LOCUS       NM_001107414            7081 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus Rpgrip1-like (Rpgrip1l), mRNA.
ACCESSION   NM_001107414 XM_001065429 XM_226323
VERSION     NM_001107414.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 7081)
  AUTHORS   Wang,C., Li,J., Takemaru,K.I., Jiang,X., Xu,G. and Wang,B.
  TITLE     Centrosomal protein Dzip1l binds Cby, promotes ciliary bud
            formation, and acts redundantly with Bromi to regulate ciliogenesis
            in the mouse
  JOURNAL   Development 145 (6) (2018)
   PUBMED   29487109
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7081)
  AUTHORS   Lambacher,N.J., Bruel,A.L., van Dam,T.J., Szymanska,K.,
            Slaats,G.G., Kuhns,S., McManus,G.J., Kennedy,J.E., Gaff,K.,
            Wu,K.M., van der Lee,R., Burglen,L., Doummar,D., Riviere,J.B.,
            Faivre,L., Attie-Bitach,T., Saunier,S., Curd,A., Peckham,M.,
            Giles,R.H., Johnson,C.A., Huynen,M.A., Thauvin-Robinet,C. and
            Blacque,O.E.
  TITLE     TMEM107 recruits ciliopathy proteins to subdomains of the ciliary
            transition zone and causes Joubert syndrome
  JOURNAL   Nat Cell Biol 18 (1), 122-131 (2016)
   PUBMED   26595381
REFERENCE   3  (bases 1 to 7081)
  AUTHORS   Ghosh,A.K., Hurd,T. and Hildebrandt,F.
  TITLE     3D spheroid defects in NPHP knockdown cells are rescued by the
            somatostatin receptor agonist octreotide
  JOURNAL   Am J Physiol Renal Physiol 303 (8), F1225-F1229 (2012)
   PUBMED   22832925
REFERENCE   4  (bases 1 to 7081)
  AUTHORS   Mahuzier,A., Gaude,H.M., Grampa,V., Anselme,I., Silbermann,F.,
            Leroux-Berger,M., Delacour,D., Ezan,J., Montcouquiol,M.,
            Saunier,S., Schneider-Maunoury,S. and Vesque,C.
  TITLE     Dishevelled stabilization by the ciliopathy protein Rpgrip1l is
            essential for planar cell polarity
  JOURNAL   J Cell Biol 198 (5), 927-940 (2012)
   PUBMED   22927466
REFERENCE   5  (bases 1 to 7081)
  AUTHORS   Woo,J. and Lee,C.
  TITLE     Genetic association of the gene encoding RPGRIP1L with
            susceptibility to vascular dementia
  JOURNAL   Gene 499 (1), 160-162 (2012)
   PUBMED   22425971
REFERENCE   6  (bases 1 to 7081)
  AUTHORS   Tokue,S., Sasaki,M. and Nakahata,N.
  TITLE     Thromboxane A2-induced signal transduction is negatively regulated
            by KIAA1005 that directly interacts with thromboxane A2 receptor
  JOURNAL   Prostaglandins Other Lipid Mediat 89 (1-2), 8-15 (2009)
   PUBMED   19464661
REFERENCE   7  (bases 1 to 7081)
  AUTHORS   Wolf,M.T., Saunier,S., O'Toole,J.F., Wanner,N., Groshong,T.,
            Attanasio,M., Salomon,R., Stallmach,T., Sayer,J.A., Waldherr,R.,
            Griebel,M., Oh,J., Neuhaus,T.J., Josefiak,U., Antignac,C.,
            Otto,E.A. and Hildebrandt,F.
