LOCUS       NM_001421085            6557 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus RP1 like 1 (Rp1l1), mRNA.
ACCESSION   NM_001421085 XM_017599900
VERSION     NM_001421085.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6557)
  AUTHORS   Davidson,A.E., Sergouniotis,P.I., Mackay,D.S., Wright,G.A.,
            Waseem,N.H., Michaelides,M., Holder,G.E., Robson,A.G., Moore,A.T.,
            Plagnol,V. and Webster,A.R.
  TITLE     RP1L1 variants are associated with a spectrum of inherited retinal
            diseases including retinitis pigmentosa and occult macular
            dystrophy
  JOURNAL   Hum Mutat 34 (3), 506-514 (2013)
   PUBMED   23281133
REFERENCE   2  (bases 1 to 6557)
  AUTHORS   Yamashita,T., Liu,J., Gao,J., LeNoue,S., Wang,C., Kaminoh,J.,
            Bowne,S.J., Sullivan,L.S., Daiger,S.P., Zhang,K., Fitzgerald,M.E.,
            Kefalov,V.J. and Zuo,J.
  TITLE     Essential and synergistic roles of RP1 and RP1L1 in rod
            photoreceptor axoneme and retinitis pigmentosa
  JOURNAL   J Neurosci 29 (31), 9748-9760 (2009)
   PUBMED   19657028
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000015.1.
            
            On May 10, 2023 this sequence version replaced XM_017599900.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360190.580932.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760475 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-657               JAXUCZ010000015.1  42435803-42436459
            658-799             JAXUCZ010000015.1  42439898-42440039
            800-6557            JAXUCZ010000015.1  42441408-42447165
FEATURES             Location/Qualifiers
     source          1..6557
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p12"
     gene            1..6557
                     /gene="Rp1l1"
                     /note="RP1 like 1"
                     /db_xref="GeneID:683404"
                     /db_xref="RGD:1586886"
     exon            1..657
                     /gene="Rp1l1"
                     /inference="alignment:Splign:2.1.0"
     CDS             22..5604
                     /gene="Rp1l1"
                     /note="retinitis pigmentosa 1-like 1"
                     /codon_start=1
                     /product="retinitis pigmentosa 1-like 1 protein"
                     /protein_id="NP_001408014.1"
                     /db_xref="GeneID:683404"
                     /db_xref="RGD:1586886"
                     /translation="MNSTPGDTRDAPAPSHPAPSHRQCLLPSVAHTPSVTEVTPAKKI
                     TFLKRGDPQFAGVRLAVHQRTFKTFSALMDELSQRMPLSFGVRSVTTPRGLHGLSALE
                     QLQDGGCYLCSDRKPPKTPRESGRLQRKSPPAGRSQVSQGGHEAPETSSYSWKNPMAP
                     RRLTLVKNGYPGCQQTVVLSHKNTRNLAGFLSKASELLRFPVKQVYTTHGKKVDSLQT
