LOCUS       NM_001025739             935 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ribosomal protein L11 (Rpl11), mRNA.
ACCESSION   NM_001025739 XM_342949
VERSION     NM_001025739.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 935)
  AUTHORS   Slomnicki,L.P., Hallgren,J., Vashishta,A., Smith,S.C., Ellis,S.R.
            and Hetman,M.
  TITLE     Proapoptotic Requirement of Ribosomal Protein L11 in Ribosomal
            Stress-Challenged Cortical Neurons
  JOURNAL   Mol Neurobiol 55 (1), 538-553 (2018)
   PUBMED   27975169
  REMARK    GeneRIF: knockdown of the RP L11, which in nonneuronal systems
            mediates p53 activation downstream of ribosomal stress, protected
            neurons against inhibition of ribosomal biogenesis.
REFERENCE   2  (bases 1 to 935)
  AUTHORS   Morgado-Palacin,L., Varetti,G., Llanos,S., Gomez-Lopez,G.,
            Martinez,D. and Serrano,M.
  TITLE     Partial Loss of Rpl11 in Adult Mice Recapitulates Diamond-Blackfan
            Anemia and Promotes Lymphomagenesis
  JOURNAL   Cell Rep 13 (4), 712-722 (2015)
   PUBMED   26489471
REFERENCE   3  (bases 1 to 935)
  AUTHORS   Smetanina,N.S., Mersiyanova,I.V., Kurnikova,M.A.,
            Ovsyannikova,G.S., Hachatryan,L.A., Bobrynina,V.O., Maschan,M.A.,
            Novichkova,G.A., Lipton,J.M. and Maschan,A.A.
  TITLE     Clinical and genomic heterogeneity of Diamond Blackfan anemia in
            the Russian Federation
  JOURNAL   Pediatr Blood Cancer 62 (9), 1597-1600 (2015)
   PUBMED   25946618
REFERENCE   4  (bases 1 to 935)
  AUTHORS   Behrmann,E., Loerke,J., Budkevich,T.V., Yamamoto,K., Schmidt,A.,
            Penczek,P.A., Vos,M.R., Burger,J., Mielke,T., Scheerer,P. and
            Spahn,C.M.
  TITLE     Structural snapshots of actively translating human ribosomes
  JOURNAL   Cell 161 (4), 845-857 (2015)
   PUBMED   25957688
REFERENCE   5  (bases 1 to 935)
  AUTHORS   Voorhees,R.M., Fernandez,I.S., Scheres,S.H. and Hegde,R.S.
  TITLE     Structure of the mammalian ribosome-Sec61 complex to 3.4 A
            resolution
  JOURNAL   Cell 157 (7), 1632-1643 (2014)
   PUBMED   24930395
REFERENCE   6  (bases 1 to 935)
  AUTHORS   Peng,J., Kim,M.J., Cheng,D., Duong,D.M., Gygi,S.P. and Sheng,M.
  TITLE     Semiquantitative proteomic analysis of rat forebrain postsynaptic
            density fractions by mass spectrometry
  JOURNAL   J Biol Chem 279 (20), 21003-21011 (2004)
   PUBMED   15020595
REFERENCE   7  (bases 1 to 935)
  AUTHORS   Odintsova,T.I., Muller,E.C., Ivanov,A.V., Egorov,T.A., Bienert,R.,
            Vladimirov,S.N., Kostka,S., Otto,A., Wittmann-Liebold,B. and
            Karpova,G.G.
  TITLE     Characterization and analysis of posttranslational modifications of
            the human large cytoplasmic ribosomal subunit proteins by mass
            spectrometry and Edman sequencing
  JOURNAL   J Protein Chem 22 (3), 249-258 (2003)
   PUBMED   12962325
REFERENCE   8  (bases 1 to 935)
  AUTHORS   Chan,Y.L., Olvera,J., Paz,V. and Wool,I.G.