  TITLE     Mutational analysis of the RPGRIP1L gene in patients with Joubert
            syndrome and nephronophthisis
  JOURNAL   Kidney Int 72 (12), 1520-1526 (2007)
   PUBMED   17960139
REFERENCE   8  (bases 1 to 7081)
  AUTHORS   Delous,M., Baala,L., Salomon,R., Laclef,C., Vierkotten,J., Tory,K.,
            Golzio,C., Lacoste,T., Besse,L., Ozilou,C., Moutkine,I.,
            Hellman,N.E., Anselme,I., Silbermann,F., Vesque,C., Gerhardt,C.,
            Rattenberry,E., Wolf,M.T., Gubler,M.C., Martinovic,J.,
            Encha-Razavi,F., Boddaert,N., Gonzales,M., Macher,M.A., Nivet,H.,
            Champion,G., Bertheleme,J.P., Niaudet,P., McDonald,F.,
            Hildebrandt,F., Johnson,C.A., Vekemans,M., Antignac,C., Ruther,U.,
            Schneider-Maunoury,S., Attie-Bitach,T. and Saunier,S.
  TITLE     The ciliary gene RPGRIP1L is mutated in cerebello-oculo-renal
            syndrome (Joubert syndrome type B) and Meckel syndrome
  JOURNAL   Nat Genet 39 (7), 875-881 (2007)
   PUBMED   17558409
REFERENCE   9  (bases 1 to 7081)
  AUTHORS   Arts,H.H., Doherty,D., van Beersum,S.E., Parisi,M.A.,
            Letteboer,S.J., Gorden,N.T., Peters,T.A., Marker,T., Voesenek,K.,
            Kartono,A., Ozyurek,H., Farin,F.M., Kroes,H.Y., Wolfrum,U.,
            Brunner,H.G., Cremers,F.P., Glass,I.A., Knoers,N.V. and Roepman,R.
  TITLE     Mutations in the gene encoding the basal body protein RPGRIP1L, a
            nephrocystin-4 interactor, cause Joubert syndrome
  JOURNAL   Nat Genet 39 (7), 882-888 (2007)
   PUBMED   17558407
REFERENCE   10 (bases 1 to 7081)
  AUTHORS   Vierkotten,J., Dildrop,R., Peters,T., Wang,B. and Ruther,U.
  TITLE     Ftm is a novel basal body protein of cilia involved in Shh
            signalling
  JOURNAL   Development 134 (14), 2569-2577 (2007)
   PUBMED   17553904
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474037.2.
            
            [WARNING] On Oct 26, 2024 this sequence was replaced by
            NM_001107414.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_226323.4, XM_001065429.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..7081
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19p11"
     gene            1..7081
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /note="Rpgrip1-like"
                     /db_xref="GeneID:307724"
                     /db_xref="RGD:1311099"
     exon            1..59
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
     exon            60..151
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
     CDS             67..3861
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /codon_start=1
                     /product="protein fantom"
                     /protein_id="NP_001100884.1"
                     /db_xref="GeneID:307724"
                     /db_xref="RGD:1311099"
                     /translation="MSGPSDETAGDLPVKDTGLHLFGIGGLQETSTARTVKARQAVSR
                     VSREELEDRFLRLHDENILLKQHARKQEDKIKRMATKLIRLVNDKKRYERVGGGPKRL
                     GRDVEMEEMIEQLQEKVHELERQNEVLKNRLISAKQQLQVQGHRQTSYSRVQARTNTG
                     RRKASTTAGLQECLGKGIKVQNVDEAETVQPTLTKYSSGLLEEARGEIRNLENVIQSQ
