LOCUS       NM_001195676            6895 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus RP1, axonemal microtubule associated (Rp1), mRNA.
ACCESSION   NM_001195676 XM_001061481 XM_002726487
VERSION     NM_001195676.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6895)
  AUTHORS   Dharmat,R., Eblimit,A., Robichaux,M.A., Zhang,Z., Nguyen,T.T.,
            Jung,S.Y., He,F., Jain,A., Li,Y., Qin,J., Overbeek,P., Roepman,R.,
            Mardon,G., Wensel,T.G. and Chen,R.
  TITLE     SPATA7 maintains a novel photoreceptor-specific zone in the distal
            connecting cilium
  JOURNAL   J Cell Biol 217 (8), 2851-2865 (2018)
   PUBMED   29899041
REFERENCE   2  (bases 1 to 6895)
  AUTHORS   Karlstetter,M., Sorusch,N., Caramoy,A., Dannhausen,K.,
            Aslanidis,A., Fauser,S., Boesl,M.R., Nagel-Wolfrum,K., Tamm,E.R.,
            Jagle,H., Stoehr,H., Wolfrum,U. and Langmann,T.
  TITLE     Disruption of the retinitis pigmentosa 28 gene Fam161a in mice
            affects photoreceptor ciliary structure and leads to progressive
            retinal degeneration
  JOURNAL   Hum Mol Genet 23 (19), 5197-5210 (2014)
   PUBMED   24833722
REFERENCE   3  (bases 1 to 6895)
  AUTHORS   Daiger,S.P., Sullivan,L.S. and Bowne,S.J.
  TITLE     Genes and mutations causing retinitis pigmentosa
  JOURNAL   Clin Genet 84 (2), 132-141 (2013)
   PUBMED   23701314
  REMARK    Review article
REFERENCE   4  (bases 1 to 6895)
  AUTHORS   Won,J., Shi,L.Y., Hicks,W., Wang,J., Hurd,R., Naggert,J.K.,
            Chang,B. and Nishina,P.M.
  TITLE     Mouse model resources for vision research
  JOURNAL   J Ophthalmol 2011, 391384 (2011)
   PUBMED   21052544
REFERENCE   5  (bases 1 to 6895)
  AUTHORS   Omori,Y., Chaya,T., Katoh,K., Kajimura,N., Sato,S., Muraoka,K.,
            Ueno,S., Koyasu,T., Kondo,M. and Furukawa,T.
  TITLE     Negative regulation of ciliary length by ciliary male germ
            cell-associated kinase (Mak) is required for retinal photoreceptor
            survival
  JOURNAL   Proc Natl Acad Sci U S A 107 (52), 22671-22676 (2010)
   PUBMED   21148103
REFERENCE   6  (bases 1 to 6895)
  AUTHORS   Liu,Q., Zuo,J. and Pierce,E.A.
  TITLE     The retinitis pigmentosa 1 protein is a photoreceptor
            microtubule-associated protein
  JOURNAL   J Neurosci 24 (29), 6427-6436 (2004)
   PUBMED   15269252
REFERENCE   7  (bases 1 to 6895)
  AUTHORS   Liu,Q., Lyubarsky,A., Skalet,J.H., Pugh,E.N. Jr. and Pierce,E.A.
  TITLE     RP1 is required for the correct stacking of outer segment discs
  JOURNAL   Invest Ophthalmol Vis Sci 44 (10), 4171-4183 (2003)
   PUBMED   14507858
REFERENCE   8  (bases 1 to 6895)
  AUTHORS   Zhao,Y., Hong,D.H., Pawlyk,B., Yue,G., Adamian,M., Grynberg,M.,
            Godzik,A. and Li,T.
  TITLE     The retinitis pigmentosa GTPase regulator (RPGR)- interacting
            protein: subserving RPGR function and participating in disk
            morphogenesis
  JOURNAL   Proc Natl Acad Sci U S A 100 (7), 3965-3970 (2003)
   PUBMED   12651948
REFERENCE   9  (bases 1 to 6895)
  AUTHORS   Liu,Q., Zhou,J., Daiger,S.P., Farber,D.B., Heckenlively,J.R.,
            Smith,J.E., Sullivan,L.S., Zuo,J., Milam,A.H. and Pierce,E.A.
