LOCUS       NM_001013987            2197 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus RNA polymerase II associated protein 2 (Rpap2),
            mRNA.
ACCESSION   NM_001013987 XM_223142
VERSION     NM_001013987.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2197)
  AUTHORS   Jeronimo,C., Bataille,A.R. and Robert,F.
  TITLE     The writers, readers, and functions of the RNA polymerase II
            C-terminal domain code
  JOURNAL   Chem Rev 113 (11), 8491-8522 (2013)
   PUBMED   23837720
  REMARK    Review article
REFERENCE   2  (bases 1 to 2197)
  AUTHORS   Egloff,S., Dienstbier,M. and Murphy,S.
  TITLE     Updating the RNA polymerase CTD code: adding gene-specific layers
  JOURNAL   Trends Genet 28 (7), 333-341 (2012)
   PUBMED   22622228
  REMARK    Review article
REFERENCE   3  (bases 1 to 2197)
  AUTHORS   Egloff,S., Zaborowska,J., Laitem,C., Kiss,T. and Murphy,S.
  TITLE     Ser7 phosphorylation of the CTD recruits the RPAP2 Ser5 phosphatase
            to snRNA genes
  JOURNAL   Mol Cell 45 (1), 111-122 (2012)
   PUBMED   22137580
REFERENCE   4  (bases 1 to 2197)
  AUTHORS   Ni,Z., Olsen,J.B., Guo,X., Zhong,G., Ruan,E.D., Marcon,E.,
            Young,P., Guo,H., Li,J., Moffat,J., Emili,A. and Greenblatt,J.F.
  TITLE     Control of the RNA polymerase II phosphorylation state in promoter
            regions by CTD interaction domain-containing proteins RPRD1A and
            RPRD1B
  JOURNAL   Transcription 2 (5), 237-242 (2011)
   PUBMED   22231121
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC088426.1.
            
            On Apr 20, 2005 this sequence version replaced XM_223142.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088426.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2197
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p22"
     gene            1..2197
                     /gene="Rpap2"
                     /gene_synonym="RGD1309034"
                     /note="RNA polymerase II associated protein 2"
                     /db_xref="GeneID:305120"
                     /db_xref="RGD:1309034"
     exon            1..75
                     /gene="Rpap2"
                     /gene_synonym="RGD1309034"
                     /inference="alignment:Splign:2.1.0"
     CDS             3..1832
                     /gene="Rpap2"
                     /gene_synonym="RGD1309034"
                     /EC_number="3.1.3.16"
                     /note="putative RNA polymerase II-associated protein 2"
                     /codon_start=1
                     /product="RNA polymerase II subunit B1 CTD phosphatase
                     Rpap2"
                     /protein_id="NP_001014009.1"
                     /db_xref="GeneID:305120"
                     /db_xref="RGD:1309034"
                     /translation="MADSAVPYSLGPSARASSTHRVATGTKQTSALKRRDASKRQAEL
                     EAALQRKVESERRAVRLVEQLLEENITEEFLKECGMFITPAHYSDVVDERAIIKLCGY
                     PLCQKKLGVIPKQKYRISTKTNKVYDITERKSFCSNFCYKASKFFEAQIPKTPVWVRE
                     EERPPEFQLLKKGQSGCSGEVVQFFRDAVTAADVDAYGAFDAQCEPASSSTWSERASD
                     ERASDEEGPGFVSSLLPGNRPKAVGTKPQPHRQSSTVKKKAAQKMTSKHGEQTVSEVT
                     EQLSNCRLDSQEKVATCKLPAKKENTQISSPGPLCDRLNTSTVSENKHSVSQVTLVGI
                     SKKSAEHFRSKFAKSNPGSGSASGLVQVRPEVAKANLLRVLKDTLTEWKTDETLKFLY
                     GQDHGSVCLQPSAASGPDEELDEDDISCQAQNTLDETLPFRGSDTAIKPLPSYESLKK
                     ETEMLNLRVREFYRGRCVLNEDSTKSQDSKENELQRDPSFPLIDSSSQNQIRRRIVLE
                     KLSKVLPGLLGPLQITMGDIYTELKNLVQTFRLSNRNIIHKPVEWTLIAVVLLSLLTP
                     ILGIQKHSPKNVVFTQFIATLLTELHLKCEDLENLAMIFRTSC"
     exon            76..121
                     /gene="Rpap2"
                     /gene_synonym="RGD1309034"
                     /inference="alignment:Splign:2.1.0"
     exon            122..236
                     /gene="Rpap2"
                     /gene_synonym="RGD1309034"
                     /inference="alignment:Splign:2.1.0"
     exon            237..335
                     /gene="Rpap2"
                     /gene_synonym="RGD1309034"
                     /inference="alignment:Splign:2.1.0"
     exon            336..401
                     /gene="Rpap2"