                     RGQIEELEHLAEILKTQLKRKENEIELSLLQLREQQATDQRSNIRDNVEMIKLHKQLV
                     EKSNALSVIEGKFIQLQEKQRTLRISHDALMANGDELNMQLKEQRLKCCSLEKQLHSV
                     RFSERRVEELQDRINDLEKERELLKENYDKLYNSAFSAAHEEQWKLKEQQMKVQIAQL
                     ETALKSDLTDKAEVLDQLKTERDQNEKLVQENRDLQLQCLQQKQQLHELQNRMKFFNQ
                     ESDINVDDLSEALLLIKAQKEQKNGDLSFLEKVDSKINKDLDRSMKELQATHAETVQE
                     LEKTRNMLIMQHKINKDYQMEVETVTQKMENLQQDHELKVEQYVHLLDVRAARIQKLE
                     AQLKDIAYGTKQYKFKPEIMPDDSVDEFDETIHLERGENLFEIHINKVAFASDVLRAS
                     GDKELLTFCTYAFYDFELQTTPIVRGPCPEYNFTSQYLVHVNDLFLQYIQKNTVTLEL
                     HQAYSTDYETVAACQLRFHEILEKSGRIFCTTSLVGTKGDIPNFGTVEYWFRLRVPMD
                     QAIRLYRERAKALGYITSNFKKPEKMQLLSQQAATTAQISSPESTDGNLNELHITVRC
                     CTNLQSRARHLQPHAYVVYKFFDFPDHDTAIIPSSNDPQFDDYMCFPVPMNMDLDRYL
                     KSESLSFYVFDDSDIQENIYIGKVNVPLISLAHDRCISGIFELMDKDKHAAGTIQVIL
                     KWKFTYLPPSGSIPTEDLGRFVGREEPEAIQRRPPTSSGTEAVVTPKPKPRQRLTFVD
                     KKVSFVDTMPHPSPEASPPPKDIKHNSPEVGPETENSMPAVACPSKESSVAKVEENMG
                     KTQQGKEDDISFLSEGQLASQSVASSEDETEITEELEPEDEDRSASDSDDCIIPSSVS
                     TDTKKPSEEIRIEIIALSLNDSQITREDTVQRLFIECRFYSLPAEETPMSLPKPKSGQ
                     WVYYNYTHVLYLDKENNPAVRDVLKAVLQRRELPHRSVRFTVVSDPPEDEQDLECEDI
                     GVAHLDLVDVFQKGRDIIEQDIDVLDARTDGGSIGKLKVTVEALHALRSVYEQYRKDL
                     EA"
     exon            152..296
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
     exon            297..595
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
     exon            596..698
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
     exon            699..842
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
     exon            843..948
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
     exon            949..1095
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
     exon            1096..1169
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
     exon            1170..1309
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
     exon            1310..1416
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
     exon            1417..1467
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
     exon            1468..1647
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
     exon            1648..1765
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
     exon            1766..2218
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
     exon            2219..2370
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
     exon            2371..2749
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
     exon            2750..2940
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
     exon            2941..3024
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
     exon            3025..3120
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
     exon            3121..3274
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
     exon            3275..3345