                     LLDGPSLLVCAGNEAFRRLEMENDRGNRTRMVSGVTARSERGCWGPNAKQSVIHSRGR
                     SGGKLRQFSLMSERSGLSDHPASGHQAWAGPALDRCPQDTPAPPGSLVAADDVEKKVC
                     MNEDGSLSVEMKVRFQLLGEDTLRWSQRVGHASVFTAATGEDRDLREADRLCCRQEGY
                     PWGVLEPGAQGLGPHDGGCQGAFDVGQQSRPSYDIWRNPLTAPEGTGPTPRRRWGLAK
                     LSRCWREGTNDRKGHDKANASPVSTPRHPGSVQPGSCCLWTPEVETGSDTLRPVSSAS
                     SRSETDLESGEDPCLEDTGPCGLRLQTQSIDRALSDTSASAESREESCEGGGQLHRGS
                     SQARVMASQGQATRGDNPCISTQRHLSLNHTGLQTKKDRQSASCQEVRGDPVLRLPLV
                     PRHSGSRDTQRDALPAPACAPAQRRQRKQKRPAGVVCLPSVSIPHQVAQKGHARQCHC
                     CRDTQSSGDTALQMTMPMEREQACPGSPAPQFPSNSPRAGNQAPECLRPPFSSSLDFQ
                     EPQATSIAMSDSDCMSSFCHPSTRSAEPAEDSKCQAPSSTPTPIHRGEVGYLWDKAGS
                     TPEPFSSSVLLNRWPEADLRTYQNFGCLQVAPTSTLATPSSQTQASISEACLGDNSSC
                     PTPPQDQICSRREPASSNSTHSDHGRADGYTGPRRTLPGMPLGIRGSLEEQEGDGGVT
                     PSALPYTSPDAVVREWLGNIPEKPALMTYEVADETIEVPSEGPEGPKEDLGDGCSLKV
                     FGELTQARQQMLEGVTDEHPEPAGVPAGPGSVCCKLGGDMHSDATSVERLKAPAEAGT
                     GEGTTVERGVSLCALPTRVSASTQIMKALLGSKPGRPSSLPEVSSTVAQRLSCSAGAL
                     IACLAKLHFFDEDLGPLDGKRRLEESPKYQEMLNISQTLWPGSELGQGQLDFSLRRLT
                     SHQALLGTEDFTPTSSSGVDVSSGSGGSGEGSVPCVMDSTLASKKIDLPLKIPSQRPD
                     SRNQGYPEIVSPSTVSSGSQMRACTTSGEEAGKGGRKQTWGSAPEQSVENKVPEGDAQ
                     LEETEGRARERLQENSVLGEGLPEEGTRVCSQGMLAANSRDGAGSPEDTRVPNDEVGT
                     DGGLWPLDGREDPTESPCHFEESNSRVSERQSAHVPELGLDVRGGKQACVKASSETRE
                     TNTSIAHRGTLDPDPIWVSKLLKKIEKAFMAHLTDATAELRARWNLHDNNLLDQMVTE
                     LEQDVGQRLQASTVREVRKIQSRAGRMFPEPPREALRGQSSLQTEQRRRRLQGLRNLS
                     AFPGQGPLSFTLEDGATLGTALGTRSGAGLVEDEFCPCEICLKKKRTPRFPKDSTTVS
                     GAPVRKAFDLQQILQSKKDGSSNREAMEVSPQKTGMMLSQEDPRTVQGADEKQELRLA
                     QGLGVAEGEEGEGKQRMRAEEDTEFSKAEGDGCHAPKEDATTKEDGKICIGTAQDGQQ
                     LEGTEIGKEETLHQSFRDGDTSEAPARQGGHSVESQEASREGQPEVEGRNPDEKEESS
                     WVSSEESQGRVGSENNSLDQEGRLQDHHQRPGPQSHHAARSSRAMSLDNCSQVSQKGS
                     DRDFPSGDLKYNKAKNSGVLPAERKVPMMYPESSSSEQEAPSSPRPPKQEKGEDGRSA
                     CTQVGGRVDGFGQDDLDF"
     exon            658..799
                     /gene="Rp1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            800..6557
                     /gene="Rp1l1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agctgtctgg gcctccacat catgaacagc accccaggag acacgaggga tgctcctgcc
       61 ccaagccacc ctgcaccaag ccaccggcag tgtctcctgc cctctgtggc tcacactccc
