LOCUS       NM_022514                463 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ribosomal protein L27 (Rpl27), mRNA.
ACCESSION   NM_022514
VERSION     NM_022514.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Wang,R., Yoshida,K., Toki,T., Sawada,T., Uechi,T., Okuno,Y.,
            Sato-Otsubo,A., Kudo,K., Kamimaki,I., Kanezaki,R., Shiraishi,Y.,
            Chiba,K., Tanaka,H., Terui,K., Sato,T., Iribe,Y., Ohga,S.,
            Kuramitsu,M., Hamaguchi,I., Ohara,A., Hara,J., Goi,K.,
            Matsubara,K., Koike,K., Ishiguro,A., Okamoto,Y., Watanabe,K.,
            Kanno,H., Kojima,S., Miyano,S., Kenmochi,N., Ogawa,S. and Ito,E.
  TITLE     Loss of function mutations in RPL27 and RPS27 identified by
            whole-exome sequencing in Diamond-Blackfan anaemia
  JOURNAL   Br J Haematol 168 (6), 854-864 (2015)
   PUBMED   25424902
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Voorhees,R.M., Fernandez,I.S., Scheres,S.H. and Hegde,R.S.
  TITLE     Structure of the mammalian ribosome-Sec61 complex to 3.4 A
            resolution
  JOURNAL   Cell 157 (7), 1632-1643 (2014)
   PUBMED   24930395
REFERENCE   3  (bases 1 to 463)
  AUTHORS   Zanivan,S., Maione,F., Hein,M.Y., Hernandez-Fernaud,J.R.,
            Ostasiewicz,P., Giraudo,E. and Mann,M.
  TITLE     SILAC-based proteomics of human primary endothelial cell
            morphogenesis unveils tumor angiogenic markers
  JOURNAL   Mol Cell Proteomics 12 (12), 3599-3611 (2013)
   PUBMED   23979707
REFERENCE   4  (bases 1 to 463)
  AUTHORS   Cheema,M.U., Poulsen,E.T., Enghild,J.J., Hoorn,E.J., Fenton,R.A.
            and Praetorius,J.
  TITLE     Aldosterone and angiotensin II induce protein aggregation in renal
            proximal tubules
  JOURNAL   Physiol Rep 1 (4), e00064 (2013)
   PUBMED   24303148
  REMARK    Erratum:[Physiol Rep. 2014 Feb 1;2(2):e00251. Hoorn, Ewout
            [corrected to Hoorn, Ewout J]]
REFERENCE   5  (bases 1 to 463)
  AUTHORS   Anger,A.M., Armache,J.P., Berninghausen,O., Habeck,M., Subklewe,M.,
            Wilson,D.N. and Beckmann,R.
  TITLE     Structures of the human and Drosophila 80S ribosome
  JOURNAL   Nature 497 (7447), 80-85 (2013)
   PUBMED   23636399
REFERENCE   6  (bases 1 to 463)
  AUTHORS   Maggi,L.B. Jr., Kuchenruether,M., Dadey,D.Y., Schwope,R.M.,
            Grisendi,S., Townsend,R.R., Pandolfi,P.P. and Weber,J.D.
  TITLE     Nucleophosmin serves as a rate-limiting nuclear export chaperone
            for the Mammalian ribosome
  JOURNAL   Mol Cell Biol 28 (23), 7050-7065 (2008)
   PUBMED   18809582
REFERENCE   7  (bases 1 to 463)
  AUTHORS   Odintsova,T.I., Muller,E.C., Ivanov,A.V., Egorov,T.A., Bienert,R.,
            Vladimirov,S.N., Kostka,S., Otto,A., Wittmann-Liebold,B. and
            Karpova,G.G.
  TITLE     Characterization and analysis of posttranslational modifications of
            the human large cytoplasmic ribosomal subunit proteins by mass
            spectrometry and Edman sequencing
  JOURNAL   J Protein Chem 22 (3), 249-258 (2003)
   PUBMED   12962325
REFERENCE   8  (bases 1 to 463)
  AUTHORS   Tanaka,T., Kuwano,Y., Ishikawa,K. and Ogata,K.
  TITLE     Nucleotide sequence of cloned cDNA specific for rat ribosomal
            protein L27
  JOURNAL   Eur J Biochem 173 (1), 53-56 (1988)
   PUBMED   2833393
REFERENCE   9  (bases 1 to 463)
  AUTHORS   Hultin,T.
  TITLE     Selective high-efficiency cross-linking of mammalian ribosomal
            proteins with cleavable thiol-directed heterobifunctional reagents:
            identification and binding directions of major protein complexes
  JOURNAL   Biochim Biophys Acta 872 (3), 226-235 (1986)
   PUBMED   3730400
REFERENCE   10 (bases 1 to 463)
  AUTHORS   Tsurugi,K., Collatz,E., Wool,E.G. and Lin,A.
  TITLE     Isolation of eukaryotic ribosomal proteins. Purification and
            characterization of the 60 S ribosomal subunit proteins L4, L5, L7,
            L9, L11, L12, L13, L21, L22, L23, L26, L27, L30, L33, L35', L37,
            and L39
  JOURNAL   J Biol Chem 251 (24), 7940-7946 (1976)
   PUBMED   1002715
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from X07424.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X07424.1, FM103704.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="W"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q31"
     gene            1..463
                     /gene="Rpl27"
                     /note="ribosomal protein L27"
                     /db_xref="GeneID:64306"
                     /db_xref="RGD:621192"
     exon            1..13
                     /gene="Rpl27"
                     /inference="alignment:Splign:2.1.0"
     exon            14..96
                     /gene="Rpl27"
                     /inference="alignment:Splign:2.1.0"
     CDS             16..426
                     /gene="Rpl27"
                     /EC_number="3.6.5.3"
                     /note="60S ribosomal protein L27"
                     /codon_start=1
                     /product="large ribosomal subunit protein eL27"
                     /protein_id="NP_071959.1"
                     /db_xref="GeneID:64306"
                     /db_xref="RGD:621192"
                     /translation="MGKFMKPGKVVLVLAGRYSGRKAVIVKNIDDGTSDRPYSHALVA
                     GIDRYPRKVTAAMGKKKIAKRSKIKSFVKVYNYNHLMPTRYSVDIPLDKTVVNKDVFR
                     DPALKRKARREAKVKFEERYKTGKNKWFFQKLRF"
     exon            97..266
                     /gene="Rpl27"
                     /inference="alignment:Splign:2.1.0"
     exon            267..377
                     /gene="Rpl27"
                     /inference="alignment:Splign:2.1.0"
     exon            378..463
                     /gene="Rpl27"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgctcgctg tcgaaatggg caagtttatg aaacccggga aagtggtgct ggtcctggct
       61 ggacgctact ccggacgcaa agccgtcatc gtaaagaaca ttgatgatgg cacctccgac
      121 cgcccttaca gccatgccct ggtggctgga attgaccgct atcccagaaa agtgacagct
      181 gccatgggca agaagaagat cgccaagcga tccaagatca agtcctttgt gaaagtttat
      241 aactacaacc acctcatgcc cacaaggtac tctgtggata tccccttgga caaaactgtt
      301 gtcaacaagg atgtgttcag agacccagca ctgaaacgca aggccaggcg ggaggccaag
      361 gtcaagtttg aggagcgata caagacaggg aagaacaaat ggtttttcca gaagcttcgc
      421 ttttagatgt atttttgttt tcgtcattaa aaaaataaaa aat
//
