LOCUS       NM_001401703             608 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ribonuclease H2, subunit C (Rnaseh2c), mRNA.
ACCESSION   NM_001401703 XM_002728856
VERSION     NM_001401703.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 608)
  AUTHORS   Figiel,M., Chon,H., Cerritelli,S.M., Cybulska,M., Crouch,R.J. and
            Nowotny,M.
  TITLE     The structural and biochemical characterization of human RNase H2
            complex reveals the molecular basis for substrate recognition and
            Aicardi-Goutieres syndrome defects
  JOURNAL   J Biol Chem 286 (12), 10540-10550 (2011)
   PUBMED   21177858
REFERENCE   2  (bases 1 to 608)
  AUTHORS   Shaban,N.M., Harvey,S., Perrino,F.W. and Hollis,T.
  TITLE     The structure of the mammalian RNase H2 complex provides insight
            into RNA.NA hybrid processing to prevent immune dysfunction
  JOURNAL   J Biol Chem 285 (6), 3617-3624 (2010)
   PUBMED   19923215
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Feb 18, 2022 this sequence version replaced XM_002728856.6.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CK842868.1, CK601207.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-190               JAXUCZ010000001.1  212323962-212324151
            191-372             JAXUCZ010000001.1  212324265-212324446
            373-492             JAXUCZ010000001.1  212324522-212324641
            493-608             JAXUCZ010000001.1  212324896-212325011
FEATURES             Location/Qualifiers
     source          1..608
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..608
                     /gene="Rnaseh2c"
                     /note="ribonuclease H2, subunit C"
                     /db_xref="GeneID:100361939"
                     /db_xref="RGD:2319141"
     exon            1..190
                     /gene="Rnaseh2c"
                     /inference="alignment:Splign:2.1.0"
     CDS             19..519
                     /gene="Rnaseh2c"
                     /note="AYP1 protein"
                     /codon_start=1
                     /product="ribonuclease H2 subunit C"
                     /protein_id="NP_001388632.1"
                     /db_xref="GeneID:100361939"
                     /db_xref="RGD:2319141"
                     /translation="MKNPEEAGDDKQRIHLRPGSLRGAAPAKLHLLPCDVLVSRPAPV
                     ERFFTPAVRHGADGLQVSFRGRGLRGEDVAVPPGFAGFVMVTEEMGEGLIGKLNFSGD
                     AEDKADEAQEPLERDFDRFIGATGSFSHFTLWGLETVPGPDAKVHRALGWPSLAAAIH
                     AQVPED"
     exon            191..372
                     /gene="Rnaseh2c"
                     /inference="alignment:Splign:2.1.0"
     exon            373..492
                     /gene="Rnaseh2c"
                     /inference="alignment:Splign:2.1.0"
     exon            493..608
                     /gene="Rnaseh2c"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aacctacaag catccgagat gaagaacccg gaggaagctg gggacgataa acagcgtatt
       61 cacctgcgcc ctggctcact gcgtggcgcc gcaccagcta agctgcacct cctgccatgt
      121 gacgttctgg tcagccggcc cgccccggtt gaacgcttct tcacgcccgc cgtccgccac
      181 ggtgcagacg gactgcaggt gtcgtttcgc ggtcgtggcc tgcggggcga agatgtagct
      241 gtcccgccag ggtttgcggg attcgtgatg gtgacagaag agatgggaga ggggctgata
      301 gggaagctga acttctcagg ggacgcggag gacaaagcgg acgaggcaca ggagccgctg
      361 gagcgggact ttgaccgctt tatcggagcc accggcagct tcagtcactt caccttgtgg
      421 ggtctggaaa cggtccctgg tccagatgcc aaagtgcata gggccctagg ttggcccagc
      481 cttgctgcag cgattcacgc acaggtgcca gaggactgag agccagagca tgaaaatgaa
      541 agtcacagag cccttcacac cactttggag ccactgtttc tatcccaata aatgagatct
      601 tcacaaca
//
