LOCUS       XM_039087541           17559 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus ring finger protein 213 (Rnf213),
            transcript variant X1, mRNA.
ACCESSION   XM_039087541
VERSION     XM_039087541.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051345.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039087541.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17559
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..17559
                     /gene="Rnf213"
                     /note="ring finger protein 213; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 47
                     ESTs, 2 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 43 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:303735"
                     /db_xref="RGD:1308168"
     CDS             270..15875
                     /gene="Rnf213"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase RNF213 isoform X1"
                     /protein_id="XP_038943469.1"
                     /db_xref="GeneID:303735"
                     /db_xref="RGD:1308168"
                     /translation="MGCPQCGHVSSEKAAKFCSQCGQKLSPAATEQDLKNNNALVEAS
                     TTEGKTEPGEVLREEVVLLSSTDSGKELQTEQGEVLREEVVLLSSTDSGKELQNPEES
                     ESDASWTTHVEVDPEVFVDAAEDTAGGPEGAQCPPSKRKKEETAGCEVVDTEQSKKEK
                     RRRRRQGTISSSEAASMSSGLWSLDLPSGPGSHNSALPQNQAQQGGTANQPGHSLDTV
                     KMPVEKDGSACVEGSGSSLRGPVAEGPEDAQRNPAASDYVEVKDLKTSNPSVDKGPKM
                     TDASQKASLPESKGEQPGHGEKVPPIDTAANPVKRARKETRDDVQKQKPSPVSLATSK
                     DRDQKAELESKLATPVRKSDESRNTQPEDQKKPGGDRNYAAAAKNKNQQAAALEATKS
                     THDPGDRVTVCFHAIVSRDFGFNPDKHRAYVRGGEGLGQKGWTDACEMYYTQDLHDLG
                     SLIEGKMDIPRQSLDKPIPYKYVIHHGSSSKDSVEYEFIYEQPQKKGEHVNRCLQVDS
                     TLLSSGDWHQYDDIIWMRSPGLLQQAKNYITDGTRKNLVRGKKQAAVIMLDRIFSVLQ
                     SWSAINLQTFMTQFRQFYSVVRVPMIHDGHARKWSSLQYEEREVRLNLWEHVKKLMMP
                     FLEGKSGESLPADCPVRSKQILGLSILCMVEAADFTVPKKDLDSLCYLLIPSADSPEA
                     LHRDLSPVLSIRQRWHAYLITLCFRCIEVGCDRWLGILPLLHYCMQQSPPRKNSKSQT
                     EDVWAGLEGISFSEFRDKASARSQALQLMQNRMALLHVDEYLFRSWFSLVPLESLSSY
                     LENSEEYLSHMPTRVLDCFQGISYRLRGLGKISKQNIEDVKKVFKILMYLVDMYQDRI
                     FEESLPQIYLTECADLHETVCSITADRQFYQTPALSAELVCAVLQLSPPEHTEEGLVA
                     KSYEDLVRTTFQEALNTTRKWLRTVFKSPMLSRNFAAVQLSYPDEMAVWRRLVGINFP
                     EKYGWKGPLLGDMEGRLKQESPRLQISFFCSSHCCDEGPHDSVARSIEKCVIEAVSSV
                     CQSQTSVLEGLSCQDLQKFGTLLSAVITKSWPVHNGELVSDVDEIFKYLLKWPDVRQL
                     FKLCGTNENITNHITKEGRRLMVTAESVFQKVAGELENGTIVVGQLELILKYKSQFLG
                     IWDINSQRLQFQEKVYDMKGLLDRRKDDLFFLKREKRYVESLLTQLGRVKHFVQVELG
                     NIERIHSQDLSNKKLNEAVIKPPNSSFSNRKTHYYLSPDILEMASKLDSLKDSHVFQD
                     FWHETAELLSNDTLDQDRRELKLSLPDVVDHLYYPCYEKFYKLYMNLRSGEITFADVD
                     VIFRDFKDKYDELNVDLKFMCTLDPQDRKGWISQRVRQIKEYHTLYQAVSSAKVIVQV
                     RRALGVTGDFSVLNPLLNFADDFEDFRNEKLNQISPQFIKAKELLQDISELRHRCLEE
                     LALQTELVHWLHEALKDINELKVFVDLASISAGENDIDVDRVACFHDAVQGYASLLYK
                     LGANTDFNEFMNHLQELWRALDNDQHLPDKLKDSARNLEWLKTVKESHGSVELSSLSL
                     ATAINSRGIYIIQAPKDGQKVSPDTVLHLLLPDDHGYQEAFRKYSTEELKELLNKLML
                     MSGRKDHSSNVEVETFSEVFSNMQRLVHVFINLHCAGNMLFRTWTAKVYCCPGGGISM
                     DFGSKLLNQLTESGDVIQLLGALCRQMEDFLHEWKTVVAQKRATHFYLNLYTAEQLVY
                     LSSELRKPRPSEAALMMLSFIKGKCTVQELIQATSACENKAARHCLQEAMRKLPQQLL
                     SESTLMGKLRVIMTQSLECMSAFLPSCLDLDTLGRCLAHLARLGGSPVERPLPKGLQV
                     GQPNLILCGHSEVLSAALAIYMQDPMQPLPTFDEVLLCTPGTTIEEVELFLRRCLTLD
                     SQEHKVYSLLFADQLSYEVGCQAEELFQSLSTQVHREDYQLVILCDAAREHCYIPSTF
