LOCUS       NM_001106848            1256 bp    mRNA    linear   ROD 23-APR-2023
DEFINITION  Rattus norvegicus ring finger protein 7 (Rnf7), mRNA.
ACCESSION   NM_001106848 XM_001065291 XM_217235
VERSION     NM_001106848.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1256)
  AUTHORS   Lei Y, Jin X, Sun M and Ji Z.
  TITLE     RNF7 Induces Skeletal Muscle Cell Apoptosis and Arrests Cell
            Autophagy via Upregulation of THBS1 and Inactivation of the
            PI3K/Akt Signaling Pathway in a Rat Sepsis Model
  JOURNAL   Infect Immun 91 (4), e0053522 (2023)
   PUBMED   36920202
  REMARK    GeneRIF: RNF7 Induces Skeletal Muscle Cell Apoptosis and Arrests
            Cell Autophagy via Upregulation of THBS1 and Inactivation of the
            PI3K/Akt Signaling Pathway in a Rat Sepsis Model.
REFERENCE   2  (bases 1 to 1256)
  AUTHORS   Simo S and Cooper JA.
  TITLE     Rbx2 regulates neuronal migration through different cullin 5-RING
            ligase adaptors
  JOURNAL   Dev Cell 27 (4), 399-411 (2013)
   PUBMED   24210661
REFERENCE   3  (bases 1 to 1256)
  AUTHORS   Tron AE, Arai T, Duda DM, Kuwabara H, Olszewski JL, Fujiwara Y,
            Bahamon BN, Signoretti S, Schulman BA and DeCaprio JA.
  TITLE     The glomuvenous malformation protein Glomulin binds Rbx1 and
            regulates cullin RING ligase-mediated turnover of Fbw7
  JOURNAL   Mol Cell 46 (1), 67-78 (2012)
   PUBMED   22405651
REFERENCE   4  (bases 1 to 1256)
  AUTHORS   Huang DT, Ayrault O, Hunt HW, Taherbhoy AM, Duda DM, Scott DC, Borg
            LA, Neale G, Murray PJ, Roussel MF and Schulman BA.
  TITLE     E2-RING expansion of the NEDD8 cascade confers specificity to
            cullin modification
  JOURNAL   Mol Cell 33 (4), 483-495 (2009)
   PUBMED   19250909
REFERENCE   5  (bases 1 to 1256)
  AUTHORS   Ohta T, Michel JJ, Schottelius AJ and Xiong Y.
  TITLE     ROC1, a homolog of APC11, represents a family of cullin partners
            with an associated ubiquitin ligase activity
  JOURNAL   Mol Cell 3 (4), 535-541 (1999)
   PUBMED   10230407
REFERENCE   6  (bases 1 to 1256)
  AUTHORS   Duan H, Wang Y, Aviram M, Swaroop M, Loo JA, Bian J, Tian Y,
            Mueller T, Bisgaier CL and Sun Y.
  TITLE     SAG, a novel zinc RING finger protein that protects cells from
            apoptosis induced by redox agents
  JOURNAL   Mol Cell Biol 19 (4), 3145-3155 (1999)
   PUBMED   10082581
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473954.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_217235.4, XM_001065291.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB808580.1, CF108145.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132297, SAMEA5760383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1256
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q31"
     gene            1..1256
                     /gene="Rnf7"
                     /note="ring finger protein 7"
                     /db_xref="GeneID:300948"
                     /db_xref="RGD:1311048"
     exon            1..218
                     /gene="Rnf7"
                     /inference="alignment:Splign:2.1.0"
     CDS             44..385
                     /gene="Rnf7"
                     /codon_start=1
                     /product="RING-box protein 2"
                     /protein_id="NP_001100318.1"
                     /db_xref="GeneID:300948"
                     /db_xref="RGD:1311048"
                     /translation="MADVEDGEEPCVLSSHSGSAGSKSGGDKMFSLKKWNAVAMWSWD
                     VECDTCAICRVQVMDACLRCQAENKQEDCVVVWGECNHSFHNCCMSLWVKQNNRCPLC
                     QQDWVVQRIGK"
     exon            219..266
                     /gene="Rnf7"
                     /inference="alignment:Splign:2.1.0"
     exon            267..1256
                     /gene="Rnf7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcctccgcgc ccaacgtccg cgtagccgtt ctgcgccgcc gccatggccg acgtggagga
       61 cggcgaggaa ccctgcgtcc tttcctcgca ttctgggagc gcaggctcca agtcgggagg
      121 cgacaagatg ttctccctca agaagtggaa cgcggtagcc atgtggagct gggacgttga
      181 gtgcgatacc tgcgccatct gcagggtcca ggtgatggat gcctgtctta gatgtcaagc
      241 tgaaaacaaa caagaggact gtgttgtggt ctggggagaa tgtaaccact ccttccacaa
      301 ctgctgcatg tccctgtggg tgaagcagaa caaccgctgc cctctgtgcc agcaggactg
      361 ggtggtccaa agaatcggca agtgagagcc ggcagaggct ctcctggtgc ggtgggtgac
      421 cctggacaac cttgtcacca agtcactgga cagacttgac actccaggga ttcaccttca
      481 gatagaggga atggtgtgtg gcctctggga ctcatccaag gcatggttta tcattttgtc
      541 tgtttaattt tgggaaattg tctacaatta agataattta ttaaaatagc ctttcctacc
      601 tctgtggtgt gtgtgatatg tactgctttg aacaccagca attgaaggat ctttgttgtt
      661 tatctgtcag tacataaggg ctgggagagc attgcgttca cagaagaaca ttttgtgttt
      721 atgcttggtg gctaaaaaaa taaataaaag aatgttacac taaaaaataa aatgcattga
      781 gaagccaact cctacccttt gctcctaata ccctttgttg ttgggagtga ggcaacccat
      841 ggtatcttct tttctataaa tgagggttaa cttgtactga gtgaagaggg taaatacagt
      901 gtaactgtta agaaaccaga agtcgggctg gggatttagc tcagtggtag agcgcttacc
      961 taggaagcgc aaggccctgg gttcggtccc cagctccgaa aaaaagaacc aaaaaaaaaa
     1021 aaaaaaaaga aaccagaagt caaggaaact actgtttcac tgttcaaccg cttagggtta
     1081 aagaagtatt ttctgtttct gggaaggttg tattgtatgt tttagtcaaa atattagtgg
     1141 gaaaatgctt agcagtatgg caccggagtt cattatgcaa tgctttaata aatgaaatat
     1201 tgtgctttga gttattaaag tttgatctct actcttaaat tcattaaaat aattca
//
