LOCUS       NM_013067               2261 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus ribophorin I (Rpn1), mRNA.
ACCESSION   NM_013067
VERSION     NM_013067.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2261)
  AUTHORS   Yamamoto,S., Yamazaki,T., Komazaki,S., Yamashita,T., Osaki,M.,
            Matsubayashi,M., Kidoya,H., Takakura,N., Yamazaki,D. and
            Kakizawa,S.
  TITLE     Contribution of calumin to embryogenesis through participation in
            the endoplasmic reticulum-associated degradation activity
  JOURNAL   Dev Biol 393 (1), 33-43 (2014)
   PUBMED   25009997
REFERENCE   2  (bases 1 to 2261)
  AUTHORS   Zanivan,S., Maione,F., Hein,M.Y., Hernandez-Fernaud,J.R.,
            Ostasiewicz,P., Giraudo,E. and Mann,M.
  TITLE     SILAC-based proteomics of human primary endothelial cell
            morphogenesis unveils tumor angiogenic markers
  JOURNAL   Mol Cell Proteomics 12 (12), 3599-3611 (2013)
   PUBMED   23979707
REFERENCE   3  (bases 1 to 2261)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   4  (bases 1 to 2261)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   5  (bases 1 to 2261)
  AUTHORS   Wilson,C.M. and High,S.
  TITLE     Ribophorin I acts as a substrate-specific facilitator of
            N-glycosylation
  JOURNAL   J Cell Sci 120 (Pt 4), 648-657 (2007)
   PUBMED   17264154
REFERENCE   6  (bases 1 to 2261)
  AUTHORS   Kelleher,D.J., Karaoglu,D., Mandon,E.C. and Gilmore,R.
  TITLE     Oligosaccharyltransferase isoforms that contain different catalytic
            STT3 subunits have distinct enzymatic properties
  JOURNAL   Mol Cell 12 (1), 101-111 (2003)
   PUBMED   12887896
REFERENCE   7  (bases 1 to 2261)
  AUTHORS   Harding,H.P., Zhang,Y. and Ron,D.
  TITLE     Protein translation and folding are coupled by an
            endoplasmic-reticulum-resident kinase
  JOURNAL   Nature 397 (6716), 271-274 (1999)
   PUBMED   9930704
  REMARK    Erratum:[Nature 1999 Mar 4;398(6722):90]
REFERENCE   8  (bases 1 to 2261)
  AUTHORS   Kumar,V., Heinemann,F.S. and Ozols,J.
  TITLE     Interleukin-2 induces N-glycosylation in T-cells: characterization
            of human lymphocyte oligosaccharyltransferase
  JOURNAL   Biochem Biophys Res Commun 247 (2), 524-529 (1998)
   PUBMED   9642163
REFERENCE   9  (bases 1 to 2261)
  AUTHORS   Behal,A., Prakash,K., D'Eustachio,P., Adesnik,M., Sabatini,D.D. and
            Kreibich,G.
  TITLE     Structure and chromosomal location of the rat ribophorin I gene
  JOURNAL   J Biol Chem 265 (14), 8252-8258 (1990)
   PUBMED   2335524
REFERENCE   10 (bases 1 to 2261)
  AUTHORS   Harnik-Ort,V., Prakash,K., Marcantonio,E., Colman,D.R.,
            Rosenfeld,M.G., Adesnik,M., Sabatini,D.D. and Kreibich,G.
