LOCUS       NM_001130560            4187 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ring finger protein 19A, RBR E3 ubiquitin protein
            ligase (Rnf19a), mRNA.
ACCESSION   NM_001130560 XM_001059414 XM_343228
VERSION     NM_001130560.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4187)
  AUTHORS   Park,H., Yang,J., Kim,R., Li,Y., Lee,Y., Lee,C., Park,J., Lee,D.,
            Kim,H. and Kim,E.
  TITLE     Mice lacking the PSD-95-interacting E3 ligase, Dorfin/Rnf19a,
            display reduced adult neurogenesis, enhanced long-term
            potentiation, and impaired contextual fear conditioning
  JOURNAL   Sci Rep 5, 16410 (2015)
   PUBMED   26553645
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4187)
  AUTHORS   Rivkin,E., Kierszenbaum,A.L., Gil,M. and Tres,L.L.
  TITLE     Rnf19a, a ubiquitin protein ligase, and Psmc3, a component of the
            26S proteasome, tether to the acrosome membranes and the head-tail
            coupling apparatus during rat spermatid development
  JOURNAL   Dev Dyn 238 (7), 1851-1861 (2009)
   PUBMED   19517565
  REMARK    GeneRIF: Rnf19a and Psmc3 may interact directly or indirectly with
            each other, presumably pointing to the participation of the
            ubiquitin-proteasome system in acrosome biogenesis, spermatid head
            shaping, and development of the head-tail coupling apparatus and
            tail.
REFERENCE   3  (bases 1 to 4187)
  AUTHORS   Ebstein,F., Lange,N., Urban,S., Seifert,U., Kruger,E. and
            Kloetzel,P.M.
  TITLE     Maturation of human dendritic cells is accompanied by functional
            remodelling of the ubiquitin-proteasome system
  JOURNAL   Int J Biochem Cell Biol 41 (5), 1205-1215 (2009)
   PUBMED   19028597
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473950.2.
            
            On or before Jul 28, 2008 this sequence version replaced
            XM_001059414.1, XM_343228.3.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760389,
                              SAMEA5760434 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4187
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q22"
     gene            1..4187
                     /gene="Rnf19a"
                     /gene_synonym="Rnf19"
                     /note="ring finger protein 19A, RBR E3 ubiquitin protein
                     ligase"
                     /db_xref="GeneID:362900"
                     /db_xref="RGD:1307807"
     exon            1..155
                     /gene="Rnf19a"
                     /gene_synonym="Rnf19"
                     /inference="alignment:Splign:2.1.0"
     exon            156..918
                     /gene="Rnf19a"
                     /gene_synonym="Rnf19"
                     /inference="alignment:Splign:2.1.0"
     CDS             245..2767
                     /gene="Rnf19a"
                     /gene_synonym="Rnf19"
                     /EC_number="2.3.2.27"
                     /note="ring finger protein (C3HC4 type) 19; ring finger
                     protein 19A, E3 ubiquitin protein ligase"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase RNF19A"
                     /protein_id="NP_001124032.1"
                     /db_xref="GeneID:362900"
                     /db_xref="RGD:1307807"
                     /translation="MQEQEISFIFKYNEGLCMNIDSDSVLMSILDMSLHQQMGSDRDL
                     QSSASSVSLPSVKKAPKKRRISIGSLFRRKKDNKRKSRELTGGVDGIASIESIRSEVC
                     AEKNSIFSTNASSDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLR
                     QYLRIEISESRVNISCPECTERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRW
                     CPAPDCGYAVIAFGCASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLR
                     LRTIRSSSISYSQESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMK
                     EISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPV
                     YVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGIGVPIMLAYVYGVV
                     PISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNTAIDTTSVAEARHNPSIGEGSV
                     GGLTGSLSASGSHMDRIGTMRDNLSETASTMALAGASITGSLSGSAMVNCFNRLEVQA
                     DVQKERCSLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLDREGNSMEVQVDIESKP
                     FKFRHHSGSSSVDDGGAARGHASGSSSGLPEGKSSATKWSKEATGGKKSKSGKLRKKG
                     NTKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSVADSHSSHFSEFSCSDLESMR
                     TSCSHGSSDCHARFTAVNTLPEVENDRLENSPHQCSGSLLSKTASCSEVPQPSHAADE
                     RATSSGGGKAAVDVCFGDALRETNNNHSHQAADLKVAVQTEI"
     exon            919..1127
                     /gene="Rnf19a"
                     /gene_synonym="Rnf19"
                     /inference="alignment:Splign:2.1.0"
     exon            1128..1272
                     /gene="Rnf19a"
                     /gene_synonym="Rnf19"
                     /inference="alignment:Splign:2.1.0"
     exon            1273..1435
                     /gene="Rnf19a"
                     /gene_synonym="Rnf19"
                     /inference="alignment:Splign:2.1.0"
     exon            1436..1550
                     /gene="Rnf19a"
                     /gene_synonym="Rnf19"
                     /inference="alignment:Splign:2.1.0"
     exon            1551..1712
                     /gene="Rnf19a"
                     /gene_synonym="Rnf19"
                     /inference="alignment:Splign:2.1.0"
     exon            1713..1926
                     /gene="Rnf19a"
                     /gene_synonym="Rnf19"
                     /inference="alignment:Splign:2.1.0"
     exon            1927..2070
                     /gene="Rnf19a"
                     /gene_synonym="Rnf19"
                     /inference="alignment:Splign:2.1.0"
     exon            2071..4187
                     /gene="Rnf19a"
                     /gene_synonym="Rnf19"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcccgcaac cgttccaccg gcagctctct ccctagctga gaaggttccg cggcggtgct
       61 gaagagccgt cctccgttct tcctccgcgt tttgcctccg cgggatgggc ctgctcaccg
      121 gccgccctgc gccgccgccg ccctgaggag ctgaggacat ctgtgacaac agtcttctct
      181 tgaacttttt caagattctc tgaagaagcc aatgggatct tttttacatt atgatttaat
      241 ctgaatgcaa gaacaagaaa taagttttat ttttaagtat aatgaaggac tgtgtatgaa
      301 cattgattct gactcagttc tgatgagcat tttagacatg agtttacatc agcaaatggg
      361 ttcagataga gatctccaat cgtctgcttc gtctgtgagc ttgccttctg tcaaaaaggc
      421 acccaaaaag agaagaattt caataggctc tctctttcgg aggaagaagg acaacaaacg
      481 taaatcaagg gagctcactg gtggggtgga tggaattgca agtatagaaa gcatacgttc
      541 tgaagtgtgt gctgagaaga actccatttt ctctacaaac gcctcttctg acaatggatt
      601 gacgtccatc agcaaacaaa ttggagactt tatagaatgt cctttgtgcc ttttgcggca
      661 ttctaaagac agatttcctg atataatgac atgtcaccat agatcttgcg tggattgcct
      721 acgacagtac ctaaggatag aaatctctga aagtagagtt aatatcagtt gtccagaatg
      781 cactgaacgg tttaatcccc atgacattcg cttgatatta agtgatgatg tcttaatgga
      841 aaaatatgaa gaatttatgc ttcgacggtg gcttgttgca gatcctgact gtaggtggtg
      901 tccggctcca gactgtggat atgctgtgat agcctttgga tgtgccagct gtccaaaatt
      961 aacttgtgga cgagaaggct gtggaacaga gttttgctac cactgtaaac agatctggca
     1021 tccaaaccag acctgtgatg ctgctcggca ggaaagagcc cagagtttac gcttaagaac
     1081 catacgttct tcatccatta gttacagcca ggagtctgga gcagcagctg atgatataaa
     1141 gccgtgtcca cgatgtgctg cttatataat aaagatgaac gatgggagct gtaatcacat
