LOCUS       NM_001106305            5489 bp    mRNA    linear   ROD 17-FEB-2024
DEFINITION  Rattus norvegicus ring finger protein 152 (Rnf152), mRNA.
ACCESSION   NM_001106305 XM_001063123 XM_219409
VERSION     NM_001106305.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5489)
  AUTHORS   Deng,L., Jiang,C., Chen,L., Jin,J., Wei,J., Zhao,L., Chen,M.,
            Pan,W., Xu,Y., Chu,H., Wang,X., Ge,X., Li,D., Liao,L., Liu,M.,
            Li,L. and Wang,P.
  TITLE     The ubiquitination of rag A GTPase by RNF152 negatively regulates
            mTORC1 activation
  JOURNAL   Mol Cell 58 (5), 804-818 (2015)
   PUBMED   25936802
REFERENCE   2  (bases 1 to 5489)
  AUTHORS   Zhang,S., Wu,W., Wu,Y., Zheng,J., Suo,T., Tang,H. and Tang,J.
  TITLE     RNF152, a novel lysosome localized E3 ligase with pro-apoptotic
            activities
  JOURNAL   Protein Cell 1 (7), 656-663 (2010)
   PUBMED   21203937
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JACYVU010000242.1.
            
            [WARNING] On Mar 29, 2024 this sequence was replaced by
            NM_001106305.3.
            
            On Nov 27, 2020 this sequence version replaced NM_001106305.1.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-329               JACYVU010000242.1  7764042-7764370     c
            330-451             JACYVU010000242.1  7762771-7762892     c
            452-5489            JACYVU010000242.1  7688120-7693157     c
FEATURES             Location/Qualifiers
     source          1..5489
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13p11"
     gene            1..5489
                     /gene="Rnf152"
                     /note="ring finger protein 152"
                     /db_xref="GeneID:293561"
                     /db_xref="RGD:1305251"
     exon            1..329
                     /gene="Rnf152"
                     /inference="alignment:Splign:2.1.0"
     exon            330..451
                     /gene="Rnf152"
                     /inference="alignment:Splign:2.1.0"
     exon            452..5489
                     /gene="Rnf152"
                     /inference="alignment:Splign:2.1.0"
     CDS             594..1205
                     /gene="Rnf152"
                     /EC_number="2.3.2.27"
                     /note="RING-type E3 ubiquitin transferase RNF152"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase RNF152"
                     /protein_id="NP_001099775.1"
                     /db_xref="GeneID:293561"
                     /db_xref="RGD:1305251"
                     /translation="METLSQDSLLECQICFNYYSPRRRPKLLDCKHTCCSVCLQQMRT
                     SQKDVRCPWCRGITKLPPGFSVSQLPDDPEVLAVIAIPHTSEHTPVFIKLPSNGCYML
                     PLPISKERTLLPGDMGCRLLPGSQQKSLTVVTIPAEQQPLQGGAPQEAVEEEPDRRGV
                     AKSSTWSGVCTVILVACVLVFLLGIVLHNMSCISKRFTVISCG"
ORIGIN      
        1 cagtgcttgg gtctctgggg gtggcaccaa aagctcccgc tcagtgtccg gcgcctggcg
       61 gcgggtgtcc gagcgtggac tcggagggca gccaggcagg tggagggcgc cgcctgaagc
      121 agaaggaggg acgagctggg agctgggctg cgggaggcgc tgccgccact ctgcccgcgc
      181 tgccccgcaa cccgcggcgg gaggagcagg cagcagccgg ccctgggcgc tcgtctagca
      241 gagcgcggtg ggcagcgtgg accctcggga tgctgcccac gttcctgcag ccgcccgcgg
      301 cgtagcagag ccggggccac tgctgagagg ctgaacaaag ctggtctcaa tcgcgcttcc
