LOCUS       NM_001134986            2680 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ring finger protein 180 (Rnf180), mRNA.
ACCESSION   NM_001134986 XM_001063572 XM_001064567 XM_001064629
VERSION     NM_001134986.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2680)
  AUTHORS   Kabayama,M., Sakoori,K., Yamada,K., Ornthanalai,V.G., Ota,M.,
            Morimura,N., Katayama,K., Murphy,N.P. and Aruga,J.
  TITLE     Rines E3 ubiquitin ligase regulates MAO-A levels and emotional
            responses
  JOURNAL   J Neurosci 33 (32), 12940-12953 (2013)
   PUBMED   23926250
REFERENCE   2  (bases 1 to 2680)
  AUTHORS   Ogawa,M., Mizugishi,K., Ishiguro,A., Koyabu,Y., Imai,Y.,
            Takahashi,R., Mikoshiba,K. and Aruga,J.
  TITLE     Rines/RNF180, a novel RING finger gene-encoded product, is a
            membrane-bound ubiquitin ligase
  JOURNAL   Genes Cells 13 (4), 397-409 (2008)
   PUBMED   18363970
REFERENCE   3  (bases 1 to 2680)
  AUTHORS   Florea,L., Di Francesco,V., Miller,J., Turner,R., Yao,A.,
            Harris,M., Walenz,B., Mobarry,C., Merkulov,G.V., Charlab,R.,
            Dew,I., Deng,Z., Istrail,S., Li,P. and Sutton,G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC168657.1.
            
            On Mar 11, 2021 this sequence version replaced NM_001134986.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168657.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2680              BC168657.1         1-2680
FEATURES             Location/Qualifiers
     source          1..2680
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q13"
     gene            1..2680
                     /gene="Rnf180"
                     /note="ring finger protein 180"
                     /db_xref="GeneID:685384"
                     /db_xref="RGD:1595064"
     exon            1..118
                     /gene="Rnf180"
                     /inference="alignment:Splign:2.1.0"
     CDS             119..1897
                     /gene="Rnf180"
                     /EC_number="2.3.2.27"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase RNF180"
                     /protein_id="NP_001128458.1"
                     /db_xref="GeneID:685384"
                     /db_xref="RGD:1595064"
                     /translation="MRRSEESTGTQSSEEQTGALRCWRCRKCIASSGCFMSPLETQAV
                     EDRHESVDAQNTCHLWHMNAEALPEWISCLVQKAQWTVGKLNCPFCGARLGGFNFVST
                     PKCSCGQLAAVHLCKSRTEHQATQAGRLTRPAPKCLPHPGVPSGCDKETLLTGGGSKT
                     RSHRLLSMARNNNGLGRLTEALCLEVRATYFEMKNEKLLFKTSDPKCQPFVPQPDTGR
                     CTSRASHRKSHSLDLNISEKLILLPTLYEIHSKPAAYPRVNETGPIDLSGLALPCSKS
                     NCSFQNPPSFDPSMLLHRLSVAPHETQAQRGREFQCGLEASSVYSDHAHANSLPFLMD
                     LPSAGRSMLEASDQEEHLSPLDFLRSASFPLGTINHRLNNRERNKLRTLRRQQRRRER
                     WLQKQGKYSGVGLLDHMTLSNEMSTDDEPEFTEEKDSYICAVCLDVYFNPYMCYPCHH
                     IFCEPCLRTLAKDNPASTPCPLCRTIISRVFLQTELNNATKTFFTKEYLKIKQSFQKS
                     SSAKWPLPSCRKGFHLFGGFHRRAAPVTRRQFPHGAHRMDYLHFEDDSRGWWFDMDMV
                     IIYIYSVNWVIGFVVFCFLCYFFFPF"
     exon            119..253
                     /gene="Rnf180"
                     /inference="alignment:Splign:2.1.0"
     exon            254..349
                     /gene="Rnf180"
                     /inference="alignment:Splign:2.1.0"
     exon            350..1309
                     /gene="Rnf180"
                     /inference="alignment:Splign:2.1.0"
     exon            1310..1345
                     /gene="Rnf180"
                     /inference="alignment:Splign:2.1.0"
     exon            1346..1571
                     /gene="Rnf180"
