LOCUS       NM_173340                690 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ribosomal protein L13A (Rpl13a), mRNA.
ACCESSION   NM_173340
VERSION     NM_173340.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 690)
  AUTHORS   Kalendar,R., Belyayev,A., Zachepilo,T., Vaido,A., Maidanyuk,D.,
            Schulman,A.H. and Dyuzhikova,N.
  TITLE     Copy-number variation of housekeeping gene rpl13a in rat strains
            selected for nervous system excitability
  JOURNAL   Mol Cell Probes 33, 11-15 (2017)
   PUBMED   28192165
  REMARK    GeneRIF: We evaluated copy number variation (CNV) for four genes in
            rat strains differing in nervous system excitability. rpl13a copy
            number is significantly reduced in hippocampus and bone marrow in
            rats with a high excitability threshold and stress
REFERENCE   2  (bases 1 to 690)
  AUTHORS   Anger,A.M., Armache,J.P., Berninghausen,O., Habeck,M., Subklewe,M.,
            Wilson,D.N. and Beckmann,R.
  TITLE     Structures of the human and Drosophila 80S ribosome
  JOURNAL   Nature 497 (7447), 80-85 (2013)
   PUBMED   23636399
REFERENCE   3  (bases 1 to 690)
  AUTHORS   Poddar,D., Basu,A., Baldwin,W.M. 3rd, Kondratov,R.V., Barik,S. and
            Mazumder,B.
  TITLE     An extraribosomal function of ribosomal protein L13a in macrophages
            resolves inflammation
  JOURNAL   J Immunol 190 (7), 3600-3612 (2013)
   PUBMED   23460747
REFERENCE   4  (bases 1 to 690)
  AUTHORS   Arif,A., Chatterjee,P., Moodt,R.A. and Fox,P.L.
  TITLE     Heterotrimeric GAIT complex drives transcript-selective translation
            inhibition in murine macrophages
  JOURNAL   Mol Cell Biol 32 (24), 5046-5055 (2012)
   PUBMED   23071094
REFERENCE   5  (bases 1 to 690)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   6  (bases 1 to 690)
  AUTHORS   Mazumder,B., Sampath,P., Seshadri,V., Maitra,R.K., DiCorleto,P.E.
            and Fox,P.L.
  TITLE     Regulated release of L13a from the 60S ribosomal subunit as a
            mechanism of transcript-specific translational control
  JOURNAL   Cell 115 (2), 187-198 (2003)
   PUBMED   14567916
REFERENCE   7  (bases 1 to 690)
  AUTHORS   Odintsova,T.I., Muller,E.C., Ivanov,A.V., Egorov,T.A., Bienert,R.,
            Vladimirov,S.N., Kostka,S., Otto,A., Wittmann-Liebold,B. and
            Karpova,G.G.
  TITLE     Characterization and analysis of posttranslational modifications of
            the human large cytoplasmic ribosomal subunit proteins by mass
            spectrometry and Edman sequencing
  JOURNAL   J Protein Chem 22 (3), 249-258 (2003)
   PUBMED   12962325
REFERENCE   8  (bases 1 to 690)
  AUTHORS   Shahmolky,N., Lefebvre,D.L., Poon,R., Bai,Y., Sharma,M. and
            Rosen,C.F.
  TITLE     UVB and gamma-radiation induce the expression of mRNAs encoding the
            ribosomal subunit L13A in rat keratinocytes
  JOURNAL   Photochem Photobiol 70 (3), 341-347 (1999)
   PUBMED   10483362
REFERENCE   9  (bases 1 to 690)
  AUTHORS   Chan,Y.L., Olvera,J., Gluck,A. and Wool,I.G.
  TITLE     A leucine zipper-like motif and a basic region-leucine zipper-like
            element in rat ribosomal protein L13a. Identification of the tum-
            transplantation antigen P198
  JOURNAL   J Biol Chem 269 (8), 5589-5594 (1994)
   PUBMED   8119894
REFERENCE   10 (bases 1 to 690)
  AUTHORS   Hultin,T.
  TITLE     Selective high-efficiency cross-linking of mammalian ribosomal
            proteins with cleavable thiol-directed heterobifunctional reagents:
            identification and binding directions of major protein complexes
  JOURNAL   Biochim Biophys Acta 872 (3), 226-235 (1986)
   PUBMED   3730400
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC086382.1.
            
            On Oct 8, 2005 this sequence version replaced NM_173340.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC086382.1, EU000472.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760393
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..690
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..690
                     /gene="Rpl13a"
                     /note="ribosomal protein L13A"
                     /db_xref="GeneID:317646"
                     /db_xref="RGD:628697"
     exon            1..29
                     /gene="Rpl13a"
                     /inference="alignment:Splign:2.1.0"
     CDS             15..626
                     /gene="Rpl13a"
                     /note="60S ribosomal protein L13a; neuroprotective protein
                     11"
                     /codon_start=1
                     /product="large ribosomal subunit protein uL13"
                     /protein_id="NP_775462.2"
                     /db_xref="GeneID:317646"
                     /db_xref="RGD:628697"
                     /translation="MAEGQVLVLDGRGHLLGRLAAIVAKQVLLGRKVVVVRCEGINIS
                     GNFYRNKLKYLAFLRKRMNTNPSRGPYHFRAPSRIFWRTVRGMLPHKTKRGQAALERL
                     KVLDGIPPPYDKKKRMVVPAALKVVRLKPTRKFAYLGRLAHEVGWKYQAVTATLEEKR
                     KEKAKIHYRKKKQLLRLRKQAEKNVEKKICKFTEVLKTNGLLV"
     exon            30..102
                     /gene="Rpl13a"
                     /inference="alignment:Splign:2.1.0"
     exon            103..168
                     /gene="Rpl13a"
                     /inference="alignment:Splign:2.1.0"
     exon            169..270
                     /gene="Rpl13a"
                     /inference="alignment:Splign:2.1.0"
     exon            271..356
                     /gene="Rpl13a"
                     /inference="alignment:Splign:2.1.0"
     exon            357..416
                     /gene="Rpl13a"
                     /inference="alignment:Splign:2.1.0"
     exon            417..539
                     /gene="Rpl13a"
                     /inference="alignment:Splign:2.1.0"
     exon            540..652
                     /gene="Rpl13a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcggctgcc gaagatggcg gaggggcagg ttctagtatt ggatggccgg ggccatcttc
       61 tgggccgcct ggcggccatt gtggccaagc aggtactgct gggccgaaag gtggtggttg
      121 tacgctgtga gggcatcaac atttctggaa atttctacag aaacaagtta aagtatctgg
      181 cctttctccg aaagcggatg aacaccaacc cgtctcgagg cccctaccac ttccgagccc
      241 caagccgcat tttttggcgc actgtgcgag gcatgctgcc gcacaagacc aaaagaggcc
      301 aggctgccct ggaacgcctc aaggtgttgg atgggatccc tccaccctat gacaagaaaa
      361 agcggatggt ggtccctgct gccctcaagg ttgtgcggct gaagcctacc agaaagtttg
      421 cttacctggg gcgtctggct catgaggtcg ggtggaagta ccaggcagtg acagctactc
      481 tggaggagaa acggaaggaa aaggcaaaga tccattaccg gaagaagaag cagctcttga
      541 ggctaaggaa acaggcagaa aagaatgtgg agaagaaaat ctgcaagttc acagaggtcc
      601 tcaagaccaa tggactcttg gtgtgaaccc aataaagact gtttgtgcct caaaaaaaaa
      661 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
