"
                     /protein_id="NP_001012124.1"
                     /db_xref="GeneID:315705"
                     /db_xref="RGD:1305290"
                     /translation="MENFRKVRSEEAPAGDGDEGGSPSSGPFADLAPGAVHMRVKEGS
                     KIRNLLAFATASMAQPATRAIVFSGCGRATTKTVTCAEILKRRLAGLHQVTRLRYRSV
                     REVWQSLPPGPTPGQTPSDPAASLSVLKNVPSLAILLSKDALDPRQLGYQPPNLSPGP
                     SSPPTVSTSKRSLGESAAGEGTAKRSQPEPEAENEDRTA"
ORIGIN      
        1 gtagaacagc actaccctgt agaagtctgg gctgaagact ccgcgttccc tgctcaccct
       61 ccagctttca ctcggtgcca gcatcccaat tcctgccggc cctcgcccgg cacgacccgc
      121 ggccatgcag ccccgggctt gaggcggccc catggcaaaa cctgcgatcc cagcgacgac
      181 ggcgcatgga gaacttccgt aaggtgcgct cggaggaggc gccggcgggg gacggtgatg
      241 agggtggcag cccgagctct ggcccttttg cagatctggc gcctggtgct gtacacatgc
      301 gggtcaagga gggcagcaag atccgcaacc tgctggcctt cgccaccgct agcatggcgc
      361 agccagccac gcgcgccatc gtcttcagcg gctgcggccg ggccaccacc aagaccgtca
      421 cgtgcgccga gattctcaag cgccgcctgg cgggcttaca ccaggtcacg cggctgcgct
      481 acaggagcgt gcgcgaggtg tggcagagcc tcccgcctgg gcccacaccg ggtcagacgc
      541 ccagcgatcc ggccgccagt ctcagtgtac ttaagaatgt accgagcctc gccatcctac
      601 tttcaaagga cgcactggat ccacgacagc ttggctacca gcccccgaac ctcagtcctg
      661 gtccttcgtc ccctcctacc gtgtcgacgt ccaagaggag cctgggggaa tctgcagctg
      721 gagaaggcac agctaagcgg tctcagcctg agccagaggc tgagaatgag gaccggactg
      781 cctgagaatt ctcgcctctg aaccacctag actggatctt atatcttcaa cacacctaca
      841 tccacatgca cccttcctac ctgggtttta aggggcccat gttcctgaat attggtcctc
      901 aaaatgacaa cgcggatccc aaggcgacag gagagggagc tcaagaatta caagagagga
      961 ttcttgaagt ccgaggaaaa ctttgtggga catgttgcca gaagccacag aacaccaccc
     1021 acaccttttc taggccatct tttttaggga agcctggtgg gtagtgggac tcttgagctt
     1081 tcttggggac ccagacgtta aaagcaccca gtgtgcatgg aggctgacag ttgaggcttt
     1141 aaaaaccgtc cttgttgtta actgagagca ggagctgtga agctgtttcc ttgagggtga
     1201 ccaagttgaa aatgtctgga ccctgttctg cccacccaca ccctagcata ttccttttag
     1261 cttcccccca ccctcacccc tgttgcatgg tggcagagac gggacccagg aggaaacttg
     1321 ccatgcttcc tcccctgagt cctgctggag tattgcttcc aataaaacaa acatgaaaat
     1381 gaaaaaaaaa aaaaaaaaaa aaaaa
//