                     SQHKVPLVPQAPLPDIQAYLENHYQVPKQIQSAATVFRDGLCVGIVTSERAGVGKSLY
                     VNTLHKKLKTKLQDETVPLKIIRLTEPHIDENHVLSALLPFLEKNYQKTPVIFHIDVS
                     TSVQTGIPVFLFKLLILQYLMDINGKMWRRNPCHLYVVEIPQAHSVRPKRSSKLNARA
                     PLFKFLDIFPKVTCRPPKEVINMELTPKRSHIEPGMDPAEFCSEAFQRPYQYLRRFHQ
                     GQNLDAFRYEKDSVEGSPEECLQHFLIYCGLTNPSWSELRNFAWFLNCQLKDCEASVF
                     CNSAFTGDTLRGFKNFVVTFMVLMARDFATPTLQTSDQSPGKHSATIDGVAEEDLAPF
                     SLRKRWESEPHPYVFFNGDRMTMTFIGFHLKTNSNGYVDAINPSSGNIIKKDVMTKEL
                     FDGLKLQRVPFNINFDSLPRHEKLERLCLALGIEWPSDPDETYELTTDNMLKILAIEM
                     RFRCGIPVIIMGETGCGKTRLIKFLSDLRRGSIEAETMKLVKVHGGTTPSMIYSRVKD
                     AERTAFFNKAQHNLETILFFDEANTTDAVSCIKEVLCDRTVGGEHLNEDSGLHVIAAC
                     NPYRKHSQEMIHRLESAGLGYRVGAEETADRLGSIPLRQLVYRVHALPPSLIPLVWDF
                     GQLNDSAERLYIQQIVQRLVDSVTVDQRETFVIANVLSASQEFMRKRENECGFVSLRD
                     VERCVKVFQWFHDHSNMLLNKLADFLRECCDSTPAFERDPVLWSLVMAIGVCYHASLE
                     EKAPYRAAIARCLPKPYNSPKVILNEITHVQDLFLRDAPIRSNIARNLALKENVFMMV
                     ICIELKIPLFLVGKPGSSKSLAKIIVADAMQGQAASSDLFRCLKQVHLVSFQCSPHST
                     PQGIISTFKQCARFQQGKDLQQYVSVVVLDEVGLAEDSPKMPLKTLHPLLEDGCIEDD
                     PAPYKQVGFVGISNWALDPAKMNRGIFVSRGSPNEKELIESAEGICSSDRLVQDRIRG
                     YFAPFAKAYETVCQKQDKEFFGLRDYYSLIKMVFAKAKASKKGLSPRDIAHAVLRNFS
                     GKDDIQALSIFTASLPETLYKEEVSTVELIKQNIHPDLQGSSRGLDSADSRYLLVLTR
                     NYVALQILQQTFFEGQQPEIIFGSSFPQDQEYTQICRNINRVKVCMETGKMVVLLNLQ
                     NLYESLYDALNQYYVYLGGQKYVDLGLGTHRVKCRVHTDFRLIVIEEKDVVYKQFPVP
                     LINRLEKHYLDMNTVLQGWQKGIVQELQRWAHEFADVKADQFIARHKYSPADVFIGYH
                     SHACASVVLQAVERQGCRNLTEELYRKVFEEAKFILLDCATPDAVVRLSGSSLGSFAA
                     NRLSQEYYYKQQHNSFVDFLLAHLRMDHHECWAVFTEITTFSRLLTSHDCDVLESELR
                     GLAPKPIVLSLQQFDTEYSFLKDVRSCLRNPARRKILVIQTDFDDGIHSAQLVASAKY
                     SAINEINKTQGTEDFVFVYFVTKLSRMGSGTPYVGFHGGLWRSVHIDDLRRSTVMASD
                     VTKLQNVTISQLFEPVDKPEPEDDPEEEMETESSKSGEVAEEQMEVEEEGSEEMKRAC
                     DLRGCDVLDTTRLVRSCVQGAVGMLRDQSESCARNMRRVTILLDLLNEESTLNASFLR
                     ESKMRLHVLLNKQEENQVRSLKEWVTREAANQDALQEAGTFRHTLWKRVQDVVTPILA
                     SMISHIDRDGNLELLARPGSPAWAQDLWMFIYSDIKFLNIPLALNNTRSNSEMPFILV
                     QSHMNLLKDACNAVPFSWRIRDYLEELWVQAQYITDTEGLSKKFVEIFQKTPLGLYLA
                     QFPTAQQQELLQSYLKDFLLLTMKVSSREELMFLQMALRSCLSELQVASGTPEEGLSL
                     PWVHLAYQHFRTRLQNFSRILTIHPQVLSSLSQAAEKHNLAGCEMTLDAFAAMACAEI
                     LKGDILKPSPRVWLQLVKNLSMPLELVCSEGYLQDSGSMTRAIIQEVRALWNRIFSIA
                     LFVEHVLLGTESQIPELSPLVTKYVSLLDKCLEEDSNLKTYRPFAAVMTTLCNCKDKA
                     SKKFCRFGIQPCSICQGDAQDPVCLPCDHVYCLPCIQTWLAPGQMICPYCKTELPDKF
                     SPTVSQNHRKAIEKHAQFRHMCNSFFVDLVSTMCFKDNIPPQKSVIDTLLSLLFVQKE
                     LLRDASQRHREHTKSLSPFDDVVDKTPVIRSVVLKLLLKYSFHEVKGYIQNYLSQLEN
                     KAFLTEDKTELYLLFINCLEDSVYQKTSAGCRNHERVLREEGHFLRTYSPGLRGSEPV
                     RTASVEYLQEMARVRLCLDLAADFLSELQEGSELAEDKRCFLKHVEQFCTRVNNDWHR
                     VYLVRKLSSQRGMEFVQSFSRQGHPYQWVFPREVLAQQKDHLSQLDRYLVHGDEYKAV
                     RDAMAKAVLDCKTLDVGNALSTCRSPKDQQTAYLLLALYTEVTALYRSRNGSLHPDSK
                     QLEAMNKFINESKILSAPKINRFAKSLVANTLPLLQTRSANGSLRVTVTEMAIHVATI
                     LLCGQDKVLEPLRNLAFYPFKMVNAFLPTMPEDLLVHAKFWEGLTNVRWYTCPNGHPC
                     SVGECGQPMEMSICPDCRVPIGGLNHKPSVGFDVIRNNEDRTQTGHVLGNPQSSGTAE
                     ASDRGQSPVVFILTRLLTHLAMLVGAAQTPQALMNIIKPPVQDPQGFLEQHIQRDLEQ
                     LTKILGKSADETTHVVHLILSSLLKEQHQMTLNFTEVLSTKGCRNNWEKHFGTLLLRE
                     LKHLDKTLPAINARISQDERISSNPVTKIIYGDPATFLPHLPQKSVVHCSKIWSCRTK