      121 tctgttactg aagtgacacc agccaagaag ataaccttcc tcaagcgagg agacccccag
      181 tttgctgggg ttcgcctggc tgttcaccag cgcactttca agaccttcag cgccctaatg
      241 gatgagctgt ctcagcgcat gcctctttcc tttggggtgc gttctgtcac cacaccccgg
      301 ggattgcatg gcctcagtgc cctggagcag ttgcaagatg ggggttgcta cctctgctct
      361 gatagaaagc cccctaaaac tcccagagag tcaggccggc ttcaaaggaa aagcccccct
      421 gctgggcggt cacaggtttc ccaaggtggg cacgaagctc cagaaacatc ctcctattcc
      481 tggaaaaatc ctatggcccc aagaaggttg accctggtaa agaatggata tcctggatgc
      541 cagcagacag tggttctcag tcacaagaat accaggaacc tggcaggctt cctcagcaaa
      601 gcctctgagc ttctgcgctt tcccgtcaag caggtgtaca cgacccatgg gaagaaggtg
      661 gactctctgc agacactcct ggacggcccc tccctgctgg tatgtgctgg gaatgaggcc
      721 ttcagacgtc tggagatgga aaatgacaga gggaacagga ccagaatggt atctggtgtg
      781 actgcaagga gtgaacgtgg ctgctgggga ccgaacgcca agcagagtgt catacactca
      841 aggggcaggt ctggcggcaa gctgcggcag ttttccttga tgtcagagag gtctggtctc
      901 agtgaccatc cagcatccgg tcatcaagcc tgggcaggtc ctgctttgga caggtgccct
      961 caggacacgc ctgccccacc tggttccttg gtggctgctg atgatgtgga gaagaaggtc
     1021 tgcatgaatg aagacggcag tctgtctgtg gagatgaaag tccgcttcca gttactgggg
     1081 gaggacaccc tgaggtggtc ccagagggtg gggcatgcca gtgtcttcac agcagccact
     1141 ggagaggatc gggacctgag ggaggctgac aggctctgtt gcagacagga gggctaccct
     1201 tggggcgtct tagaacctgg ggcacaggga ctgggtcccc atgatggagg atgccaggga
     1261 gcctttgatg tgggccagca gtcacggccc agctatgaca tatggaggaa tcccctgaca
     1321 gcccctgagg gcacagggcc aactcctcgt aggagatggg gtctggctaa gctctctaga
     1381 tgctggagag agggaaccaa tgataggaaa ggacatgaca aggctaatgc cagcccagtc
     1441 tcaactccca ggcaccctgg aagtgtccag ccaggctcct gttgtctttg gactcctgaa
     1501 gttgaaacag gcagtgacac cttgcgtcca gtctcctcag cttcttcccg gagtgagact
     1561 gacctggaat ctggtgagga cccctgccta gaggacaccg gaccctgtgg cttgagactt
     1621 cagacccaaa gtatagacag ggccctttct gatacatcag ccagtgccga gtctcgtgag
     1681 gagtcttgtg agggtggtgg tcagctccac agaggctcaa gccaggcaag ggtcatggct
     1741 tcccaggggc aagccactag aggtgataac ccctgtattt ccacccagag gcacttatct
     1801 ttgaaccaca cgggtcttca gacaaagaag gacagacaga gcgccagctg ccaggaggtc
     1861 aggggtgatc ctgtactgag actgcccctg gttccacgcc attctggctc tcgggacaca
     1921 cagagagatg ccctcccagc tcctgcctgt gccccggccc agcggaggca gagaaagcag
     1981 aagaggccag ctggtgttgt gtgcttgcct agtgtctcta tccctcacca agtagcccag
     2041 aaaggccatg ccaggcagtg tcactgttgc agggacactc agtcctcagg ggacacagcc
     2101 ttgcaaatga caatgcctat ggaaagagag caagcctgcc caggaagccc ggcaccacaa
     2161 tttccttcaa actcacccag ggctgggaat caggcccccg agtgtctgag acccccattc
     2221 tccagctctc ttgattttca ggaaccacaa gccaccagca tcgccatgag tgactcagac
