LOCUS       NM_001108372            1870 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus ribonuclease P/MRP subunit p14 (Rpp14),
            transcript variant 1, mRNA.
ACCESSION   NM_001108372 XM_001060859 XM_341295
VERSION     NM_001108372.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1870)
  AUTHORS   Wu,J., Niu,S., Tan,M., Huang,C., Li,M., Song,Y., Wang,Q., Chen,J.,
            Shi,S., Lan,P. and Lei,M.
  TITLE     Cryo-EM Structure of the Human Ribonuclease P Holoenzyme
  JOURNAL   Cell 175 (5), 1393-1404 (2018)
   PUBMED   30454648
REFERENCE   2  (bases 1 to 1870)
  AUTHORS   Andreev,D.E., O'Connor,P.B., Zhdanov,A.V., Dmitriev,R.I.,
            Shatsky,I.N., Papkovsky,D.B. and Baranov,P.V.
  TITLE     Oxygen and glucose deprivation induces widespread alterations in
            mRNA translation within 20 minutes
  JOURNAL   Genome Biol 16 (1), 90 (2015)
   PUBMED   25943107
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1870)
  AUTHORS   Lai,L.B., Vioque,A., Kirsebom,L.A. and Gopalan,V.
  TITLE     Unexpected diversity of RNase P, an ancient tRNA processing enzyme:
            challenges and prospects
  JOURNAL   FEBS Lett 584 (2), 287-296 (2010)
   PUBMED   19931535
  REMARK    Review article
REFERENCE   4  (bases 1 to 1870)
  AUTHORS   Welting,T.J., Kikkert,B.J., van Venrooij,W.J. and Pruijn,G.J.
  TITLE     Differential association of protein subunits with the human RNase
            MRP and RNase P complexes
  JOURNAL   RNA 12 (7), 1373-1382 (2006)
   PUBMED   16723659
REFERENCE   5  (bases 1 to 1870)
  AUTHORS   Shultz,M.A., Zhang,L., Gu,Y.Z., Baker,G.L., Fannuchi,M.V.,
            Padua,A.M., Gurske,W.A., Morin,D., Penn,S.G., Jovanovich,S.B.,
            Plopper,C.G. and Buckpitt,A.R.
  TITLE     Gene expression analysis in response to lung toxicants: I.
            Sequencing and microarray development
  JOURNAL   Am J Respir Cell Mol Biol 30 (3), 296-310 (2004)
   PUBMED   12947022
REFERENCE   6  (bases 1 to 1870)
  AUTHORS   Jarrous,N., Wolenski,J.S., Wesolowski,D., Lee,C. and Altman,S.
  TITLE     Localization in the nucleolus and coiled bodies of protein subunits
            of the ribonucleoprotein ribonuclease P
  JOURNAL   J Cell Biol 146 (3), 559-572 (1999)
   PUBMED   10444065
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000015.1.
            
            On Dec 5, 2020 this sequence version replaced NM_001108372.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Both variants 1 and 2 encode the same protein.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CO566101.1, SRR22399484.625482.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760386,
                                           SAMN12840107 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-195               JAXUCZ010000015.1  19278003-19278197   c
            196-348             JAXUCZ010000015.1  19275920-19276072   c
            349-436             JAXUCZ010000015.1  19274489-19274576   c
            437-521             JAXUCZ010000015.1  19274286-19274370   c
            522-598             JAXUCZ010000015.1  19271205-19271281   c
            599-677             JAXUCZ010000015.1  19270355-19270433   c
            678-1870            JAXUCZ010000015.1  19268025-19269217   c
FEATURES             Location/Qualifiers
     source          1..1870
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p14"
     gene            1..1870
                     /gene="Rpp14"
                     /note="ribonuclease P/MRP subunit p14"
                     /db_xref="GeneID:361020"
                     /db_xref="RGD:1305436"
     exon            1..195
                     /gene="Rpp14"
                     /inference="alignment:Splign:2.1.0"
     exon            196..348