                     ITVEYLQHIVEQKNGKETVPLLWHFLQKEAELRLVKFLPEILALQRDLVKQFQNVSEV
                     EFSSIRSFIHSHHSDGLQKLLHDRITVFLSTWNALRRSLETNGEIKLPKDYCRSDLDL
                     DAKFEVILPRRRGLGLCGTALVSYLISLHNKMVYVVQKLSNEDNSYSVDTSEVADLHV
                     ISYDVERDLNPLILSNCQYQVQQGGETSQEFDLEKIQRQISSRFLQGKPRLTLKGIPT
                     LVYRRDWNYEHLFMDIKNKMTQNPLPNSAINAISGQLQSYSDACEALSIVEVTLGFLS
                     TAGGDPSMELNVYIQEVLQMCDQTSQVLKALNRCQLRHIIALWQFLSAHKSERRLRLK
                     KELFQEVDVKYKEDLSPRHARLLSTFLNEAGLDSFLLELHEMIVLKLRGAQAESSFNP
                     SWSLKDTLVSYMETKDSDVLTEVESQFPDEILMSSCVSVWKTAATRKWDRQSR"
ORIGIN      
        1 gacattccga gtgctgtggg cgcgcagcgg ctgtagtcgc ctctggacaa gcgtgctagg
       61 cccgcgccac caggcgggga attccggtca ggctgtgcgc caaggaggcg gagggcggcg
      121 cccggccccg tgaccccgca gcgaggcgcg cgattccgcg cgggcgcatg ggcactgcag
      181 ggtttctccg tggagctctg gctgtcctgg aactcacttt ggaactcaga tccacctgct
      241 gctgggatta aagggctgtg gatgacagca tggggtgtcc tcagtgcggg catgtctcct
      301 cagagaaggc agccaagttc tgtagccagt gtggacagaa attgtctcct gcagccaccg
      361 agcaagatct caagaacaac aatgccttgg tggaggcatc aaccacggag ggaaagacgg
      421 agccgggtga agtgctgaga gaagaggtgg tcctactctc ctccacagac tccggaaagg
      481 aactgcaaac ggagcagggt gaagtgctga gagaagaggt ggtcctactc tcctccacag
      541 actccggaaa ggaactgcaa aacccagagg agtcagagtc tgatgcctcc tggaccaccc
      601 acgtggaagt ggacccagag gtttttgtag atgctgcaga ggacacagct ggtggtcccg
      661 aaggtgctca gtgccctcct agcaagagga agaaggagga aacggccggg tgtgaggtcg
      721 tggacactga gcagagtaaa aaggagaaga ggaggaggag gagacagggc accatttctt
      781 cttcagaggc ggcttccatg tcctctggcc tctggagtct ggacctgcct tcaggccctg
      841 gctcccacaa ctcagccttg ccccagaacc aagcccagca gggtggtaca gccaaccaac
      901 ctggccattc cctggacaca gtgaagatgc cagtggagaa ggatggctct gcgtgtgtcg
      961 agggcagcgg cagctctctg cggggtccag ttgcggaagg cccagaagat gctcagagga
     1021 accctgctgc cagtgactac gtagaagtca aggacctcaa aacctctaac ccctcagtgg
     1081 acaagggccc taagatgact gatgcttccc agaaggcctc attacctgag tctaaggggg
     1141 agcaacctgg acatggggag aaagtaccgc caatcgacac tgcagccaat ccggtgaaga
     1201 gagctaggaa agaaacaaga gacgatgtgc agaaacagaa accatcgcct gtgagccttg
     1261 ccacctccaa ggacagagac cagaaagctg aactcgagag caagttggcc acccctgtta
     1321 ggaaaagtga cgaaagcagg aacacccaac cagaagatca gaagaagcca ggaggggaca
     1381 gaaattatgc agcagccgcg aaaaacaaaa accagcaggc tgctgcactg gaggctacaa
     1441 agagcacaca tgatccgggg gacagagtca cggtgtgctt ccatgccatc gtctcccgtg
     1501 actttgggtt caatccggac aagcacagag cgtatgtcag agggggagaa gggcttgggc
     1561 agaaaggctg gactgatgct tgcgagatgt actacactca agacctgcat gaccttggat
     1621 ctctcattga ggggaaaatg gacattccta gacagagcct ggacaaaccc atcccttata
     1681 agtacgtcat tcaccatggc agcagtagca aggatagcgt ggaatatgag ttcatctatg
     1741 aacaacccca gaagaaagga gaacacgtga accgttgtct gcaggttgac tctaccctct
     1801 tgagcagtgg agactggcat cagtacgatg acataatctg gatgagatct cctgggttgc
     1861 tccagcaagc caagaactac atcactgatg gcacaagaaa gaacctggtg agagggaaga
     1921 agcaggctgc tgtgatcatg ctcgaccgca tcttcagtgt tctccagtcc tggagtgcca
     1981 tcaacctgca gaccttcatg acccagttcc ggcagttcta ctctgtggtc cgagtgccca
     2041 tgattcacga tggccatgca aggaaatggt ccagtctgca atatgaggag agagaggtga
     2101 ggttaaacct gtgggagcat gtgaaaaagc tgatgatgcc gttcctggaa ggaaagagtg
     2161 gggagtctct gcctgccgac tgccctgtga ggagtaagca gatattgggc ctgagcatcc
     2221 tttgcatggt ggaagcagct gactttactg tacccaaaaa ggacctggac tcgctgtgct
     2281 atctcctcat tcccagtgct gactcaccag aagccctcca cagggacctg agccctgtcc
     2341 tcagcatacg tcaaagatgg catgcatact tgataaccct gtgcttcagg tgcatagaag
     2401 tggggtgtga tcgctggctg ggcatcttac ccctcctgca ctactgcatg cagcagtctc
     2461 cacccaggaa gaactccaag agccagactg aggacgtgtg ggcaggcctc gaaggaatct
