LOCUS       NM_138613               2923 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ring finger protein 112 (Rnf112), mRNA.
ACCESSION   NM_138613
VERSION     NM_138613.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2923)
  AUTHORS   Lee,K.H., Chen,C.L., Lee,Y.C., Kao,T.J., Chen,K.Y., Fang,C.Y.,
            Chang,W.C., Chiang,Y.H. and Huang,C.C.
  TITLE     Znf179 induces differentiation and growth arrest of human primary
            glioblastoma multiforme in a p53-dependent cell cycle pathway
  JOURNAL   Sci Rep 7 (1), 4787 (2017)
   PUBMED   28684796
  REMARK    Erratum:[Sci Rep. 2018 Sep 3;8(1):13375. PMID: 30177766]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2923)
  AUTHORS   Chuang,J.Y., Kao,T.J., Lin,S.H., Wu,A.C., Lee,P.T., Su,T.P.,
            Yeh,S.H., Lee,Y.C., Wu,C.C. and Chang,W.C.
  TITLE     Specificity protein 1-zinc finger protein 179 pathway is involved
            in the attenuation of oxidative stress following brain injury
  JOURNAL   Redox Biol 11, 135-143 (2017)
   PUBMED   27918959
REFERENCE   3  (bases 1 to 2923)
  AUTHORS   Tsou,J.H., Yang,Y.C., Pao,P.C., Lin,H.C., Huang,N.K., Lin,S.T.,
            Hsu,K.S., Yeh,C.M., Lee,K.H., Kuo,C.J., Yang,D.M., Lin,J.H.,
            Chang,W.C. and Lee,Y.C.
  TITLE     Important Roles of Ring Finger Protein 112 in Embryonic Vascular
            Development and Brain Functions
  JOURNAL   Mol Neurobiol 54 (3), 2286-2300 (2017)
   PUBMED   26951452
REFERENCE   4  (bases 1 to 2923)
  AUTHORS   Su,T.C., Lin,S.H., Lee,P.T., Yeh,S.H., Hsieh,T.H., Chou,S.Y.,
            Su,T.P., Hung,J.J., Chang,W.C., Lee,Y.C. and Chuang,J.Y.
  TITLE     The sigma-1 receptor-zinc finger protein 179 pathway protects
            against hydrogen peroxide-induced cell injury
  JOURNAL   Neuropharmacology 105, 1-9 (2016)
   PUBMED   26792191
REFERENCE   5  (bases 1 to 2923)
  AUTHORS   Lomash,R.M., Gu,X., Youle,R.J., Lu,W. and Roche,K.W.
  TITLE     Neurolastin, a Dynamin Family GTPase, Regulates Excitatory Synapses
            and Spine Density
  JOURNAL   Cell Rep 12 (5), 743-751 (2015)
   PUBMED   26212327
  REMARK    GeneRIF: identify neurolastin as a dynamin family GTPase that
            affects endosome size and spine density.
REFERENCE   6  (bases 1 to 2923)
  AUTHORS   Lin,D.Y., Huang,C.C., Hsieh,Y.T., Lin,H.C., Pao,P.C., Tsou,J.H.,
            Lai,C.Y., Hung,L.Y., Wang,J.M., Chang,W.C. and Lee,Y.C.
  TITLE     Analysis of the interaction between Zinc finger protein 179
            (Znf179) and promyelocytic leukemia zinc finger (Plzf)
  JOURNAL   J Biomed Sci 20 (1), 98 (2013)
   PUBMED   24359566
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 2923)
  AUTHORS   Pao,P.C., Huang,N.K., Liu,Y.W., Yeh,S.H., Lin,S.T., Hsieh,C.P.,
            Huang,A.M., Huang,H.S., Tseng,J.T., Chang,W.C. and Lee,Y.C.
  TITLE     A novel RING finger protein, Znf179, modulates cell cycle exit and
            neuronal differentiation of P19 embryonal carcinoma cells
  JOURNAL   Cell Death Differ 18 (11), 1791-1804 (2011)
   PUBMED   21566658
REFERENCE   8  (bases 1 to 2923)
  AUTHORS   Orimo,A., Inoue,S., Ikeda,K., Sato,M., Kato,A., Tominaga,N.,
            Suzuki,M., Noda,T., Watanabe,M. and Muramatsu,M.