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
     exon            3346..3529
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
     exon            3530..3614
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
     exon            3615..3748
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
     exon            3749..7081
                     /gene="Rpgrip1l"
                     /gene_synonym="RGD1311099"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcagaggctc gcgccctggg cgctatagca acggtaggta gctgaggggg aacgcggaga
       61 taagccatgt ctggcccaag tgacgagaca gcaggagacc tgccggtgaa agatacaggt
      121 ctacatctct ttggaattgg agggttacaa gaaacctcaa ctgcgcgcac agtgaaggct
      181 cgccaggcag tgtcacgtgt cagtcgcgaa gaactggaag acagattttt gcgtttgcat
      241 gatgagaaca tcttacttaa acagcatgcc cgcaagcaag aggataaaat taaaagaatg
      301 gccaccaagt taatacggct agttaatgac aagaaacgat atgagcgggt tggtggcggc
      361 cccaagcggc tgggacgaga tgtggaaatg gaagaaatga ttgagcagct gcaagaaaaa
      421 gttcatgagc ttgaaagaca aaatgaagtt ctcaaaaaca ggctaatatc agccaaacag
      481 cagctccaag ttcaagggca caggcagacc tcgtacagtc gtgttcaggc tcgcactaac
      541 accggacgta ggaaagcaag caccactgct ggcttgcagg aatgcctggg gaaaggtata
      601 aaagttcaga atgtagatga agcagaaact gtacaaccca cgctcacaaa gtacagcagt
      661 ggtttactcg aagaggccag aggagaaata agaaatttag aaaatgttat tcagtcacag
      721 agaggccaga tagaagagtt agagcatttg gcagagatcc tgaaaactca gttgaagaga
      781 aaagaaaatg agattgagtt atctcttctt cagcttcgag aacagcaagc tacagatcag
      841 aggtcaaata ttcgggacaa tgtagaaatg ataaagcttc ataaacaact agtggagaaa
      901 agcaatgctc tttcagtcat agaaggaaaa ttcattcagc ttcaagagaa gcaaagaaca
      961 ctcaggatca gccacgatgc cttgatggca aatggagatg agctaaacat gcagcttaag
     1021 gaacagcgac tgaagtgctg cagcctggag aagcagctgc actctgtcag gttttcagag
     1081 cggagagtgg aggagctgca ggatagaatt aatgatttag aaaaggaacg agaactttta
     1141 aaggaaaact atgataaact ttataacagt gccttcagtg ctgcccacga agagcagtgg
     1201 aagttaaagg agcagcagat gaaggtacag attgcccagc tcgaaaccgc cttaaaatct
     1261 gacctcacag acaaagccga agtccttgac caattaaaga ctgaacgaga ccaaaatgag
     1321 aagctggtgc aagagaacag agacctgcag ctgcagtgtc tgcagcaaaa gcagcagctg
     1381 catgagctcc aaaatcgcat gaagttcttc aaccaggaga gtgacatcaa tgttgatgac
     1441 ctcagtgaag cgctcctgct tataaaggct cagaaagaac aaaaaaatgg agatctttca
     1501 tttttagaaa aagtggacag caaaattaat aaagatctag atcgttccat gaaggagctt
     1561 caagcaactc atgcagaaac agtacaagaa cttgaaaaga caagaaatat gttaattatg
     1621 cagcataaaa taaataaaga ctatcagatg gaagttgaaa cagtgactca gaagatggaa
     1681 aatttgcaac aagatcatga actgaaagtg gaacaatatg ttcatcttct cgacgtcaga
     1741 gctgcacgca tccaaaagct tgaagcccag ctgaaggata ttgcctacgg cactaagcag
     1801 tacaaattta aaccagaaat catgccagat gactctgttg atgaatttga tgaaaccatc
     1861 cacctagaac gaggagaaaa tctatttgaa atccacatca acaaagtcgc ctttgcttct
     1921 gacgtcctgc gggcatctgg tgataaagag cttctcactt tctgtaccta cgctttctat
     1981 gactttgaac tgcagacaac tcccatcgtg cgaggccctt gcccagagta taacttcacc
     2041 tctcagtatc ttgtccacgt caatgactta ttcttgcagt acattcagaa gaacactgtc
