LOCUS       NM_001108560            2251 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus ring finger protein 115 (Rnf115), mRNA.
ACCESSION   NM_001108560 XM_001063345 XM_006232975 XM_342300
VERSION     NM_001108560.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2251)
  AUTHORS   Smith,C.J., Berry,D.M. and McGlade,C.J.
  TITLE     The E3 ubiquitin ligases RNF126 and Rabring7 regulate endosomal
            sorting of the epidermal growth factor receptor
  JOURNAL   J Cell Sci 126 (Pt 6), 1366-1380 (2013)
   PUBMED   23418353
REFERENCE   2  (bases 1 to 2251)
  AUTHORS   Ebstein,F., Lange,N., Urban,S., Seifert,U., Kruger,E. and
            Kloetzel,P.M.
  TITLE     Maturation of human dendritic cells is accompanied by functional
            remodelling of the ubiquitin-proteasome system
  JOURNAL   Int J Biochem Cell Biol 41 (5), 1205-1215 (2009)
   PUBMED   19028597
REFERENCE   3  (bases 1 to 2251)
  AUTHORS   Amemiya,Y., Azmi,P. and Seth,A.
  TITLE     Autoubiquitination of BCA2 RING E3 ligase regulates its own
            stability and affects cell migration
  JOURNAL   Mol Cancer Res 6 (9), 1385-1396 (2008)
   PUBMED   18819927
REFERENCE   4  (bases 1 to 2251)
  AUTHORS   Burger,A.M., Gao,Y., Amemiya,Y., Kahn,H.J., Kitching,R., Yang,Y.,
            Sun,P., Narod,S.A., Hanna,W.M. and Seth,A.K.
  TITLE     A novel RING-type ubiquitin ligase breast cancer-associated gene 2
            correlates with outcome in invasive breast cancer
  JOURNAL   Cancer Res 65 (22), 10401-10412 (2005)
   PUBMED   16288031
REFERENCE   5  (bases 1 to 2251)
  AUTHORS   Mizuno,K., Kitamura,A. and Sasaki,T.
  TITLE     Rabring7, a novel Rab7 target protein with a RING finger motif
  JOURNAL   Mol Biol Cell 14 (9), 3741-3752 (2003)
   PUBMED   12972561
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On or before Mar 1, 2022 this sequence version replaced
            XM_006232975.2, NM_001108560.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643297.8664.1,
                                           SRR26643288.10786.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-309               JAXUCZ010000002.1  186951106-186951414
            310-368             JAXUCZ010000002.1  186987317-186987375
            369-426             JAXUCZ010000002.1  186991144-186991201
            427-638             JAXUCZ010000002.1  187007216-187007427
            639-710             JAXUCZ010000002.1  187011246-187011317
            711-783             JAXUCZ010000002.1  187012423-187012495
            784-877             JAXUCZ010000002.1  187013375-187013468
            878-993             JAXUCZ010000002.1  187016104-187016219
            994-2251            JAXUCZ010000002.1  187017416-187018673
FEATURES             Location/Qualifiers
     source          1..2251
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..2251
                     /gene="Rnf115"
                     /gene_synonym="Zfp364"
                     /note="ring finger protein 115"
                     /db_xref="GeneID:362002"
                     /db_xref="RGD:1305315"
     exon            1..309
                     /gene="Rnf115"
                     /gene_synonym="Zfp364"
                     /inference="alignment:Splign:2.1.0"
     CDS             208..1125
                     /gene="Rnf115"
                     /gene_synonym="Zfp364"
                     /EC_number="2.3.2.27"
                     /note="zinc finger protein 364"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase RNF115"
                     /protein_id="NP_001102030.2"
                     /db_xref="GeneID:362002"
                     /db_xref="RGD:1305315"
                     /translation="MAEASAAGADAGSAVAAHRFFCHFCKGEVNPKLPEYICPRCESG
                     FIEEVTDDSSFLGGGGSRTDNSTATHFAELWDHLDHTMFLQDFRPFLSSNPLDQDNRA
                     NERGHQTHTDFWGPSRPPRLPMTRRYRSRGSTRPDRSPAIEGIIQQIFAGFFANSAIP
                     GSPHPFSWSGMLHSNPGDYAWGQTGLDAIVTQLLGQLENTGPPPADKEKITSLPTVTV
                     TQEQVNTGLECPVCKEDYTVEEKVRQLPCNHFFHSSCIVPWLELHDTCPVCRKSLNGE
                     DSTRQTQSSEASASNRFSNDSQLHDRWTF"
     exon            310..368
