LOCUS       NM_001002831             499 bp    mRNA    linear   ROD 23-APR-2024
DEFINITION  Rattus norvegicus ribonuclease P/MRP subunit p21 (Rpp21), mRNA.
ACCESSION   NM_001002831 XM_579092
VERSION     NM_001002831.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 499)
  AUTHORS   Wu,J., Niu,S., Tan,M., Huang,C., Li,M., Song,Y., Wang,Q., Chen,J.,
            Shi,S., Lan,P. and Lei,M.
  TITLE     Cryo-EM Structure of the Human Ribonuclease P Holoenzyme
  JOURNAL   Cell 175 (5), 1393-1404 (2018)
   PUBMED   30454648
REFERENCE   2  (bases 1 to 499)
  AUTHORS   Lai,L.B., Vioque,A., Kirsebom,L.A. and Gopalan,V.
  TITLE     Unexpected diversity of RNase P, an ancient tRNA processing enzyme:
            challenges and prospects
  JOURNAL   FEBS Lett 584 (2), 287-296 (2010)
   PUBMED   19931535
  REMARK    Review article
REFERENCE   3  (bases 1 to 499)
  AUTHORS   Han,A., Song,Z., Tong,C., Hu,D., Bi,X., Augenlicht,L.H. and Yang,W.
  TITLE     Sulindac suppresses beta-catenin expression in human cancer cells
  JOURNAL   Eur J Pharmacol 583 (1), 26-31 (2008)
   PUBMED   18291362
REFERENCE   4  (bases 1 to 499)
  AUTHORS   Welting,T.J., Kikkert,B.J., van Venrooij,W.J. and Pruijn,G.J.
  TITLE     Differential association of protein subunits with the human RNase
            MRP and RNase P complexes
  JOURNAL   RNA 12 (7), 1373-1382 (2006)
   PUBMED   16723659
REFERENCE   5  (bases 1 to 499)
  AUTHORS   Hurt,P., Walter,L., Sudbrak,R., Klages,S., Muller,I., Shiina,T.,
            Inoko,H., Lehrach,H., Gunther,E., Reinhardt,R. and Himmelbauer,H.
  TITLE     The genomic sequence and comparative analysis of the rat major
            histocompatibility complex
  JOURNAL   Genome Res 14 (4), 631-639 (2004)
   PUBMED   15060004
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BX883050.1.
            
            On Apr 19, 2005 this sequence version replaced XM_579092.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ211619.1, CB546156.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..499
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..499
                     /gene="Rpp21"
                     /gene_synonym="Flj22638"
                     /note="ribonuclease P/MRP subunit p21"
                     /db_xref="GeneID:406230"
                     /db_xref="RGD:1303090"
     exon            1..64
                     /gene="Rpp21"
                     /gene_synonym="Flj22638"
                     /inference="alignment:Splign:2.1.0"
     CDS             8..460
                     /gene="Rpp21"
                     /gene_synonym="Flj22638"
                     /EC_number="3.1.26.5"
                     /note="ribonuclease P 21kDa subunit; ribonuclease P 21
                     subunit; ribonuclease P/MRP 21 subunit"
                     /codon_start=1
                     /product="ribonuclease P protein subunit p21"
                     /protein_id="NP_001002831.1"
                     /db_xref="GeneID:406230"
                     /db_xref="RGD:1303090"
                     /translation="MAGQVKDREAFQRLNFLYQAAHCVLSQNPENQALARFYCHTEKT
                     IAKRLVLRQDPSVKRTLCRDCSSLLIPGLTCTQRQRRRKGQRWTVQTCLTCQRSQRFL
                     NDPKHLLWGDRPEAQLENQADFKPSEPLPNIADLSKENVQTQALNTTE"
     exon            65..165
                     /gene="Rpp21"
                     /gene_synonym="Flj22638"
                     /inference="alignment:Splign:2.1.0"
     exon            166..248
                     /gene="Rpp21"
                     /gene_synonym="Flj22638"
                     /inference="alignment:Splign:2.1.0"
     exon            249..374
                     /gene="Rpp21"
                     /gene_synonym="Flj22638"
                     /inference="alignment:Splign:2.1.0"
     exon            375..499
                     /gene="Rpp21"
                     /gene_synonym="Flj22638"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gacactcatg gcgggccaag tgaaagaccg ggaggccttc cagagactca acttccttta
       61 ccaggctgca cactgcgtcc tctctcagaa ccccgagaac caggcactgg ctaggtttta
      121 ctgccacaca gagaagacca tcgcgaagcg gctggtccta cggcaggacc cctctgtgaa
      181 gaggacgctc tgtcgcgact gctcctctct cctcatccct ggcctcacct gcacgcagcg
      241 ccagagacgc cgaaagggac aacgctggac agtacagacc tgtctgacat gccagcgaag
      301 ccagcggttc ctcaatgacc ccaagcatct cctctggggt gaccggcctg aagcccagtt
      361 ggaaaatcag gcggatttca aaccgtcaga gcccctgcca aacatagctg acctttctaa
      421 ggagaacgtg cagactcagg ctttaaacac cactgaatga actcatccat tttccagata
      481 aataaagttg agttgtttg
//