  TITLE     Isolation and characterization of cDNA clones for rat ribophorin I:
            complete coding sequence and in vitro synthesis and insertion of
            the encoded product into endoplasmic reticulum membranes
  JOURNAL   J Cell Biol 104 (4), 855-863 (1987)
   PUBMED   3031084
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Feb 5, 2015 this sequence version replaced NM_013067.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC061756.1, X05300.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-302               JAXUCZ010000004.1  122100976-122101277
            303-367             JAXUCZ010000004.1  122104875-122104939
            368-674             JAXUCZ010000004.1  122106334-122106640
            675-884             JAXUCZ010000004.1  122111278-122111487
            885-1077            JAXUCZ010000004.1  122113475-122113667
            1078-1177           JAXUCZ010000004.1  122117578-122117677
            1178-1316           JAXUCZ010000004.1  122118925-122119063
            1317-1436           JAXUCZ010000004.1  122119162-122119281
            1437-1682           JAXUCZ010000004.1  122120308-122120553
            1683-2261           JAXUCZ010000004.1  122121804-122122382
FEATURES             Location/Qualifiers
     source          1..2261
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q34"
     gene            1..2261
                     /gene="Rpn1"
                     /gene_synonym="RIBI; RPN-I"
                     /note="ribophorin I"
                     /db_xref="GeneID:25596"
                     /db_xref="RGD:3594"
     exon            1..302
                     /gene="Rpn1"
                     /gene_synonym="RIBI; RPN-I"
                     /inference="alignment:Splign:2.1.0"
     CDS             45..1865
                     /gene="Rpn1"
                     /gene_synonym="RIBI; RPN-I"
                     /EC_number="2.4.99.18"
                     /note="dolichyl-diphosphooligosaccharide--protein
                     glycosyltransferase subunit 1; ribophorin1; ribophorin-1;
                     dolichyl-diphosphooligosaccharide--protein
                     glycosyltransferase 67 kDa subunit;
                     dolichyl-diphosphooligosaccharide--protein
                     glycosyltransferase subunit 1-like"
                     /codon_start=1
                     /product="dolichyl-diphosphooligosaccharide--protein
                     glycosyltransferase subunit 1 precursor"
                     /protein_id="NP_037199.2"
                     /db_xref="GeneID:25596"
                     /db_xref="RGD:3594"
                     /translation="MEAPIVLLLLLWLGALAPTPGSASSEAPPLVNEDVKRTVDLSSH
                     LAKVTAEVVLAHPGGGSTARASSFVLALEPELESRLAHLGVQVKGEDEEDNNLEVRET
                     KMKGKSGRFFTVKLPVALDPGSKISIVVETVYTHVLHPYPTQITQSEKQFVVFEGNHY
                     FYSPYPTKTQTMRVRLASRNVESHTKLGNPSRSEDILDYGPFKDIPAYSQDTFKVHYE
                     NNSPFLTITSMTRVIEVSHWGNIAVEENVDLKHTGAVLKGPFSRYDYQRQPDSGISSI
                     RSFKTILPAAAQDVYYRDEIGNVSTSHLLILDDSVEMEIRPRFPLFGGWKTHYIVGYN
                     LPSYEYLYNLGDQYALKMRFVDHVFDEQVIDSLTVKIILPEGAKNIQVDSPYDISRAP
                     DELHYTYLDTFGRPVIVAYKKNLVEQHIQDIVVHYTFNKVLMLQEPLLVVAAFYILFF
                     TVIIYVRLDFSITKDPAAEARMKVACITEQVLTLVNKRLGLYRHFDETVNRYKQSRDI
                     STLNSGKKSLETEHKAVTSEIAVLQSRLKTEGSDLCDRVSEMQKLDAQVKELVLKSAV
                     EAERLVAGKLKKDTYIENEKLSSGKRQELVTKIDHILDAL"
     exon            303..367
                     /gene="Rpn1"
                     /gene_synonym="RIBI; RPN-I"
                     /inference="alignment:Splign:2.1.0"
     exon            368..674
                     /gene="Rpn1"
                     /gene_synonym="RIBI; RPN-I"
                     /inference="alignment:Splign:2.1.0"
     exon            675..884
                     /gene="Rpn1"
                     /gene_synonym="RIBI; RPN-I"
