LOCUS       NM_001419669            4635 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus ring finger protein 157 (Rnf157), mRNA.
ACCESSION   NM_001419669 XM_039087473
VERSION     NM_001419669.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4635)
  AUTHORS   Matz,A., Lee,S.J., Schwedhelm-Domeyer,N., Zanini,D., Holubowska,A.,
            Kannan,M., Farnworth,M., Jahn,O., Gopfert,M.C. and Stegmuller,J.
  TITLE     Regulation of neuronal survival and morphology by the E3 ubiquitin
            ligase RNF157
  JOURNAL   Cell Death Differ 22 (4), 626-642 (2015)
   PUBMED   25342469
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Apr 13, 2023 this sequence version replaced XM_039087473.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.65262.1,
                                           SRR26643293.67502.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-338               JAXUCZ010000010.1  102138364-102138701 c
            339-457             JAXUCZ010000010.1  102120915-102121033 c
            458-546             JAXUCZ010000010.1  102094846-102094934 c
            547-693             JAXUCZ010000010.1  102093180-102093326 c
            694-811             JAXUCZ010000010.1  102092740-102092857 c
            812-878             JAXUCZ010000010.1  102092178-102092244 c
            879-922             JAXUCZ010000010.1  102091853-102091896 c
            923-970             JAXUCZ010000010.1  102091493-102091540 c
            971-1042            JAXUCZ010000010.1  102089032-102089103 c
            1043-1202           JAXUCZ010000010.1  102088218-102088377 c
            1203-1315           JAXUCZ010000010.1  102087947-102088059 c
            1316-1554           JAXUCZ010000010.1  102084391-102084629 c
            1555-1663           JAXUCZ010000010.1  102083745-102083853 c
            1664-1775           JAXUCZ010000010.1  102082137-102082248 c
            1776-1945           JAXUCZ010000010.1  102081610-102081779 c
            1946-2011           JAXUCZ010000010.1  102081306-102081371 c
            2012-2060           JAXUCZ010000010.1  102080342-102080390 c
            2061-2171           JAXUCZ010000010.1  102078724-102078834 c
            2172-4635           JAXUCZ010000010.1  102070842-102073305 c
FEATURES             Location/Qualifiers
     source          1..4635
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q32.1"
     gene            1..4635
                     /gene="Rnf157"
                     /note="ring finger protein 157"
                     /db_xref="GeneID:688272"
                     /db_xref="RGD:1591154"
     exon            1..338
                     /gene="Rnf157"
                     /inference="alignment:Splign:2.1.0"
     CDS             251..2296
                     /gene="Rnf157"
                     /EC_number="2.3.2.27"
                     /note="RING-type E3 ubiquitin transferase Rnf157"
                     /codon_start=1
                     /product="E3 ubiquitin ligase Rnf157"
                     /protein_id="NP_001406598.1"
                     /db_xref="GeneID:688272"
                     /db_xref="RGD:1591154"
                     /translation="MGALTSRQHAGVEEVDIPSNSVYRYPPKSGSYFASHFIMGGEKF
                     DCTHPEGYLFGENSDLNFLGNRPVSFPYAAPPPHEPVKTLRSLINIRKDTLRLVKCAE
                     EVKSHGEEAGKAKVHYNVEFTFDTDARVAITIYYQATEEFQNGIASYIPKDNSLQSET
                     VHYKRGVCQQFCLPSHTVDPSEWAEEELGFDLDREVYPLVVHAVVDEGDEYFGHCHVL
                     LGTFEKHSDGTFCVKPLKQKQVVDGVSYLLQEIYGIENKYNTQDSKVAEDDVSDNSAE
                     CVVCLSDVRDTLILPCRHLCLCNTCADTLRYQANNCPICRLPFRALLQIRAMRKKLGP
                     LSPSSFNPIISSQTSDSEEHSSSENIPAGYEVVSLLEALNGPLTSSPAVPPLHVLGDG
                     HLSGMLPSYGSDGHLPPVRTLSPLDHLSDCNSQGLKLNKSLSKSISQNSSVLHEEEDE
                     RSCSESDTQLSQRLSAQHPEEGPDVTPESENLTLSSSGAVDQSSCTGTPLSSTISSPE
                     DPASSSLAQSVMSMASSQISTDTVSSMSGSYIAPGTEEEGEAPPSPRAASRAPSEEEE
                     TPAESPDSNFAGLPAGEQDAEGNDIMEEEDRSPVQEDGQRTCAFLGMECDNNNDFDVA
                     SVKALDNKLCSEVCLPGTWQHDAAIINRHNTQRRRLSPSSLEDPEEDRPCVWDPLAV"