     2281 tgtatgtcca gcttttgtca tcccagcact cgctctgcag agccagcaga ggatagcaag
     2341 tgccaggctc cctcatcaac tcctacacct atccacagag gagaggttgg ttatctgtgg
     2401 gacaaggcag ggagcacccc tgagcctttc tcatcctctg tgctactgaa cagatggcct
     2461 gaggcagatc taagaaccta ccaaaatttc ggctgcttac aggttgcacc gacttctacc
     2521 cttgcaaccc ctagcagtca gacgcaggcc tccatctctg aggcctgctt gggggacaat
     2581 agttcctgcc caactccacc ccaggatcaa atatgttcta gaagggagcc tgcaagcagc
     2641 aatagtaccc acagtgacca cggtcgagcc gatggctaca ctgggcccag gaggactctt
     2701 ccggggatgc cccttggcat caggggaagc cttgaggaac aggaagggga tggtggtgtg
     2761 acgcccagtg ctctgcctta cacctctcca gatgctgtgg ttcgtgagtg gctaggcaac
     2821 atcccagaaa agccagcact catgacatat gaggtggcgg atgagaccat agaggtgccc
     2881 agtgagggcc cagaaggtcc caaggaggac ctgggtgatg gctgttcttt gaaagtcttt
     2941 ggggaactga ctcaggccag acagcagatg ctagaagggg ttactgatga gcacccagag
     3001 ccagcaggag tccctgcagg acctggttct gtgtgctgca aactgggagg tgatatgcat
     3061 tcagatgcaa catcagttga aaggctcaag gctcctgcag aagctggaac aggagaaggg
     3121 accacagtgg agcgtggtgt gagcctgtgt gcactcccca ccagggtctc agcctctaca
     3181 cagatcatga aggccctgct gggctccaag ccaggccggc ccagcagtct accagaagtc
     3241 tctagcacag tagcccagag actcagctgc tcggctgggg ccctcattgc ctgccttgcc
     3301 aagctccatt tttttgatga ggatctggga cctctggatg gcaaacggag gcttgaagag
     3361 tcccctaagt accaggagat gctcaacatc tcccagacgc tgtggcctgg aagtgagctt
     3421 gggcagggcc agctggattt cagcctcagg aggctcactt cacaccaggc tctgctgggg
     3481 actgaggact tcactcccac ctcctcctct ggcgtggacg tgagcagtgg ctctggaggc
     3541 tcaggtgagg gcagcgtgcc ctgtgtcatg gatagtaccc tggcttccaa gaagatagat
     3601 ttgcctttga aaatcccctc tcaaaggcct gattccagga accaggggta cccagagata
     3661 gtgagtcctt ccacagtctc atccggctcc cagatgaggg cttgtaccac cagcggggaa
     3721 gaggcaggca aaggaggcag gaagcagacg tggggcagtg ccccagaaca gtcagtcgaa
     3781 aacaaggtgc cggaagggga tgcacagtta gaagaaacag aagggagagc aagagaaagg
     3841 ctacaggaaa acagtgtcct cggagaaggg cttccagaag aagggactag ggtctgcagc
     3901 cagggaatgc ttgcagctaa ctctcgagat ggagcaggtt ctccagaaga cacaagagtg
     3961 ccaaacgatg aagtaggaac tgatggagga ctgtggcccc tagatgggag agaggatccc
     4021 acagagtccc cttgccattt cgaggagagc aactcaaggg ttagtgagcg tcaaagtgct
     4081 cacgtgccgg agctgggatt ggacgtaagg ggcggcaagc aagcctgcgt caaggccagc
     4141 tcagaaacca gggagacgaa cacatccata gcccacaggg gaactctgga ccctgaccca
     4201 atctgggtgt ccaagctgct gaagaagata gagaaagcct ttatggctca cctaactgat
     4261 gccacagctg aactccgagc ccgatggaat ctccatgaca acaacctgct ggaccagatg
     4321 gtaacagagc tggagcagga tgtgggccag cggctgcagg caagcactgt cagggaagtc
     4381 aggaagatcc agagccgggc agggaggatg tttccagagc ccccccggga agccctcaga