     2521 ccttctccga gtttcgtgac aaagcatccg ccaggagcca ggctctccag ttaatgcaga
     2581 ataggatggc cctgctgcat gtagatgagt accttttccg ctcctggttc agcttggtcc
     2641 ctcttgaaag cttatcttcc tacttggaga actccgaaga atacctgagt cacatgccca
     2701 ctcgggtcct ggactgcttt caagggattt cataccgcct tcgaggacta gggaagatct
     2761 caaaacaaaa catagaggat gtcaagaaag tctttaaaat tctgatgtac cttgtggaca
     2821 tgtatcagga caggatcttt gaggagagcc tgccacagat ctacttgact gagtgtgcag
     2881 acctccatga aactgtctgc agcatcactg ctgacagaca attctaccag actcctgccc
     2941 tgtctgctga gcttgtctgt gcagtgcttc agctcagtcc tccagagcat actgaagagg
     3001 ggctggttgc aaaatcttat gaagacttgg tgaggaccac cttccaggag gccctgaaca
     3061 ccacgagaaa gtggctgcgt accgtgttta aaagccccat gctctctaga aactttgccg
     3121 ccgtccaact ttcctatccc gatgagatgg cggtatggcg acggttggtg gggatcaact
     3181 tccctgagaa gtatggctgg aaggggccac tgctaggaga catggaaggg aggctcaaac
     3241 aggagtcacc ccgtttgcag atctccttct tctgcagcag tcattgttgt gatgagggac
     3301 cccatgacag cgtggcaagg agtatcgaga agtgtgtcat cgaagctgtg agctctgtct
     3361 gccagtctca gaccagtgtc cttgaagggc tctcctgtca agatttgcag aaatttggta
     3421 ccctcttgtc tgctgtgata accaagtcat ggcctgtgca caatggggag ctggtgtctg
     3481 atgtggatga gatcttcaaa tacctgctca agtggccaga tgtgaggcag ctcttcaaac
     3541 tgtgtggaac caatgaaaac atcaccaacc acatcacgaa ggaaggcagg cggctgatgg
     3601 tcactgctga gtctgtgttc cagaaggttg caggggaact tgaaaatggc accattgtgg
     3661 ttggacagct ggagttgatc ctaaagtaca agagtcagtt tcttggtatc tgggacataa
     3721 atagtcagag gctgcagttc caagagaagg tctatgatat gaagggcttg ctggacagga
     3781 gaaaggacga tctgttcttc ctcaagcgag agaagagata cgtggagagc ctcctgacgc
     3841 agcttgggag agtgaaacac ttcgtgcaag tggagcttgg aaacatcgaa aggatccact
     3901 ctcaagacct cagcaataag aaactaaatg aagctgtgat taagcccccc aattcctcat
     3961 tctccaacag gaagacacat tactacctga gccctgatat cctagaaatg gcaagcaagc
     4021 tagactctct gaaagacagc catgtcttcc aggatttctg gcatgagaca gcagagttgc
     4081 tgagtaatga tactctggat caggaccgca gagagttgaa gctttcgctt ccagacgtcg
     4141 tcgaccacct gtactaccct tgttatgaga aattctacaa gctctacatg aatctgagat
     4201 caggagagat cacctttgct gatgttgatg tcatcttcag agactttaaa gataaatatg
     4261 acgaactgaa tgttgatctt aaattcatgt gcactctgga cccccaggac agaaaaggtt
     4321 ggatctcaca gcgtgttagg cagatcaaag aataccatac cctgtatcag gctgtcagct
     4381 ctgccaaggt catcgtgcag gtccgaagag ctttgggcgt gaccggtgac ttcagtgttc
     4441 ttaacccgtt gttaaacttt gcagatgact ttgaggactt tcgtaatgag aaactgaacc
     4501 agatcagccc acagttcatc aaggccaaag agctgctcca agacatcagt gagcttcgcc
     4561 accgctgctt ggaggaactc gccctgcaga cggagcttgt ccactggctg cacgaggctc
     4621 tgaaagatat caatgaactc aaggtgtttg tggacctggc ctccatctct gcgggagaga
     4681 atgacattga tgtggaccgc gtggcctgtt tccacgatgc tgtgcaaggt tacgcttctc
     4741 tcctgtacaa gctgggtgca aacacagatt tcaacgagtt catgaaccat ctgcaggaac
     4801 tctggagggc cctggacaat gaccagcacc tgccagataa gctgaaagac tctgccagga
     4861 acctggagtg gctgaagaca gtgaaggaaa gccatgggtc tgtggagctc tcgtctctgt
     4921 ccctggccac agcaatcaac agcaggggca tctacattat ccaggccccc aaagatggcc
     4981 aaaaggtttc cccagacact gttctccacc tcctcctccc tgatgaccat ggttaccagg
     5041 aggcatttcg caaatactcc acagaggagc taaaggagct tttaaacaag ctgatgctaa
     5101 tgtctggcag gaaagaccac agcagcaatg tagaagtgga gacattctcc gaggtcttca
     5161 gcaacatgca gcggcttgta catgtcttca taaacctgca ctgtgcgggc aacatgctgt
     5221 tcaggacttg gactgctaag gtctactgtt gccccggtgg gggcatctcc atggactttg
     5281 gctcaaagct gctgaaccag ctgacagaga gtggagatgt cattcagctc ctgggagcac
     5341 tctgcaggca gatggaggac ttcctacacg agtggaaaac agtggtcgcc cagaagagag
     5401 ctacacactt ttacctcaac ttgtacacag ctgagcagct ggtctaccta agcagcgagc
     5461 tcaggaagcc cagacctagt gaggctgccc tcatgatgct gtccttcatt aaaggcaaat
