LOCUS       NM_001007647            1831 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Rattus norvegicus ring finger protein 181 (Rnf181), mRNA.
ACCESSION   NM_001007647 XM_216174
VERSION     NM_001007647.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1831)
  AUTHORS   Pedersen,S.M., Chan,W., Jattani,R.P., Mackie,d.S. and
            Pomerantz,J.L.
  TITLE     Negative Regulation of CARD11 Signaling and Lymphoma Cell Survival
            by the E3 Ubiquitin Ligase RNF181
  JOURNAL   Mol Cell Biol 36 (5), 794-808 (2015)
   PUBMED   26711259
  REMARK    Erratum:[Mol Cell Biol. 2016 Mar 31;36(8):1322. doi:
            10.1128/MCB.00106-16.. PMID: 27034408]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1831)
  AUTHORS   Lee,Y.I., Giovinazzo,D., Kang,H.C., Lee,Y., Jeong,J.S.,
            Doulias,P.T., Xie,Z., Hu,J., Ghasemi,M., Ischiropoulos,H., Qian,J.,
            Zhu,H., Blackshaw,S., Dawson,V.L. and Dawson,T.M.
  TITLE     Protein microarray characterization of the S-nitrosoproteome
  JOURNAL   Mol Cell Proteomics 13 (1), 63-72 (2014)
   PUBMED   24105792
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079313.1.
            
            On Nov 29, 2004 this sequence version replaced XM_216174.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079313.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
FEATURES             Location/Qualifiers
     source          1..1831
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q32"
     gene            1..1831
                     /gene="Rnf181"
                     /note="ring finger protein 181"
                     /db_xref="GeneID:297337"
                     /db_xref="RGD:1359698"
     exon            1..54
                     /gene="Rnf181"
                     /inference="alignment:Splign:2.1.0"
     exon            55..535
                     /gene="Rnf181"
                     /inference="alignment:Splign:2.1.0"
     CDS             411..908
                     /gene="Rnf181"
                     /EC_number="2.3.2.27"
                     /note="RING-type E3 ubiquitin transferase RNF181"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase RNF181"
                     /protein_id="NP_001007648.1"
                     /db_xref="GeneID:297337"
                     /db_xref="RGD:1359698"
                     /translation="MASYFDEHDCEPLNPEREARNNMLLELARRVRGAWSWAPGSRSL
                     FNRMDFEDLGLVDWEHHLPPPAAKAVVESLPRTVIRSSKAELKCPVCLLEFEEEETVI
                     EMPCHHLFHSNCILPWLSKTNSCPLCRHELPTDDDSYEEHKKDKARRQQQQHRLENLH
                     GAMYT"
     exon            536..663
                     /gene="Rnf181"
                     /inference="alignment:Splign:2.1.0"
     exon            664..773
                     /gene="Rnf181"
                     /inference="alignment:Splign:2.1.0"
     exon            774..848
                     /gene="Rnf181"
                     /inference="alignment:Splign:2.1.0"
     exon            849..1795
                     /gene="Rnf181"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgccttcaag gtcataggaa ggatcactca tgggctggca cgatggtttg gcagggagta
       61 gatggaacat gagggtagac tcagccatca agacacggta gaggcgcttt cggtttggac
      121 tggcacttct ggagctttgc gagaaccctc ggagcttggc tccggaaaga ccccggaatt
      181 tcctctttct ccaactacat ttgctttagc ctttggtcac ctgactcatc cgaccaacga
      241 gaggcggctg aatcagtact tccgcctctg tgtgcgagtc actatgccca cctcaggaat
      301 tctctgattg gctgtccttc cgaaactcgc tcgcttattg gccatcgcgg gattcggctc
      361 tccagcggca acctaaagct gtgtcagaca agcccggcag cccagtagcc atggcgtctt
      421 attttgatga gcacgactgc gagccgttga accctgagcg tgaggcccgc aacaatatgt
      481 tgctagaact cgcgagaaga gtgcgcgggg cttggagttg ggcccctggc agcagatcac
      541 tctttaatag gatggacttt gaggacctgg gattggtaga ttgggaacac caccttcccc
      601 caccagctgc caaggctgtg gtggagagcc tccccagaac agtcatccgt agctccaagg
      661 ctgagctcaa gtgtcccgtg tgtcttttgg aatttgagga ggaggagact gtcattgaga
      721 tgccctgcca tcatctcttc cattccaact gcattctgcc ctggttaagt aagacaaatt
      781 cctgccctct gtgccgccat gagctgccca ccgatgacga cagttatgaa gagcacaaga
      841 aagacaaggc tcggaggcag cagcagcagc accgcctgga gaacctccat ggagccatgt
      901 acacgtgagg cagcagctag ggctgagagc tcagcctctg tgatatcttc cctttgcact
      961 ttgaatcttc attaaaggtt tctttaacca ccctgcagct gcactgctca ccagctgaag
     1021 gggcttcgtc cgaatcctcc aacctgctgc tagccagaaa gatgtcaaag gtgtcaaaag
     1081 gcagaaggtg ccgggctgca tttccctctc tgccagtctc tagactctgg gtggtggagc
     1141 cctgggagca acaagggctt gggtctgagt gttcttttag aagtcaaact gtgtcagatc
     1201 ctggcacttt gtagctattt aaaactgata aattaacttg caccaccccc ttccggaaat
     1261 ctctagttaa ccttggaact ttagttaaca ttggaatcct gggagtgttc ttcatttcca
     1321 cagagaaaac ttgtaacatt gtcaaagttg ctctctgtat cctgcccctg taggcccctt
     1381 atcaaggaat caaagttcaa accagactga gtaggggaaa gaagttcttt agctgtttag
     1441 actctgaaag ggggacaagg ccttgtggag gttttgaaag tgggtttcac tatgtgacct
     1501 tggctggctt ggagcccact gtatagacca ggctggcctt gaacttagat tcttctgcct
     1561 ctaccttccc agtactggga ttgctggtat gtaccagcac tgtgctcaga cccttatgat
     1621 gtatttgaat ggcatctgtc actttgagtt cctggcaact ctcaagaatc ttttctggag
     1681 gaaaggactt ctttccaccc ctccctactg gatgggaccc tccctgattc tccagaacag
     1741 actgcaaaca tgcaaattag aattctttta atagatataa aaaagtacta aaataaaaaa
     1801 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
//