  TITLE     Identification and subcellular localization of the RP1 protein in
            human and mouse photoreceptors
  JOURNAL   Invest Ophthalmol Vis Sci 43 (1), 22-32 (2002)
   PUBMED   11773008
REFERENCE   10 (bases 1 to 6895)
  AUTHORS   Uchio-Yamada,K., Manabe,N., Yamaguchi,M., Akashi,N., Goto,Y.,
            Yamamoto,Y., Ogura,A. and Miyamoto,H.
  TITLE     Localization of extracellular matrix receptors in ICGN mice, a
            strain of mice with hereditary nephrotic syndrome
  JOURNAL   J Vet Med Sci 63 (11), 1171-1178 (2001)
   PUBMED   11767049
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from JAXUCZ010000005.1.
            
            On Jan 6, 2023 this sequence version replaced NM_001195676.1.
            
            Summary: This gene encodes a member of the doublecortin family. The
            protein encoded by this gene contains two doublecortin domains,
            which bind microtubules and regulate microtubule polymerization.
            The encoded protein is a photoreceptor microtubule-associated
            protein and is required for correct stacking of outer segment disc.
            This protein and the RP1L1 protein, another retinal-specific
            protein, play essential and synergistic roles in affecting
            photosensitivity and outer segment morphogenesis of rod
            photoreceptors. Because of its response to in vivo retinal oxygen
            levels, this protein was initially named ORP1 (oxygen-regulated
            protein-1). This protein was subsequently designated RP1 (retinitis
            pigmentosa 1) when it was found that mutations in this gene cause
            autosomal dominant retinitis pigmentosa. Mutations in this gene
            also cause autosomal recessive retinitis pigmentosa. [provided by
            RefSeq, Sep 2010].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            CDS exon combination :: SRR26360186.2677648.1 [ECO:0000331]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on computational evidence
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-102               JAXUCZ010000005.1  19957570-19957671
            103-738             JAXUCZ010000005.1  19964582-19965217
            739-910             JAXUCZ010000005.1  19965960-19966131
            911-6895            JAXUCZ010000005.1  19967804-19973788
FEATURES             Location/Qualifiers
     source          1..6895
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q12"
     gene            1..6895
                     /gene="Rp1"
                     /gene_synonym="RGD1560182; Rp1h"
                     /note="RP1, axonemal microtubule associated"
                     /db_xref="GeneID:681377"
                     /db_xref="RGD:1596713"
     exon            1..102
                     /gene="Rp1"
                     /gene_synonym="RGD1560182; Rp1h"
                     /inference="alignment:Splign:2.1.0"
     exon            103..738
                     /gene="Rp1"
                     /gene_synonym="RGD1560182; Rp1h"
                     /inference="alignment:Splign:2.1.0"
     CDS             115..6492
