LOCUS       NM_001109198             724 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ribosomal protein L12 (Rpl12), mRNA.
ACCESSION   NM_001109198 XM_001078515 XM_575115
VERSION     NM_001109198.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 724)
  AUTHORS   Zanivan,S., Maione,F., Hein,M.Y., Hernandez-Fernaud,J.R.,
            Ostasiewicz,P., Giraudo,E. and Mann,M.
  TITLE     SILAC-based proteomics of human primary endothelial cell
            morphogenesis unveils tumor angiogenic markers
  JOURNAL   Mol Cell Proteomics 12 (12), 3599-3611 (2013)
   PUBMED   23979707
REFERENCE   2  (bases 1 to 724)
  AUTHORS   Anger,A.M., Armache,J.P., Berninghausen,O., Habeck,M., Subklewe,M.,
            Wilson,D.N. and Beckmann,R.
  TITLE     Structures of the human and Drosophila 80S ribosome
  JOURNAL   Nature 497 (7447), 80-85 (2013)
   PUBMED   23636399
REFERENCE   3  (bases 1 to 724)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (bases 1 to 724)
  AUTHORS   Kuo,J.C., Han,X., Hsiao,C.T., Yates,J.R. 3rd and Waterman,C.M.
  TITLE     Analysis of the myosin-II-responsive focal adhesion proteome
            reveals a role for beta-Pix in negative regulation of focal
            adhesion maturation
  JOURNAL   Nat Cell Biol 13 (4), 383-393 (2011)
   PUBMED   21423176
REFERENCE   5  (bases 1 to 724)
  AUTHORS   Bayes,A., van de Lagemaat,L.N., Collins,M.O., Croning,M.D.,
            Whittle,I.R., Choudhary,J.S. and Grant,S.G.
  TITLE     Characterization of the proteome, diseases and evolution of the
            human postsynaptic density
  JOURNAL   Nat Neurosci 14 (1), 19-21 (2011)
   PUBMED   21170055
REFERENCE   6  (bases 1 to 724)
  AUTHORS   Anderson,C.J., Neas,B.R., Uchiumi,T. and Stafford,H.A.
  TITLE     Autoantibodies to the 20-kDa ribosomal proteins: identification,
            characterization, and new aspects on prevalence in systemic Lupus
            erythematosus
  JOURNAL   Clin Immunol 98 (2), 249-257 (2001)
   PUBMED   11161982
REFERENCE   7  (bases 1 to 724)
  AUTHORS   Uchiumi,T. and Kominami,R.
  TITLE     Binding of mammalian ribosomal protein complex P0.P1.P2 and protein
            L12 to the GTPase-associated domain of 28 S ribosomal RNA and
            effect on the accessibility to anti-28 S RNA autoantibody
  JOURNAL   J Biol Chem 272 (6), 3302-3308 (1997)
   PUBMED   9013569
REFERENCE   8  (bases 1 to 724)
  AUTHORS   Uchiumi,T., Wada,A. and Kominami,R.
  TITLE     A base substitution within the GTPase-associated domain of
            mammalian 28 S ribosomal RNA causes high thiostrepton accessibility
  JOURNAL   J Biol Chem 270 (50), 29889-29893 (1995)
   PUBMED   8530386
REFERENCE   9  (bases 1 to 724)
  AUTHORS   Suzuki,K., Olvera,J. and Wool,I.G.
  TITLE     The primary structure of rat ribosomal protein L12
  JOURNAL   Biochem Biophys Res Commun 172 (1), 35-41 (1990)
   PUBMED   1977388
REFERENCE   10 (bases 1 to 724)
  AUTHORS   Marion,M.J. and Marion,C.
  TITLE     Localization of ribosomal proteins on the surface of mammalian 60S
            ribosomal subunits by means of immobilized enzymes. Correlation
            with chemical cross-linking data
  JOURNAL   Biochem Biophys Res Commun 149 (3), 1077-1083 (1987)
   PUBMED   3426607
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474001.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_575115.2, XM_001078515.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ149955.1, BC166903.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..724
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p11"
     gene            1..724
                     /gene="Rpl12"
                     /gene_synonym="RL12"
                     /note="ribosomal protein L12"
                     /db_xref="GeneID:499782"
                     /db_xref="RGD:1565106"
     exon            1..125
                     /gene="Rpl12"
                     /gene_synonym="RL12"
                     /inference="alignment:Splign:2.1.0"
     CDS             89..586
                     /gene="Rpl12"
                     /gene_synonym="RL12"
                     /note="60S ribosomal protein L12"
                     /codon_start=1
                     /product="large ribosomal subunit protein uL11"
                     /protein_id="NP_001102668.1"
                     /db_xref="GeneID:499782"
                     /db_xref="RGD:1565106"
                     /translation="MPPKFDPNEIKVVYLRCTGGEVGATSALAPKIGPLGLSPKKVGD
                     DIAKATGDWKGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHNG
                     NITFDEIVNIARQMRHRSLARELSGTIKEILGTAQSVGCNVDGRHPHDIIDDINSGAV
                     ECPAS"
     exon            126..199
                     /gene="Rpl12"
                     /gene_synonym="RL12"
                     /inference="alignment:Splign:2.1.0"
     exon            200..298
                     /gene="Rpl12"
                     /gene_synonym="RL12"
                     /inference="alignment:Splign:2.1.0"
     exon            299..380
                     /gene="Rpl12"
                     /gene_synonym="RL12"
                     /inference="alignment:Splign:2.1.0"
     exon            381..467
                     /gene="Rpl12"
                     /gene_synonym="RL12"
                     /inference="alignment:Splign:2.1.0"
     exon            468..580
                     /gene="Rpl12"
                     /gene_synonym="RL12"
                     /inference="alignment:Splign:2.1.0"
     exon            581..724
                     /gene="Rpl12"
                     /gene_synonym="RL12"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttttcggctt tcggttcgga ggaggcaacg gtgcaacttt cttcggtcgt cccgaatccg
       61 ggttcatccg acaccagcca cctccaccat gccgcccaag ttcgacccca acgagatcaa
      121 agtcgtgtac ttgaggtgca ccggaggcga ggtcggcgcc acatccgcct tggcccctaa
      181 gatcggtcct ctgggtctgt ctcccaaaaa agttggtgat gacatcgcca aggctaccgg
      241 tgactggaaa ggcctcagga ttacagtgaa actgaccatc cagaacagac aggcccagat
      301 tgaggtggtg ccctctgcct ctgccctgat catcaaagcc ctcaaggagc caccaagaga
      361 caggaagaag cagaaaaaca ttaaacacaa tggaaacata acttttgatg agattgtcaa
      421 cattgcccgg cagatgagac accggtcttt ggccagagaa ctttctggaa ctatcaagga
      481 gatcctgggt actgcacagt ctgtgggctg caatgtggac ggccgccacc ctcatgacat
      541 catagatgac atcaacagcg gtgcggtgga gtgcccagct agttaagaag caacgagaag
      601 gggttgggaa tttagctcag tggtagagcg cttgccaagc ccaaggccct gggttcagtc
      661 cccagctccg gaaaaaaaaa agcaacaaga aaatatttaa ataaaagact atctgataaa
      721 ccag
//