     exon            339..457
                     /gene="Rnf157"
                     /inference="alignment:Splign:2.1.0"
     exon            458..546
                     /gene="Rnf157"
                     /inference="alignment:Splign:2.1.0"
     exon            547..693
                     /gene="Rnf157"
                     /inference="alignment:Splign:2.1.0"
     exon            694..811
                     /gene="Rnf157"
                     /inference="alignment:Splign:2.1.0"
     exon            812..878
                     /gene="Rnf157"
                     /inference="alignment:Splign:2.1.0"
     exon            879..922
                     /gene="Rnf157"
                     /inference="alignment:Splign:2.1.0"
     exon            923..970
                     /gene="Rnf157"
                     /inference="alignment:Splign:2.1.0"
     exon            971..1042
                     /gene="Rnf157"
                     /inference="alignment:Splign:2.1.0"
     exon            1043..1202
                     /gene="Rnf157"
                     /inference="alignment:Splign:2.1.0"
     exon            1203..1315
                     /gene="Rnf157"
                     /inference="alignment:Splign:2.1.0"
     exon            1316..1554
                     /gene="Rnf157"
                     /inference="alignment:Splign:2.1.0"
     exon            1555..1663
                     /gene="Rnf157"
                     /inference="alignment:Splign:2.1.0"
     exon            1664..1775
                     /gene="Rnf157"
                     /inference="alignment:Splign:2.1.0"
     exon            1776..1945
                     /gene="Rnf157"
                     /inference="alignment:Splign:2.1.0"
     exon            1946..2011
                     /gene="Rnf157"
                     /inference="alignment:Splign:2.1.0"
     exon            2012..2060
                     /gene="Rnf157"
                     /inference="alignment:Splign:2.1.0"
     exon            2061..2171
                     /gene="Rnf157"
                     /inference="alignment:Splign:2.1.0"
     exon            2172..4635
                     /gene="Rnf157"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atcacgcggt ctgaggcggc ggcgcccccc ggctcagccc cgcagccccc tcaggcagag
       61 gcgccgccgc ggtgtccggc ggaggatggt gcgcaccgtg cgggccgctc cccgcagcct
      121 cagccgcagc agcgcctcag ccgagcgggc cgcggcggac agccgacccc cgcaccgggc
      181 gtgcgacggg ccggcgcgct gaggctcgga cgccagagcc cgggcgacgc cgcgatccct
      241 cgcagcggcc atgggggccc tgacgagccg gcagcacgcg ggcgtggagg aggtggacat
      301 cccgtccaat tccgtgtacc gctacccgcc caagtccggc agctattttg ccagccactt
      361 catcatggga ggagagaagt ttgactgcac acatccggag ggctacctgt ttggcgagaa
      421 cagcgacttg aacttcctgg gaaacaggcc agtctcgttt ccttatgctg ccccacctcc
      481 ccacgaacct gtgaagactc tgagaagcct gatcaacatc cggaaggaca cgctgagact
      541 tgtcaaatgt gctgaggaag tgaagagcca cggagaagag gcgggcaaag cgaaggtcca
      601 ctacaacgtc gagttcacct ttgacacaga tgcccgggta gccatcacca tctactatca
      661 ggccactgag gaattccaga acggcattgc cagctacatc ccaaaagaca acagcctgca
      721 gtcagaaacc gtgcactaca agcgaggggt gtgccagcag ttttgcctgc cctcccatac
      781 ggtggacccc tcagagtggg ctgaagagga gcttggcttt gatctggacc gagaggtcta
      841 ccctttggta gtgcatgctg tggtggatga aggagatgaa tattttggcc actgccatgt
      901 gcttctgggc acctttgaga agcactcaga cgggaccttc tgtgtcaagc ccctcaagca
      961 gaagcaagtg gtggatggcg tcagctacct tcttcaggag atctacggga ttgaaaacaa
     1021 gtacaacaca caagattcca aggtggcaga ggatgatgtc agtgacaaca gtgcggagtg
     1081 tgtggtgtgt ctctcagacg tccgtgacac tttgatcctg ccctgccggc acctgtgcct
     1141 ctgcaacacc tgtgcagaca ccctgcgcta ccaggccaac aactgcccca tctgccggct
     1201 gcccttccgg gcactgcttc agatccgagc catgaggaaa aaattgggcc ctctgtctcc
     1261 aagcagcttt aaccccatca tctcttccca gacttcggac tctgaggaac attcatcctc
     1321 agagaacatc cctgcgggct atgaagtggt gtctctcctg gaggccctca atgggcccct
     1381 cacctcatcc ccagcggtgc ctccccttca cgttcttgga gatggccacc tctcaggaat