                     /gene="Rp1"
                     /gene_synonym="RGD1560182; Rp1h"
                     /note="retinitis pigmentosa 1 homolog; retinitis
                     pigmentosa 1 (autosomal dominant); rCG30348-like;
                     lipoxygenase homology domain-containing protein 1"
                     /codon_start=1
                     /product="oxygen-regulated protein 1"
                     /protein_id="NP_001182605.1"
                     /db_xref="GeneID:681377"
                     /db_xref="RGD:1596713"
                     /translation="MSETPSTSFSMIRLTSSEGQVPSRHSNVTHPTVAKRISFYKSGD
                     PQFGGVRVVVNPRSFKTFDALLDNLSRKVPLPFGVRNISTPRGRHSITKLEELEDGES
                     YVCSHNKKVLPVDLDKARRRPRPWLSSRSISTHVKLRSATATMPTTAPGLFRAPRRLV
                     VFRNGDPKTRRVVLLSRRITQSFEAFLQYLTQVMQYPVAKLYATDGRKVPSLQAVILS
                     SGAVVAAGREPFKPGNYDIQKYLLPVKLPGISHRVHRKGKAKIEKRKMSTHSVPRPQT
                     DSLASEKTYDCFSDFSVAPENYLALETHDSQTLSTYPSEDGVEKSIVFNQDGTMTVVM
                     KVRFKIKEETVKWTTTVNRADLSNDDEKSKISSYPGKTEDRSSSLKLVVPCSLSEDIT
                     DTTQQGSLTEEENTQMTEQQALSSSSAGWENASMEVGIQGSQKQVKHFYRPPTPGPRR
                     MRQKKSVIGTVTVVSETEVQEKQFSYREEREVGEKSKYHMFTHSCSKMSSVSNKLVQI
                     SSDDERESALERTKESGPLKSHAINAGAIEITSQRVLKMCHNNALASTVPENSVVEEG
                     TDDSAISGKATIKHFRTCGNANDSFSSTTADTTLTSGNNCPNVRTISEVPSVGSPVLT
                     TGLVNEFAHCGLTEHPGNGRQISSPFASKKKKKSQQRMITSKDKKKVIETKGIPNKVG
                     KIHRAGTIAQVVLLQDSGGLDKEGRVREEELDTSPMVIESHDIFPKGNSKFSKNFHKN
                     KLNTVQNPKTQKLLAKRKSRPLKIKSIGELRKQETGQEDKVFLHSESKLCESNLEKQS
                     LLHVFSSLEEDQKALHRSQSQVETVTENWKGMTKKSLVPKVNDLHVTVRNQRKQKGVK
                     LKSGATVSEQHIATRADPLASLKKPDLTEGIPHHSVKSYIQRWLQNINPYPDFEHRKS
                     APLGQDRSNVVNYNSNGFPENNLPTTSSKGKSFLMESNKRKTKNANWKGNKNQETSKS
                     LVVKDNGEQPNKHSCESQDESLYDSYLGPLHDNCTLSQTSINDPCTKSHLSTEKSRPE
                     VKLVYQEMNFSTKRQTLEVAIQVDTMGENVPKDLLALLLQHLEAFIPNNQKHQNGISQ
                     LPGSLAEVVFPSAIYNSSTNLLLAWLLVLNLKRNMNSFCQSDAPKTTSRSSETAALLD
                     VLKHVAITEEADDLKAAVANLVESTKTCSGPSGREQDTAPANCIAASLHSVDKCKENK
                     STQKSLLDEGYSVRGDCGPELCVLEMVSKSNNTPSEGHTVSMTYPPKGVNNQNDALFT
                     SNDSSTMSQRSTHNASFLGEACLLTDSLCSHKACAQKDNIYEAACLSDETHIPIRDCK
                     TIEFVNSKENKCTDNLELTEEIKTVDKVPKDLNILADSIDKNESDISTSSQNVNKLSS
                     QGIFLSKTHLDSDKDYSPLEEFQNCPPKKIVNKKKSVSSDKEDSRTSEEPRSITNSVT
                     SSERNATSELESFEESESQDTGIFNMKVRTEEKAAKESMQKESEARMSLELINISGRN
                     IIEQGRRNTAFLETTGRGQVTPPSLVFCYDSNKNTEKEMSVGETKMRVKKIVDSMENE
                     SYTDSSLNCNKQHRSPGTLDWSDYGSDSESRYPCKALSYEHSDDTGQEREYPRGIVRR
                     AIEKLYGKAEIIKPPFFHGSIHKSQVCPYNPVEVPCVKKTHFYESECQSLVSSEQVSR
                     SSLMLQEFQEERQSEVDANGMGDSFGDSSIEKVTKPSEHGRVFMEKEKGKLIDNGKWL
                     LRENHLWRVSLDNPGMYGNADTTSVDTLMDKNSIEVPYSHFGELAPGPTMAELSSSEI
                     EEMTQPLEVKCNYFNFPHGSDSEPFGEDFLDAQNTNCPKEKIPNHHKEEKRNSPSERT
                     CTPVTQTFASAGNKVHPVCSDVIKTQPLPGSSITHGALQEGDSLDKLYALCGQHCPIL
