LOCUS       NM_001106274            2289 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus retinaldehyde binding protein 1 (Rlbp1), mRNA.
ACCESSION   NM_001106274 XM_001064754 XM_006229396 XM_214973
VERSION     NM_001106274.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2289)
  AUTHORS   Daiger,S.P., Sullivan,L.S. and Bowne,S.J.
  TITLE     Genes and mutations causing retinitis pigmentosa
  JOURNAL   Clin Genet 84 (2), 132-141 (2013)
   PUBMED   23701314
  REMARK    Review article
REFERENCE   2  (bases 1 to 2289)
  AUTHORS   von Lintig,J., Kiser,P.D., Golczak,M. and Palczewski,K.
  TITLE     The biochemical and structural basis for trans-to-cis isomerization
            of retinoids in the chemistry of vision
  JOURNAL   Trends Biochem Sci 35 (7), 400-410 (2010)
   PUBMED   20188572
  REMARK    Review article
REFERENCE   3  (bases 1 to 2289)
  AUTHORS   Wright,A.F., Chakarova,C.F., Abd El-Aziz,M.M. and Bhattacharya,S.S.
  TITLE     Photoreceptor degeneration: genetic and mechanistic dissection of a
            complex trait
  JOURNAL   Nat Rev Genet 11 (4), 273-284 (2010)
   PUBMED   20212494
  REMARK    Review article
REFERENCE   4  (bases 1 to 2289)
  AUTHORS   Huang,J., Possin,D.E. and Saari,J.C.
  TITLE     Localizations of visual cycle components in retinal pigment
            epithelium
  JOURNAL   Mol Vis 15, 223-234 (2009)
   PUBMED   19180257
REFERENCE   5  (bases 1 to 2289)
  AUTHORS   Katsanis,N., Shroyer,N.F., Lewis,R.A., Cavender,J.C.,
            Al-Rajhi,A.A., Jabak,M. and Lupski,J.R.
  TITLE     Fundus albipunctatus and retinitis punctata albescens in a pedigree
            with an R150Q mutation in RLBP1
  JOURNAL   Clin Genet 59 (6), 424-429 (2001)
   PUBMED   11453974
REFERENCE   6  (bases 1 to 2289)
  AUTHORS   Burstedt,M.S., Forsman-Semb,K., Golovleva,I., Janunger,T.,
            Wachtmeister,L. and Sandgren,O.
  TITLE     Ocular phenotype of bothnia dystrophy, an autosomal recessive
            retinitis pigmentosa associated with an R234W mutation in the RLBP1
            gene
  JOURNAL   Arch Ophthalmol 119 (2), 260-267 (2001)
   PUBMED   11176989
REFERENCE   7  (bases 1 to 2289)
  AUTHORS   Maw,M.A., Kennedy,B., Knight,A., Bridges,R., Roth,K.E., Mani,E.J.,
            Mukkadan,J.K., Nancarrow,D., Crabb,J.W. and Denton,M.J.
  TITLE     Mutation of the gene encoding cellular retinaldehyde-binding
            protein in autosomal recessive retinitis pigmentosa
  JOURNAL   Nat Genet 17 (2), 198-200 (1997)
   PUBMED   9326942
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On or before Jun 4, 2021 this sequence version replaced
            XM_006229396.4, NM_001106274.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.1036427.1,
                                           SRR26643298.3530.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840106 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-358               JAXUCZ010000001.1  142731264-142731621 c
            359-469             JAXUCZ010000001.1  142729481-142729591 c
            470-498             JAXUCZ010000001.1  142728769-142728797 c
            499-627             JAXUCZ010000001.1  142728461-142728589 c
            628-832             JAXUCZ010000001.1  142726015-142726219 c
            833-1011            JAXUCZ010000001.1  142723835-142724013 c
            1012-1170           JAXUCZ010000001.1  142720774-142720932 c
            1171-1281           JAXUCZ010000001.1  142719448-142719558 c
            1282-2289           JAXUCZ010000001.1  142718262-142719269 c
FEATURES             Location/Qualifiers
     source          1..2289
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q31"
     gene            1..2289
                     /gene="Rlbp1"
                     /note="retinaldehyde binding protein 1"
                     /db_xref="GeneID:293049"
                     /db_xref="RGD:1309649"
     exon            1..358
                     /gene="Rlbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            359..469
                     /gene="Rlbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            470..498
                     /gene="Rlbp1"
                     /inference="alignment:Splign:2.1.0"
     CDS             487..1440