                     /gene_synonym="RGD1309034"
                     /inference="alignment:Splign:2.1.0"
     exon            402..490
                     /gene="Rpap2"
                     /gene_synonym="RGD1309034"
                     /inference="alignment:Splign:2.1.0"
     exon            491..526
                     /gene="Rpap2"
                     /gene_synonym="RGD1309034"
                     /inference="alignment:Splign:2.1.0"
     exon            527..1445
                     /gene="Rpap2"
                     /gene_synonym="RGD1309034"
                     /inference="alignment:Splign:2.1.0"
     exon            1446..1540
                     /gene="Rpap2"
                     /gene_synonym="RGD1309034"
                     /inference="alignment:Splign:2.1.0"
     exon            1541..1621
                     /gene="Rpap2"
                     /gene_synonym="RGD1309034"
                     /inference="alignment:Splign:2.1.0"
     exon            1622..1690
                     /gene="Rpap2"
                     /gene_synonym="RGD1309034"
                     /inference="alignment:Splign:2.1.0"
     exon            1691..1837
                     /gene="Rpap2"
                     /gene_synonym="RGD1309034"
                     /inference="alignment:Splign:2.1.0"
     exon            1838..2173
                     /gene="Rpap2"
                     /gene_synonym="RGD1309034"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccatggcgga ctctgctgtt ccttactctc tgggcccaag tgcccgggct tccagcaccc
       61 accgagtcgc taccggtact aaacagacca gtgccctgaa acgaagagat gcgtctaaaa
      121 gacaagcgga actggaagct gccctgcaaa ggaaggtgga gtctgagagg agagctgtac
      181 gcctcgtaga gcagctcctg gaggagaaca tcacagaaga attcctgaag gagtgtggga
      241 tgttcatcac accggctcac tacagcgacg ttgtggatga gcgggccatc attaaactct
      301 gtggctatcc tttatgtcag aagaagctag gggttatacc aaaacagaaa taccggattt
      361 ctactaaaac caataaagtc tatgatatta ctgaaagaaa gtctttctgc agcaattttt
      421 gttacaaagc atctaaattt tttgaagcac agattcccaa aactccagta tgggttcgag
      481 aggaagagag gcctcctgaa tttcagctgc tgaagaaagg acaaagtggc tgttctggag
      541 aggtcgtaca gttcttcaga gacgccgtta cagcagcaga tgtcgatgct tatggtgcct
      601 ttgatgcaca gtgtgaacct gcttcctcca gcacttggag cgagcgtgcc agcgacgagc
      661 gtgccagcga tgaggagggg ccaggctttg tttcttctct tctcccagga aacagaccga
      721 aggccgtggg cacaaaacca cagccacaca gacaaagcag caccgtgaag aagaaggctg
      781 ctcagaaaat gacctccaag cacggagaac agaccgtgtc agaggtcacg gagcagttgt
      841 ctaattgtag attagatagt caggagaaag tagctacttg taaacttcct gcaaagaaag
      901 aaaacactca gatttcttca cctggccctt tgtgtgacag attaaatact tcaacagttt
      961 ctgaaaataa acacagtgta tcacaagtta ctcttgtggg gataagcaag aagagtgctg
     1021 agcatttcag gagcaaattt gccaaatcta acccagggtc tgggtcagcc tctggtttgg
     1081 tgcaggtgcg tcctgaggtc gcaaaggcaa atttactccg agttctaaag gacaccctga
     1141 ctgaatggaa gacagacgaa acactgaagt ttttatatgg ccaagaccat ggttctgtgt
     1201 gcctgcaacc ctctgcagcc tctgggcctg atgaagaact tgatgaagat gacataagct
     1261 gtcaagctca gaacaccttg gatgagacac tccccttcag aggctcagat acagccatta
     1321 agccactgcc aagttatgag agcctgaaaa aggaaacaga gatgttgaac ctgagggtca
     1381 gggagttcta cagaggacgc tgtgttttaa atgaagacag taccaagtct caggactcaa
     1441 aagagaatga gcttcagcgt gatcccagct tccccctgat tgattcgagt tcccagaacc
     1501 agattagaag acggattgtt cttgaaaaat tgagcaaagt attgcccggc cttttgggtc
     1561 ctcttcagat tacaatggga gatatttaca ctgaacttaa aaaccttgtt cagactttca
     1621 gattatcaaa tagaaacatt atccacaaac ctgtggagtg gactttaatc gccgtggtct
     1681 tgctgtcact gttgacacca attctcggca ttcagaagca ttctccaaaa aatgtggtat
     1741 ttacacagtt tatagccacc ctgctgacag aattgcatct aaaatgtgaa gatctggaaa
     1801 acttagccat gatatttaga accagctgct aacaatgata taactttgga agacagaaga
     1861 tgaatgcttc tcaccatacc tagagtttta gccagttagg gtccatgggt gactgatgac
     1921 taagtgtgta acttcctcag acgcagaaaa gccatgcccc agcaagaagg aagctcttac
     1981 atctagaccc ttgaaacaca ggatatgagg gaaaaatgaa gtcttaaatt gaaatttgag
     2041 tgaatgttag agaaaatgta attattcttt ttgattatag ccaaaactta agaaaatgat
     2101 atctgtggca tattgtaaac tctatcatac aaataacagc aaagttagat caataaatgt
     2161 gatcttcagt gaaaaaaaaa aaaaaaaaaa aaaaaaa
//
