LOCUS       NM_001034916             845 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus ribosomal protein L8 (Rpl8), mRNA.
ACCESSION   NM_001034916 XM_343278
VERSION     NM_001034916.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 845)
  AUTHORS   Behrmann,E., Loerke,J., Budkevich,T.V., Yamamoto,K., Schmidt,A.,
            Penczek,P.A., Vos,M.R., Burger,J., Mielke,T., Scheerer,P. and
            Spahn,C.M.
  TITLE     Structural snapshots of actively translating human ribosomes
  JOURNAL   Cell 161 (4), 845-857 (2015)
   PUBMED   25957688
REFERENCE   2  (bases 1 to 845)
  AUTHORS   Anger,A.M., Armache,J.P., Berninghausen,O., Habeck,M., Subklewe,M.,
            Wilson,D.N. and Beckmann,R.
  TITLE     Structures of the human and Drosophila 80S ribosome
  JOURNAL   Nature 497 (7447), 80-85 (2013)
   PUBMED   23636399
REFERENCE   3  (bases 1 to 845)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (bases 1 to 845)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (bases 1 to 845)
  AUTHORS   Bayes,A., Collins,M.O., Croning,M.D., van de Lagemaat,L.N.,
            Choudhary,J.S. and Grant,S.G.
  TITLE     Comparative study of human and mouse postsynaptic proteomes finds
            high compositional conservation and abundance differences for key
            synaptic proteins
  JOURNAL   PLoS One 7 (10), e46683 (2012)
   PUBMED   23071613
REFERENCE   6  (bases 1 to 845)
  AUTHORS   Angelastro,J.M., Torocsik,B. and Greene,L.A.
  TITLE     Nerve growth factor selectively regulates expression of transcripts
            encoding ribosomal proteins
  JOURNAL   BMC Neurosci 3, 3 (2002)
   PUBMED   11922865
REFERENCE   7  (bases 1 to 845)
  AUTHORS   Hanes,J., Klaudiny,J., von der Kammer,H. and Scheit,K.H.
  TITLE     Characterization by cDNA cloning of the mRNA of human ribosomal
            protein L8
  JOURNAL   Biochem Biophys Res Commun 197 (3), 1223-1228 (1993)
   PUBMED   7506540
REFERENCE   8  (bases 1 to 845)
  AUTHORS   Chan,Y.L. and Wool,I.G.
  TITLE     The primary structure of rat ribosomal protein L8
  JOURNAL   Biochem Biophys Res Commun 185 (2), 539-547 (1992)
   PUBMED   1610349
REFERENCE   9  (bases 1 to 845)
  AUTHORS   Ulbrich,N., Lin,A. and Wool,I.G.
  TITLE     Identification by affinity chromatography of the eukaryotic
            ribosomal proteins that bind to 5.8 S ribosomal ribonucleic acid
  JOURNAL   J Biol Chem 254 (17), 8641-8645 (1979)
   PUBMED   468846
REFERENCE   10 (bases 1 to 845)
  AUTHORS   Tsurugi,K., Collatz,E., Todokoro,K. and Wool,I.G.
  TITLE     Isolation of eukaryotic ribosomal proteins. Purification and
            characterization of 60 S ribosomal subunit proteins L3, L6, L7',
            L8, L10, L15, L17, L18, L19, L23', L25, L27', L28, L29, L31, L32,
            L34, L35, L36, L36', and L37'
  JOURNAL   J Biol Chem 252 (11), 3961-3969 (1977)
   PUBMED   863909
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Nov 20, 2020 this sequence version replaced NM_001034916.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ225104.1, CF111102.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-25                JAXUCZ010000007.1  110506815-110506839
            26-173              JAXUCZ010000007.1  110507028-110507175
            174-315             JAXUCZ010000007.1  110507265-110507406
            316-534             JAXUCZ010000007.1  110507534-110507752
            535-650             JAXUCZ010000007.1  110508647-110508762
            651-845             JAXUCZ010000007.1  110508912-110509106
FEATURES             Location/Qualifiers
     source          1..845
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..845
                     /gene="Rpl8"
                     /note="ribosomal protein L8"
                     /db_xref="GeneID:26962"
                     /db_xref="RGD:619827"
     exon            1..25
                     /gene="Rpl8"
                     /inference="alignment:Splign:2.1.0"
     exon            26..173
                     /gene="Rpl8"
                     /inference="alignment:Splign:2.1.0"
     CDS             36..809
                     /gene="Rpl8"
                     /note="60S ribosomal protein L8"
                     /codon_start=1
                     /product="large ribosomal subunit protein uL2"
                     /protein_id="NP_001030088.2"
                     /db_xref="GeneID:26962"
                     /db_xref="RGD:619827"
                     /translation="MGRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGI
                     VKDIIHDPGRGAPLAKVVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVL
                     PVGTMPEGTIVCCLEEKPGDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISS
                     ANRAVVGVVAGGGRIDKPILKAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQH
                     IGKPSTIRRDAPAGRKVGLIAARRTGRLRGTKTVQEKEN"
     exon            174..315
                     /gene="Rpl8"
                     /inference="alignment:Splign:2.1.0"
     exon            316..534
                     /gene="Rpl8"
                     /inference="alignment:Splign:2.1.0"
     exon            535..650
                     /gene="Rpl8"
                     /inference="alignment:Splign:2.1.0"
     exon            651..845
                     /gene="Rpl8"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctcttttggc cttgcttgcc ggcagactcg ccgccatggg ccgtgtgatc cgaggccaga
       61 ggaaaggtgc cggttctgtg tttcgtgcgc acgtgaagca ccgtaaggga gccgcgcgtc
      121 tgcgtgctgt ggacttcgcg gagcgacacg gctacattaa aggcatcgta aaggacatca
      181 ttcatgaccc tggccgcggc gctcccctcg cgaaagtagt ctttcgtgat ccctatcgat
      241 tcaagaagcg gacagagctg ttcatcgccg cagagggaat ccacactgga cagtttgtgt
      301 actgcggcaa gaaggcccag ctgaatattg gcaatgtttt gcccgtgggc accatgcctg
      361 agggtactat cgtgtgttgt ctggaggaga agcctgggga caggggcaag ctggcacgag
      421 cctccgggaa ctatgctaca gtcatctccc acaacccaga gaccaagaag acccgagtga
      481 agctgccttc agggtccaag aaggtcattt cctctgctaa ccgagctgtt gttggtgtcg
      541 tggctggcgg gggcagaatt gacaagccta tcttaaaggc tggccgtgcc taccataagt
      601 acaaggcaaa gaggaactgc tggccacgtg tgcggggtgt tgccatgaat cctgtggagc
      661 atccctttgg cggtggtaac caccagcaca ttggcaagcc ttccactatc cgaagagatg
      721 ccccagctgg gcgcaaagtg ggtctcattg ctgcccgccg gactggacgg ctacgtggaa
      781 ccaaaactgt acaggagaag gagaactaga gttcaggagc taataaagta tgtgctttgg
      841 ctaat
//