  TITLE     Molecular cloning, localization, and developmental expression of
            mouse brain finger protein (Bfp)/ZNF179: distribution of bfp mRNA
            partially coincides with the affected areas of Smith-Magenis
            syndrome
  JOURNAL   Genomics 54 (1), 59-69 (1998)
   PUBMED   9806830
REFERENCE   9  (bases 1 to 2923)
  AUTHORS   Inoue,S., Orimo,A., Saito,T., Ikeda,K., Sakata,K., Hosoi,T.,
            Orimo,H., Ouchi,Y. and Muramatsu,M.
  TITLE     A novel RING finger protein, BFP, predominantly expressed in the
            brain
  JOURNAL   Biochem Biophys Res Commun 240 (1), 8-14 (1997)
   PUBMED   9367872
REFERENCE   10 (bases 1 to 2923)
  AUTHORS   Matsuda,Y., Inoue,S., Seki,N., Hosoi,T., Orimo,A., Muramatsu,M. and
            Hori,T.
  TITLE     Chromosome mapping of human (ZNF179), mouse, and rat genes for
            brain finger protein (bfp), a member of the RING finger family
  JOURNAL   Genomics 33 (2), 325-327 (1996)
   PUBMED   8660987
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            [WARNING] On May 2, 2024 this sequence was replaced by NM_138613.3.
            
            On Mar 2, 2021 this sequence version replaced NM_138613.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF054586.1, SRR26360194.354056.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-134               JAXUCZ010000010.1  46626014-46626147   c
            135-175             JAXUCZ010000010.1  46625829-46625869   c
            176-461             JAXUCZ010000010.1  46624801-46625086   c
            462-668             JAXUCZ010000010.1  46624451-46624657   c
            669-797             JAXUCZ010000010.1  46624214-46624342   c
            798-902             JAXUCZ010000010.1  46623907-46624011   c
            903-953             JAXUCZ010000010.1  46623486-46623536   c
            954-1010            JAXUCZ010000010.1  46623132-46623188   c
            1011-1085           JAXUCZ010000010.1  46622979-46623053   c
            1086-1206           JAXUCZ010000010.1  46622728-46622848   c
            1207-1376           JAXUCZ010000010.1  46622458-46622627   c
            1377-1430           JAXUCZ010000010.1  46622331-46622384   c
            1431-1505           JAXUCZ010000010.1  46622108-46622182   c
            1506-2923           JAXUCZ010000010.1  46620602-46622019   c
FEATURES             Location/Qualifiers
     source          1..2923
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q22"
     gene            1..2923
                     /gene="Rnf112"
                     /gene_synonym="Bfb; BFP; Zfp179; Znf179"
                     /note="ring finger protein 112"
                     /db_xref="GeneID:24916"
                     /db_xref="RGD:3986"
     exon            1..134
                     /gene="Rnf112"
                     /gene_synonym="Bfb; BFP; Zfp179; Znf179"
                     /inference="alignment:Splign:2.1.0"
     CDS             81..1976
                     /gene="Rnf112"
                     /gene_synonym="Bfb; BFP; Zfp179; Znf179"
                     /EC_number="2.3.2.27"
                     /note="brain finger protein; zinc finger protein 179"
                     /codon_start=1
                     /product="RING finger protein 112"
                     /protein_id="NP_619516.1"
                     /db_xref="GeneID:24916"
                     /db_xref="RGD:3986"
                     /translation="MPRPVLSVTAFCHRLGKRESKRSFMGNSSNSWSHASFPKLELGL
