LOCUS       NM_001024271            2786 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ring finger protein 185 (Rnf185), mRNA.
ACCESSION   NM_001024271 XM_573638
VERSION     NM_001024271.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2786)
  AUTHORS   Kaneko,M., Iwase,I., Yamasaki,Y., Takai,T., Wu,Y., Kanemoto,S.,
            Matsuhisa,K., Asada,R., Okuma,Y., Watanabe,T., Imaizumi,K. and
            Nomura,Y.
  TITLE     Genome-wide identification and gene expression profiling of
            ubiquitin ligases for endoplasmic reticulum protein degradation
  JOURNAL   Sci Rep 6, 30955 (2016)
   PUBMED   27485036
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2786)
  AUTHORS   El Khouri,E., Le Pavec,G., Toledano,M.B. and Delaunay-Moisan,A.
  TITLE     RNF185 is a novel E3 ligase of endoplasmic reticulum-associated
            degradation (ERAD) that targets cystic fibrosis transmembrane
            conductance regulator (CFTR)
  JOURNAL   J Biol Chem 288 (43), 31177-31191 (2013)
   PUBMED   24019521
REFERENCE   3  (bases 1 to 2786)
  AUTHORS   Girard,A., Sachidanandam,R., Hannon,G.J. and Carmell,M.A.
  TITLE     A germline-specific class of small RNAs binds mammalian Piwi
            proteins
  JOURNAL   Nature 442 (7099), 199-202 (2006)
   PUBMED   16751776
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC092655.1.
            
            On May 27, 2005 this sequence version replaced XM_573638.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC092655.1, FN801244.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840111 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2786
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14q21"
     gene            1..2786
                     /gene="Rnf185"
                     /note="ring finger protein 185"
                     /db_xref="GeneID:360967"
                     /db_xref="RGD:1564777"
     exon            1..107
                     /gene="Rnf185"
                     /inference="alignment:Splign:2.1.0"
     exon            108..328
                     /gene="Rnf185"
                     /inference="alignment:Splign:2.1.0"
     CDS             153..731
                     /gene="Rnf185"
                     /EC_number="2.3.2.27"
                     /note="RING-type E3 ubiquitin transferase RNF185"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase RNF185"
                     /protein_id="NP_001019442.1"
                     /db_xref="GeneID:360967"
                     /db_xref="RGD:1564777"
                     /translation="MASKGPSASASTENSSAGGPSGSSNGTGESGGQDSTFECNICLD
                     TAKDAVISLCGHLFCWPCLHQWLETRPNRQVCPVCKAGISRDKVIPLYGRGSTGQQDP
                     REKTPPRPQGQRPEPENRGGFQGFGFGDGGFQMSFGIGAFPFGIFATAFNINDGRPPP
                     AVPGTPQYVDEQFLSRLFLFVALVIMFWLLIA"
     exon            329..347
                     /gene="Rnf185"
                     /inference="alignment:Splign:2.1.0"
     exon            348..460
                     /gene="Rnf185"
                     /inference="alignment:Splign:2.1.0"
     exon            461..515
                     /gene="Rnf185"
                     /inference="alignment:Splign:2.1.0"
     exon            516..633
                     /gene="Rnf185"
                     /inference="alignment:Splign:2.1.0"
     exon            634..2759
                     /gene="Rnf185"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttcggaggtt caatcttcct gactgacgcg tctctaagac tggcttgtcc actgtgggac
