LOCUS       NM_001014046            2195 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus regulator of microtubule dynamics 3 (Rmdn3),
            mRNA.
ACCESSION   NM_001014046 XM_230467
VERSION     NM_001014046.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2195)
  AUTHORS   Gomez-Suaga,P., Perez-Nievas,B.G., Glennon,E.B., Lau,D.H.W.,
            Paillusson,S., Morotz,G.M., Cali,T., Pizzo,P., Noble,W. and
            Miller,C.C.J.
  TITLE     The VAPB-PTPIP51 endoplasmic reticulum-mitochondria tethering
            proteins are present in neuronal synapses and regulate synaptic
            activity
  JOURNAL   Acta Neuropathol Commun 7 (1), 35 (2019)
   PUBMED   30841933
  REMARK    GeneRIF: VAPB-PTPIP51 mitochondrial tethering proteins are present
            in synapses and regulate synaptic activity.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2195)
  AUTHORS   Orieux,G., Slembrouck,A., Bensaid,M., Sahel,J.A. and Goureau,O.
  TITLE     The protein tyrosine phosphatase interacting protein 51 (PTPIP51)
            is required for the differentiation of photoreceptors
  JOURNAL   Neuroscience 300, 276-285 (2015)
   PUBMED   25999297
  REMARK    GeneRIF: Results showed that PTPIP51 expressed in post-natal retina
            contributes to the final differentiation of photoreceptors,
            probably by participating in the complex formation of the
            photoreceptor segments
REFERENCE   3  (bases 1 to 2195)
  AUTHORS   De Vos,K.J., Morotz,G.M., Stoica,R., Tudor,E.L., Lau,K.F.,
            Ackerley,S., Warley,A., Shaw,C.E. and Miller,C.C.
  TITLE     VAPB interacts with the mitochondrial protein PTPIP51 to regulate
            calcium homeostasis
  JOURNAL   Hum Mol Genet 21 (6), 1299-1311 (2012)
   PUBMED   22131369
REFERENCE   4  (bases 1 to 2195)
  AUTHORS   Stenzinger,A., Schreiner,D., Tag,C. and Wimmer,M.
  TITLE     Expression of the novel protein PTPIP51 in rat liver: an
            immunohistochemical study
  JOURNAL   Histochem Cell Biol 128 (1), 77-84 (2007)
   PUBMED   17551746
  REMARK    GeneRIF: Immunostaining showed expression of PTPIP51 protein in
            distinct non-parenchymal cells.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DN931790.1, BC082081.1 and BQ210660.1.
            
            On Oct 13, 2007 this sequence version replaced NM_001014046.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC082081.1, SRR8487231.78343.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMEA5760393
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-38                DN931790.1         33-70
            39-2174             BC082081.1         1-2136
            2175-2195           BQ210660.1         1-21                c
FEATURES             Location/Qualifiers
     source          1..2195
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q35"
     gene            1..2195
                     /gene="Rmdn3"
                     /gene_synonym="Fam82a2; Fam82c; Ptpip51; RGD1308697;
                     Rmd-3"
                     /note="regulator of microtubule dynamics 3"
                     /db_xref="GeneID:311328"
                     /db_xref="RGD:1308697"
     exon            1..83
                     /gene="Rmdn3"
                     /gene_synonym="Fam82a2; Fam82c; Ptpip51; RGD1308697;
                     Rmd-3"
                     /inference="alignment:Splign:2.1.0"
     exon            84..277
                     /gene="Rmdn3"
                     /gene_synonym="Fam82a2; Fam82c; Ptpip51; RGD1308697;
                     Rmd-3"
                     /inference="alignment:Splign:2.1.0"
     CDS             91..1506
                     /gene="Rmdn3"
                     /gene_synonym="Fam82a2; Fam82c; Ptpip51; RGD1308697;
                     Rmd-3"
                     /note="family with sequence similarity 82, member C;
                     protein tyrosine phosphatase-interacting protein 51;
                     family with sequence similarity 82, member A2; regulator
                     of microtubule dynamics protein 3-like"
                     /codon_start=1
                     /product="regulator of microtubule dynamics protein 3"
                     /protein_id="NP_001014068.1"
                     /db_xref="GeneID:311328"
                     /db_xref="RGD:1308697"
                     /translation="MSRLGALGGSRAGLGLLLGTAAGLGFLCVLYSQRWKRTQRHGRS
                     QSLPNSLDYAQTSERGRQVTQLRAIPGEAGDAAMLSSLPQEGQEKVLDRLDFVLTSLM
                     ALRREVEELQRSLQGLAGEIVGEVRSHMEENQRVARRRRFPFARERSDSTGSSSVYFT
                     ASSGATLTDAESEGGYTTANAESDYERDSDKESEDAEDEVSCETVKMGRKDSLDLDME
                     VASSPASAALEDDDSSGLEDVQLLLQQADELHQGSEQNKQEGFQLLLNNKLAYGSRQD
                     FLWRLARAYSDMTELTEEESEKKSYALNGKEEAEAALKKGDESAASHLWYAVLCGQLA
                     EHEGISKRIQSGFSFKEHVDKAIELQPEDPRGHFLLGRWCYQVSHLSWLEKKTATALF
                     ESPLSATVQDALQSFLKAEELQPGFSKAGRVYISKCYRELGKNSEARKWLNLAQELPN
                     ITNEDSAFQKDLEELEVILGK"
     exon            278..470