     1441 gctgccgtcc tatggcagtg atggccacct gccccctgtt aggacactgt ccccccttga
     1501 ccacctgtct gattgcaaca gccaagggct caaactcaac aagtctctct ccaagtccat
     1561 ttcccagaat tcttctgtgc ttcacgaaga ggaagatgag cgctcttgca gtgagtcaga
     1621 cactcagctc tctcagaggc tgtcagccca gcatcctgaa gagggacctg atgtgactcc
     1681 agagagtgag aacctcacgc tgtcctcctc aggggctgtt gaccagtcat cttgcacagg
     1741 gactccgctc tcttccacca tctcctcccc agaagaccca gccagcagca gcctggccca
     1801 gtcagtcatg tccatggcct cctcccagat cagcactgac accgtgtcct ccatgtctgg
     1861 ctcctacatt gcacctggca cagaagaaga aggagaggcc ccaccttccc cccgagctgc
     1921 tagcagggcc ccttcagaag aggaggagac cccagcagag tccccagaca gcaattttgc
     1981 tggccttcca gctggagagc aggatgcaga gggaaatgat atcatggagg aagaggacag
     2041 atcccctgtg caagaagatg gccagaggac atgcgcattt ctaggcatgg agtgtgacaa
     2101 taacaatgac tttgacgtcg cgagcgtgaa agcactggac aataagctgt gctctgaggt
     2161 ctgcttaccc ggtacctggc aacatgatgc cgccattatc aaccgtcaca atacccagcg
     2221 ccggcgacta tcacccagca gcctggagga ccctgaggag gacaggcctt gcgtatggga
     2281 tcctttggct gtctgagggc actggcacct gtacctgggc ttcccctcct gtccgccttc
     2341 catctgtcct cactggacca caggccttct gggcatcttc aacaagacac gtggactttc
     2401 tactctcatg aagggaggac agtgcaaccc tccaccaact tcatctcctg taaccatgat
     2461 tcttaccctc tcagaaagta ccagaagcct tcctcctgtg ggctgatgtg tgccagccaa
     2521 acccagtggg tcagctgagc tgagggtcag ggctggttgt ttctgtagcc ttttctcttc
     2581 caaatggaga ccaacgagac tgaagagttt ggcagctttg ttagacaccc atggacaggt
     2641 ttttgtttct ggcacctcat aagcaattag aaacctaact caaagcggtc aggaactggc
     2701 tccatgaggg acaccatcca cacctgcctc ccagaacacc gggagctcct tactcgagcc
     2761 taagggattg gtagcagctg aagtgttggt tgggagccag atctactcag agttggtctc
     2821 ctgcacctcc tgtgccacgg ttaggaagat cacccttgca aggcctgtcc tcaggtgcag
     2881 tcaggaaggg ctgctgggtc acctccatgc agcgccaggg ctggctcttc acataccttc
     2941 actgcagcca ctgaggggga ggcccaaacc cagctaagcg cttcgctgcc cacttcgtaa
     3001 gagctgaaga acgaggctaa gagctgatgc ccagtggttc tcaaactgct gcgcaggaca
     3061 ccaaaggaat ggcaaaggct ctggaccaga ggcttagaag acctccctac cctagtgtac
     3121 tcctcccctg cctttcagat cggagatgag aggtgcggac tctccatggg ttcaccagtg
     3181 ctgagagatg ccatccagtc agcactcaaa gccacagccg caaactggca ggaaattgtt
     3241 gggtgtcaca cctttctcag ttcagtgggt tttacatggc tctaaaggag atagatgcct
     3301 gtccactggt cttttgggac agggaattag ttgttcaggg gaacatgaga tgtttgggaa
     3361 tcaagattag tgacaggtac ctagggtgag ataccaggag ctttagactt ggctagtgtg
     3421 gtcctggaaa ggctttcccc caaacgcctg tgcccaggac cctgagggga gatggggttg
     3481 gagagcacgg tctcaaacct gctatgtagc tgaggatgac cttgaacttc tgatttccct
     3541 gcctggattg cccaagcatt agaattccaa gcctgcacca ctatacagct ctcctttatg
     3601 tggcaatcac actgctaggg ggaaatctgc tgtgctgccc aagtgtgata ggctgagctt
     3661 gagatcccat cgcccgttca aaggctacat cctatttttt acttgcccaa cattccagta
     3721 gcccctatca cacttaagac tcacaccagt gtacgctgag caatacctac atttcctcaa
     3781 agccgggagc agaagcaacg gggaagttcc cttagcctgg gatggtggca catagagctg
     3841 cctcctcccc tcgagggcag taggaaggcg gtattcagtg tgtggtgtga cccgggagga
     3901 gtggtggaag aagctgagat gaagaagacg caggtaaaca gtggccaggg accctcaaaa
     3961 aagccattat aatcagccct tccctctgcc acacaagtgt tccgcccgaa ttcattccat
     4021 aatcccggca cccgggttag agtacccttt gctctgcctt gcacagctct gccccctcac
     4081 tctgtccttt tacttcttgg cgagcagaaa tagcccattc tcggggtgga tccccatcag
     4141 ctgacacact ctacccagtc catttggaaa cagttccttt gtcagggtcc aagcgaaagg
     4201 gcaagcacgt tctcttggtg cctttggctc ctcaccacac cacacctttc tatacgtggt
     4261 actgtagtga tctcagtctc ctcaaggagc cttttgcttt acctaatttc atcccaccag
     4321 agtttttacc tgctgtggca tctgccgggc acaaacctga acactaagcc atctcactgg
     4381 ggagctagtc ctgtccacct ggtgttggct gctggttgct cactttgttt tagggcctgc
     4441 acacctgggg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgccatct gtgtacccct
     4501 cacactccct ggagtacact tgtgggcaca ttacagtggg gacatcaaga tgcaatattt
     4561 atggattgct gcatgattct taaaattaaa taaaactgtt tacaggggca ggggagccgt
     4621 taactacaaa gtgaa
//