     5521 gcactgtcca ggagctcata caagctacca gtgcctgtga aaacaaggct gccagacact
     5581 gcctgcagga ggctatgaga aagctgcctc agcagctact ttctgagtcc accctaatgg
     5641 gcaagcttcg ggttattatg acgcaatccc tagagtgcat gagtgccttc ctgccgagct
     5701 gtctggacct agataccctg ggtagatgcc tggctcatct ggccaggctg ggtggctctc
     5761 ctgtggagcg gccactcccc aaaggcctgc aggttggcca gcctaacctg atcttgtgcg
     5821 gccactctga ggtgttgtca gctgcgctgg ccatatacat gcaggacccc atgcagccct
     5881 tgccgacctt tgatgaggtg ctgctctgca ccccagggac cacaatcgag gaggtggaac
     5941 tattcctgcg acgctgcctc actttggact cccaggagca caaggtctac agcttgctgt
     6001 tcgcagatca gttgagctat gaagtgggct gccaggcaga ggagctcttc cagagcctga
     6061 gcacacaggt gcaccgtgaa gactaccagt tggtgatact ctgcgatgct gcccgggagc
     6121 actgctacat tccctccacc ttcagccagc acaaagtccc cctggtgccc caggccccac
     6181 tgccggacat ccaagcctac ctggagaacc attatcaggt cccgaagcag atccagtcag
     6241 cagcaactgt gttcagagat gggctgtgtg tgggaatcgt gacctctgaa agagctggcg
     6301 ttggaaagtc tctctacgtg aacacgttgc acaaaaaact gaagacgaag ctacaggatg
     6361 agacggtgcc tttaaaaatt attcggttga cagagcctca catagacgag aaccacgtcc
     6421 tgagcgccct cctgccattc ttggagaaga actatcagaa gacgccggtc atattccaca
     6481 tcgatgtgag cacttcggtt cagactggaa ttcccgtctt ccttttcaaa ctcctcattc
     6541 tgcagtacct aatggatata aatgggaaaa tgtggcgtcg gaatccgtgt catttatatg
     6601 ttgttgaaat cccacaagcc cactcagtac ggccaaagag gtcttctaaa ctgaatgcac
     6661 gtgcacccct tttcaaattt cttgatatct tccccaaagt cacctgccgt cctcccaagg
     6721 aggtgataaa catggagctg actcccaaga ggagccacat agaacctggg atggacccag
     6781 cggagttctg cagtgaagct ttccaaagac cttaccagta cttaagacgg ttccatcagg
     6841 ggcagaacct ggacgcattt cggtatgaaa aagactctgt ggaaggctct cctgaggaat
     6901 gcctgcagca cttcctgatt tactgtggcc tgacaaaccc ttcctggtcg gagcttcgga
     6961 actttgcttg gtttctgaac tgtcagctca aagactgtga ggcatctgtc ttctgcaatt
     7021 cagcttttac tggagacaca cttcggggct tcaagaactt cgtggtgacc ttcatggtct
     7081 taatggccag ggattttgcc actccgactc ttcagacttc agaccaaagc ccaggtaagc
     7141 actcggccac cattgacgga gtagctgaag aagacctagc tcccttctct cttcgaaaga
     7201 gatgggagtc agagccccat ccatatgttt tcttcaacgg tgatcgcatg accatgacat
     7261 tcataggttt tcacttgaag accaatagca atggctatgt tgatgccatc aatccctcaa
     7321 gtgggaatat catcaaaaag gacgtcatga ccaaagaact gtttgatggg ctgaagcttc
     7381 agagagtgcc cttcaacatc aactttgata gcttgcccag acatgagaag cttgaaaggc
     7441 tctgcctggc actaggtatc gagtggccta gtgaccccga tgaaacatat gaacttacca
     7501 cggacaatat gcttaagatc ctggccattg aaatgcggtt ccggtgtggg atcccagtta
     7561 tcatcatggg agagacgggc tgtgggaaga ccagactcat caaatttctt agcgacctca
     7621 ggcgtggtag cattgaggca gaaactatga agttggtgaa ggttcatgga gggacaacac
     7681 catccatgat ctactccagg gtcaaggatg ctgagagaac agccttcttc aataaggccc
     7741 aacacaactt ggagaccatc ttgttctttg acgaagccaa cacaacagat gctgtgagct
     7801 gtatcaaaga ggtcttgtgc gaccggacag tgggtggtga gcacctaaat gaggactctg
     7861 gtctgcatgt cattgctgcc tgcaaccctt accggaagca ctcccaggag atgatccacc
     7921 gcctggagtc agcaggtttg ggatatagag tgggtgcaga ggagactgca gacaggctgg
     7981 gctccatccc cctgcggcag ctggtatatc gagtccacgc tctgcctcca agcctcattc
     8041 ctttggtatg ggactttgga caactgaatg actctgcaga aaggctctac atccaacaga
     8101 tcgtacagag actggtggac tctgtcacag tggatcaaag agagactttc gtgattgcca
     8161 acgtgctctc tgcctctcag gagttcatga ggaagagaga gaatgaatgt ggtttcgtca
     8221 gcctccggga tgtggagcgc tgtgtgaaag ttttccagtg gtttcacgac cacagtaaca
     8281 tgctcttaaa caagctggcc gactttctcc gtgaatgctg tgacagcacg cctgcttttg
     8341 agagagatcc tgttctctgg tccctggtga tggccattgg ggtatgctac cacgcctctt
     8401 tagaagagaa agcaccctac cgtgcagcca ttgcccggtg ccttcccaaa ccatacaaca
     8461 gccccaaggt catcctcaat gagatcacgc atgtacagga tctttttctg agggatgcac