                     TVIIQPVNEEDRGFAYRKDSDIENSLGFQLWMEIYPFLLQSKKNMFTSESRKVNVGKQ
                     FTDNAIGNLCDRLYFKNMIDLVDKRANSLREEVNLNKVQLYLKKRFSDLLPSSSLVVW
                     DMNSVSLTPSNWTDNFKSVDENNFINRFQNSRKNPNQVVREENSCQFHWELFGQVYLL
                     DICQVEKSLHIKTRSKLEIYYILGGEVLFIWEEENQLNIIDIESPNDQNDL"
     exon            739..910
                     /gene="Rp1"
                     /gene_synonym="RGD1560182; Rp1h"
                     /inference="alignment:Splign:2.1.0"
     exon            911..6895
                     /gene="Rp1"
                     /gene_synonym="RGD1560182; Rp1h"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agacatttgt ttacatgaaa caagcaggtt acatatccag tgatgtttat acaaaccaca
       61 aactatttac tcttttcttc ataaggaaag gttcaagttc tggtctcatc taaaatgagt
      121 gagacacctt ctactagttt ctccatgatt cgtctgactt cttctgaagg tcaagttcct
      181 tctcgccatt caaatgtcac tcatcccaca gtggctaaac gcatcagttt ctataagagc
      241 ggagatcccc agtttggtgg tgttagggtg gtggtcaacc ctcgttcctt taagactttt
      301 gatgccctgc tagacaattt atccaggaaa gtgcccttgc cctttggggt gaggaatatc
      361 agcacgcccc gtggacggca cagcatcacc aagctagagg agctagagga cggcgagtct
      421 tatgtatgct cccacaataa gaaggtgctt ccggttgacc tggacaaggc ccgcaggcgc
      481 cctcggccct ggctcagtag tcgctctata agcacacatg tgaagctccg ctctgctact
      541 gccactatgc ccaccaccgc tcctggcttg tttcgtgccc caaggaggct tgtggtcttt
      601 cggaacggtg acccaaagac caggcgtgtg gtccttctta gccggaggat cactcagagc
      661 ttcgaagcct ttctacagta cctgacacag gtcatgcagt atcctgtggc aaagctgtat
      721 gccacagacg gaagaaaagt tcctagtctc caagcagtga tactgagctc tggagctgtg
      781 gtggcagccg gaagggagcc attcaaacca ggaaattacg acatccaaaa atacttgctt
      841 cctgtcaagt taccaggaat ctctcatcgc gtgcaccgga agggaaaagc caagatagaa
      901 aaaagaaaga tgagcacaca ttcagtccca agaccccaga ctgattccct ggcctcagag
      961 aaaacatatg attgcttttc agacttttct gtagcccctg agaattacct ggccttagag
     1021 acacatgatt ctcagactct atcaacatat ccttctgaag atggtgttga gaaatcgata
     1081 gtttttaatc aagatggtac tatgacggtc gtgatgaaag ttcgattcaa gataaaagaa
     1141 gaaactgtta agtggacaac cactgtcaat agagctgatc tttctaatga tgatgaaaag
     1201 agtaagataa gtagctatcc tggtaaaaca gaagatcgat cgtctagttt aaagcttgtg
     1261 gtgccatgct cattgtctga agacatcaca gacaccactc agcagggcag tttgacagag
     1321 gaagaaaata ctcaaatgac agaacagcag gctctgtcaa gtagctctgc tggctgggag
     1381 aatgcctcca tggaggtagg cattcaggga agccagaaac aagtgaaaca cttttataga
     1441 cccccaaccc ctggaccaag gagaatgaga caaaagaaat ctgtgatagg gactgtcacc
     1501 gtagtatctg aaacagaggt tcaagaaaag cagttttctt atagggaaga aagagaggtt
     1561 ggagaaaaat ccaagtacca catgtttaca cattcttgca gcaaaatgtc ctcagtatct
     1621 aataaactcg ttcagatcag tagcgatgat gagagggagt cagcattaga aagaacaaag
     1681 gaaagtggac cgctcaagtc acatgccata aatgctggtg ctatagaaat tacaagtcag
     1741 agggtcttaa agatgtgcca taacaatgct ttagcgtcaa ctgtaccaga gaactcagtt
     1801 gtggaagaag gcacagatga cagtgccata tcaggcaaag ccactatcaa gcacttcaga
     1861 acttgtggta atgccaatga cagcttcagt tctactacag cagatacaac tcttacctca