  TITLE     The primary structure of rat ribosomal protein L11
  JOURNAL   Biochem Biophys Res Commun 185 (1), 356-362 (1992)
   PUBMED   1599472
REFERENCE   9  (bases 1 to 935)
  AUTHORS   Uchiumi,T., Kikuchi,M. and Ogata,K.
  TITLE     Cross-linking study on protein neighborhoods at the subunit
            interface of rat liver ribosomes with 2-iminothiolane
  JOURNAL   J Biol Chem 261 (21), 9663-9667 (1986)
   PUBMED   3733691
REFERENCE   10 (bases 1 to 935)
  AUTHORS   Uchiumi,T., Kikuchi,M., Terao,K. and Ogata,K.
  TITLE     Neighboring proteins in rat liver 60 S ribosomal subunits
            disulfide-linked by hydrogen peroxide oxidation or cross-linked
            with dithiobis(succinimidyl propionate)
  JOURNAL   J Biol Chem 260 (9), 5669-5674 (1985)
   PUBMED   3988767
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC097372.1.
            
            On Jul 22, 2005 this sequence version replaced XM_342949.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC097372.1, CV108281.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..935
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..935
                     /gene="Rpl11"
                     /note="ribosomal protein L11"
                     /db_xref="GeneID:362631"
                     /db_xref="RGD:1308681"
     exon            1..493
                     /gene="Rpl11"
                     /inference="alignment:Splign:2.1.0"
     CDS             370..873
                     /gene="Rpl11"
                     /note="60S ribosomal protein L11"
                     /codon_start=1
                     /product="large ribosomal subunit protein uL5"
                     /protein_id="NP_001020910.1"
                     /db_xref="GeneID:362631"
                     /db_xref="RGD:1308681"
                     /translation="MRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARY
                     TVRSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFGIQEHI
                     DLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRISKEEAMRWFQQKYD
                     GIILPGK"
     exon            494..600
                     /gene="Rpl11"
                     /inference="alignment:Splign:2.1.0"
     exon            601..732
                     /gene="Rpl11"
                     /inference="alignment:Splign:2.1.0"
     exon            733..843
                     /gene="Rpl11"
                     /inference="alignment:Splign:2.1.0"
     exon            844..908
                     /gene="Rpl11"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtttggtgct ggggagcatc tgcgggtccc tactcaggac tggtgctcgc ttgcagacag
       61 cttgggaagg aggagggcag gtcgcgtagg ccgatgtttc ctgtagtttg tcattttaag
      121 gttacattgt attctctcct gtctgattgg ctttctataa gctcttgtgt ctattaccca
      181 gaaacatcga ccgccttagc attcaggctt actcagtgct cctccgcccc aaacactgag
      241 acctttttag tccttagtcc ataggattcg ggaccgtaga gatcagactg gagaagacat
      301 tggcttctcg actttgacgg ctgcgtttac tcttttctgc agcaagatca gggtgaaaag
      361 gagaacccca tgcgggaact tcgtatccgc aagctctgcc tcaatatctg cgtgggggag
      421 agtggagaca gactgacccg agcagccaag gtgttggagc agctcacagg ccagacccct
      481 gtgttttcca aagctagata caccgtcagg tcctttggca tccggagaaa tgagaaaatc
      541 gctgttcact gcactgtccg tggagccaag gcagaggaga ttctggagaa aggcctgaag
      601 gtgcgagagt acgaattacg gaagaataac ttctcagata ccggcaactt tggctttggg
      661 attcaggaac acattgacct aggcatcaaa tatgacccaa gcattggcat ctatggcctg
      721 gatttctatg tggtgctggg taggccaggt ttcagcatcg cagacaagaa gcgcagaaca
      781 ggctgcattg gggccaaaca cagaatcagc aaagaggagg ccatgcgctg gttccagcag
      841 aagtatgatg gcatcatcct tcctggcaaa taaactttat ccaaaggcca ataaagtttt
      901 ctcagaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//