                     /gene="Rpp14"
                     /inference="alignment:Splign:2.1.0"
     exon            349..436
                     /gene="Rpp14"
                     /inference="alignment:Splign:2.1.0"
     CDS             366..734
                     /gene="Rpp14"
                     /EC_number="3.1.26.5"
                     /note="ribonuclease P 14 subunit homolog; ribonuclease P
                     14kDa subunit; ribonuclease P/MRP 14 subunit"
                     /codon_start=1
                     /product="ribonuclease P protein subunit p14"
                     /protein_id="NP_001101842.2"
                     /db_xref="GeneID:361020"
                     /db_xref="RGD:1305436"
                     /translation="MPATAYERVVYKSPSEYHYMKVCLEFQEHGVGLNGAQFKQLLVS
                     ALKDLFGEVGAALPVDVLTYDETTLSAILRVCSSGLAKLWSSLTLFGAYKGKKCAFRV
                     SQVSPFLLALSGNSREQVLD"
     exon            437..521
                     /gene="Rpp14"
                     /inference="alignment:Splign:2.1.0"
     exon            522..598
                     /gene="Rpp14"
                     /inference="alignment:Splign:2.1.0"
     exon            599..677
                     /gene="Rpp14"
                     /inference="alignment:Splign:2.1.0"
     exon            678..1870
                     /gene="Rpp14"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtccggcgat gcgtctgtgg ggcggtgcgg aacggactct aatgtaaata caccagtttt
       61 ccaggaccaa acttgggctg ctgcgtggga actccgaccc gtgccgagtt gtagtaagcc
      121 tgcaattgac aggaacgcgg ctatcccagt gagcggcttc gttctgcgcc gggacggctt
      181 aaccgcgcgc ggcagtgccc aggaagaaca agagagagtg ttgaatcctc tggaactgga
      241 gtataaactt atgtcagcca ccctgtgggt actggaaaat caacccagcc agcttctcta
      301 caagaacagc aagtgctctg aacagctgag acatctctcc agccctaagt accccatgtt
      361 ggaagatgcc agctactgct tatgaaaggg tagtttataa gagcccttcg gagtaccact
      421 acatgaaagt ctgcttagag tttcaggaac atggggttgg actgaatgga gcccagttca
      481 aacagctact tgtttcagcg ctgaaagacc tgtttgggga ggttggcgct gctttacctg
      541 tggatgttct cacttatgat gagaccacac tgtcagccat cttgagagta tgcagcagtg
      601 gtctggccaa attgtggagc tctttgaccc tgtttggagc ctataaaggc aagaaatgtg
      661 ccttcagagt gagtcaggtg tctccctttc tcctcgcgtt atctggcaat agcagggaac
      721 aagtattgga ctgagctctt acagttccag atacaaacac tctcgacagt gtccttaggt
      781 gtctacgcag tttggaaaca agcaggctaa agcccctatt gttgacatcc ggagatgctg
      841 aagatgtgga gtgggcttca gaggagactg tggcagcatc gtgtggtacc aacagggcag
      901 tgttttcggt gtgtgcacat gaaagttgga gaccgcgctg aacttagcag agccttcaca
      961 cagcaggacg tggctacctt ctcagagtta acgggagacg ccaatccttt gcatttaagt
     1021 gaagattttg caaagcacac caggtttgga aagacagttg tgcatggagt tttgataaat
     1081 ggacttattt cagctctcct gggcactaaa atgccagggc caggctgtgt gtttctttcc
     1141 caggagatta aattcccagc tcctttgtat attggagaag tggttttagc atcggcagaa
     1201 gtgaaaaggt tgaagcagtc tgttgctgtt gttgaagtgt cctgctgtgt aatagaaagt
     1261 aagaagacag ttatggaagg cttggttaaa attatggtcc caggagctcc tagatcctga
     1321 aatagaaatg taaagttgta cgttcagacc ctgtgctctt gctatcagtg acttctgggc
     1381 agctgggctg ttgctcttca agaagtacac gcagaagcca tgtgtgggag aggagatttc
     1441 cagattagcg cgtggtttgt ccagacttac atgcaagagc tcgtcatcta cgaggtttgg
     1501 atttcttttt tccaattaaa aaacagttga gaggggtcgg ggatttagct cagtggtaga
     1561 gcgcttgcct aggaagcgca aggccctggg ttcggtcccc agctccaaaa aaaagaacca
     1621 aaaaaaaaaa aaacaaaaca gttgagagag gctggagagg tggcttctca gctaagaaca
     1681 ctggctgctc ttccagagga tctgggttca actcctagta cccacatggc ggctcacaac
     1741 tgtctgtaac tccagtctca ggtgatccca caccgtcttc tgacctatgc cgaaactaca
     1801 tgcacatggt acactgacgt acatgcaggc aaaatacaaa tacaataata ataaagtctt
     1861 tttaaattga
//
