LOCUS       NM_001164264            1905 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ring finger protein 187 (Rnf187), mRNA.
ACCESSION   NM_001164264 XM_001076738 XM_340805
VERSION     NM_001164264.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1905)
  AUTHORS   Davies,C.C., Chakraborty,A., Cipriani,F., Haigh,K., Haigh,J.J. and
            Behrens,A.
  TITLE     Identification of a co-activator that links growth factor
            signalling to c-Jun/AP-1 activation
  JOURNAL   Nat Cell Biol 12 (10), 963-972 (2010)
   PUBMED   20852630
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            FM033519.1, DY320214.1, DY569693.1 and CK599682.1.
            
            [WARNING] On Jan 13, 2025 this sequence was replaced by
            NM_001164264.2.
            
            On or before Aug 21, 2009 this sequence version replaced
            XM_340805.3, XM_001076738.1.
            
            Sequence Note: The annotated protein is predicted to be translated
            from a non-AUG start codon based on cross-species sequence
            conservation, and includes a RING domain that would not be present
            if translation were to initiate from the first in-frame AUG.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DY320214.1, CV113869.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00155312, SAMEA5760383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            non-AUG initiation codon :: inferred from conservation
            RefSeq Select criteria   :: based on single protein-coding
                                        transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-352               FM033519.1         1-352
            353-1023            DY320214.1         1-671
            1024-1322           DY569693.1         401-699
            1323-1905           CK599682.1         1-583               c
FEATURES             Location/Qualifiers
     source          1..1905
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q22"
     gene            1..1905
                     /gene="Rnf187"
                     /gene_synonym="RACO-1; RGD1308636"
                     /note="ring finger protein 187"
                     /db_xref="GeneID:360533"
                     /db_xref="RGD:1308636"
     exon            1..467
                     /gene="Rnf187"
                     /gene_synonym="RACO-1; RGD1308636"
                     /inference="alignment:Splign:2.1.0"
     CDS             78..788
                     /gene="Rnf187"
                     /gene_synonym="RACO-1; RGD1308636"
                     /EC_number="2.3.2.27"
                     /note="non-AUG (CUG) translation initiation codon; RING
                     domain AP1 coactivator 1; RING-type E3 ubiquitin
                     transferase RNF187"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase RNF187"
                     /protein_id="NP_001157736.1"
                     /db_xref="GeneID:360533"
                     /db_xref="RGD:1308636"
                     /translation="MALPAGPAEAICALCQRAPREPVRADCGHRFCRACVVRFWAEED
                     GPFPCPECADDCWQRAVEPSRPPLSRRLLALEEAAAAPARDGPASEAALQLLCRADGD
                     PLCSACRMAAGPEPPEWEPRWRKALRGKENKGSVEIMRKDLNDARDLHGQAESAAAVW
                     KGHVMDRRKKALTDYKKLRAFFVEEEEHFLQEAEKDEGASDDDELADPADRFRSLLQA
                     VSELEKKHRNLGLSMLLQ"
     exon            468..560
                     /gene="Rnf187"
                     /gene_synonym="RACO-1; RGD1308636"
                     /inference="alignment:Splign:2.1.0"
     exon            561..785
                     /gene="Rnf187"
                     /gene_synonym="RACO-1; RGD1308636"
                     /inference="alignment:Splign:2.1.0"
     exon            786..1891
                     /gene="Rnf187"
                     /gene_synonym="RACO-1; RGD1308636"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1870..1875
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rnf187"
                     /gene_synonym="RACO-1; RGD1308636"
     polyA_site      1891
                     /gene="Rnf187"
                     /gene_synonym="RACO-1; RGD1308636"
ORIGIN      
        1 gccttgctct ctggccggtc ctcggccctt ctgcgccctc tctgcccgcg tcctcgtcgg
       61 cgccgccgcc cgcagccctg gcgctccccg cgggccccgc tgaggccatc tgcgccttgt
      121 gtcagcgcgc gccccgcgaa ccggtgcgcg ctgactgcgg ccatcgtttc tgccgggcgt
      181 gcgtggtgcg cttctgggcc gaggaggacg ggcccttccc atgccccgag tgtgccgatg
      241 actgctggca gcgcgcggta gagcccagcc gcccaccact gagccgccgc ctcttggcgc
      301 tcgaggaggc ggccgcggcg ccggcgcgcg atggccctgc tagcgaggcc gcgttgcagc
      361 tgctatgccg tgccgacgga gatccgctgt gctctgcttg ccgcatggcc gccggtccgg
      421 agccgcctga gtgggaaccg cgttggagga aggcgctgcg tggcaaggag aacaagggct
      481 ctgtggaaat catgaggaag gacttaaatg atgcccggga cctgcatggt caggcagaat
      541 ccgctgctgc tgtgtggaag gggcatgtta tggaccgaag aaagaaggcc ctgactgact
      601 ataagaagct tcgggccttc ttcgtggagg aggaggaaca ctttctgcaa gaggctgaga
      661 aggatgaggg tgcttctgat gacgatgagc tggctgaccc ggcagatcgc ttccggtcgc
      721 tgctgcaggc ggtgtcagag ctggagaaga agcaccgtaa cctgggcctt agcatgcttc
      781 tgcagtgatg acgctggcgc agcaggctgg ccccctggag ctcgaggcaa aaggaaccac
      841 cttccacagc tggcctgcag cacccctacc tacatccctt aggcctctgc ctggcatctc
      901 ttcatcctgg acagacccct atctccatca acaccgacag cgcgctggcc tgggatgaag
      961 cctcagaggt gccctgcttt ggccatgcac atagttccat tgttcagcag tgttttttgt
     1021 tttctttggg gcatgaatgt gctcgggcct gttcctgttc cacatagaga ccgacctgtc
     1081 ctgggattcc tttcccagtg tgtgccaacc ctgcctgaga ccacttggca gctctgaagc
     1141 ccctgcttct tgttttgcca tggcttggct tatgtggcgt tcactctagt atctaggaac
     1201 caaaccttgc gccttcccta ttggtgcctg tgccgggttg gctcactaga cattcctcag
     1261 caaggctctg aggcatagca gttacagtca gtctgtgtca gtgccaggga atagggatgt
     1321 aggaggccct ggggtatggc tgggaaccga gtattaacaa agtattctcc accctccaga
     1381 ggacctcttc tctctctttg ggtctcactg tgccaggtcc tgggagccat cttctgcctt
     1441 gcttccccag cctcttttcc tcccagcttg tgccccttgg gtgtcactgg cgtccccaga
     1501 gtgctcccta cttctcccca cctctcatgg acaggacctt cttccctgca gaagagcagc
     1561 agggtggcat ctccaggcca ccgggtgctt cacttcgctg tatttttggc ttttgctcac
     1621 ctcattttct ccagtaggtg aatctcacag aacttgtgac gtagcggtag cgtggttgcc
     1681 tgcagcatct tgtgtgtaga taactagtcc aagagacaaa acccagcaga gtggacagac
     1741 acaggccagg gccaaacaca tagatggatt taggtttggg gaacagtgtt ctgtcctcag
     1801 aaggccccag ccttggatgt ggtgaccggc tccagcttga ctcccaggtg ggctgggttt
     1861 tcagtgctga ataaagtggt ttgctccagc caaaaaaaaa aaaaa
//