     8521 ccataaggag caacatagcc aggaacttgg ctttgaagga gaacgtcttc atgatggtaa
     8581 tctgcattga gcttaagatt ccacttttcc tagtggggaa gcccggcagc tccaaatccc
     8641 tggccaagat tattgtagca gacgccatgc aagggcaggc tgcctcctcg gacctcttcc
     8701 gctgcctgaa acaggtccat ctggtgtcat tccagtgcag cccccattcc accccgcagg
     8761 gcatcatcag cacctttaag cagtgcgctc ggttccagca ggggaaggac ctgcagcagt
     8821 atgtctccgt ggtggtgctg gatgaggtgg ggctggctga agactcaccc aagatgcccc
     8881 tcaagaccct gcaccccctg ctggaagacg ggtgcattga agatgaccct gccccgtaca
     8941 aacaagtcgg cttcgttggc atttccaact gggctctaga ccctgccaag atgaaccgag
     9001 gcatttttgt gtcacgtggc agtcccaatg agaaagagct catagagagc gccgagggga
     9061 tctgctcttc cgacaggctg gttcaggata gaatccgcgg gtattttgca ccctttgcca
     9121 aggcctatga aacagtgtgt cagaagcaag ataaggagtt ctttgggctt cgtgactatt
     9181 acagcctcat caagatggtc tttgccaaag ccaaagcttc taaaaagggg ctctcccccc
     9241 gagacatcgc tcatgctgtc cttcggaact tcagtggtaa agatgatatc caggccctga
     9301 gcatcttcac agccagtctt cccgagaccc tgtacaagga agaagtcagt actgtggagc
     9361 tcatcaagca gaacattcac cctgacctgc agggatccag caggggcctg gacagtgctg
     9421 actcccgtta cttgcttgtg ctgaccagga actatgtggc cctgcagatc ctacagcaga
     9481 cattctttga gggtcagcaa cccgagatca ttttcggctc cagctttccc caggaccagg
     9541 aatacaccca gatctgcagg aacattaacc gggtgaaggt atgcatggag acagggaaga
     9601 tggtagtgtt gctgaacctg cagaatctct atgagagcct gtatgatgct ctcaaccagt
     9661 actatgtcta ccttgggggc cagaagtacg tggaccttgg actaggtacc caccgagtca
     9721 agtgtcgagt ccacactgat ttccgcctca tcgtcatcga ggagaaagat gtggtgtaca
     9781 agcagttccc tgtgcccctc atcaaccgtc tggagaagca ctacctggac atgaacactg
     9841 tgctgcaggg gtggcagaag ggcatcgtgc aggagctgca gcggtgggca cacgagtttg
     9901 cagatgtgaa agcagaccag ttcattgcca gacacaagta cagtcctgca gatgtcttca
     9961 tcggctacca ttcccatgcc tgtgcctctg tggtgctgca ggctgtagag aggcagggct
    10021 gcaggaatct cacagaggag ctgtaccgaa aggtgtttga agaggccaag ttcatcctgc
    10081 tggattgtgc aacaccagac gctgtggtca ggctgagtgg ttcctcttta ggctcattcg
    10141 ctgcaaatcg gctgtcacag gagtattact acaaacagca gcacaactct tttgtagact
    10201 tcctcctggc ccacttgcgc atggaccatc atgaatgctg ggctgtcttc acagagatca
    10261 ccactttctc cagactgctg accagtcatg actgtgatgt cctagagtct gagctgagag
    10321 gactggcccc aaagcctatt gtgctgtcac tacagcagtt tgacactgaa tattcgttcc
    10381 ttaaggatgt ccgctcctgc ttaaggaacc cagccaggcg taagatcctt gtcatccaga
    10441 cagactttga cgatggcatc catagtgcgc agctcgtagc ctctgccaag tattctgcca
    10501 tcaatgaaat caacaaaaca cagggaacag aggacttcgt cttcgtttat tttgtcacaa
    10561 aactgtctcg aatgggaagt ggtacaccat acgtggggtt ccatggaggg ctatggaggt
    10621 ctgtacatat tgatgacctc cgcagatcga cagtcatggc ctcagatgtc accaaactgc
    10681 agaatgtcac catcagccag ctgtttgagc cagtggacaa acctgagcca gaggatgacc
    10741 cagaggagga gatggagaca gagtccagca agtcggggga agtggcagag gaacaaatgg
    10801 aagtggaaga agaaggttcg gaggagatga agagggcctg tgacctgaga ggctgtgatg
    10861 tcctggacac caccagactg gtgcggagct gcgtgcaggg cgccgtgggg atgctcagag
    10921 accagagtga gagctgtgca cgcaacatga ggagagtcac cattcttctt gacctcttaa
    10981 atgaagagag cacactcaat gcttcttttt tgcgggaatc taagatgcgc ctccatgttc
    11041 ttctaaacaa gcaagaagag aaccaggtcc gaagtctaaa ggaatgggtc accagggagg
    11101 ctgccaatca ggatgccctg caggaggcag gcaccttcag gcacaccctt tggaagcggg
    11161 tccaagatgt ggtcaccccc atcctggcaa gcatgatatc tcacatcgac agagatggca
    11221 acctggagct tctggcccgg ccaggttcac cggcctgggc tcaagatctt tggatgttta
    11281 tttacagtga tattaagttc ctgaacatcc ctcttgcgct gaataacaca aggtccaaca
    11341 gtgagatgcc cttcatcctg gtgcagagcc acatgaacct gctcaaggat gcctgcaatg
    11401 ctgtcccctt cagctggaga atcagggact acctggagga gctctgggtg caggctcagt
    11461 atatcacaga cacagaggga ttatcaaaaa agtttgtgga aatcttccag aaaactccct