                     /inference="alignment:Splign:2.1.0"
     exon            885..1077
                     /gene="Rpn1"
                     /gene_synonym="RIBI; RPN-I"
                     /inference="alignment:Splign:2.1.0"
     exon            1078..1177
                     /gene="Rpn1"
                     /gene_synonym="RIBI; RPN-I"
                     /inference="alignment:Splign:2.1.0"
     exon            1178..1316
                     /gene="Rpn1"
                     /gene_synonym="RIBI; RPN-I"
                     /inference="alignment:Splign:2.1.0"
     exon            1317..1436
                     /gene="Rpn1"
                     /gene_synonym="RIBI; RPN-I"
                     /inference="alignment:Splign:2.1.0"
     exon            1437..1682
                     /gene="Rpn1"
                     /gene_synonym="RIBI; RPN-I"
                     /inference="alignment:Splign:2.1.0"
     exon            1683..2261
                     /gene="Rpn1"
                     /gene_synonym="RIBI; RPN-I"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggggggggg cggggcgcgt gtcggtggcg ctcagctcgc ggtcatggag gcgccgatcg
       61 tcttgctgct gctgctatgg ctcggggcct tggccccgac gcccggcagc gcctcttcgg
      121 aggctccgcc gctggtcaac gaggacgtga agcgcacggt ggacctgagc agccacctag
      181 ccaaggtgac ggctgaggtg gtcctggcgc acccgggcgg cggctctaca gcacgagcca
      241 gctctttcgt tctggccctg gagcccgaac tggagtcgcg acttgcacac ctaggcgtgc
      301 aggtaaaggg agaagatgag gaagacaaca acctagaagt acgagaaacc aaaatgaagg
      361 ggaaaagtgg gaggtttttc accgtcaagc tcccagttgc tcttgatcct gggtccaaga
      421 tctcaatcgt tgtggaaact gtctacaccc atgtgcttca tccatacccg actcagataa
      481 ctcagtcaga gaaacagttt gtggtgtttg agggcaacca ttacttctac tctccctatc
      541 caacaaagac ccagaccatg cgagtgagac ttgcttcccg aaatgtggag agccatacca
      601 agctggggaa cccctcaagg tctgaggaca tcctggacta tgggcctttt aaagacatcc
      661 ctgcctacag tcaggatact ttcaaagtac attatgagaa caatagccct ttcctgacca
      721 tcaccagtat gacccgggtc attgaggttt ctcactgggg caatattgct gtggaagaga
      781 acgtggactt gaagcataca ggtgcggtgc tgaagggacc tttctcccgc tacgattacc
      841 agaggcagcc tgacagtggg atctcctcca ttcgttcttt taagaccatc cttcctgctg
      901 ctgcccagga tgtgtattac cgggatgaaa tcggtaatgt ttccaccagc cacctcctta
      961 ttttggatga ctccgtggaa atggaaatcc ggcctcgatt tcctctcttt ggagggtgga
     1021 agacacacta catcgttggt tacaacctcc caagctatga gtacctctat aatctgggtg
     1081 accagtatgc actgaagatg cggtttgtag accacgtgtt tgatgagcaa gtgatagatt
     1141 ctctgacagt gaagatcatc cttcctgagg gagccaagaa catccaggta gacagtccct
     1201 acgatattag ccgggcccca gatgagctgc attacaccta cctagacaca ttcggccgcc
     1261 cggtgattgt tgcttacaag aagaatctag ttgaacagca cattcaggac attgtggtgc
     1321 actacacatt caacaaggtg ctcatgctgc aggagcctct gctggttgtg gccgccttct
     1381 acatcctgtt cttcaccgtc atcatctacg tccgtctaga cttttccatc accaaggacc
     1441 cagcagcaga agccaggatg aaagtggcct gtatcacaga gcaggtctta accctggtca
     1501 acaagaggtt aggcctctac cgtcactttg atgagactgt caatagatac aagcagtccc
     1561 gggacatctc taccctcaat agtggcaaga agagcctaga gacagagcac aaagctgtga
     1621 ccagtgagat tgctgtgctg cagtctaggc tgaagacgga gggctctgac ctgtgtgaca
     1681 gggtgagcga aatgcagaag ctggacgcgc aggtcaagga gctggtactg aagtctgcgg
     1741 tggaggcaga gaggctggtg gctggcaagc tcaagaagga cacatacatc gagaatgaaa
     1801 agctcagctc aggaaaacgc caggagctgg tcaccaagat cgaccacatc ctggacgctc
     1861 tgtagctctt gtctccagag caggcctggg ttgcctacac ttctggatgg aataggtaga
     1921 gggaggaagt tgtgattagc ctaagacctc aagaaaaaag ctgaggccca tccatggctg
     1981 tgtaagaagc ttgtccctta tttctgaatg gttctctttt ttacaaaaac aaaaacctaa
     2041 acaaaaatcc tgtttaaaaa acaaacttgg ttgtgttttg agcaaaagca ttttcagtag
     2101 ttgattgctg ttttgttttg atacctgggt attttttctg tctgtaagcc ctgttttatg
     2161 gccttctgat tcctaatgtt tggttctttt gtgagcgtat gcatggtttt ttaaaagtgt
     2221 gtatgaccaa ataaaaataa aggagggact gtgaacattg g
//