       61 aggggaacgg actggtggcg tcgctggcgc tcgctctacg gggacaggat tgtcttgaga
      121 atcttcgctg aaagcttttc tggcaagcag ctatggcaag taaagggccc tcggcctctg
      181 catccactga gaattccagt gcaggggggc ccagtggcag cagcaatggc actggtgaga
      241 gtggagggca ggacagcacc ttcgaatgca acatatgtct ggacacagcc aaggacgctg
      301 tcatcagcct gtgtggccac cttttctgtt ggccgtgttt acatcagtgg ttggagacta
      361 gacctaacag acaagtatgt ccagtttgca aagcgggaat cagccgggac aaggtcatcc
      421 cactctatgg cagaggcagc actggacagc aggatcccag agagaagact cctcctcgtc
      481 ctcaaggcca gaggccagag ccagaaaata gagggggatt tcaaggattt ggatttggag
      541 atggtggctt tcagatgtct tttggaattg gagcatttcc atttgggata tttgccacag
      601 catttaacat aaatgatggg cgacctcctc cagccgtccc tgggacaccc cagtatgtgg
      661 atgagcagtt cctgtcacgc ctcttcctgt ttgttgccct ggtgatcatg ttctggctcc
      721 tgatcgccta agacaggacc ctgtttactt ctacagcagc acctctgggc tggtgatatg
      781 ccgaacccac tcctgtgttt gatttgttta atcccgaccc tggaatcaag gggcagaaac
      841 acatcaagga gtcttgcttc tccattgagc tttgggactc gaaagcagtt ggcgaggaac
      901 ccccactttc accactgctg cacacacact ataacctcag gtcttgtgtt gactcactgc
      961 tcctgggtgg caatgggaag tcctgaccca gtctgctcag tagtcccagc tctgcacagg
     1021 ggagacgggg gaagaaagaa acagttcttt ctcgagaact ttaaattaca aaaaatgaag
     1081 ggatgaacca cacggtattc acagacactt tcatctttta catacccctt ggtaagtggc
     1141 ctccactccc tatcctgaga gactcccttc cacagcccag tactgctcct cccgccttcc
     1201 ccttccacag caaagacaaa gagttgctgc ccaagaaggc catgatcgta gcagcagaag
     1261 ttgaagatgc tgcatgacct taccagggac tctggtcctg gcttggccct gggcctcgtt
     1321 cagtgtctcg gccctagagc agctgggatg acctgctgtc ttcctggtgt agattgtccc
     1381 tgatgccact tggctcagat tcccatcctc cttctcccct aggctgctgt tgaattcaga
     1441 ctgatgcagc ttcagggctg atgcaggagc aacaggacag gtagccccgc ccctaggctg
     1501 gagaagcccg agtcatcctc tcccagaact tgcccagaga aactggaggc cttctcaggt
     1561 cagcctagct acatgtaaca ccaccaccct cagaagccat tgtccttttt taaaagagac
     1621 tgggactctg attccatctg ctgttggttt ggcttcctgg atttacctga aaactccttg
     1681 aatgtgtgct gaacccaggg acacatgagg ctcctgagcc agcaacccct ggtgacatgc
     1741 aatgcaagga ctgcagagac acagtgtggt cgtcattcct attccctcac attgatttgt
     1801 tcttgaactt ccaagctgtt tcctctgaat ctgattgtgg gattgtggtg ccaggcagga
     1861 gaacaattca cttgctaaga cagttctcac tctgcctgtc aggcctcatc ttagaagtgt
     1921 cacctcagca gggcagcacg atgagcttct gctggaccct tgttcacttc tccggcacct
     1981 actgccccag cagtaacaga cgcgggagaa agcctggcct gctgggtttt caagatgtga
     2041 ctctgcataa tctatggagc cctagacctt gagggtgtga aagaatcctc ctcctcactg
     2101 cacagtcctc acctgccgat gccagtgtta gtgttgaaat gagcacagta tgaagtattg
     2161 tgtaggaggg tggtttggca actgtagctg gtaagaataa gccaccaact tcatggtgtg
     2221 cctgacagat tttaaatatt ctttgtcgct tggaaatcct gtcagagggc cctggagtgt
     2281 ctctgttcta gagagagttg gtaggatcct tctgtgtagt gtggccctaa gtagtagagg
     2341 gaaaacgtaa gccaatgaac acaaaagaga gaaaagttgt gagtagtgga gtaaaccatt
     2401 tgtaagctgg tgaaatggcc aacccaggcg tgcaccagca gtcatcccaa ggcatgcagt
     2461 agcacagctg tggcggcctg tgccctttgt gagcattgca gggctgtaca tctgccagca
     2521 gctgaggcaa gagagcagct tggatgccat gggccgttcc tccacaggct caccactcac
     2581 ctcatggccc aggcagcttt cccttctggg ctctctgtgt cctcagctcc acctttccgc
     2641 ctcccccatg gacaaggaca gtcagaaaat gggaacacag aaggcagcat accttgacca
     2701 gccattgatt ttcactgttg tgaaagtgat ttgatttaga attaaatggt tttacattaa
     2761 aaaaaaaaaa aaaaaaaaaa aaaaaa
//
