LOCUS       NM_001399205            2650 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus ring finger protein 19B (Rnf19b), mRNA.
ACCESSION   NM_001399205 XM_008764147
VERSION     NM_001399205.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2650)
  AUTHORS   Kaneko,M., Iwase,I., Yamasaki,Y., Takai,T., Wu,Y., Kanemoto,S.,
            Matsuhisa,K., Asada,R., Okuma,Y., Watanabe,T., Imaizumi,K. and
            Nomura,Y.
  TITLE     Genome-wide identification and gene expression profiling of
            ubiquitin ligases for endoplasmic reticulum protein degradation
  JOURNAL   Sci Rep 6, 30955 (2016)
   PUBMED   27485036
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2650)
  AUTHORS   Hoover,R.G., Gullickson,G. and Kornbluth,J.
  TITLE     Impaired NK cytolytic activity and enhanced tumor growth in NK
            lytic-associated molecule-deficient mice
  JOURNAL   J Immunol 183 (11), 6913-6921 (2009)
   PUBMED   19915045
REFERENCE   3  (bases 1 to 2650)
  AUTHORS   Ebstein,F., Lange,N., Urban,S., Seifert,U., Kruger,E. and
            Kloetzel,P.M.
  TITLE     Maturation of human dendritic cells is accompanied by functional
            remodelling of the ubiquitin-proteasome system
  JOURNAL   Int J Biochem Cell Biol 41 (5), 1205-1215 (2009)
   PUBMED   19028597
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Jan 4, 2022 this sequence version replaced XM_008764147.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR22582416.645105.1,
                                           SRR26643288.23783.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-739               JAXUCZ010000005.1  146690577-146691315
            740-945             JAXUCZ010000005.1  146702535-146702740
            946-1087            JAXUCZ010000005.1  146704441-146704582
            1088-1250           JAXUCZ010000005.1  146706227-146706389
            1251-1365           JAXUCZ010000005.1  146706809-146706923
            1366-1506           JAXUCZ010000005.1  146708719-146708859
            1507-1714           JAXUCZ010000005.1  146709988-146710195
            1715-1846           JAXUCZ010000005.1  146712604-146712735
            1847-2650           JAXUCZ010000005.1  146713591-146714394
FEATURES             Location/Qualifiers
     source          1..2650
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..2650
                     /gene="Rnf19b"
                     /gene_synonym="Ibrdc3"
                     /note="ring finger protein 19B"
                     /db_xref="GeneID:313806"
                     /db_xref="RGD:1305470"
     exon            1..739
                     /gene="Rnf19b"
                     /gene_synonym="Ibrdc3"
                     /inference="alignment:Splign:2.1.0"
     CDS             123..2315
                     /gene="Rnf19b"
                     /gene_synonym="Ibrdc3"
                     /EC_number="2.3.2.27"
                     /note="IBR domain containing 3"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase RNF19B"
                     /protein_id="NP_001386134.1"
                     /db_xref="GeneID:313806"
                     /db_xref="RGD:1305470"
                     /translation="MGSEKDSESPRSTSLHAAAPDPKCRSGGRRRRLTFHSVFSASAR
                     GRRARTKPQAEPPPPAAPPPPAPAPVEAQAPPMEALPSEPAAEAEAEAAAARPEEDEA
                     AEGGGAEEVECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPEC
                     SERLNPHDIRLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCP
                     KLTCEREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPDD
                     IKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPW
                     SRKKKILWQLGTLIGAPVGISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRN
                     LAITGGVTLSVIASPVIAAVSVGIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVK
                     IEFDEDDGPITVADAWRALKNPSIGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETAS
                     FAALSGGTLSGGILSSGKGKYSRLEVQADVQKEIFPKDTASLGAISDSASTRAMAGSI
                     ISSYNPQDRECNNMEIQVDIEAKPSHYQLVSGSSTEDSLHVHAQVAENEEEGNGGGAG
                     GGSGGSEDDPPYKHQSCEQKDCLASKAWDISLAQPESIRSDLESSDTQSDDVPDITSD
                     ECGSPRPHTAACPSTPRVHGAPSPSAHKSLAAPAEGQTVLKPEEYEVE"
     exon            740..945
                     /gene="Rnf19b"
                     /gene_synonym="Ibrdc3"
