LOCUS       NM_001012467            1342 bp    mRNA    linear   ROD 10-DEC-2024
DEFINITION  Rattus norvegicus ribonuclease A family member 10 (Rnase10), mRNA.
ACCESSION   NM_001012467 XM_223962
VERSION     NM_001012467.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1342)
  AUTHORS   Premzl,M.
  TITLE     Comparative genomic analysis of eutherian ribonuclease A genes
  JOURNAL   Mol Genet Genomics 289 (2), 161-167 (2014)
   PUBMED   24337645
REFERENCE   2  (bases 1 to 1342)
  AUTHORS   Krutskikh,A., Poliandri,A., Cabrera-Sharp,V., Dacheux,J.L.,
            Poutanen,M. and Huhtaniemi,I.
  TITLE     Epididymal protein Rnase10 is required for post-testicular sperm
            maturation and male fertility
  JOURNAL   FASEB J 26 (10), 4198-4209 (2012)
   PUBMED   22750516
REFERENCE   3  (bases 1 to 1342)
  AUTHORS   Krutskikh,A., De Gendt,K., Sharp,V., Verhoeven,G., Poutanen,M. and
            Huhtaniemi,I.
  TITLE     Targeted inactivation of the androgen receptor gene in murine
            proximal epididymis causes epithelial hypotrophy and obstructive
            azoospermia
  JOURNAL   Endocrinology 152 (2), 689-696 (2011)
   PUBMED   21084446
REFERENCE   4  (bases 1 to 1342)
  AUTHORS   Cho,S., Beintema,J.J. and Zhang,J.
  TITLE     The ribonuclease A superfamily of mammals and birds: identifying
            new members and tracing evolutionary histories
  JOURNAL   Genomics 85 (2), 208-220 (2005)
   PUBMED   15676279
REFERENCE   5  (bases 1 to 1342)
  AUTHORS   Castella,S., Fouchecourt,S., Teixeira-Gomes,A.P., Vinh,J.,
            Belghazi,M., Dacheux,F. and Dacheux,J.L.
  TITLE     Identification of a member of a new RNase a family specifically
            secreted by epididymal caput epithelium
  JOURNAL   Biol Reprod 70 (2), 319-328 (2004)
   PUBMED   14561640
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000015.1.
            
            On Jan 13, 2022 this sequence version replaced NM_001012467.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AI639130.1, SRR26360186.1619407.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMN06680412
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on single protein-coding
                                                transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-110               JAXUCZ010000015.1  26700219-26700328
            111-1342            JAXUCZ010000015.1  26701450-26702681
FEATURES             Location/Qualifiers
     source          1..1342
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p14"
     gene            1..1342
                     /gene="Rnase10"
                     /gene_synonym="Rah1; RGD1310415"
                     /note="ribonuclease A family member 10"
                     /db_xref="GeneID:305840"
                     /db_xref="RGD:1310415"
     exon            1..110
                     /gene="Rnase10"
                     /gene_synonym="Rah1; RGD1310415"
                     /inference="alignment:Splign:2.1.0"
     exon            111..1342
                     /gene="Rnase10"
                     /gene_synonym="Rah1; RGD1310415"
                     /inference="alignment:Splign:2.1.0"
     CDS             116..754
                     /gene="Rnase10"
                     /gene_synonym="Rah1; RGD1310415"
                     /note="ribonuclease-like protein 10; ribonuclease 10;
                     protein Train A; inactive ribonuclease-like protein 10;
                     ribonuclease A h1; ribonuclease, RNase A family, 10
                     (non-active)"
                     /codon_start=1
                     /product="inactive ribonuclease-like protein 10 precursor"
                     /protein_id="NP_001012485.1"
                     /db_xref="GeneID:305840"
                     /db_xref="RGD:1310415"
                     /translation="MKVTLVHLLFMMLLLLLGLGVGLGLGLHMAAAILENQPLDEFWP
                     SDSQDTAEATEEGQGTRTTEALVLDNKEMAVPVWSEDTVLSEDEVGGSRMLRAKTLLQ
                     SKQGYLKFDLNIRDCNVMMAHKIKEHNQSCINDYTFIHEDPSTVGAVCNSPLVDCDLK
                     GGKCHKSPRPFDLTLCKLAKPGQVTPNCHYLTYITEKVIIITCNNTKQLEIK"
ORIGIN      
        1 ttttatggag agcagcttct gggttcggct ctcagagaag gaagttccag gagagcagaa
       61 ctgggggcat aggaagagac aagagtacct gaagctgctt acaagtgtgg gcaaaatgaa
      121 ggtgacactg gtgcatctgt tgttcatgat gttactgctg ttgctaggac tgggggtggg
      181 gctggggctg ggccttcaca tggctgctgc catcctggag aatcagccac tggatgagtt
      241 ttggcccagt gactcccagg acacagctga ggccactgaa gagggacagg gcaccaggac
      301 cacagaagcc ctggtacttg acaacaaaga aatggcagta cctgtctggt cagaagatac
      361 tgtcctcagt gaagatgaag tggggggaag caggatgctg agagccaaga ccctccttca
      421 gagcaagcaa ggctacctta agtttgactt gaacatccgg gactgtaacg tcatgatggc
      481 ccacaagata aaggagcaca atcagagctg cataaacgat tatacattca tccatgagga
      541 tccaagcaca gtcggagccg tctgtaacag tcccctggtt gactgtgatc tcaagggagg
      601 caaatgtcac aaaagccccc ggccttttga cctgacattg tgcaagttgg ccaaaccagg
      661 ccaagtcact cccaactgcc actatctgac ttacataact gaaaaggtca ttatcataac
      721 atgcaacaac acgaaacaac tggagattaa atgaggcagc gcgtgccttt ccctcctctc
      781 cgtctcgttg cctctgtttt ttgcgtttct gcttgctgat gcttctgtcc cctccttggg
      841 ttccctaact agaaggaaga tcctgggaag agacgatgga acattgctga tctttgtctt
      901 ctgagaatat aattattctt tgtgttggga gggtcatcca acttgcattt tgtcctgggg
      961 gtcagaaatg gcaaaataat aatgtgtagt ttctcctaga tgtctctcac cttcaatccc
     1021 tgccctgcaa aggcctagct ctagacccta ccttagccat ggtcatcagc ctgattcctg
     1081 aactgagtac accttgggtg tggactagag gaatttaatg cctcctttac ccacctgctt
     1141 ccctgctacc taccttaggc ctctgcgtgc tacctacatg tgctaatccc agactcctgg
     1201 gccctgcaca acacagcatg cttctctgca gcagatgcaa cacaagggat tctacctagg
     1261 actgtgtctg gaaagccacg tggttaggct tcttttccag agcctgctgt aaggtggtat
     1321 agggcatagg ccagaagatc aa
//