                     /gene="Rlbp1"
                     /codon_start=1
                     /product="retinaldehyde-binding protein 1"
                     /protein_id="NP_001099744.1"
                     /db_xref="GeneID:293049"
                     /db_xref="RGD:1309649"
                     /translation="MSEGVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHT
                     LQKAKDELNEREETRDEAVRELQELVQAQAASGEELAVAVAERVQARDSAFLLRFIRA
                     RKFDVGRAYELLKGYVNFRLQYPELFDSLSMEALRCTIEAGYPGVLSSRDKYGRVVML
                     FNIENWHCEEVTFDEILQAYCFILEKLLENEETQINGFCIVENFKGFTMQQAAGLRPS
                     DLKKMVDMLQDSFPARFKAIHFIHQPWYFTTTYNVVKPFLKNKLLQRVFVHGDDLDGF
                     FQEIDENILPADFGGTLPKYDGKVVAEQLFGPRVEVENTAL"
     exon            499..627
                     /gene="Rlbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            628..832
                     /gene="Rlbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            833..1011
                     /gene="Rlbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1012..1170
                     /gene="Rlbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1171..1281
                     /gene="Rlbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1282..2289
                     /gene="Rlbp1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcccaggctc ccctgcctcc cagtttgaga agagagaggg caggaaaatg agacggggct
       61 ggcccagatc ccagtgaagt agcttccaca tggccgaaca gagctccaag caggagctca
      121 caaagcaggg ctttgatggt ggccctgcag gcccggcctc tcccctctcc ctcagggtgc
      181 ttcgcttggt tcattctggg cctcccgtga gcctgattga atgggaaacg gtgggcctga
      241 gaagttcctt gtgacaagct aatcccagct tgctgacctg accacacctc caaaggaaac
      301 agcctcccga gctccagaac aattcaggca cccagtagcc ccaagaaaga gctatcaggg
      361 acggtcaagg ctcgggtgaa atcacacagc ttgcaagaca ggattggaat ccaagtccca
      421 tatcctgttc cttagccgct tcttggtgcc tacagaagtc acagcttagt gtcttcaaga
      481 ggcagtatgt cagagggggt gggcacattc cgaatggtcc ctgaagagga gcaggagctc
      541 cgggcacagc tagaacagct cacaaccaag gatcatggtc ctgtctttgg cccatgcagc
      601 cagctgcccc gccacacttt gcagaaggct aaggatgagc tgaatgaaag ggaggaaacc
      661 cgggatgagg cggtgaggga gctacaggag ctggtccagg cacaggcagc ttctggggaa
      721 gagttggccg tggcagtggc tgagagggtg caggcaagag acagcgcctt cctcctgcgc
      781 ttcatccgtg cccgaaagtt tgatgtgggc cgggcttatg agctgctcaa aggctatgtg
      841 aacttccggc tccagtaccc tgaactcttc gatagcctat ctatggaggc tctccgctgc
      901 actatcgagg ccggttaccc tggtgtcctt tccagtcggg acaagtatgg tcgagtggtt
      961 atgctcttca acattgaaaa ctggcactgt gaagaagtca cctttgatga gatcttacag
     1021 gcatattgtt tcattctgga gaaactgctg gagaacgagg aaacccaaat caacggcttc
     1081 tgtattgtgg agaacttcaa gggcttcacc atgcagcagg ccgcgggact ccgcccctcc
     1141 gatctcaaga agatggtgga catgctccag gattcattcc cagccaggtt caaagctatc
     1201 cacttcatcc accaaccatg gtacttcacc accacttaca atgtggtcaa gcccttcttg
     1261 aagaacaagt tgctacagag ggtcttcgtt catggagatg acctggacgg cttcttccag
     1321 gagattgatg agaatatctt gcctgctgac tttgggggta cactgcccaa gtatgacggc
     1381 aaagttgtcg ctgagcagct cttcggtccc cgggttgagg ttgagaacac agccttgtga
     1441 ggagatgccc taccatgtga tcctcattag catcccggcc cttcctcagc tttcctgaac
     1501 ccaaaacagg gaacggaacg cctgaggtga ctggtttccc cagccttccc taggtttagg
     1561 accgctctag tggcatctca tcccaaaccg acctagagga cagtgaggca caggcatgtc
     1621 tttttttttt tttttttttt tcctccattt ttcttttctt cggagatggg gaccgaaccc
     1681 aggaccttgc gcttgctagg caagcgctct accactgagc taaatcccca accccacagg
     1741 catgtcttta ataggagact tgtggggcag ctaaattccc atcagccttt gcggttacag
     1801 ggcaatgact ttgagagaag ttaggatttc acagactaat taggtggctt ctccgtgatt
     1861 gtctttgtaa tcgctttgat acttagggtg tgaaggtgag tgagaagctt acttgcaatt
     1921 cagttaaaaa aagaaagaga ggggcttaaa gctctaatga tcttagcagc agtgggcaga
     1981 taaggggttt cccacctaag attccaggga gggagtagca gccttagaac agttgtattt
     2041 ggggctgact tgcggatgaa cgccctgcgg atgaacgccc tcgtagctaa gagctctgga
     2101 ctctgtccag ggtagaagtc acgtcccttc ctctccatcc accgtaggtg tgatttttgg
     2161 ggccagggct cccattcact agatgctgtt tgctttgttg gatggtctta cttaaatgca
     2221 cctttgacat tgtccccaga cactcttagt ccttattaga caaataaaac cgttctttgt
     2281 cttgtgtca
//
