LOCUS       NM_001040128            2076 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus required for meiotic nuclear division 1 homolog
            (Rmnd1), mRNA.
ACCESSION   NM_001040128 XM_006227834 XM_214758
VERSION     NM_001040128.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2076)
  AUTHORS   Li,D., Zhao,Q., Xie,L., Wang,C., Tian,Z., Tang,H., Xia,T. and
            Wang,A.
  TITLE     Fluoride impairs mitochondrial translation by targeting
            miR-221-3p/c-Fos/RMND1 axis contributing to neurodevelopment
            defects
  JOURNAL   Sci Total Environ 869, 161738 (2023)
   PUBMED   36690096
  REMARK    GeneRIF: Fluoride impairs mitochondrial translation by targeting
            miR-221-3p/c-Fos/RMND1 axis contributing to neurodevelopment
            defects.
REFERENCE   2  (bases 1 to 2076)
  AUTHORS   Janer,A., van Karnebeek,C.D., Sasarman,F., Antonicka,H., Al
            Ghamdi,M., Shyr,C., Dunbar,M., Stockler-Ispiroglu,S., Ross,C.J.,
            Vallance,H., Dionne,J., Wasserman,W.W. and Shoubridge,E.A.
  TITLE     RMND1 deficiency associated with neonatal lactic acidosis,
            infantile onset renal failure, deafness, and multiorgan involvement
  JOURNAL   Eur J Hum Genet 23 (10), 1301-1307 (2015)
   PUBMED   25604853
REFERENCE   3  (bases 1 to 2076)
  AUTHORS   Xia,H.F., Sun,J., Sun,Q.H., Yang,Y. and Peng,J.P.
  TITLE     Implantation-associated gene-1 (Iag-1): a novel gene involved in
            the early process of embryonic implantation in rat
  JOURNAL   Hum Reprod 23 (7), 1581-1593 (2008)
   PUBMED   18296448
  REMARK    GeneRIF: Overexpression of Iag-1 can inhibit endometrial stromal
            cell proliferation and induce endometrial stroma cells apoptosis,
            and p53 and Bax may play an important role in the process of
            Iag-1-induced apoptosis.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On or before Oct 4, 2022 this sequence version replaced
            XM_006227834.2, NM_001040128.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.642.1, SRR26643294.495.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-74                JAXUCZ010000001.1  43299609-43299682   c
            75-595              JAXUCZ010000001.1  43288885-43289405   c
            596-704             JAXUCZ010000001.1  43286182-43286290   c
            705-780             JAXUCZ010000001.1  43283763-43283838   c
            781-820             JAXUCZ010000001.1  43282389-43282428   c
            821-921             JAXUCZ010000001.1  43278622-43278722   c
            922-1028            JAXUCZ010000001.1  43277362-43277468   c
            1029-1093           JAXUCZ010000001.1  43276316-43276380   c
            1094-1170           JAXUCZ010000001.1  43274831-43274907   c
            1171-1291           JAXUCZ010000001.1  43271713-43271833   c
            1292-1408           JAXUCZ010000001.1  43266356-43266472   c
            1409-2076           JAXUCZ010000001.1  43265207-43265874   c
FEATURES             Location/Qualifiers
     source          1..2076
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q11"
     gene            1..2076
                     /gene="Rmnd1"
                     /gene_synonym="Iag-1; RGD1309546"
                     /note="required for meiotic nuclear division 1 homolog"
                     /db_xref="GeneID:292268"
                     /db_xref="RGD:1309546"
     exon            1..74
                     /gene="Rmnd1"
                     /gene_synonym="Iag-1; RGD1309546"
                     /inference="alignment:Splign:2.1.0"
     exon            75..595
                     /gene="Rmnd1"
                     /gene_synonym="Iag-1; RGD1309546"
                     /inference="alignment:Splign:2.1.0"
     CDS             89..1441
                     /gene="Rmnd1"
                     /gene_synonym="Iag-1; RGD1309546"
                     /note="implantation-associated gene-1"
                     /codon_start=1
                     /product="required for meiotic nuclear division protein 1
                     homolog"
                     /protein_id="NP_001035217.2"
                     /db_xref="GeneID:292268"
                     /db_xref="RGD:1309546"
                     /translation="MPARQLQTLAGLHSISSKAHQCQRLTRLTLRPLTKFESTACHNS
                     LTIQQHLDSFLPSITADSLNKPKIPETSRVISNASRLFPLNAVHWLDRKEHRPSMHAF
                     GTHRSMTHKPNFLCSKWFIKAVKRHHSSVSNEALVPKQDLPQIKRPLKASRTRQPSRT
                     NLPDLSVNEDLMQCTAFATADEYHLGSLSQELVSCGYVEVTSLPRDAANILVMGVESS
                     AKEGDAGTIFLFREGAAVFWNVKDKTMKHVMQVLERHETQPYEVALVHWENEELNYTK