     1921 ggtaacaact gtccaaatgt caggactatt tctgaggttc cttctgtagg atctcctgtg
     1981 ctcaccacag gacttgttaa tgaatttgct cattgtggtt taacagaaca tccaggaaat
     2041 ggaaggcaga tttcatcccc ttttgccagc aaaaaaaaga agaaatctca gcagcgaatg
     2101 ataacttcca aggataagaa aaaagtgatt gaaaccaaag gaatccctaa caaagttggg
     2161 aaaatacaca gagcaggaac aattgcacag gtggtactat tgcaagattc gggtggtctg
     2221 gataaagaag ggagagttcg tgaggaggaa cttgacacaa gtcctatggt aattgaatca
     2281 catgatattt tccccaaagg taattccaaa ttttccaaga atttccataa aaacaaatta
     2341 aatactgttc aaaatcctaa gactcaaaaa cttttagcta aaagaaaatc aagaccacta
     2401 aagattaaaa gcataggtga actcagaaaa caagagactg gtcaagaaga taaagtattt
     2461 ctccatagcg aatctaaact ttgtgaaagt aatttggaaa aacaaagttt acttcatgtg
     2521 tttagtagtc ttgaggaaga ccagaaagct ttgcatagat cacagtcaca agtggagaca
     2581 gtaactgaaa attggaaagg aatgacaaaa aagagtttag tcccaaaagt taatgatcta
     2641 cacgtaactg taagaaacca gagaaaacaa aagggagtta aattaaagtc aggtgctaca
     2701 gtaagtgaac agcatattgc aaccagggcg gatcccttag catctttgaa aaaacctgat
     2761 ttaaccgagg gtattcccca tcactcagtt aagagctata tacagcgatg gttgcagaac
     2821 ataaatccat atccagattt tgagcacaga aagtcagctc cactaggcca agatagaagt
     2881 aatgtggtaa attataacag taatggtttt ccggaaaata atctgcctac aacttcttca
     2941 aaaggaaaga gttttttaat ggaaagtaat aagcgcaaaa ctaaaaatgc caattggaaa
     3001 ggcaataaaa atcaagagac aagtaaatct cttgttgtta aagataatgg tgaacagcct
     3061 aataaacatt cctgtgagag ccaagatgag tctctgtatg attcttactt gggtcctttg
     3121 catgacaatt gtactttgtc acagaccagt ataaacgatc cttgtactaa aagtcattta
     3181 tctactgaaa agtcaagacc agaagtgaag cttgtttacc aagaaatgaa cttttccaca
     3241 aaaaggcaaa ctcttgaggt tgccattcag gtagacacta tgggagagaa tgttccaaaa
     3301 gacttactag ctctgttgct ccagcacctg gaagctttta ttcctaataa tcagaagcat
     3361 caaaatggaa tttctcaact accaggttca ttagcagagg ttgtcttccc ttctgcaata
     3421 tataattcat ccacaaatct ccttctggct tggcttttgg tactaaacct aaagagaaat
     3481 atgaatagct tctgtcaaag cgatgctcct aagacgacca gcagatcttc agaaacggct
     3541 gcactgttgg atgttctgaa gcacgtcgcc atcacagagg aagccgatga cttgaaggcc
     3601 gctgttgcca acttagtgga atcaaccaaa acttgcagtg gacccagcgg gagagaacaa
     3661 gatacggcac cagcaaattg tatagcagcc agccttcaca gtgtggacaa gtgtaaggaa
     3721 aacaagagta cccagaagag cctattggat gaaggctact ctgtcagggg ggactgtggc
     3781 cccgagctct gtgttttaga aatggttagc aagtcaaaca acactccaag tgaggggcat
     3841 actgtaagca tgacttatcc tccaaaaggg gtaaataacc aaaatgatgc ccttttcact
     3901 agtaatgata gttctactat gagccagcgt tccacacaca atgcttcttt cctaggagag
     3961 gcctgtttac ttacagatag tttgtgttcc cataaggctt gtgcccagaa ggacaacatc
     4021 tatgaggcag cttgcttgag tgatgagact cacattccca tcagagactg caaaacaatt
     4081 gagttcgtga attcaaaaga aaacaaatgc actgacaatc tggaattaac tgaagaaatc
     4141 aaaactgttg acaaagttcc aaaagaccta aatattttgg cagattctat agataaaaat
     4201 gaatctgata tatcaacttc atcccaaaat gtcaataagt taagttccca aggtattttc
     4261 ctaagcaaaa ctcatctaga ttctgacaag gactatagtc ctctagaaga atttcaaaat
     4321 tgcccaccta agaaaattgt gaataaaaag aaatctgttt cttctgataa ggaagattca
     4381 aggacttctg aagaaccaag gtcaataacc aatagtgtga catcaagtga aagaaatgcc
