LOCUS       NM_001014083            2364 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Rattus norvegicus RNA 5'-phosphate and 3'-OH ligase 1 (Rlig1),
            mRNA.
ACCESSION   NM_001014083 XM_235096
VERSION     NM_001014083.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2364)
  AUTHORS   Nagamachi,A., Matsui,H., Asou,H., Ozaki,Y., Aki,D., Kanai,A.,
            Takubo,K., Suda,T., Nakamura,T., Wolff,L., Honda,H. and Inaba,T.
  TITLE     Haploinsufficiency of SAMD9L, an endosome fusion facilitator,
            causes myeloid malignancies in mice mimicking human diseases with
            monosomy 7
  JOURNAL   Cancer Cell 24 (3), 305-317 (2013)
   PUBMED   24029230
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB733499.1, CK475399.1, CK478081.1 and JAXUCZ010000007.1.
            
            On Oct 23, 2007 this sequence version replaced NM_001014083.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079461.1, SRR26643296.19517.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-64                CB733499.1         59-122
            65-721              CK475399.1         52-708
            722-739             CK478081.1         689-706
            740-897             JAXUCZ010000007.1  37287693-37287850   c
            898-2364            JAXUCZ010000007.1  37284596-37286062   c
FEATURES             Location/Qualifiers
     source          1..2364
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q21"
     gene            1..2364
                     /gene="Rlig1"
                     /gene_synonym="RGD1307947; Rnl"
                     /note="RNA 5'-phosphate and 3'-OH ligase 1"
                     /db_xref="GeneID:314788"
                     /db_xref="RGD:1307947"
     exon            1..198
                     /gene="Rlig1"
                     /gene_synonym="RGD1307947; Rnl"
                     /inference="alignment:Splign:2.1.0"
     CDS             109..1086
                     /gene="Rlig1"
                     /gene_synonym="RGD1307947; Rnl"
                     /EC_number="6.5.1.3"
                     /note="uncharacterized protein C12orf29 homolog; RNA
                     ligase"
                     /codon_start=1
                     /product="RNA ligase 1"
                     /protein_id="NP_001014105.2"
                     /db_xref="GeneID:314788"
                     /db_xref="RGD:1307947"
                     /translation="MNRLGSVQRKMPCVFVTEVKAEPSAKREHQPFKVLATETLSEKA
                     LDADVYNAVATEKVDGTCCYVTNYKGQPYLWARLDRKPNKQADKRFKKFLHSKENAKE
                     FHWNTEEDFKPVPECWIPAKEIEKQNGKPVPDENGHIPGWVPVEKNSKQYCWHSSVVS
                     YEFGIALVLRHHPDDPGVLEISAVPLSELLEQTLELIGTNINGNPYGLGSKKYPLHFL
                     TPHGAFQVRNLPTLKHNDLLSWFEGCREGQIEGIVWHCGDGCLIKVHRHHLGLCWPLP
                     DTYMNSKPVIINMNLDKYDCAFDHQSLFNKFSKIDKQKFDRLKDITLDI"
     exon            199..316
                     /gene="Rlig1"
                     /gene_synonym="RGD1307947; Rnl"
                     /inference="alignment:Splign:2.1.0"
     exon            317..412
                     /gene="Rlig1"
                     /gene_synonym="RGD1307947; Rnl"
                     /inference="alignment:Splign:2.1.0"
     exon            413..529
                     /gene="Rlig1"
                     /gene_synonym="RGD1307947; Rnl"
                     /inference="alignment:Splign:2.1.0"
     exon            530..727
                     /gene="Rlig1"
