LOCUS       NM_001109444            2241 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ring finger protein 13 (Rnf13), mRNA.
ACCESSION   NM_001109444 XM_001057588 XM_001057631 XM_001057755 XM_001057819
            XM_001057871 XM_006232391
VERSION     NM_001109444.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2241)
  AUTHORS   Arshad,M., Ye,Z., Gu,X., Wong,C.K., Liu,Y., Li,D., Zhou,L.,
            Zhang,Y., Bay,W.P., Yu,V.C. and Li,P.
  TITLE     RNF13, a RING finger protein, mediates endoplasmic reticulum
            stress-induced apoptosis through the inositol-requiring enzyme
            (IRE1alpha)/c-Jun NH2-terminal kinase pathway
  JOURNAL   J Biol Chem 288 (12), 8726-8736 (2013)
   PUBMED   23378536
REFERENCE   2  (bases 1 to 2241)
  AUTHORS   Bocock,J.P., Carmicle,S., Chhotani,S., Ruffolo,M.R., Chu,H. and
            Erickson,A.H.
  TITLE     The PA-TM-RING protein RING finger protein 13 is an endosomal
            integral membrane E3 ubiquitin ligase whose RING finger domain is
            released to the cytoplasm by proteolysis
  JOURNAL   FEBS J 276 (7), 1860-1877 (2009)
   PUBMED   19292867
REFERENCE   3  (bases 1 to 2241)
  AUTHORS   Schroder,B., Wrocklage,C., Pan,C., Jager,R., Kosters,B.,
            Schafer,H., Elsasser,H.P., Mann,M. and Hasilik,A.
  TITLE     Integral and associated lysosomal membrane proteins
  JOURNAL   Traffic 8 (12), 1676-1686 (2007)
   PUBMED   17897319
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC081881.1.
            
            On or before Dec 15, 2013 this sequence version replaced
            XM_006232391.1, NM_001109444.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC081881.1, SRR8487230.147215.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2241
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q26"
     gene            1..2241
                     /gene="Rnf13"
                     /note="ring finger protein 13"
                     /db_xref="GeneID:681578"
                     /db_xref="RGD:1594062"
     exon            1..72
                     /gene="Rnf13"
                     /inference="alignment:Splign:2.1.0"
     exon            73..198
                     /gene="Rnf13"
                     /inference="alignment:Splign:2.1.0"
     CDS             85..1227
                     /gene="Rnf13"
                     /EC_number="2.3.2.27"
                     /note="E3 ubiquitin-protein ligase RNF13; RING-type E3
                     ubiquitin transferase RNF13"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase RNF13 precursor"
                     /protein_id="NP_001102914.1"
                     /db_xref="GeneID:681578"
                     /db_xref="RGD:1594062"
                     /translation="MLLSIGMLMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENA
                     SQTFEDLPARFGYRLPAEGLKGFLINSKPENACEPIVPPPLKDNSSGTFIVLIRRLDC
                     NFDIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIDILKKIDIPSVFIGESSANSLKD
                     EFTYEKGGHVILVPELSLPLEYYLIPFLIIVGICLILIVIFMITKFVQDRHRNRRNRL
                     RKDQLKKLPVHKFKKGDEYDVCAICLEEYEDGDKLRILPCSHAYHCKCVDPWLTKTKK
                     TCPVCKQKVVPSQGDSDSDTDSSQEENQVSEHTPLLPPSASARTQSFGSLSESHSHHM
                     TESSDYEDDDNEETDSSDADNEITDHSVVVQLQPNGEPDYNIANTV"
     exon            199..279
                     /gene="Rnf13"
                     /inference="alignment:Splign:2.1.0"
     exon            280..405
                     /gene="Rnf13"
                     /inference="alignment:Splign:2.1.0"