                     /inference="alignment:Splign:2.1.0"
     exon            1572..1697
                     /gene="Rnf180"
                     /inference="alignment:Splign:2.1.0"
     exon            1698..2680
                     /gene="Rnf180"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggctggccca gacgcctgct gattctagct gggaacagac ccagtgtgta gctagagtca
       61 gcactccaga ggcgctaggt gaagacgggg aagacaagca cagacttttg ttgctcggat
      121 gagaagaagt gaagagtcga caggcacgca gagcagtgag gagcagacag gagcccttcg
      181 ttgctggaga tgtagaaaat gcatcgcaag ttctggttgc ttcatgagtc ctcttgagac
      241 tcaagcggtt gaggacagac atgagtcagt cgacgcccaa aacacttgtc atctgtggca
      301 catgaacgca gaagcccttc cagaatggat aagctgccta gtgcaaaaag cccagtggac
      361 agttgggaaa ctgaattgtc ctttctgtgg ggcccgatta gggggcttta attttgtcag
      421 cactccaaaa tgttcctgtg gccagcttgc agctgtacat ctctgcaaga gccggactga
      481 acatcaagcg acacaggcag gcagactaac gagaccagcg ccgaaatgtt tgccacatcc
      541 cggggttccg tcaggttgtg acaaggaaac tctgctgaca ggtggtggct ccaaaacgag
      601 aagccacagg cttttaagca tggcccgaaa caataacggc cttggaagac tcacagaagc
      661 actctgcctg gaggtgagag cgacgtattt tgagatgaag aatgaaaaac tgctcttcaa
      721 aacatccgac ccaaaatgcc agccttttgt tcctcagcct gacaccggca ggtgcacttc
      781 aagagcttct cacagaaagt cacacagctt ggacctgaac atcagtgaga agctgatttt
      841 attgcccact ttgtatgaga tccacagtaa gcctgctgcc tatcccaggg taaatgaaac
      901 agggcccatt gacctttcag gcttggcttt accatgtagt aaaagtaact gctcctttca
      961 aaacccaccc agctttgatc ccagtatgct gctgcacaga ctgtcggtgg ccccccacga
     1021 gacccaggca caaaggggaa gagaattcca gtgtggccta gaagcttctt cagtctactc
     1081 agatcatgct catgctaaca gcctgccatt tctgatggat ctgccctcag cggggaggag
     1141 catgctggag gcctcggacc aagaagaaca cctctcccct ctggacttcc ttcgctctgc
     1201 cagcttcccc ttgggcacca ttaaccacag gctgaacaac agagagagga acaagttgag
     1261 gactctgaga aggcagcagc ggcggcgtga gcgatggcta cagaagcagg gtaaatactc
     1321 aggagtggga ttgctggatc acatgacctt gagtaatgag atgagtacag atgatgagcc
     1381 tgaattcaca gaggaaaagg acagctacat ctgtgcggtg tgcctggatg tgtacttcaa
     1441 cccctacatg tgctacccct gccatcacat cttctgcgag ccctgcctac gaactctggc
     1501 caaagacaac cctgcaagca ctccctgccc actgtgccgg acaattattt ctagagtctt
     1561 tctccagaca gagctgaaca atgccacaaa gacattcttt actaaagaat atttgaaaat
     1621 aaaacagagc ttccagaaat ccagctctgc gaaatggccc ttgccgagct gcagaaaagg
     1681 attccatctc tttggagggt tccacaggcg cgcggcccca gtgacgcgga ggcagttccc
     1741 acacggtgcc cacaggatgg actacctgca cttcgaggac gacagccgcg ggtggtggtt
     1801 tgacatggat atggtgatca tctatattta ttcagtgaac tgggtcattg gctttgttgt
     1861 tttctgcttc ctttgctatt ttttctttcc gttttaggaa tcgtcgtact ctgctacaat
     1921 tgaacagtca taaacgtaaa caatggcttg aacgttttga aggtgtgctt cgaagttttt
     1981 ataatgtcgc attataaaaa tggttagtgt ttataaaaaa gcctgaggat aatggattta
     2041 tttattaatt tctttcatgt aacaacctaa actttattca agagctggcg aaccagccat
     2101 tagaaacagt gcactattaa ctccatactt tttactttag gacctggggc tctaatttta
     2161 caatgtcatt tttatactta ctatgattgt aaagactgag gtttttacct ccatttaaaa
     2221 acagtaaaaa tatgaaatga aataatctgg atagatacca tcattattac taagatgttt
     2281 agtgaagcac tatgtattct taggcaaatg atgtctgtta aaaatagacc atgttctctg
     2341 ggaactaatc aagcagggta tattgcgatt ttgatttctg aatatctcta cttctgtctc
     2401 ctattaccaa aaatctgact atccttttgt aaagacttca tagctttggc gcaacgtttt
     2461 taactattgt aagcgcaaac taccacatgc agtgtgacta acacccaata gctatgttag
     2521 agagccatat taacactttc caatttcaga atggatcact ttagaaataa catatctgac
     2581 ttttagtaac ctaaatggcc aatgcatgtg caaactgtaa tcaacctggt gattcattta
     2641 actagataca ttgtcactgt gcaataaaga gtggctttta
//