                     /gene="Rnf115"
                     /gene_synonym="Zfp364"
                     /inference="alignment:Splign:2.1.0"
     exon            369..426
                     /gene="Rnf115"
                     /gene_synonym="Zfp364"
                     /inference="alignment:Splign:2.1.0"
     exon            427..638
                     /gene="Rnf115"
                     /gene_synonym="Zfp364"
                     /inference="alignment:Splign:2.1.0"
     exon            639..710
                     /gene="Rnf115"
                     /gene_synonym="Zfp364"
                     /inference="alignment:Splign:2.1.0"
     exon            711..783
                     /gene="Rnf115"
                     /gene_synonym="Zfp364"
                     /inference="alignment:Splign:2.1.0"
     exon            784..877
                     /gene="Rnf115"
                     /gene_synonym="Zfp364"
                     /inference="alignment:Splign:2.1.0"
     exon            878..993
                     /gene="Rnf115"
                     /gene_synonym="Zfp364"
                     /inference="alignment:Splign:2.1.0"
     exon            994..2251
                     /gene="Rnf115"
                     /gene_synonym="Zfp364"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaggcgggc ctcgggtcgc gcggccgctg gcgggcgggc ctctcggggc cgggcggact
       61 cacgtgaccc ttgcgggcct tggagcggcg ggccgcccag aggaggcggc gacggcggcg
      121 gcggcggcgg cgaccgcagc ccaggaggta gcggcctggg gagggaccgc cggccgccct
      181 ttcggacatc ctccgcagag gcgaaaaatg gcggaggcct cggcggcggg ggcggacgcg
      241 ggctccgctg tcgccgcgca ccgtttcttc tgccactttt gtaagggcga ggtcaatccc
      301 aaactaccgg aatatatatg tcccagatgt gaatcaggct ttattgagga agtgacagat
      361 gattccagtt tcttaggtgg tggtggaagc cggacagaca atagcacagc aacacatttt
      421 gccgagctct gggaccatct ggatcacaca atgtttttac aagattttag accatttcta
      481 agtagcaatc ctctggacca agataataga gccaatgaga gaggtcacca aactcacact
      541 gacttttggg gaccaagtcg gcctccaagg ttgcctatga caagaagata caggtctcga
      601 ggaagcactc gtcctgacag gtcgccagct atcgaaggaa taatacaaca gatctttgca
      661 ggattctttg caaattctgc cattcctggg tccccacacc ccttttcttg gagcgggatg
      721 ctgcactcca accctgggga ctatgcctgg ggtcagacag ggcttgatgc cattgtaacc
      781 cagcttctag gacagctgga aaacacaggg ccccctccag ctgacaagga gaagatcacg
      841 tctctgccaa cagtgacagt aactcaggag caagtcaata cgggtttaga atgtccagta
      901 tgtaaagaag attacacagt tgaggagaaa gtccggcagt taccctgcaa ccacttcttt
      961 cacagcagct gcatcgtgcc ctggttagaa ctgcatgaca catgtccagt atgtaggaag
     1021 agcttaaatg gtgaggactc gactcggcaa acccagagct ccgaggcctc tgcaagcaac
     1081 aggtttagca atgacagcca gctacacgac cgatggactt tctgaaacta aagaccacac
     1141 ccgaaccagg gctgcctgtg ttagtcctgt tgtcatagct gtaaattgta tcaaaactaa
     1201 acaaacaaaa tagtagatgg atttaggaat catgtaagag actcaaaccc ataatattaa
     1261 tgcaatgagt gtatttcttc tctaaattta aagttagggc ttacagatgg aatcgtattg
     1321 acaaccaaat gcctcttgtt cctgaattga gtgatagttt tctaagtgtg aaacttaatt
     1381 atgtcagttt gctcctgcct gagtagaatc aattccgtaa agtctaggta ggttctgctg
     1441 tcatgttgtc tagtaatgga tggctctacc tcctcctcct gtctctgtcc taccattagt
     1501 ggatttcaca gcaaatacag acaagccaga gccctcaggt cctgtcatat aaagcctttt
     1561 ttcttaattg tacaagagta caagtacaca cttcaggaat ctgagactct aatgctgtct
     1621 tgtcttgatc atcagagagc aattccagtg ggaaggagaa acgacggcct gcactgtcca
     1681 cgtgggcttt cttattttag ttcaggaagt acagtttccc taaaaaccac catggcatgt
     1741 cttagttttg ggttggtaga aatctgattt tggtttctct gtgacattag attgagcagc
     1801 atatagatgt ggaaagacag atgtgggaga ctttactact gcgatatttt ttaatgaccc
     1861 tcaactcatt gtttattgtc tttcatacta ggaaccttat aataattttc ttcataaaat
     1921 taatttcctt caaaaataca ataaattcct tcataaaaaa taggattatt ttattactgt
     1981 ttctatacca gttcacagtt ctggtaattc attgttattt aggaattaac attgtgtgtt
     2041 gtcttgtttt agtttgtaca gcccattttt catgtctgaa actttgcctg ttctgttcag
     2101 ttctagctgt acttggaatc aatctgatca atgtaatcat gcccaaaaca acttagtttg
     2161 ggaaaggtaa accttgtttt aaattctaac aatgctcata cgcatactct gtacatgttt
     2221 acaatggaat aaatggagat tgtggagcat g
//
