LOCUS       NM_198753               1298 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus ribosomal protein L3 (Rpl3), mRNA.
ACCESSION   NM_198753 XM_216988
VERSION     NM_198753.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1298)
  AUTHORS   Anger,A.M., Armache,J.P., Berninghausen,O., Habeck,M., Subklewe,M.,
            Wilson,D.N. and Beckmann,R.
  TITLE     Structures of the human and Drosophila 80S ribosome
  JOURNAL   Nature 497 (7447), 80-85 (2013)
   PUBMED   23636399
REFERENCE   2  (bases 1 to 1298)
  AUTHORS   Cloutier,P., Lavallee-Adam,M., Faubert,D., Blanchette,M. and
            Coulombe,B.
  TITLE     A newly uncovered group of distantly related lysine
            methyltransferases preferentially interact with molecular
            chaperones to regulate their activity
  JOURNAL   PLoS Genet 9 (1), e1003210 (2013)
   PUBMED   23349634
REFERENCE   3  (bases 1 to 1298)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (bases 1 to 1298)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (bases 1 to 1298)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   6  (bases 1 to 1298)
  AUTHORS   Kuwano,Y. and Wool,I.G.
  TITLE     The primary structure of rat ribosomal protein L3
  JOURNAL   Biochem Biophys Res Commun 187 (1), 58-64 (1992)
   PUBMED   1520347
REFERENCE   7  (bases 1 to 1298)
  AUTHORS   Kargel,H.J., Stahl,J., Gross,B., Knespel,S., Bielka,H. and
            Saarma,M.
  TITLE     Studies on interaction of 5 S RNA with ribosomal proteins
  JOURNAL   FEBS Lett 220 (1), 126-128 (1987)
   PUBMED   3301408
REFERENCE   8  (bases 1 to 1298)
  AUTHORS   Hultin,T.
  TITLE     Selective high-efficiency cross-linking of mammalian ribosomal
            proteins with cleavable thiol-directed heterobifunctional reagents:
            identification and binding directions of major protein complexes
  JOURNAL   Biochim Biophys Acta 872 (3), 226-235 (1986)
   PUBMED   3730400
REFERENCE   9  (bases 1 to 1298)
  AUTHORS   Otaka,E., Higo,K. and Itoh,T.
  TITLE     Yeast ribosomal proteins: VII. Cytoplasmic ribosomal proteins from
            Schizosaccharomyces pombe
  JOURNAL   Mol Gen Genet 191 (3), 519-524 (1983)
   PUBMED   6355773
REFERENCE   10 (bases 1 to 1298)
  AUTHORS   Uchiumi,T., Terao,K. and Ogata,K.
  TITLE     Identification of neighboring protein pairs in rat liver 60S
            ribosomal subunits cross-linked with dimethyl suberimidate or
            dimethyl 3,3'-dithiobispropionimidate
  JOURNAL   J Biochem 88 (4), 1033-1044 (1980)
   PUBMED   7451403
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Mar 18, 2021 this sequence version replaced NM_198753.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ212900.1, FQ222720.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840115, SAMN12840117
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-30                JAXUCZ010000007.1  113507961-113507990 c
            31-223              JAXUCZ010000007.1  113507022-113507214 c
            224-392             JAXUCZ010000007.1  113506180-113506348 c
            393-528             JAXUCZ010000007.1  113505302-113505437 c
            529-715             JAXUCZ010000007.1  113504829-113505015 c
            716-876             JAXUCZ010000007.1  113504185-113504345 c
            877-978             JAXUCZ010000007.1  113503432-113503533 c
            979-1074            JAXUCZ010000007.1  113503064-113503159 c
            1075-1194           JAXUCZ010000007.1  113502833-113502952 c
            1195-1298           JAXUCZ010000007.1  113502605-113502708 c
FEATURES             Location/Qualifiers
     source          1..1298
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..1298
                     /gene="Rpl3"
                     /note="ribosomal protein L3"
                     /db_xref="GeneID:300079"