                     /inference="alignment:Splign:2.1.0"
     exon            946..1087
                     /gene="Rnf19b"
                     /gene_synonym="Ibrdc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1088..1250
                     /gene="Rnf19b"
                     /gene_synonym="Ibrdc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1251..1365
                     /gene="Rnf19b"
                     /gene_synonym="Ibrdc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1366..1506
                     /gene="Rnf19b"
                     /gene_synonym="Ibrdc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1507..1714
                     /gene="Rnf19b"
                     /gene_synonym="Ibrdc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1715..1846
                     /gene="Rnf19b"
                     /gene_synonym="Ibrdc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1847..2650
                     /gene="Rnf19b"
                     /gene_synonym="Ibrdc3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcttctgtct ctgggagggc tgccgaggcg gcggcggcta cggccggggc gccggctggg
       61 gggcgctgag gcgggagcta cggcggcgct gggcgcccct ggctccttag cctctgccgg
      121 ccatgggctc cgagaaggac tccgagtcgc cgcgctccac ctcgctccat gcggccgccc
      181 ccgaccctaa gtgccgcagc ggtggccggc gccggcgcct caccttccac agcgtcttct
      241 ctgcctcggc ccgcggccgc cgcgcccgga ccaagcctca ggccgaaccg ccgcccccgg
      301 ccgcgccgcc gccgcccgcc ccggccccag ttgaagctca ggccccgccg atggaagctc
      361 tgccctcgga gcccgctgcc gaggctgagg cggaggccgc ggctgcccgg cccgaggagg
      421 acgaggcggc ggagggcggc ggcgcggagg aggtggagtg cccgctgtgc ctagtgcgcc
      481 taccgcccga gcgggccccg cgcctcctca gctgcccgca tcgctcgtgc cgggactgcc
      541 tccgccacta cctgcgcctg gagatcagcg agagccgcgt gcccatcagc tgccccgagt
      601 gcagtgagcg gctcaaccca cacgacatcc gtctgctgct ggccgacccg ccgctcatgc
      661 acaagtatga agagttcatg ctgcgccggt acctggcctc ggacccggac tgccgctggt
      721 gtccggcccc tgactgcggc tatgctgtca ttgcctatgg ctgcgccagc tgcccaaagc
      781 tgacctgtga gagggagggc tgccagactg agttctgcta ccactgcaag cagatatggc
      841 atccaaacca gacctgcgac atggcccgtc aacagagggc tcagacatta cgagttcgga
      901 ccaagcacac ttcgggtctc agttacgggc aagaatctgg accagatgac atcaagccgt
      961 gcccacgatg cagtgcttac attatcaaga tgaacgacgg cagctgtaat cacatgacct
     1021 gtgcagtgtg tggctgtgag ttctgctggc tctgcatgaa agagatctct gacttgcatt
     1081 acctcagtcc ctctggctgt acattctggg gcaagaaacc atggagccgc aaaaagaaga
     1141 ttctttggca gttgggcaca ctgattggtg ctccggtggg gatctcactc atcgctggca
     1201 ttgccattcc cgccatggtc attggcatcc ccgtgtacgt ggggaggaag attcacagca
     1261 ggtatgaggg aaggaaaacc tccaagcaca agaggaattt ggccattaca ggaggagtga
     1321 ccttgtcagt catcgcatcc ccagtcatcg ctgctgttag cgttggtatt ggtgtcccca
     1381 ttatgctggc gtatgtttat ggggttgtgc ccatttctct ctgccgtgga ggtggctgtg
     1441 gagttagcac agccaatgga aagggggtaa aaattgaatt tgatgaagat gatggtccaa
     1501 tcacagtggc agatgcctgg cgagccctca aaaaccccag cattggagaa agcagcatcg
     1561 agggcctgac tagtgtgctg agcaccagcg gaagccctac agacgggctc agcgtcatgc
     1621 aggggcccta cagcgaaaca gccagctttg ctgccctttc agggggcaca ctgagtggtg
     1681 gcattctctc cagtggcaag ggaaaataca gccggttaga agttcaggcc gatgtccaaa
     1741 aggaaatttt ccccaaagac acagccagcc ttggtgcaat tagtgacagc gcaagcacgc
     1801 gtgctatggc cggttccata atcagctcct acaacccaca ggacagagag tgcaacaata
     1861 tggaaatcca agtggacatt gaagccaaac caagtcacta tcagttggtg agtggcagca
     1921 gcacagagga ctcgctccat gtccatgctc aggtggcaga gaatgaagaa gagggtaatg
     1981 gtggcggtgc tggcggtggc agtggtggca gtgaagacga tcccccttac aaacaccaaa
     2041 gctgtgaaca gaaagactgc ctggccagca aggcttggga catcagcctg gcgcagcctg
     2101 aaagcatccg cagtgacctg gagagctctg acacacagtc ggatgatgtg ccggacatca
     2161 cctcagatga gtgtggctca ccccgccccc acactgcggc ctgcccctcc accccccgag
     2221 tccacggtgc accgagccca agtgcccaca agagcctcgc tgctccagcc gagggccaga
     2281 ctgtcttgaa gccagaagag tatgaagtgg agtgaaggcc cctgctctga gaagcacact
     2341 tgttgtaact gcatcttttg gaatcttttt tgggggaggg tggggattta tgtattttgt
     2401 ttcaaagatt ctctggtcag ggttccccca ggggagttct gagaaatttg caatttctta
     2461 ccagataaaa aatgaaattt gcctctagta tccctccccc atcctcttgt ttttagtttt
     2521 aatttattgg ctaaactgat gttggcaatc tgtgaggtgt gtcaaagaat gtacatatgt
     2581 atgtgtgtat attgtatgta tgctaacatt attgatgaca cattttaata aagaattctg
     2641 tggtaactga
//