      361 tgcttgtcag cctcttgcct cccaaatgct tactgtttcc acttgatgtc atcacataga
      421 agggggtaaa agggacgcgt gacagattca gaaattagca cgtgtgcgaa tgccagatgc
      481 cctgtgagct tgccattccc tgttgacctt gagaagacga atccagagcg gtgacctttg
      541 agaaccagct ttccaccttc ctgttggccc cgccatttgg ctcttggtcc aagatggaga
      601 cgctctccca ggattccctg ctggaatgtc agatatgttt taattattac agcccccgac
      661 gaaggcccaa gttgctggat tgcaagcaca cctgctgctc agtgtgcctc cagcagatga
      721 ggaccagcca gaaggacgta aggtgtccct ggtgccgtgg catcaccaag ttgcccccgg
      781 gcttctctgt atcacagctg cccgatgatc ctgaggtctt ggcggtcatc gccataccac
      841 acacttccga gcacacccca gtcttcatca aacttccaag caatgggtgc tacatgctgc
      901 ccctgcccat ctctaaagag cgtacactcc tgccgggaga catgggctgc cgcctgctgc
      961 cagggagcca gcagaagtct ctcactgtgg tgaccatccc tgcagagcag cagcccctgc
     1021 agggtggagc tccccaggag gccgtggagg aggagcctga cagacggggc gtggcgaaga
     1081 gttccacgtg gtctggcgtg tgcactgtca tcctggtggc ctgtgtgttg gtcttccttc
     1141 tgggcattgt gctacacaac atgtcctgca tctctaagcg tttcactgtt atatcctgtg
     1201 gttgaagcct ttcccaggga aggcctcttg cgggtgccaa cttagggggt gagcaagtgt
     1261 tgatgatggg atccctgtga taagatgggg atgatattga gcatttggtg caagcgctgg
     1321 cctgcgttga ttcgcctaaa gacaagggcg gagggtgagg tctcagcaag atcccaggcg
     1381 aagagtttag agatggtgac agctgtgaag atgtttgcat gcttgtgaat ccaatgggct
     1441 gtaatttacg attttccaaa atcctggtcc caagttagac ttttctactt agacatgaaa
     1501 ctgtacatgt gggtgcaata gctctctaaa tacggtagat ggtaggttaa aacagatgct
     1561 gtgtacacaa gtagaattaa acctcaaatc cgtgtttaaa aaacaaaaac aaaaacagtg
     1621 aagacccaga gctggctccc gtgtgtgcat gtttgtgagt gtgctcacac gtgttcatgc
     1681 gtgggctgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgat tgaactctgg
     1741 tcttcataaa ctttttatat attttgaatg gcacccaaat caaaataatc aaaacagact
     1801 ttttgactgt ttgaagaaaa tgtttgcaca catgtctcca gtgtgttgtg ctttgtcaag
     1861 ttccttcatt tttcttcatc tgtgatttaa gcttgctatg tgcttgttaa gctggaagcc
     1921 caacaggcga gtgatggaca gggaaatatg gcaatgccga attccccagg aaacctatat
     1981 gccaatcttt ctcaagccat ctcacaagac aagaatttaa aatgtaaata ttgtgaacct
     2041 ctgtgtgtgt tttgtgtgtg taattcgatt tatctcaggt ttttgatttt tttttcctga
     2101 agaatcctgg gagtaagact ttgtggacat gtataagcca agtgtctaaa ataccagcct
     2161 cctggccgga gcctgggtct ttctggattc cctatacaat cacctccagc atccacttgc
     2221 cgctttgttg tgtgtagtga tcccatgcca gtaaaggctc ggacagagag cctcagaaga
     2281 acgtgtcatt tttccctcag tttggagggc tttgtgtgaa agtcacaagt gttgttcatc
     2341 aatggcacac ctagatgggc attgtaatag acagtccttg ataatctttt ctttgaaaga
     2401 tttccctgta agagttaatc tgcttagaat tcaatttcat cttgttggaa ccagcaagaa
     2461 aatgttttgt atttcaaatg tttctactgc caacagtagt atggcgaaca aaaatgtatg
     2521 ttctctatgt aagtgaacca gtttttcctg agtgctcaac tatttttaaa tgtgaattca
     2581 tgaagagagt tctgttagca tgacaggagc agtctctgtc cctggctgtg tgtgcactgg
     2641 gaaagagctg tgagtgctat cgtcctcttt gaactctgtg gaatgagtga ggtttgtcaa
     2701 ggactccact cagctgtgtt cctctctgct gttctgttga atccctgaaa tggtgggaag
     2761 gacgggaaag gcaaaggaaa ggaaacagtg gcactggctg gacaaagcca ggtcagaaac
     2821 agtcctggaa catggaggca atgctagcct tcatcttcaa gctgcgcaac agacaaagtg
     2881 atggctttgc agtgaaataa aacaaaggaa taacatctag agcacaaagc taacaattgg