    11521 tgggcctgta tcttgctcag ttccccacgg cacagcagca ggaactcctg cagagctact
    11581 tgaaggactt cctgctcttg accatgaaag tgtcttcacg ggaggagtta atgtttctgc
    11641 agatggccct gaggtcctgc ctcagtgagc tccaagtggc ttcaggaaca cctgaagagg
    11701 gactctcctt gccctgggtg caccttgcct atcagcactt caggacccgg ctccagaact
    11761 tctccagaat tctgaccatc cacccccagg ttctgagcag cctcagtcaa gcagcagaga
    11821 agcacaactt ggctgggtgt gaaatgacac tcgatgcatt tgcagcaatg gcctgtgctg
    11881 aaatactgaa gggagacatc ctgaagccaa gccccagggt ttggttacag ctcgtaaaga
    11941 atctgtccat gcccctggag cttgtctgtt cagaagggta cttacaagac agtgggagca
    12001 tgaccagagc tatcatccag gaggtcagag ccctgtggaa ccgcatcttc tccattgccc
    12061 tctttgtgga gcacgttctt ctgggcactg agagccagat tcctgagctg agtccactgg
    12121 taaccaagta tgtctcctta ctagacaaat gtcttgaaga ggattctaac ctcaagacct
    12181 acaggccatt tgcggctgta atgaccacac tctgtaactg caaggacaaa gccagcaaga
    12241 agttctgcag gtttggtatc cagccctgtt caatctgcca gggagatgca caggaccctg
    12301 tatgtctgcc ctgtgatcat gtgtattgtc taccttgcat tcaaacctgg ctcgccccag
    12361 gacaaatgat atgcccctac tgcaaaactg agttgccaga caagttctcg ccaactgttt
    12421 cccagaacca caggaaagcc attgagaagc acgcccagtt ccggcatatg tgcaacagct
    12481 tctttgtgga cctggtctct accatgtgct tcaaggataa cattccccct cagaagagtg
    12541 tgattgacac cctgctgtcc ttactcttcg tacaaaagga gctgctgaga gatgcttccc
    12601 aaagacaccg tgaacacaca aagtctctgt ctccatttga tgatgttgtt gacaagactc
    12661 ctgtcatccg ctctgtggtg ttaaaactgc ttcttaagta cagcttccat gaagtaaagg
    12721 gttacatcca gaactacctg agccagttag agaacaaagc cttcctaaca gaagacaaaa
    12781 cagagctgta cctgctcttt atcaactgcc tggaggactc agtatatcag aagacaagtg
    12841 ctggctgcag aaatcatgaa cgggttctca gagaggaagg ccatttcctt aggacatatt
    12901 ccccaggact gcgaggctca gagcctgtcc gcactgcttc agtggagtac ctgcaggaaa
    12961 tggccagagt ccgcctgtgc cttgacttgg ctgctgactt cctctcagag cttcaggaag
    13021 gctcagaact ggctgaagat aagcggtgct tcctgaagca tgttgagcag ttctgcacac
    13081 gtgtcaacaa tgattggcac agggtgtacc tggtgaggaa actctcaagt cagcgtggga
    13141 tggaattcgt gcagagcttc tccaggcagg gccatccata ccaatgggtg tttcccaggg
    13201 aagtccttgc acagcagaag gaccacctaa gtcagctgga ccgataccta gtccatggtg
    13261 atgaatacaa ggctgttcgt gatgcaatgg ccaaagctgt gctcgactgc aagaccctag
    13321 acgttgggaa tgctctgtcg acctgcagaa gccccaaaga ccagcagaca gcctacttat
    13381 tgttggcctt gtacacagaa gtgactgctt tgtaccgttc ccgcaatggc agcctccatc
    13441 cagactcaaa gcaattggag gctatgaaca aattcattaa tgaaagcaag atcctctctg
    13501 ctcctaagat caaccgcttt gcaaaatcgc tagtggctaa tactctgccc ctgctgcaga
    13561 ccaggtctgc taacggcagc ctgcgagtaa cagtgactga aatggccatc catgtggcaa
    13621 ccatactcct ctgtggacaa gacaaagtct tggaacccct gaggaacttg gccttctatc
    13681 ccttcaaaat ggtgaatgct tttcttccaa ctatgcctga agacctgctg gttcatgcca
    13741 agttttggga gggcctgaca aatgtccgct ggtacacttg tcccaacggc catccatgct
    13801 ctgtaggaga gtgtggccag ccaatggaaa tgagcatctg tccggactgt cgtgttccaa
    13861 tcggaggcct caatcacaag ccgagtgtgg gctttgatgt tatcagaaac aatgaggata
    13921 gaacgcagac tggccatgtg ttggggaatc cacagtccag cgggacagca gaagcatctg
    13981 accgagggca gtccccggtg gtctttattc tcacccggct actcactcat ctggctatgc
    14041 ttgtgggcgc cgcccagact cctcaggccc tgatgaatat cattaagcct ccggtccagg
    14101 acccacaagg cttcctagag cagcacatcc agagagacct ggaacagcta accaagatac
    14161 tgggcaaaag tgcagacgag accacccatg tggtgcacct catcctcagc agcctgctca
    14221 aggagcagca ccagatgaca ttgaatttta ctgaagtatt atcaaccaaa ggatgcagaa
    14281 acaactggga gaagcatttt ggaactcttc ttctacgtga actgaagcat cttgacaaaa
    14341 ccttgccagc tataaacgct cgtatcagcc aagatgagcg catcagttcc aaccctgtga
    14401 ccaaaatcat atatggggac ccagcaacct tcctgcccca cttgccccaa aaaagtgtag
    14461 ttcattgctc gaagatctgg agctgcagga cgaagattac agtggagtac ctgcagcaca
    14521 tcgtggaaca gaaaaatggc aaagaaactg tgcctctcct ctggcacttc ctccagaagg
