LOCUS       NM_001012004            1466 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus ring finger protein 25 (Rnf25), mRNA.
ACCESSION   NM_001012004 XM_217445
VERSION     NM_001012004.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1466)
  AUTHORS   Ding W, Li C, Hu T, Graves-Deal R, Fotia AB, Weissman AM and Coffey
            RJ.
  TITLE     EGF receptor-independent action of TGF-alpha protects Naked2 from
            AO7-mediated ubiquitylation and proteasomal degradation
  JOURNAL   Proc Natl Acad Sci U S A 105 (36), 13433-13438 (2008)
   PUBMED   18757723
REFERENCE   2  (bases 1 to 1466)
  AUTHORS   Shultz MA, Zhang L, Gu YZ, Baker GL, Fannuchi MV, Padua AM, Gurske
            WA, Morin D, Penn SG, Jovanovich SB, Plopper CG and Buckpitt AR.
  TITLE     Gene expression analysis in response to lung toxicants: I.
            Sequencing and microarray development
  JOURNAL   Am J Respir Cell Mol Biol 30 (3), 296-310 (2004)
   PUBMED   12947022
REFERENCE   3  (bases 1 to 1466)
  AUTHORS   Asamitsu K, Tetsuka T, Kanazawa S and Okamoto T.
  TITLE     RING finger protein AO7 supports NF-kappaB-mediated transcription
            by interacting with the transactivation domain of the p65 subunit
  JOURNAL   J Biol Chem 278 (29), 26879-26887 (2003)
   PUBMED   12748188
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CF114855.1, CB691642.1, CB775437.1, BM382839.1 and CK845002.1.
            
            On Apr 6, 2007 this sequence version replaced NM_001012004.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-566               CF114855.1         11-576
            567-706             CB691642.1         236-375
            707-1018            CB775437.1         80-391
            1019-1445           BM382839.1         18-444              c
            1446-1466           CK845002.1         1-21                c
FEATURES             Location/Qualifiers
     source          1..1466
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q33"
     gene            1..1466
                     /gene="Rnf25"
                     /note="ring finger protein 25"
                     /db_xref="GeneID:301515"
                     /db_xref="RGD:1311557"
     exon            1..49
                     /gene="Rnf25"
                     /inference="alignment:Splign:2.1.0"
     CDS             9..1373
                     /gene="Rnf25"
                     /EC_number="2.3.2.27"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase RNF25"
                     /protein_id="NP_001012004.2"
                     /db_xref="GeneID:301515"
                     /db_xref="RGD:1311557"
                     /translation="MAASASTAAGEEDWVLPSEVEVLESIYLDELQVMKGNGRSPWEI
                     FITLHPATAEVQDSQFVCFTLVLQVPVQYPHEVPQISIRNPRGLSDEQIHKISQALGH
                     VAKEGLGTAMLYELIEKGKEILTDNNIPHGQCVICLYGFQEKEAFTKTPCYHYFHCHC
                     LARYIQHMEQELNTQEQEQQHVVTKQKAVGVQCPVCREPLVYDLASLKAAPEPQQPME
                     LYQPSAESLRQQEELKRLYQRQQEKGGIIDLEAERNRYFISLQQPPAALEPESVVDVS
                     RGPQPPNTLSAEQSTSLAAQSTLPTPLPMATQYVYEKTSGAGPNQQRLGETQKSMLDP
                     PRPGRGSWRQYDRRHPKGGECCAPKGTSEIQELPPPEKPLKETVDLKAEPRNKGLTGH
                     PQEKGPGSWQGPSARRTRDCARWERSKNRTPGSSYPHLPRGQGAYRSGTRREPLGLES
                     EEGS"
     exon            50..124
                     /gene="Rnf25"
                     /inference="alignment:Splign:2.1.0"
     exon            125..224
                     /gene="Rnf25"
                     /inference="alignment:Splign:2.1.0"
     exon            225..292
                     /gene="Rnf25"
                     /inference="alignment:Splign:2.1.0"
     exon            293..362
                     /gene="Rnf25"
                     /inference="alignment:Splign:2.1.0"
     exon            363..434
                     /gene="Rnf25"
                     /inference="alignment:Splign:2.1.0"
     exon            435..566
                     /gene="Rnf25"
                     /inference="alignment:Splign:2.1.0"
     exon            567..659
                     /gene="Rnf25"
                     /inference="alignment:Splign:2.1.0"
     exon            660..794
                     /gene="Rnf25"
                     /inference="alignment:Splign:2.1.0"
     exon            795..1449
                     /gene="Rnf25"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagaagacat ggcggcgtct gcgtctacag ctgccgggga agaggactgg gtccttccct
       61 ctgaagttga agtattagaa tctatctatc tggacgaact acaggtgatg aaagggaacg
      121 gcagatcacc atgggagatc ttcatcactc tgcaccctgc caccgcagag gtccaggatt
      181 cgcagtttgt ctgctttact ctggttcttc aggtccccgt gcagtatccc cacgaggtgc
      241 cccagatctc catccgtaac ccccgaggac tttcagatga gcagatccac aagatctcac
      301 aggccctggg ccatgtggcc aaggagggac taggcactgc catgctctat gaactcatcg
      361 agaaggggaa ggagattctc acagataaca acattcccca tggacagtgt gtcatctgcc
      421 tctatggttt ccaggaaaag gaggccttta ccaagacacc gtgttatcac tactttcact
      481 gccactgcct tgccaggtac atccaacaca tggaacaaga gctgaataca caggaacagg
      541 agcaacagca tgttgtcacc aagcagaagg cagtcggtgt gcagtgtcct gtgtgcaggg
      601 agccccttgt gtatgatctt gcctcgctga aagcagcccc tgaaccccaa caacccatgg
      661 agttatacca acccagtgca gagagcttgc gccaacagga agaactcaaa cggctgtatc
      721 agaggcaaca ggaaaagggt ggcatcattg acctggaggc tgaacggaac cgatacttca
      781 ttagccttca gcagcctcct gctgctcttg aacctgagtc agtagtagat gtctcaagag
      841 gaccccaacc acctaatacc ctttctgcag aacaatctac ttccctagct gcccaatcaa
      901 ctctgccaac tcctttaccc atggctaccc agtatgttta tgagaagact tcgggggctg
      961 ggccaaatca acagaggctg ggtgagaccc agaaatccat gctagatcct ccacgacctg
     1021 gtcgtggctc ctggcgacag tatgatcgga ggcacccaaa aggcggggag tgctgcgccc
     1081 caaaaggtac cagtgaaatc caagaactgc cacctcctga gaagcctctc aaggagactg
     1141 tggacttaaa ggcagaaccc cgtaacaaag gcctcacagg tcatcctcag gagaagggac
     1201 ctggtagctg gcagggcccc tcagctcgca ggactcggga ctgtgctcgc tgggaacgct
     1261 ccaaaaaccg tacacctggt tcttcctatc cccatctacc tcggggccag ggagcatacc
     1321 ggtctggtac tcgcagggag cccctgggct tggaatctga ggaaggttcc tagcagtact
     1381 gttgggggac agggaactgg ggtgggaggg aggcaataaa gagatttgac ctttgcttaa
     1441 cagcagctaa aaaaaaaaaa aaaaaa
//