                     GQRPSPPRESPTCSICLERLREPISLDCGHDFCIRCFSTHRIPGCELPCCPECRKICK
                     QKKGLRSLGERMKLLPQRPLPPALQETCAVRAERLLLVRINASGGLILRMGAINRCLK
                     HPLARDTPVCLLAVLGEQHSGKSFLLDHLLRGLPGLESGDSTRPRAEGSLPGIRWGAN
                     GLTRGIWMWSHPFLLGKEGKKVAVFLVDTGDVMSPELSRETRVKLCALTMMLSSYQIL
                     NTSQELKDTDLGYLEMFVHVAEVMGKHYGMVPIQHLDLLVRDSSHHNKSGQGHVGDIL
                     QKLSGKYPKVQELLLGKRARCYLLPAPERQWVNKGQASPGGNTEDDFSHHFRAYISDV
                     LSTAPQHAKSRCQGYWSEGRAMARGDRRLLTGQQLAQEIKNLSGWMGKSGPSFSSPDE
                     MAAQLHDLRKVEAAKKEFEEYVRQQDIATKRIFSALRVLPDTMRNLLSTQKDAILARH
                     GVALLCKEREQTLEALEAELQAEAKAFMDSYTMRFCGHLAAVGGAVGAGLMGLAGGVV
                     GAGMAAAALAAEAGMVAAGAAVGATGAAVVGGGVGAGLAATVGCMEKEEDERVQGGDR
                     EPLLQEE"
     exon            135..175
                     /gene="Rnf112"
                     /gene_synonym="Bfb; BFP; Zfp179; Znf179"
                     /inference="alignment:Splign:2.1.0"
     exon            176..461
                     /gene="Rnf112"
                     /gene_synonym="Bfb; BFP; Zfp179; Znf179"
                     /inference="alignment:Splign:2.1.0"
     exon            462..668
                     /gene="Rnf112"
                     /gene_synonym="Bfb; BFP; Zfp179; Znf179"
                     /inference="alignment:Splign:2.1.0"
     exon            669..797
                     /gene="Rnf112"
                     /gene_synonym="Bfb; BFP; Zfp179; Znf179"
                     /inference="alignment:Splign:2.1.0"
     exon            798..902
                     /gene="Rnf112"
                     /gene_synonym="Bfb; BFP; Zfp179; Znf179"
                     /inference="alignment:Splign:2.1.0"
     exon            903..953
                     /gene="Rnf112"
                     /gene_synonym="Bfb; BFP; Zfp179; Znf179"
                     /inference="alignment:Splign:2.1.0"
     exon            954..1010
                     /gene="Rnf112"
                     /gene_synonym="Bfb; BFP; Zfp179; Znf179"
                     /inference="alignment:Splign:2.1.0"
     exon            1011..1085
                     /gene="Rnf112"
                     /gene_synonym="Bfb; BFP; Zfp179; Znf179"
                     /inference="alignment:Splign:2.1.0"
     exon            1086..1206
                     /gene="Rnf112"
                     /gene_synonym="Bfb; BFP; Zfp179; Znf179"
                     /inference="alignment:Splign:2.1.0"
     exon            1207..1376
                     /gene="Rnf112"
                     /gene_synonym="Bfb; BFP; Zfp179; Znf179"
                     /inference="alignment:Splign:2.1.0"
     exon            1377..1430
                     /gene="Rnf112"
                     /gene_synonym="Bfb; BFP; Zfp179; Znf179"
                     /inference="alignment:Splign:2.1.0"
     exon            1431..1505
                     /gene="Rnf112"
                     /gene_synonym="Bfb; BFP; Zfp179; Znf179"
                     /inference="alignment:Splign:2.1.0"
     exon            1506..2923
                     /gene="Rnf112"
                     /gene_synonym="Bfb; BFP; Zfp179; Znf179"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tctagctgtc cgtcctaccg ggaaaagatc tcggtgggtt tcctctctga gcatcggacc
       61 ctctgccatt ccagcctctc atgccgaggc cagtcctgtc agtcactgct ttttgtcatc
      121 ggcttggcaa acgggagagc aaacgaagct tcatgggaaa cagcagcaac agttggtccc