     2941 catgaaaatt caacatcgaa ttatgagctc tggtttttaa aaatctttca aatttgtaag
     3001 gcctttagaa aaaaaatgta tctgagggct caaactagaa attaggttaa aataccgttt
     3061 tattgtgtaa gctattgggc attatacaac aaataatcta ggatttattt ggtattaata
     3121 atttaggtat cattagctga atactatcct ctattatgta acgtaatata ttgttgggtt
     3181 agtgtcaatt tctcaaactc tcaggctgct ctaatgcatg tctgacccac tttgtgtgtc
     3241 tctcagagtc aaaaacacac atagacagaa atgtcgcata aaggatgtta tgtttccaat
     3301 ggatgctact cttgcaaatt taagccaggc catatttaaa ttcatctggg agggatatca
     3361 gcataccttt ctgtacagta gaaaacgact gatcccatag tgcagtgtgt aaacgcgttc
     3421 tagttatcta ggaggcaatt tatagatact aacgtgtgtt gatatggtgt cctgtggttt
     3481 ttattgcaaa gctgtatagt aaaattgtcc acagaactct tacttaaaaa gtccatgtta
     3541 gagctgtaat taagcaaact cagtctgctc cctggtagac tctcaacctc acaacctgac
     3601 agtaacaacc caagtcaaag cttttatatg tgtgcttgat ctaagaaaca ttatttaact
     3661 gttgaaatgg attctgccta gggtttgcat atgtgcttat tggggtgtgt gtgtgtgtgt
     3721 gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gctcgcacgc aaggaggact gccaatttct
     3781 atatacttga tgttttagtt tcttctggaa tttacccaaa acactaaaaa tttatctacc
     3841 ccatgtggca caagcagcag gtcttagagt cacatgccag tggcaggtcc agcagttatc
     3901 tctgaaagga gcctttactg gcttcatctt gagatgagct catgggcgtg tgtagagagc
     3961 agtagtgtgc aggttgtaat gctatagcta gaagacaaga cctgtgtcct gctgtgccct
     4021 attagtcctc cctaggcttg ccaccttccc tgtcaggcta tgacccagta caggctctgg
     4081 agatgccctt tgctgtgtca gctattgctt taagggttgt ttcagagatt aatttctttc
     4141 tagatagctt ccttttgggg aagaaaaggg gggttggttt agggatgaat atagatatta
     4201 aaagaaaact ttcaaaccat tgtgatccga atatttagaa gtgcaaaaca tcagccagga
     4261 tgctgtcccc catatgtcaa ggatgataag tgttgtgtaa atagtgacct ataagaagca
     4321 tgacgttctt ctttattaat gatcttgaca tagcaaggga atgcttactg tgttaagtag
     4381 agccaagtat ggcacttcat gtgttgtctt tagaaaattt ttgtacaatg acctggtata
     4441 taaattgtaa tgacaaaggc aaattacttc tgaatttcag tcacacctta ttatcaggaa
     4501 gatctaaggc tttaaaaaaa tagaattaaa tttcatgctc tgcatgactc acagagtggg
     4561 tctgttggag tgtcagcttt gtgttagtta gttcagctct tggaattctc taggtcagtc
     4621 ctgcttgata gaactttttt gagttgacgg aaaccgttct gtaattgttc cgtgttgttt
     4681 agtagagtgg ccactaagcc acgtggctgt taagcaatta attggggatg actgaagaag
     4741 tgacttttaa atggtattta attttaagta atttaaagtt aaatattcct ctgtggcttg
     4801 tgaccacact ggccataatg acattaggaa gttaacaaag tgacaggaag gccaagagag
     4861 tttgttgact agtatcagtt ggccaaaaga aattcctttc tagcttaaag aagtttatga
     4921 gctccaatgg ggagggtggc agtaaaatct catccgttgc cctttggggt tattgcttag
     4981 atactttgga tcaagcaatg agcagttaag cttaaagaga actttattaa gcaagcccct
     5041 tttctgggac cattagctgc atgaagctca tagctagaca gtagctgtaa aatttttgac
     5101 ttgcaagcta tgcatgacct gtgctgtgaa actgtatgta gggtcctgtg gccaaaaaat
     5161 gagtcaatgt tacagaaaat caaataaata agagtctgat gaaatccccg ttcacttttg
     5221 atctctttcc cgactgcatc actgcatcag tgaggtggga aatccaagat caagcatgct
     5281 ttgcagtgtt tacagtgttt ctatttgccc ttgaagtcag cctgtttgtg tgtgtatttg
     5341 gtgtgggcat atatggatgg caggctagaa cagaggcact acttttagag tgagatgtga
     5401 cattgttaag tgtctctctt tttaaattta gttatcatta aaaggtttga aactttgcac
     5461 aaaggcactt tttacatttt catagttta
//