     1201 gacgtgtgct gtctgtggct gtgagttttg ttggttgtgt atgaaagaaa tctctgattt
     1261 acattatcta agtccctcag gttgtacttt ttgggggaag aaaccctgga gccgaaagaa
     1321 gaaaatcctg tggcagctgg gaaccctggt cggtgctccc gtagggatcg ctctcatagc
     1381 tggcattgcc atccccgcca tgatcattgg cattcctgtg tacgtgggcc gcaagattca
     1441 taatcgctat gaaggcaaag atgtttcaaa acacaagcgg aatttggcca tagcgggtgg
     1501 tgtgacactg tctgtgatcg tgtctccagt ggtagccgca gtgaccgtag gcattggtgt
     1561 tcctatcatg ttagcttatg tctatggtgt tgtcccaatt tccctctgcc gaagtggggg
     1621 ctgtggagtt tctgcgggca atgggaaagg agtcaggatc gaatttgatg atgaaaacga
     1681 cataaacgtt ggtgggacta acacagccat agatacaaca tcagtagcag aagcaaggca
     1741 caaccctagc ataggagaag gaagtgtggg cggtctgact ggcagcttga gtgcaagtgg
     1801 aagccacatg gatcgaatag gcaccatgag agacaacctg agtgagacag ccagcaccat
     1861 ggcattagct ggggccagta tcaccggcag cctgtcagga agcgccatgg taaactgttt
     1921 caacaggttg gaagtacaag ccgacgtaca gaaggagcgg tgcagcctca gtggagaatc
     1981 gggcacagtg agcttgggga cagtcagtga taatgccagc accaaagcga tggcagggtc
     2041 cattctgaat tcttacatcc ctctggacag agaagggaac agtatggaag tgcaagtgga
     2101 tattgagtca aagccattca agttccgaca ccacagtgga agcagtagtg tggatgatgg
     2161 cggcgctgcc cgaggccacg caagcgggtc atccagtggc ttgcctgaag gtaaatccag
     2221 tgctaccaag tggtccaaag aagcaacagg aggaaaaaag tcaaaaagtg gtaaactgag
     2281 gaaaaagggt aacacgaaga taaatgagac cagagaggac atggatgcac agttgttaga
     2341 gcaacagagc actaactcaa gtgagtttga ggcgccgtcc ctcagtgaca gtatgccgtc
     2401 tgtagcagac tcccactcga gtcatttttc tgaatttagc tgctcagact tagagagcat
     2461 gagaacgtcc tgtagtcacg gttccagcga ttgccacgcc cgcttcacag ctgtgaacac
     2521 ccttcctgag gtagaaaatg accgtctgga gaattcacca caccagtgta gcggttctct
     2581 gctttccaaa actgcttcct gttcagaagt gccccagccg agccatgctg cagatgagcg
     2641 agccaccagc agtggtgggg ggaaggcagc tgtggatgtg tgctttggcg atgccctgag
     2701 agagacaaat aacaaccact cgcaccaggc agcagacttg aaagttgctg ttcagactga
     2761 aatttaggcc cacgaatgcc gcagaggaat aaccactgaa caaccttgtg ggagctggtt
     2821 gaaccatgtg cgactgttaa gcttaagtta ccagcagaag ccaggtttca taatcataat
     2881 gcaaatacat tttgtatgtc tagcaaagca ttgtgcttca tgtggatatt aattaccaaa
     2941 tgaggaaatg aaggctttaa agtgcattag tgcgcgaata acaacataaa aaaggcatgt
     3001 tttgtgctct tgtcacaaaa cactgctgga cacacatacc tgtgtattta gatagaaatt
     3061 tggcttaatt tataatctta tgatactaac actgttctat ggcattctta aggaagattg
     3121 aggcttaggg ataagtggtt agtgacattt tattgaaacc actaagggat ggaacgtggc
     3181 agattactca gtgtatgatc tctttgtaac atttctcttc ataactgagc ttacacttca
     3241 tttcttcata tgcagtgtgg atacaaagct tgatgcagcc cattggtaac catggatact
     3301 tagacacttg agaagagtgt ggctgtgttt gcacaactct gaagtagaaa taaatacttg
     3361 gtactgttac atatttcgtg tattgttgat gccattttag aagaagaagg taaaagtaag
     3421 taactgacag tggcagaata aaatcccatt aggacataag tattacagtc acctgtcgct
     3481 aaggaaagtt agtgcccttg atccttggtg cctctagggg agactgggtt tatgagcctc
     3541 atcatttgag gatttgctct atcatttccc ataatgtctt ctctagtcac cttggattat
     3601 atagaaaagt acaggaaata ggtaaacatg aatgtgatta ttaactacac tgaaaagtat
     3661 tcacctacca aagacacact caggcgttag taaatttaac tttacataac ctcaattttt
     3721 aacatgtata tctttttgaa ccatgaaatc aaaacaatgc agagcttgta ccaagcttat
     3781 tcaaaaggtc tacgtgtggc tttgtttcct tttgcttttg tttacggagg atgatcagct
     3841 gacacagcag aagttggcca aaatgctggc tacactattg acttccccac agctccccgg
     3901 caggctaacc ttacagcagt caagtactcc acctttggtg tttcttttaa gtattaccat
     3961 tatggtgcta ctgagcattt tcttttggaa aacaaggaaa atgtccgggc tgcagtcttg
     4021 taccgccgtt ctcgctgcgt ccattagtct gcttagataa cactagtgcc agttctgtta
     4081 gctgatactg ctcattattg tgtgtacatt tgtttgcatt ccagttttgt tcagtaatga
     4141 gtgtgtaaac agcagacatg aaataaatgt aaatactaat ggatttg
//