      181 atgcatcatt ccccaagctg gagctgggcc tgggacagcg tccctcccca ccccgggagt
      241 cgcctacctg ctccatctgt ctggaaaggc ttcgagagcc tatctcactg gactgtggcc
      301 acgacttctg catccgatgc ttcagcacac atcgcatccc aggctgtgag ctgccatgct
      361 gtcctgaatg ccggaaaatc tgtaagcaaa agaagggcct tcgcagtcta ggggagagga
      421 tgaagctcct acctcagcgg ccgctgcccc ctgcactgca ggagacctgt gctgtgagag
      481 cggagcgtct gctgttggta cgcatcaatg cctctggagg cctcatcctc aggatgggag
      541 ccataaaccg ctgcctgaag caccctctgg ccagggacac acctgtctgc ttgcttgctg
      601 tcctgggaga gcagcactca ggaaagtcct tcctcttgga ccacttgctc agaggcttac
      661 caggcctgga atccggagac agcactaggc ccagagcaga ggggtctctg cctggaatca
      721 gatggggtgc taatggtctc acgaggggca tctggatgtg gagtcacccc ttcctgctgg
      781 gaaaagaagg gaagaaggtg gctgtgttct tagtggacac aggagatgtc atgagcccag
      841 aactgagcag ggagacaagg gtcaagctct gtgccctcac catgatgctc agttcgtacc
      901 agatcctcaa cacctcccaa gagctgaagg acacagatct gggctatcta gagatgttcg
      961 ttcatgtggc tgaggtgatg ggcaaacatt atgggatggt acccatccag catctggatc
     1021 tcttagtccg tgactcttcc catcacaata agtcagggca ggggcacgtg ggtgatatac
     1081 tccagaagct gtccggcaaa taccccaagg tccaagagct gctcctaggg aaacgggccc
     1141 gctgttacct ccttcctgct cctgagagac agtgggtgaa caaaggccaa gcaagcccag
     1201 gaggcaacac agaagatgac ttctcccacc atttccgggc ctacatctcg gatgtgctga
     1261 gcacagcccc tcagcatgct aagagccgct gccaagggta ctggagtgag ggtcgcgcca
     1321 tggccagggg ggacagacgc ctactcacag ggcagcagct ggcacaggag atcaagaacc
     1381 tctccggctg gatggggaag agtgggccca gtttcagctc tccagatgag atggctgctc
     1441 aacttcatga cctgaggaaa gtggaagccg ccaagaagga gtttgaagag tatgtgagac
     1501 agcaggacat agccaccaag cgcatcttct ctgcactacg agtactgccc gacactatga
     1561 ggaacctcct ctctacccag aaggatgcta tcttggcccg ccatggtgtg gccctgttgt
     1621 gcaaggagag agagcagacc ttggaggccc tggaagccga gctgcaggca gaagccaagg
     1681 ccttcatgga ctcctacaca atgcgcttct gtggccacct ggccgcggta gggggcgctg
     1741 taggtgctgg actcatgggc ctggcagggg gtgtggtggg cgccggtatg gcggcagcag
     1801 cgttggctgc agaagctggg atggtggcag ccggggcagc ggtgggtgcc actggggctg
     1861 ctgtagttgg gggtggtgtg ggtgctgggc tggccgcgac ggtgggctgc atggagaaag
     1921 aggaagatga gagagttcaa ggaggagacc gagagcccct actccaggaa gaataacagc
     1981 taggagatgt cgaagcggga aatatgtgga aggcaggagg aagggtgtgg acatgccagg
     2041 gactcagaca agaccacgta tatactgggc gaatgcccca tgccaaacat tggctgagct
     2101 ggggttttaa ggtcggtccc gaaccctgag gaggcctctg gccatgaggc tgtgcttgga
     2161 gtgcagcaga tagggtgtaa ggcctgtttc tgactatggc taattgctat tcactggaac
     2221 ctaggatctc ccaccacata aggctccacc tcccctaccc ggctccagtt tatttccctg
     2281 gtgggtctca gcctggaagt ttggccctgg atcccgaacc ccatccgttt tacagttggg
     2341 ataggtccca gcataactcg ctttggagct gggggcccct aacagggaag acaaagggat
     2401 gggaatgata gagctataac tctagagtgg ccacttgttc ccaaaactgt tccggaaggc
     2461 cagacttggc tggcctccct gctcttcagt tgggtgtcca gatgtgtgtc ctgaaccgcc
     2521 ctgtacccca gcctcctgca gtcctcctaa gcctgtgccc tgtgccaagc ccatttggat
     2581 ggatcaacac agattacatg ccaaagaacc acacctctga ttgcattctg tgctaaagca
     2641 ggccctgcca ggctctgcca aagtgtggta aagggaagtg caggacatgg gctccgtctt
     2701 aaatacatcc ttccccttga gctgcggggc ctctgtgcca cactgtaaga ccccttggat
     2761 gcagccctct gaacgacaaa cccccagaga gcttgcgaac agggagcctc tttcggggaa
     2821 tggagatttc taaagagact tctgggctat taaactataa aggatgttgg gcatatgacc
     2881 ctttatttta tataaaaata aaatgtgtgt gtgtgaatgg caa
//