                     /db_xref="RGD:735105"
     exon            1..30
                     /gene="Rpl3"
                     /inference="alignment:Splign:2.1.0"
     CDS             28..1239
                     /gene="Rpl3"
                     /EC_number="3.6.5.3"
                     /note="60S ribosomal protein L3; L4"
                     /codon_start=1
                     /product="large ribosomal subunit protein uL3"
                     /protein_id="NP_942048.1"
                     /db_xref="GeneID:300079"
                     /db_xref="RGD:735105"
                     /translation="MSHRKFSAPRHGSLGFLPRKRSSRHRGKVKSFPKDDPSKPVHLT
                     AFLGYKAGMTHIVREVDRPGSKVNKKEVVEAVTIVETPPMVVVGIVGYVETPRGLRTF
                     KTVFAEHISDECKRRFYKNWHKSKKKAFTKYCKKWQDDTGKKQLEKDFNSMKKYCQVI
                     RIIAHTQMRLLPLRQKKAHLMEIQVNGGTVAEKLDWARERLEQQVPVNQVFGQDEMID
                     VIGVTKGKGYKGVTSRWHTKKLPRKTHRGLRKVACIGAWHPARVAFSVARAGQKGYHH
                     RTEINKKIYKIGQGYLIKDGKLIKNNASTDYDLSDKSINPLGGFVHYGEVTNDFIMLK
                     GCVVGTKKRVLTLRKSLLVQTKRRALEKIDLKFIDTTSKFGHGRFQTMEEKKAFMGPL
                     KKDRIAKEEGA"
     exon            31..223
                     /gene="Rpl3"
                     /inference="alignment:Splign:2.1.0"
     exon            224..392
                     /gene="Rpl3"
                     /inference="alignment:Splign:2.1.0"
     exon            393..528
                     /gene="Rpl3"
                     /inference="alignment:Splign:2.1.0"
     exon            529..715
                     /gene="Rpl3"
                     /inference="alignment:Splign:2.1.0"
     exon            716..876
                     /gene="Rpl3"
                     /inference="alignment:Splign:2.1.0"
     exon            877..978
                     /gene="Rpl3"
                     /inference="alignment:Splign:2.1.0"
     exon            979..1074
                     /gene="Rpl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1075..1194
                     /gene="Rpl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1195..1298
                     /gene="Rpl3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tctctatcgg cggcgtgtgg cggcgagatg tctcacagga aattctcagc tcctaggcat
       61 gggtccttgg gcttcttgcc tcggaagcgc agcagccggc atcgtggaaa agtgaagagc
      121 ttccctaagg atgacccttc caagcctgtt cacctcacag ccttcctagg gtacaaggct
      181 ggcatgaccc acattgtccg ggaagttgac cggccaggat ctaaggtgaa taagaaagaa
      241 gttgtggagg ctgtgaccat tgtggaaacc ccacccatgg tggttgtggg tattgtggga
      301 tatgtagaaa ccccacgagg cctccggacc ttcaagactg tatttgctga gcacatcagc
      361 gatgagtgta aaaggcgttt ctataagaat tggcacaaat ctaagaagaa ggcttttacc
      421 aagtactgta agaaatggca agatgacaca ggcaagaagc agctggagaa ggacttcaac
      481 agcatgaaga agtactgcca ggtcatccgc ataattgctc acactcagat gcgcctgctt
      541 cctctgcgcc agaagaaggc acacttgatg gagatccagg tgaatggggg cactgtagct
      601 gagaagctag actgggcccg agagaggctg gagcagcagg tccctgtgaa ccaggtgttt
      661 gggcaagatg agatgattga cgtcattggc gtgacaaagg gcaaaggcta caaaggggtg
      721 accagtcgtt ggcatacaaa gaagctgccc cgaaagaccc acagaggtct gcgcaaagtt
      781 gcttgtattg gagcttggca tcctgcccgt gtagccttct ctgtggctcg agctgggcag
      841 aaaggctacc atcaccgaac agagatcaac aagaagattt acaagattgg tcaaggctac
      901 ctcatcaagg atggtaagct gatcaagaac aatgcatcta ctgactacga cctgtctgac
      961 aagagcatca acccactggg tggctttgtc cattatggtg aggtgaccaa tgacttcatc
     1021 atgctcaaag gctgtgtggt gggaaccaag aagcgagtgc ttactctccg gaagtccttg
     1081 ctggtccaga ccaagcgtcg ggctcttgag aagattgacc tgaagttcat tgacaccacc
     1141 tccaaattcg gacatggtcg cttccagacc atggaggaaa agaaagcatt catgggaccg
     1201 ctcaagaaag atcgcattgc caaggaggaa ggtgcctgat gccaggagta ctttgtgcag
     1261 ctggtggggt ctcatcaata aaatattttc aattaaca
//