     4441 ggccagtctt ctctacaaac agagcaacgt cggcgtcgcc tccagggcct gcgtaacctg
     4501 tcggccttcc ctggccaggg ccccctctcc ttcactctgg aggatggggc cactctgggc
     4561 acagccttag ggaccaggtc aggtgcaggg cttgtggagg atgagttctg tccctgtgaa
     4621 atctgtctga agaagaagag gacccctaga ttcccaaagg atagcacaac agtctctggt
     4681 gcacccgtca gaaaggcctt tgacctacag caaattctac agagcaaaaa ggacggaagt
     4741 agcaatagag aggccatgga ggtgtcccct cagaagacag ggatgatgtt gtctcaagag
     4801 gaccccagaa ctgtccaggg agctgatgag aagcaagaac tgaggttggc acaagggctt
     4861 ggggtagctg agggagagga gggggaaggg aagcagagga tgagagcaga ggaggatact
     4921 gagttttcaa aagcagaagg agatggttgc catgcaccaa aagaggatgc aaccaccaag
     4981 gaagatggga aaatctgcat cggcactgcc caagatggcc agcagttaga ggggactgag
     5041 atcggaaagg aggaaaccct gcaccagagc tttagagatg gagacacttc tgaggctcca
     5101 gcaagacagg gaggccactc ggtggagagt caggaagctt ccagagaagg gcagcccgag
     5161 gtagaaggca gaaatccaga tgaaaaggaa gaaagctctt gggtaagctc agaagagagc
     5221 cagggaaggg tgggttctga aaacaacagc ctagaccaag aggggaggct ccaggaccac
     5281 catcaaaggc caggccccca gagccaccat gcagcacgct cctccagggc aatgtctctg
     5341 gacaactgct cacaggtgtc tcagaagggc tcagacagag actttccaag tggagacctc
     5401 aagtacaaca aagccaagaa cagtggggtc ttgcctgcag agaggaaagt ccccatgatg
     5461 tatccagaga gttcctcttc tgagcaagaa gccccctcca gcccgaggcc tccaaagcag
     5521 gaaaaagggg aagatggacg gtcagcttgt acccaggttg ggggtagggt agatggcttt
     5581 ggccaggatg acttagattt ctagacatca aaccataggg cggtaacaga gctgagataa
     5641 atgtattgcc catatgcctg agagaggctc aggccacggg gatgtacaag gaacaggaac
     5701 aaaaccaaag aattgctgcc tgccctggag atgcaggcct agcatcccag cagctcagga
     5761 gttttaggca ggaggataga aagttctaga cccgccccgg actatggagc aagttcaaaa
     5821 ccgagcttgg acaaattagt gggagagcgt ttcaggctat tagaatagag cccagtggca
     5881 gagtgcttgc ctagcttttg tgtggctctg ggttcaactt tgacagccac aaggatgaaa
     5941 aggacagtgc tgtccctggg atctaaaatt caaggccccc gccctcagtg taaagtgtta
     6001 gctgtgagcc tgcctcattt atcagaggtc agccagttcc tcggtccaca gggcccaaga
     6061 ggttagaagg atctgaaaag acaccttggg gcttttctgt gtgttgactt ctttgtagct
     6121 ccccctcccc gcccctattg atcccctgtt actttcccct tggtctctct gggtacactc
     6181 acctttttga ctttgaggca cttttttgct ggtttggaat atgtggtgac tctgcagatg
     6241 tgcgtacttg gaaaaagaag ataaactcag ggtcattgga taaggtttgt tcttagcccc
     6301 tatgtcctaa gttctacacc ccccccccaa gcacacacaa cagacacaca attcatacta
     6361 tttgttaagg gcaaagtggg aagccggaag gaaaagtgat ctcctgttga ccaaggacca
     6421 gaaacagctt cgtgaagtga ttggatgcaa cgctctccat cgttttctgg atgtttcata
     6481 gagatttttg tataatattt acatactgct tccacaaatg cttaaatata tattccttta
     6541 tctaagaaag cttcaaa
//