                     TEGQSKLHRGEIKLNSELDLDDSILEKFAFSNALCLSVKLAIWEATLDKFIESIQSIP
                     EALKAGKKVKLSHKEVMQKMGELFALRHRINLSSDFLITPDFYWDRANLEELYDKTCQ
                     FLSITRRVKVMNEKLQHCMELTDLMRNHLNEKRALRLEWMIVILITIEVMFELGRVFF
                     "
     exon            596..704
                     /gene="Rmnd1"
                     /gene_synonym="Iag-1; RGD1309546"
                     /inference="alignment:Splign:2.1.0"
     exon            705..780
                     /gene="Rmnd1"
                     /gene_synonym="Iag-1; RGD1309546"
                     /inference="alignment:Splign:2.1.0"
     exon            781..820
                     /gene="Rmnd1"
                     /gene_synonym="Iag-1; RGD1309546"
                     /inference="alignment:Splign:2.1.0"
     exon            821..921
                     /gene="Rmnd1"
                     /gene_synonym="Iag-1; RGD1309546"
                     /inference="alignment:Splign:2.1.0"
     exon            922..1028
                     /gene="Rmnd1"
                     /gene_synonym="Iag-1; RGD1309546"
                     /inference="alignment:Splign:2.1.0"
     exon            1029..1093
                     /gene="Rmnd1"
                     /gene_synonym="Iag-1; RGD1309546"
                     /inference="alignment:Splign:2.1.0"
     exon            1094..1170
                     /gene="Rmnd1"
                     /gene_synonym="Iag-1; RGD1309546"
                     /inference="alignment:Splign:2.1.0"
     exon            1171..1291
                     /gene="Rmnd1"
                     /gene_synonym="Iag-1; RGD1309546"
                     /inference="alignment:Splign:2.1.0"
     exon            1292..1408
                     /gene="Rmnd1"
                     /gene_synonym="Iag-1; RGD1309546"
                     /inference="alignment:Splign:2.1.0"
     exon            1409..2076
                     /gene="Rmnd1"
                     /gene_synonym="Iag-1; RGD1309546"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agagtgtgtt tccgcagggg ttcctacggc gggagcgtgc gcgtgggcgt cgcggtcgtc
       61 ttctccgcgc acagcctaag atgtgatcat gccagccaga caactccaaa ccctggcagg
      121 tttgcacagc atatcatcaa aggctcatca gtgccagaga cttactaggc ttacattaag
      181 accacttaca aaatttgaaa gtacagcatg ccacaacagc ctgacaatac agcaacattt
      241 agactcattc cttccgagca taacagctga cagtttgaat aagcccaaga tcccggaaac
      301 gagccgggta atatcaaacg caagcagact ctttccgtta aacgctgtcc attggttgga
      361 tagaaaagaa catcggccaa gcatgcatgc ctttgggact cacaggagca tgacccacaa
      421 accaaatttc ttgtgttcta agtggtttat aaaagcagtg aaaaggcatc actcgtctgt
      481 atcaaatgaa gcccttgttc ccaaacaaga ccttccacag atcaagaggc cactgaaagc
      541 atcccggacc cggcaaccat ccaggaccaa ccttccagat ctgtctgtga atgaggacct
      601 gatgcagtgc acagcgtttg caacagcaga tgaatatcac ctgggaagtc tgtctcaaga
      661 gctggtctcc tgtggctatg tggaagtgac aagcctgcct agagatgcag caaatatttt
      721 ggttatgggt gtggagagtt ctgcaaaaga aggcgatgcc ggaacaattt tcttgttcag
      781 ggaaggagct gctgtgttct ggaatgtaaa agacaaaact atgaagcacg tgatgcaagt
      841 tctagagaga cacgaaaccc agccctatga agtggctctg gttcactggg agaacgaaga
      901 gctgaactac acaaaaacag aggggcaatc caaactgcac agaggggaaa tcaagctgaa
      961 ttctgagctg gacttagatg actccatttt agagaagttt gccttctcca acgctctttg
     1021 cctctcagtg aaactggcta tttgggaagc aacactggac aaatttattg agtctattca
     1081 gtccatccca gaggctttaa aagctgggaa gaaagtcaaa ctgtctcata aagaagttat
     1141 gcagaaaatg ggtgagctct ttgccctcag gcatcgaata aacctgagct cagacttctt
     1201 gatcacccct gacttctact gggacagagc gaacctggag gagctttacg acaagacctg
     1261 ccagttcctc agcatcactc gaagagttaa ggtcatgaat gaaaaactgc aacactgcat
     1321 ggaactaaca gacctaatgc gcaatcacct caatgagaag cgagcgctcc gcctggagtg
     1381 gatgatcgtc atcctcatca ccattgaggt aatgttcgag ctggggagag tcttcttctg
     1441 atcttgtgat catgaaagca ccactggaag agagtagtca agttctgcaa ccaaaaaacc
     1501 agcgttcact actggtgact cttaaatcaa ccctttaaat caaggacctg tcagtgcaca
     1561 tgggacacac acctggaatc tccaggctct ggaagccaga gcaggaagat cctaagttcc
     1621 agactagccc tgggctacat agggaagccc agccatcctg ggaaagcaga ggcagactgc
     1681 ccagtgtgag gccaacagta acacagcagg actgtctcaa aatggtcctt tcagctctta
     1741 attatattgc tacctgaata aaaatcccga gtatggtgtt tggatcaaca tactcaacag
     1801 ttcaaaagga aaacgtttca tcagcttaaa ggtcagttaa ccatctgaac atacagaatg
     1861 tcttagcaaa aggccaactc tggacaccac tcttgactct ggagtcatgg gcctggctta
     1921 agaaccacac acttgtgaga tatatgttgt tttggcagga atacactttc tacctgtaac
     1981 attgaggaag tcagtctctc tacaagcaca ctgtattgtg tggaggactg atggatctca
     2041 tacctccaac acataaaatt aaaagacgta attctc
//