     2101 actctggagc tccaccaagc ctacagcaca gattacgaaa cggttgcggc ctgtcagctg
     2161 agattccatg agattctaga aaaaagcggt agaatttttt gcacaacaag cttagttgga
     2221 actaaaggag acatcccaaa ttttggcaca gtagaatact ggtttcgatt aagagttccc
     2281 atggatcaag ctattcgact ttatcgagag cgggcaaaag cattaggata cataacatca
     2341 aattttaaga agccagagaa aatgcaattg ttgagtcagc aagcagccac aactgctcag
     2401 atcagttcac cagagtccac agacggcaac ttaaatgaac ttcacattac agtaagatgt
     2461 tgtaccaacc tacagtcccg agcacgccac ctacagccac acgcatatgt tgtgtacaag
     2521 ttctttgatt ttccagacca tgatacagcc attattccta gtagcaatga tccacagttt
     2581 gatgactaca tgtgtttccc agtgccaatg aatatggact tggatcgata ccttaagtca
     2641 gagtctctga gtttttatgt ttttgatgat agtgatatcc aggagaatat ttacatagga
     2701 aaagtcaatg tgcctctgat ttccctggca catgacaggt gtatctcagg aatatttgag
     2761 ttaatggata aggacaagca tgctgcagga accatccaag ttatattgaa atggaaattc
     2821 acttacctcc caccaagtgg gtcgatcccg actgaagacc tcggaaggtt cgttggcagg
     2881 gaagagccgg aggccattca gagacgacct ccaacgtcct ccggcactga ggcagtcgtg
     2941 acaccaaaac ctaaaccaag acaacgttta acatttgtgg ataaaaaggt ctcttttgtg
     3001 gataccatgc cacacccaag tcctgaggct tctcctcccc ctaaagatat aaagcacaat
     3061 tctccagaag tgggaccaga aacagaaaat agcatgccag ctgttgcatg tccttccaag
     3121 gaaagcagtg tggctaaggt agaagaaaac atggggaaaa cgcaacaagg aaaagaagac
     3181 gacatctctt tcctatctga gggccagctt gcatcacaaa gtgtggcttc ctctgaagat
     3241 gaaacagaaa taaccgaaga attggagcca gaagatgaag acagatccgc ttctgacagt
     3301 gatgactgta tcattccaag ttctgtctcc acagatacca aaaagccatc ggaagaaatt
     3361 cggattgaga ttatagctct gagccttaat gattctcaga taaccaggga ggacactgtt
     3421 cagcgactgt tcatcgagtg ccggttctac agtcttcccg ctgaggagac gcctatgtca
     3481 ctgcccaaac ccaagagtgg acagtgggtc tactataact atacccatgt gctctacctg
     3541 gataaagaga acaacccagc ggtgagagac gtcttaaaag ccgtactgca aaggcgggaa
     3601 ctgcctcaca gaagtgtgcg cttcaccgtg gtcagtgatc ctcccgagga tgagcaggac
     3661 ctagaatgtg aggacattgg cgttgctcac cttgacctcg tggatgtgtt tcagaaagga
     3721 agagacatca ttgagcaaga cattgatgtt cttgatgccc gaacagatgg tggcagcatc
     3781 ggcaaactga aggtgaccgt ggaagcgctt catgccctac ggtctgtcta cgagcaatac
     3841 agaaaggact tggaggcttg aaggaagctg ttccagaggc atcctacttc taagaaaatg
     3901 ttcacatgaa agctcaaaga tgagattctg agtaatcact ggtgtatgta atctataatt
     3961 catggggagc tgggagagcg cctgggttta ggcttgaatg ttcaagtttt gtatagtttt
     4021 tgtgtttgtt tatttttcta tccactcctc cccatgactg ccacccctta ggacttcagt
     4081 gctcctgagt ggactacctt atcaataatt tatagcaaca tgatagcatg aaacatctat
     4141 ttgcatttgc atcattttct tatgaagaac tgggagtagt tcccattttt atttttcata
     4201 agtaaaagcc taaaatctta ggaaaccaat gaaaaagaaa tgctttttat gttatcccta
     4261 attgtcccac tcaatggaac gcctctgatt agcctcatta agacttttat actgtgaaga
     4321 ttttattaga agcaatatat gaaaattact tggattaatg tgttaatctt tctctttaaa
     4381 atgctaatat ctactttatg cacattaaag ctcagtgtgc attttctttg atgcacacag
     4441 tttctatcaa ttaaatataa agaaggagac ttggcaccaa cctactaaat tactcccagt
     4501 aatttgtttt tttcataaac attatagttg ttccaggtta tgtggtatca gtgtgttttt
     4561 aatgctgata caagatccag gattgtattc atataaagaa gatatagata gatagagaca