     exon            406..493
                     /gene="Rnf13"
                     /inference="alignment:Splign:2.1.0"
     exon            494..584
                     /gene="Rnf13"
                     /inference="alignment:Splign:2.1.0"
     exon            585..690
                     /gene="Rnf13"
                     /inference="alignment:Splign:2.1.0"
     exon            691..784
                     /gene="Rnf13"
                     /inference="alignment:Splign:2.1.0"
     exon            785..865
                     /gene="Rnf13"
                     /inference="alignment:Splign:2.1.0"
     exon            866..2214
                     /gene="Rnf13"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctcagtcatg aagtccgggt agcgacttct cttgggtggc cgtgacccta ggttccgggg
       61 gccggacttc aggtgattca caagatgctg ctctccatag ggatgctcat gctgtccgcc
      121 acacaagtct ataccatctt gactgtgcaa ctctttgcat tcctgaacct gctgcccgta
      181 gaggcagaca ttttagcata taattttgaa aatgcatctc agacatttga ggaccttcca
      241 gcaagatttg gttatagact accagctgaa ggcttaaagg gttttctgat taactcgaaa
      301 ccagagaatg cttgtgaacc tatagtgcct ccaccactga aagacaattc atctggtact
      361 tttatcgtat tgattagaag acttgattgt aattttgata taaaggtttt aaatgcacag
      421 agagcaggat acaaagcagc catagttcac aatgtagact ctgatgacct gattagcatg
      481 ggatccaacg acattgatat attaaagaaa attgacattc catctgtctt tattggtgaa
      541 tcatcagcta attccctaaa agatgaattc acatatgaaa aagggggcca cgttatctta
      601 gttccagaac tgagccttcc tttggagtac tatctgatcc ccttcctcat catagtgggc
      661 atctgcctca tcttaatagt tatttttatg attacaaaat ttgttcagga cagacataga
      721 aatagaagaa acagacttcg caaagatcaa cttaaaaaac ttcctgtaca taaatttaaa
      781 aagggagatg agtacgacgt gtgtgctatt tgcttggagg aatatgaaga tggagataag
      841 ctcaggatcc ttccctgttc ccatgcttat cattgcaagt gtgtagatcc ctggctaact
      901 aaaaccaaaa agacctgtcc agtctgcaaa caaaaggttg tcccttccca aggtgactcg
      961 gactctgaca cagacagcag tcaggaggag aaccaagtgt cagagcacac ccctttactt
     1021 ccaccctcag cttctgccag gacccagtca tttgggtctc tatcagaatc ccactcacat
     1081 cacatgacag agtcttcaga ctacgaggac gacgacaatg aagagaccga cagcagtgat
     1141 gcagacaatg aaattactga ccacagtgtt gtggtccagc tgcagcctaa tggtgagccg
     1201 gattacaaca tagcaaatac tgtgtgactg actttcaggt ggttggttta tttcccttaa
     1261 aatgtttatt taggtatatg atttcatttt tttgctccct ttagaagttt ctatagaaat
     1321 aacttacttt tcagttttct agtgtaatca agtcctgaac caggctattt gatctctgat
     1381 acttatgtcc agtggtatcc agccactcta ctaaccagta acagactggt gctgtaactc
     1441 aggcatcact ttagctctgg ggatgacgag atgtagccag gacacttaca aatcctcagt
     1501 gtagcttgaa acgaagccct agatcacagt atgcagatgt cctcttacac acgaggtctg
     1561 ccaaggtcat ctagcatgag ctaaacaact ctccctttca taaagttgcc tcgtgctgtt
     1621 gggttggcac atgtcccttc tgacagtccc tcggtgtcat gatgaatgcg tggcaacagc
     1681 agtttatttc ccttcacagt accacagaga aactaaaaga tgtcaccttc ctttctattc
     1741 ccgagtagtt tttcctcata ggaaaggtct agtgtttgtt gacttcaagt gctttgtttt
     1801 aaggttttca aaaccactat agtgttatga gtttgattcc acaggaatgt ctctggacct
     1861 cactttccat atttcagtat acttttgtgt tgtgattaaa aaatgctgca tcaaaaaact
     1921 aaatttcagc acctgttaat actgagatct catacctctt cataaagagc atcttatgct
     1981 aactagccct gctgaaccat gtgcagagga aattgttcaa gtattggatt tgaaaataag
     2041 tgcttttgtt taatagacct aatgtattga ggcaatgtat tatgaaaagc gaaattatat
     2101 aacactgtaa ctatgtagaa aatatactta tataatcaga atgctaagac tttttatatg
     2161 gccttgtatg atgagagctt caatgttaat aaatgttttc cactttaaaa gccaaaaaaa
     2221 aaaaaaaaaa aaaaaaaaaa a
//