                     /gene_synonym="RGD1307947; Rnl"
                     /inference="alignment:Splign:2.1.0"
     exon            728..897
                     /gene="Rlig1"
                     /gene_synonym="RGD1307947; Rnl"
                     /inference="alignment:Splign:2.1.0"
     exon            898..2364
                     /gene="Rlig1"
                     /gene_synonym="RGD1307947; Rnl"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttgacggtgc tgcttggatc ctctggctgg tgtttggatt ctgtttgttg ctgcagactt
       61 cctccgcccg ggccccagct cagtggagac aagttgcgcg tgggcaccat gaatcgcttg
      121 ggctcggtgc agcggaagat gccgtgcgtg tttgtgacgg aggtgaaagc tgagccttca
      181 gctaagcgag agcatcagcc atttaaagtt ttggcaactg aaacgctaag tgaaaaggca
      241 ttagatgcag atgtgtacaa tgcggttgca acagaaaaag tggatggaac atgttgttat
      301 gttactaact acaaaggtca gccatacctt tgggcgcgac tagatagaaa acctaacaag
      361 caagctgaca aaagatttaa aaaatttcta cattcaaaag aaaatgcaaa agagtttcat
      421 tggaacacgg aggaagactt caagcctgtc ccagagtgct ggataccagc aaaggaaata
      481 gaaaaacaga acgggaagcc agtgcctgat gaaaatggac acattcctgg ttgggtacca
      541 gtagaaaaga acagcaagca gtattgctgg cactcgtctg tagtgagcta tgagtttgga
      601 attgccctgg tactaaggca ccatcctgac gatcctgggg ttttggaaat tagtgctgtt
      661 cccctgtcag agcttttaga gcaaactctg gagctgatag gaacgaatat caatggaaac
      721 ccatatgggc taggaagcaa gaaataccca ttacattttc ttacaccaca tggggcattc
      781 caggtcagaa acctgcctac actgaaacac aatgacctgc tgtcctggtt tgaaggctgc
      841 agagagggtc aaatagaagg gattgtgtgg cattgcggtg acggctgttt aattaaggtc
      901 caccgccacc atcttggttt atgctggcca cttccggata cctacatgaa ctccaaacca
      961 gttattatta acatgaacct ggacaaatat gactgtgctt ttgatcacca gtctttgttt
     1021 aataagtttt caaaaataga taagcagaaa tttgataggc tcaaagatat aacccttgat
     1081 atataaaata gaaataatag ttgggactgt tgtgattttt ttattgggac aggtttgcca
     1141 tgtttacaca ggtcaattta tttttcctag ctgcttggca aaacacatgt caacttctaa
     1201 acatgtttct atgtatttat agaaatcatc gttaggtttg aataacttaa cacaaaaata
     1261 agtataaaat aatcaatttt aaatagtaag attgttataa gcttaccttt atgcttttag
     1321 agaatttaaa atatgaaaat aggaaatatt tatcatagct cattatatac tatatagtca
     1381 taaatttttg tcgtagctca ttatatacta tatagtcaca aattactgag gtcttcaaaa
     1441 atatactttt ctaacaagtt aaaactaaat atgattttat ttttaagcaa aataatacag
     1501 tattttgaga ggtaaattct gtaggtcaga gactgatttc cagctgaaac ttctatgtca
     1561 tcagtagttt taaatctaca gttttaaatg aggccattaa taaatcggga cgccattagg
     1621 actttctcca tcttcccgtt gttcagaagc agcaagtggg ctaggcaatt caaatccaaa
     1681 ttgttcagaa agtttgttta acttctcttc taagagaata tttttcttca cttcttcctt
     1741 ataattgtac ttcaggtctt caatttcttc aaagaatgaa gggtcaaaat tttccagttc
     1801 ttttttcagc tttttaattt cctcctaaaa attacataca ggatacatgt ttttggtttg
     1861 aaatttaaat ttgattgtaa acacgaaaac tcaaaatctt aaatattttt ctttatattt
     1921 taccgttcaa ggttccattg taccatgtgc ataatgtata agctgccatc tttggcttaa
     1981 ttttaagatt ggatctttaa actgcctcag atattctcag gcaagctaaa aggattttgc
     2041 tttttacaac atttaagatt tttcagtatt tttaatgttc tgatttttta cctttctatc
     2101 taatattgat gatcacggaa actctgggac ttgtaagagt tgagtacctg gtgaaggaga
     2161 gtgatgtgag cggtgtttac actaacagcg gtgagcagcc agggctcact tctagccatt
     2221 gtgtttctgg agtcttaagg gggaggacag aaatgattta aggtaaagat ccctgaaaat
     2281 aatttcaagg tgcttaaaaa acaccttttc caccatgacc cacaaattaa gaaaacagtt
     2341 aaaaaaaaaa aaaaaaaaaa aaaa
//