                     /gene="Rmdn3"
                     /gene_synonym="Fam82a2; Fam82c; Ptpip51; RGD1308697;
                     Rmd-3"
                     /inference="alignment:Splign:2.1.0"
     exon            471..614
                     /gene="Rmdn3"
                     /gene_synonym="Fam82a2; Fam82c; Ptpip51; RGD1308697;
                     Rmd-3"
                     /inference="alignment:Splign:2.1.0"
     exon            615..900
                     /gene="Rmdn3"
                     /gene_synonym="Fam82a2; Fam82c; Ptpip51; RGD1308697;
                     Rmd-3"
                     /inference="alignment:Splign:2.1.0"
     exon            901..1003
                     /gene="Rmdn3"
                     /gene_synonym="Fam82a2; Fam82c; Ptpip51; RGD1308697;
                     Rmd-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1004..1064
                     /gene="Rmdn3"
                     /gene_synonym="Fam82a2; Fam82c; Ptpip51; RGD1308697;
                     Rmd-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1065..1140
                     /gene="Rmdn3"
                     /gene_synonym="Fam82a2; Fam82c; Ptpip51; RGD1308697;
                     Rmd-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1141..1218
                     /gene="Rmdn3"
                     /gene_synonym="Fam82a2; Fam82c; Ptpip51; RGD1308697;
                     Rmd-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1219..1317
                     /gene="Rmdn3"
                     /gene_synonym="Fam82a2; Fam82c; Ptpip51; RGD1308697;
                     Rmd-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1318..1371
                     /gene="Rmdn3"
                     /gene_synonym="Fam82a2; Fam82c; Ptpip51; RGD1308697;
                     Rmd-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1372..1452
                     /gene="Rmdn3"
                     /gene_synonym="Fam82a2; Fam82c; Ptpip51; RGD1308697;
                     Rmd-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1453..2178
                     /gene="Rmdn3"
                     /gene_synonym="Fam82a2; Fam82c; Ptpip51; RGD1308697;
                     Rmd-3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctggtgacgc ggattaagga cgtcaagatc attgacagcg tgaatccgtg gtggctgctg
       61 ctgccatggt ggctggcggc tgggtacact atgtctagac tgggggccct gggcggctcc
      121 cgcgccgggt tgggactgtt acttggtact gccgccggcc tgggattcct gtgtgtcctc
      181 tacagtcaac gatggaaacg gacccaacgc catggccgga gccagagtct gcccaactcc
      241 ctggactatg cgcagacttc agagcgtgga cgccaggtga cacagttgcg ggctatccca
      301 ggtgaagctg gagatgctgc catgctgtcc agcctcccac aagaaggaca ggagaaggtg
      361 ctggaccgcc tggactttgt gctgaccagt cttatggcac tgcgacggga ggtagaggag
      421 cttcagagaa gcctgcaagg cctggctggg gagattgtcg gggaggttcg atctcatatg
      481 gaggagaacc agagagtggc tcggcggcgc aggttccctt ttgccaggga gaggagtgac
      541 tccactggct ccagctccgt gtatttcacc gcctcctcag gggctacact cacagatgcg
      601 gagagtgaag gaggttatac gacagccaat gcagaatctg actatgagcg ggactctgac
      661 aaggagagtg aggatgctga agatgaagta agctgtgaga ccgtgaagat ggggaggaag
      721 gattctctgg accttgatat ggaggtagct tcaagtcccg cgtctgctgc cttggaggat
      781 gatgactcct caggtcttga ggatgtgcag ttgctcctgc agcaggcgga tgagctgcac
      841 cagggcagtg agcagaacaa gcaggaaggt ttccagctgc tgctcaacaa taagctggcg
      901 tatgggagcc gacaagactt tctgtggcgc ctggcccggg cctacagtga catgactgag
      961 cttactgagg aggagagcga gaagaagtca tatgccctaa atggaaaaga agaagcagag
     1021 gctgctctga agaaaggaga tgagagtgct gcaagccacc tgtggtatgc agtgctttgt
     1081 ggtcagctgg ctgagcatga gggcatctcg aagcgtatcc agagtggctt tagcttcaag
     1141 gaacatgtgg acaaagccat tgaacttcag ccagaagacc ccaggggtca ctttcttctt
     1201 ggcaggtggt gctaccaggt ttctcatttg agctggttgg agaaaaaaac agctacagcc
     1261 ttgtttgaaa gcccccttag tgccactgtg caggatgccc tgcagagctt cctcaaggct
     1321 gaggagcttc agccagggtt ttcaaaagct ggacgggtat atatttctaa gtgctataga
     1381 gaattaggaa aaaactctga agctagaaag tggctgaatt tggctcagga gctgccaaac
     1441 atcactaatg aggattcagc tttccaaaaa gacctggaag aactggaagt aattttagga
     1501 aaataatcac atttcaatta ctgggggcca ctacttaatg cggaagagaa aatcaagttg
     1561 cttttcctcc tgtgactcac tgagttcaca agcaagatgt cttggcccct ggagatgtga
     1621 ctgtaccacc atcatccctc agtttttcat gttatcacta atctaccaca atttaaattg
     1681 gggaatgtac ttgcagctaa ggtttctgct ttcttcctct taagtgaatt cttgaaaaat
     1741 caagacagta tagccatagg gtttagtgtg gacacagccc agaaggccaa gagctgagaa
     1801 cgaagcagca gaactgtctt ccagctgcca gtgaggtaga tgaacttcaa agagccacgg
     1861 caacaaagca taggacttgt aatctttttt tgctaatatt caacacgtat ttattgtcct
     1921 ttaatgtcat accttaccta tgaggaaaga aggagccagc acagcccagg tactgctctc
     1981 ttaccaccca tcatggagac tctacctata ttcctgggct gagggctgga ccacgggact
     2041 tccagagttc tggcagcttt tgggatgaca gcactggcaa agggtctata aatatatttt
     2101 gaaagtgatc tatctgaaga ggtacctgga atattttttg gtacaaatta gaaataaact
     2161 aaatttgatt agaaggtaaa aaaaaaaaaa aaaaa
//