    14581 aagcagaact aaggctggtg aaattcttgc ctgagatctt ggccctgcaa agagacctag
    14641 tcaaacagtt ccagaatgtc tcggaagttg aattcagttc catcagaagc tttatccaca
    14701 gtcaccattc agatgggctg caaaagctgt tacatgatcg aatcactgtc tttctgtcca
    14761 cgtggaatgc actgaggcgg tctctggaga ccaacggtga gatcaagcta ccaaaagatt
    14821 actgccgttc tgacttggat ctggatgcta aatttgaggt catccttcca cggcgacggg
    14881 gcttaggcct ctgtggaact gctttagtca gctacttgat tagcctacac aataaaatgg
    14941 tctacgtggt gcaaaagctc tccaatgaag acaacagcta ctctgtagat acctctgagg
    15001 ttgctgacct gcatgtcatc agttatgatg tggagcggga cctgaatcca ctgatccttt
    15061 ccaactgcca gtaccaagtg cagcaaggtg gggaaacctc acaagagttt gatctagaga
    15121 agatccagcg gcagatcagc agccgcttcc tccagggcaa gcctaggctc accctcaagg
    15181 gaatacccac cctggtgtac agacgggact ggaactatga gcatctcttc atggacatca
    15241 agaacaaaat gacacagaac ccactcccta actcagccat caatgccatc agtggacagc
    15301 tacagtccta tagtgatgcc tgtgaagctc tgtctattgt agaagtcact ctgggtttcc
    15361 tgagcacagc tggtggggat cctagcatgg agttgaatgt gtacatccaa gaagttctac
    15421 agatgtgtga tcagacatct caggtcttaa aggccttaaa tagatgtcag ctgagacaca
    15481 tcattgccct ctggcagttc ctatctgcac ataagtcaga acggcggctt cgactgaaga
    15541 aagagctatt tcaggaagtt gatgtgaaat acaaagagga cctcagtcca cggcacgcaa
    15601 gactcctcag cacattcctg aatgaggcag gcctagacag cttcctcctg gagctccatg
    15661 agatgattgt gctcaaactc aggggtgccc aggctgagag cagcttcaac cccagttgga
    15721 gcctcaagga tactctagta agttacatgg agactaaaga cagtgacgtc cttacagaag
    15781 tggagtccca gttcccagat gaaatactca tgtccagctg cgtctcagtg tggaaaacag
    15841 ctgccacaag aaagtgggac aggcagtcaa ggtagagcag ttcggccttc aaacccagct
    15901 ggaaagaacg gtcttcccca cctgcctcca cagctcccag tatggactgt ggcctttgtg
    15961 tgaaggaaag tgtgggtaca gactggattc aaggccacac gaactgtaca atgcgacagc
    16021 tctttgaaag acaagctgtt tctggaacat gtgcctattc cagaacttaa gtgtgactgt
    16081 taatcagctg cctcctgaac attccagaag aaaggagaac tgcagtaagg ccacacccaa
    16141 tactgatcct cctgaagatt gccaacctct tacctcatat accatggcta ccactttact
    16201 gcacagagag aaaaaactca ggatagtcaa ttttttattc tattacttat gtataaaaga
    16261 atctgtttat tctttcttcc aattccttaa tttctaagta gtgtacacat atctcttggt
    16321 ttgcaagata tatggaaatt gccacactaa cccaaggaaa tccaaggtgc tgataaaaac
    16381 tatgaggcct catgaacaag atctaatgta aacccaccat gagtcactgc caaatactca
    16441 ctgagaacac tggacagaga gtgaaggagg aggagtgcat tggcgagttg gaactagagg
    16501 tgggtgatag agtacttgcc taccatatgt aaagccctgg gttctctccc cagcactgca
    16561 agtgggagac aaacaaacaa taaaacagtc gactgaagcc aaatctcacg tcttgagatt
    16621 cctaatgagg atgtgttagt gtaagctcta atcagaggta tttgggaact gcgtacgtag
    16681 ctcaggctga gcccctgtct agcatctgtg gttcctagca ctgttgaaaa ggaaaggtac
    16741 tggggagtac tgaggagagt tgctgatcgt atagctgtct aataagcagg caatgtgatc
    16801 ttaccttcct tgagcacaca attatctggc cctttgagtc tcggccaagg ctgagaccaa
    16861 accagttaaa gagaaagcag aaaaagaccc tccccacaac cccacactcc ttctgcccat
    16921 ctcactgtaa tcacctttgg ttccctccat ccccctggac taaccctatt cctggcaact
    16981 ctccaccatc cgcagtggtg taagaacaca gtgtttacag gttggaagtt gtttccttca
    17041 cagactcaat aaacttgaac tctaggccca cgtactttga gcatccatgg actcagccct
    17101 atcagcagga ggtgcatctg gaaccatgct gacattgtct tcaagcttgg tgtggggacc
    17161 agaccctggc agtagctcat ttcagctctg cacttagagc agtggtgatc ttttcttcta
    17221 aactatgaga gtacctgtcc tcagatgtct gcatcccagg ttttttgggt acagggctta
    17281 aagaacttgc caacttggcc ttggaatccc tgtgttttga tgaaacagga cagcttagcc
    17341 ccaaacttct tgctgtaagg cccttttggc tttgaactaa gcattttttc tgtcatgaag
    17401 aattttatta agatgtttta ttttgtatgc tatgctttta aagtcatcac tgtctgtgta
    17461 gtagaaccca ccgtgtctgt acaaatgcat ggatctaaca ctggcaaagc acactgcatt
    17521 gtgtttgcca cacccacttt aataaacttg aacatcaca
//