     4621 catacatgca tacatacata catacataca tacattacat acatacatgc atgcacacat
     4681 acatacttgc atacatacat gcacaggaaa tttatatttt acaaattaaa gttaaattac
     4741 atagaaaaaa taaagtatgg ctcaaattct aaaatgctta gacatgaaag gtgacccttt
     4801 tatcattttt aaaaacttac atcaagcttc tacaatgctg ggatgtatct ggatatccag
     4861 actctcaaaa agcagctcca aaagttaatt tctacctttt acacagtctc gctgaagagt
     4921 ttaattgata tttttaatgg agctgtgaat cagtgctgca aaagaattgt ctctgggggt
     4981 ctgagatata atgcatttca ttttttaatt tactttttta tttgtcattt tcttcaaagg
     5041 atttttatag gctgtgggtt ttcactgttt gcaaacaggc tattcctttt taagcatatg
     5101 taaagtattc agggagataa gtaatttatt aaaatctacc taatttgccg tgctatatta
     5161 aatctctgct tcagtgatca cagaccattt catttagaga attaggcatt ccctctttgt
     5221 gtgattaaag tcctggaaaa tgagttcttt gctcctattt gtgaacattc aaagcctgct
     5281 aatggcagga agatggaaca gattatgaga caattcatta cagttcaaca gggaaagcag
     5341 ctataatgca gaaatgcgag tgtgaatatc agtgtatagc tgagccatct gtgctcggac
     5401 agcttcgctc atgactcctc cttgagaggc tttgaaatga catccgtacg atattaattt
     5461 gttggcgcac tttgtgggac cagtagagta taatctgacc acagaactct ataaactctg
     5521 tctgtaccat tgggcatccc tgtcctcagg cccgccatct ccaagaggaa tcttgctctc
     5581 atcagactct gaaaatctca aaacaactca ttcctctgga accttctagt gaccacagac
     5641 atctgcagac aaagcctctc cagttctagt aaacaaccac atgtttgttg tcactttagc
     5701 tggctctgag ctcatcttct tggcctccct ttctagcttt ctttggcttt gtgcagctac
     5761 agtgtcatta aggcccataa tattccctgc agtaatttaa agcagacaga ttataccctg
     5821 ggattagctg agtggttttc gagacattta ttgtggtatg ctcctaggag gcatgcatta
     5881 ttgttttaaa atgttatatc caaaactaaa taatgctttc ctcagggacg aaaatgggat
     5941 ggtgctgctt cttagcatct ttaagtggag acagggaagt tttaatccga aaaccttgta
     6001 caagtgagtc ggctgtgtag aatttacacc tcacgtgaaa tcgtggatca tccaggcttc
     6061 ccttaccttt gtatatcctg gctctaaaat tctcagcctc agactcctac ggatgttccc
     6121 atgctagctt cacatgtaat ggtgactaac aggttctgaa gggagagacc aagtgagtgt
     6181 gctcccttga agtccactgg catctttgtc tagacatgtg ttagccagag ttcactgaaa
     6241 agttcatctc cgttggttca aagtgctgtg ctgtctgtcc tctgtgaacc aggcttgctc
     6301 tgctgagatt gctgggcagt gagggctctc gcgcacacag acacagccct ggaggagagc
     6361 atgcagctct caataacgaa cggcacatac actcagcacc ctgggagcta taatgctttt
     6421 agtgtggaaa tataaataga gatgtgatgt ggcatgtggg caagtgtatt atacatggtt
     6481 ttttgcctac tgtagtagaa atgtcaagtt cccagccact gtcatgagaa gcagttgaca
     6541 aaaataagtt ttatggttta cagtgtggtt tacgtagaga acatttctct tcactcttgg
     6601 tttcaacatg ttttctgaat tatcatggtt tgttgccatt taacttaaat tagttttttt
     6661 aagaataaat agagactatg tttaatcaaa taaagaaagg ccacattgaa attctgctgc
     6721 tcctgccatt catttgttac cacaaaacac aaataatttc tatgtgtcat aaagaagcgt
     6781 gggctgagac gtggtcatgt gatttggggg gctctgcgtg caccaatgtt cccacaacaa
     6841 aacataaatt attttagtaa tctgacatca agagctgtga caatgaaaac cagctcttac
     6901 acatgttcta acaagaatct gattaacatt tttgtggata tggaaaataa ctttttttta
     6961 gtcaagctgg cactgttgct gaatgtggaa tgatttccgt atgtacagga ttgcaaaatg
     7021 tgaatcatgt ctgtgaacaa atacgagaag aaaatgtgat ctttgtgcaa cacaaaacac
     7081 c
//