     4441 acttcagaat tagaatcttt tgaagaatca gaaagtcaag acacaggtat cttcaatatg
     4501 aaggtaagga ctgaagaaaa agctgccaag gagtcaatgc aaaaagaatc agaagctagg
     4561 atgagtttgg aattgataaa catatcaggg aggaatatta tagaacaggg aagaagaaat
     4621 actgcatttc tggagacaac aggtaggggg caggtgacac caccatcttt agttttttgc
     4681 tatgattcta ataaaaacac tgaaaaagag atgagtgtag gagaaactaa gatgagagtt
     4741 aagaagatag tagacagcat ggaaaatgaa agttacacag actcttcact taattgtaac
     4801 aaacagcaca gaagtccagg gaccttagat tggtcagatt atggatcaga cagtgagagc
     4861 cgatatcctt gtaaagcatt gagctatgag cacagtgatg acaccggcca agagagagag
     4921 taccctagag gaattgtgag aagggcaata gaaaagcttt atggcaaagc agagattatc
     4981 aaaccaccat ttttccatgg gtctatacac aaatctcaag tttgtcctta taatcctgtg
     5041 gaagttccgt gtgttaagaa aacacatttt tatgagtctg aatgtcagtc actggtctct
     5101 tctgaacagg tatctagaag ttcactcatg ttgcaggaat tccaggagga aagacaatct
     5161 gaggttgatg ccaatggcat gggagacagt tttggggaca gcagcataga aaaggttaca
     5221 aaaccaagtg agcatggcag ggtctttatg gaaaaagaga agggaaaact gattgacaat
     5281 ggcaaatggc tcctgagaga aaatcatttg tggagggtgt cactggacaa tcctggcatg
     5341 tatggcaatg cagacaccac atcagtggat acactaatgg ataagaatag cattgaggtg
     5401 ccatattcac atttcggaga gttggctcct ggtccaacaa tggctgaatt gtcctcttca
     5461 gaaatagagg aaatgactca accccttgaa gtgaaatgca attattttaa ctttcctcat
     5521 ggtagtgact ctgagccttt tggtgaagat tttctagatg cacagaatac aaactgcccc
     5581 aaagagaaaa tacccaacca tcacaaagag gagaagcgta attctccatc tgaaagaaca
     5641 tgtacgcctg ttactcaaac ctttgcttct gctggtaata aagtccaccc tgtctgcagt
     5701 gatgttatta aaactcagcc attacctgga agtagtataa ctcatggcgc acttcaggaa
     5761 ggcgactctt tggataaact ctatgctctt tgtggtcaac attgtccgat actaactgtt
     5821 attattcaac ctgtaaatga ggaagaccga ggatttgctt atcgaaaaga ttccgatatt
     5881 gaaaattctt tgggttttca gttatggatg gaaatatatc catttctgct acagtcaaag
     5941 aaaaacatgt tcacaagtga gagcaggaaa gtgaatgtgg gcaaacaatt tactgataat
     6001 gccattggta atctgtgtga tcgactttat ttcaaaaaca tgattgactt ggtggataaa
     6061 agagctaact ctttgaggga ggaagttaat ttgaacaaag ttcaattata tttaaagaaa
     6121 aggttttcag atcttttgcc ttcatcgtca ctagtggtgt gggatatgaa ttctgtttca
     6181 ctaaccccca gcaactggac agataacttc aaaagtgttg atgagaacaa cttcattaac
     6241 agattccaga actcaagaaa aaatcccaac caagtagtaa gagaagaaaa cagttgtcaa
     6301 ttccattggg agctgtttgg tcaagtttac ttgttagata tttgccaagt tgagaaatcc
     6361 ttacatatca aaaccagaag taaattagaa atatattaca ttttaggggg tgaagttctt
     6421 ttcatttggg aagaagaaaa tcaattaaat ataatagata ttgaaagccc taatgatcag
     6481 aatgatttat aacttcaata ttagcacaat cattagctgt caattatgtt tttcccataa
     6541 aaaggtacag tacatgggat agactttagg ctagattctc taagaattcc ttgctttttc
     6601 aaaatgagaa taccttggaa aacatattct tggataaaat aaatttgttt ttttttattg
     6661 ctttgttcct cattttctca gtaattaaag ttttatgtag ttttatttta aacatgcatt
     6721 attttgtata gctatgattt tgtctgatca ggatataaga aatatggcca ggacaagaaa
     6781 tatgtcctta aaatgttgtc aagtgcatat atgatattga atatattagt gaataaatat
     6841 aactttaaac tatttcattt aagtgctgat tgaataaaaa gtattattaa agctc
//
